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Human Smad3 and Smad4 are sequence-specific transcription activators.

Zawel L, Dai JL, Buckhaults P, Zhou S, Kinzler KW, Vogelstein B, Kern SE
Mol Cell. 1998 Mar . 1(4):611-7. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
16491pET-SMAD4
16492GST-Smad4-MH1
16493GST-Smad3-MH1
16495SBE4-LucLuciferase reporter containing four copies of the Smad binding site
16500SBE2-Luc
16501Vg4-Luc

Antibodies from Article