Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.
Wang S, Tsun ZY, Wolfson RL, Shen K, Wyant GA, Plovanich ME, Yuan ED, Jones TD, Chantranupong L, Comb W, Wang T, Bar-Peled L, Zoncu R, Straub C, Kim C, Park J, Sabatini BL, Sabatini DM
Science. 2015 Jan 9;347(6218):188-94. doi: 10.1126/science.1257132. Epub 2015 Jan 7.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 71855 | pRK5-FLAG-SLC38A9.1 | overexpression |
| 71858 | pLJM60-FLAG-SLC38A9.1 | lentiviral stable expression |
| 71861 | pLJM60-FLAG-SLC38A9.1 (delta110) | lentiviral stable expression |
| 71862 | pLJM60-FLAG-SLC38A9.1 (1-119aa) | lentiviral stable expression |
| 71863 | pLJM60-FLAG-SLC38A9.1 H60A | lentiviral stable expression |
| 71864 | pLJM60-FLAG-SLC38A9.1 I68A | lentiviral stable expression |
| 71865 | pLJM60-FLAG-SLC38A9.1 Y71A | lentiviral stable expression |
| 71866 | pLJM60-FLAG-SLC38A9.1 L74A | lentiviral stable expression |
| 71867 | pLJM60-FLAG-SLC38A9.1 P90A | lentiviral stable expression |
| 71868 | pRK5-LAMP1-FLAG | overexpression |
| 71869 | pRK5-HA-SLC38A9.1 | overexpression |