The membrane-proximal KXGFFKR motif of alpha-integrin mediates chemoresistance.

Liu CC, Leclair P, Yap SQ, Lim CJ
Mol Cell Biol. 2013 Nov;33(21):4334-45. doi: 10.1128/MCB.00580-13. Epub 2013 Sep 3. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

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ID	Plasmid	Purpose
81177	pcDNA 3.1 (+) Tacδ	Mammalian expression of human Tacδ (GFFKR cytoplasmic tail)
80019	pcDNA 3.1 (+) Tac-delta scr	Mammalian expression of Tac-delta scr
80018	pcDNA3.1-a4-delta tail	Mammalian expression of human integrin alpha4 with no tail
80017	pcDNA3.1-alpha4 wt (Hygro)	Mammalian expression of human integrin alpha4, Hygro selection
80016	pcDNA3.1-alpha4 wt	Mammalian expression of human integrin alpha4