1227 pcDNA3 Myr HA Akt2 Citations (25)
Originally described in: AktUnpublished
Articles Citing 1227 pcDNA3 Myr HA Akt2
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Synthesis and evaluation of indazole based analog sensitive Akt inhibitors. Okuzumi T, Ducker GS, Zhang C, Aizenstein B, Hoffman R, Shokat KM. Mol Biosyst. 2010 Aug;6(8):1389-402. doi: 10.1039/c003917a. Epub 2010 Jun 28. PubMed |
Adiponectin inhibits osteoclastogenesis and bone resorption via APPL1-mediated suppression of Akt1. Tu Q, Zhang J, Dong LQ, Saunders E, Luo E, Tang J, Chen J. J Biol Chem. 2011 Apr 8;286(14):12542-53. doi: 10.1074/jbc.M110.152405. Epub 2011 Feb 7. PubMed |
Myotubularin regulates Akt-dependent survival signaling via phosphatidylinositol 3-phosphate. Razidlo GL, Katafiasz D, Taylor GS. J Biol Chem. 2011 Jun 3;286(22):20005-19. doi: 10.1074/jbc.M110.197749. Epub 2011 Apr 8. PubMed |
Akt mediates metastasis-associated gene 1 (MTA1) regulating the expression of E-cadherin and promoting the invasiveness of prostate cancer cells. Wang H, Fan L, Wei J, Weng Y, Zhou L, Shi Y, Zhou W, Ma D, Wang C. PLoS One. 2012;7(12):e46888. doi: 10.1371/journal.pone.0046888. Epub 2012 Dec 5. PubMed |
Insulin signaling via Akt2 switches plakophilin 1 function from stabilizing cell adhesion to promoting cell proliferation. Wolf A, Rietscher K, Glass M, Huttelmaier S, Schutkowski M, Ihling C, Sinz A, Wingenfeld A, Mun A, Hatzfeld M. J Cell Sci. 2013 Apr 15;126(Pt 8):1832-44. doi: 10.1242/jcs.118992. Epub 2013 Feb 26. PubMed |
Akt2 regulates metastatic potential in neuroblastoma. Qiao J, Lee S, Paul P, Qiao L, Taylor CJ, Schlegel C, Colon NC, Chung DH. PLoS One. 2013;8(2):e56382. doi: 10.1371/journal.pone.0056382. Epub 2013 Feb 26. PubMed |
The adherens junction protein afadin is an AKT substrate that regulates breast cancer cell migration. Elloul S, Kedrin D, Knoblauch NW, Beck AH, Toker A. Mol Cancer Res. 2014 Mar;12(3):464-76. doi: 10.1158/1541-7786.MCR-13-0398. Epub 2013 Nov 22. PubMed |
Evaluation of cancer stem cell markers CD133, CD44, CD24: association with AKT isoforms and radiation resistance in colon cancer cells. Sahlberg SH, Spiegelberg D, Glimelius B, Stenerlow B, Nestor M. PLoS One. 2014 Apr 23;9(4):e94621. doi: 10.1371/journal.pone.0094621. eCollection 2014. PubMed |
The activity of the anti-apoptotic fragment generated by the caspase-3/p120 RasGAP stress-sensing module displays strict Akt isoform specificity. Vanli G, Peltzer N, Dubuis G, Widmann C. Cell Signal. 2014 Dec;26(12):2992-7. doi: 10.1016/j.cellsig.2014.09.009. Epub 2014 Sep 22. PubMed |
Silencing of CDC42 inhibits neuroblastoma cell proliferation and transformation. Lee S, Craig BT, Romain CV, Qiao J, Chung DH. Cancer Lett. 2014 Dec 28;355(2):210-6. doi: 10.1016/j.canlet.2014.08.033. Epub 2014 Sep 28. PubMed |
The hepatitis B virus (HBV) HBx protein activates AKT to simultaneously regulate HBV replication and hepatocyte survival. Rawat S, Bouchard MJ. J Virol. 2015 Jan 15;89(2):999-1012. doi: 10.1128/JVI.02440-14. Epub 2014 Oct 29. PubMed |
PI3K-Akt signaling pathway upregulates hepatitis C virus RNA translation through the activation of SREBPs. Shi Q, Hoffman B, Liu Q. Virology. 2016 Mar;490:99-108. doi: 10.1016/j.virol.2016.01.012. Epub 2016 Feb 6. PubMed |
mTORC1 is necessary but mTORC2 and GSK3beta are inhibitory for AKT3-induced axon regeneration in the central nervous system. Miao L, Yang L, Huang H, Liang F, Ling C, Hu Y. Elife. 2016 Mar 30;5. pii: e14908. doi: 10.7554/eLife.14908. PubMed |
Intrinsic hepatocyte dedifferentiation is accompanied by upregulation of mesenchymal markers, protein sialylation and core alpha 1,6 linked fucosylation. Mehta A, Comunale MA, Rawat S, Casciano JC, Lamontagne J, Herrera H, Ramanathan A, Betesh L, Wang M, Norton P, Steel LF, Bouchard MJ. Sci Rep. 2016 Jun 22;6:27965. doi: 10.1038/srep27965. PubMed |
IRF5 and IRF5 Disease-Risk Variants Increase Glycolysis and Human M1 Macrophage Polarization by Regulating Proximal Signaling and Akt2 Activation. Hedl M, Yan J, Abraham C. Cell Rep. 2016 Aug 30;16(9):2442-55. doi: 10.1016/j.celrep.2016.07.060. Epub 2016 Aug 18. PubMed |
AKT1 and AKT2 isoforms play distinct roles during breast cancer progression through the regulation of specific downstream proteins. Riggio M, Perrone MC, Polo ML, Rodriguez MJ, May M, Abba M, Lanari C, Novaro V. Sci Rep. 2017 Mar 13;7:44244. doi: 10.1038/srep44244. PubMed |
Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system. Figlia G, Norrmen C, Pereira JA, Gerber D, Suter U. Elife. 2017 Sep 7;6. doi: 10.7554/eLife.29241. PubMed |
14-3-3 proteins regulate desmosomal adhesion via plakophilins. Rietscher K, Keil R, Jordan A, Hatzfeld M. J Cell Sci. 2018 May 22;131(10). pii: jcs.212191. doi: 10.1242/jcs.212191. PubMed |
Reduced insulin action in muscle of high fat diet rats over the diurnal cycle is not associated with defective insulin signaling. Small L, Brandon AE, Parker BL, Deshpande V, Samsudeen AF, Kowalski GM, Reznick J, Wilks DL, Preston E, Bruce CR, James DE, Turner N, Cooney GJ. Mol Metab. 2019 Jul;25:107-118. doi: 10.1016/j.molmet.2019.04.006. Epub 2019 Apr 12. PubMed |
Critical roles of ARHGAP36 as a signal transduction mediator of Shh pathway in lateral motor columnar specification. Nam H, Jeon S, An H, Yoo J, Lee HJ, Lee SK, Lee S. Elife. 2019 Jul 15;8. pii: 46683. doi: 10.7554/eLife.46683. PubMed |
MicroRNA‑149‑3p inhibits cell proliferation by targeting AKT2 in oral squamous cell carcinoma. Shen Q, Zhu H, Lei Q, Chen L, Yang D, Sui W. Mol Med Rep. 2021 Mar;23(3):172. doi: 10.3892/mmr.2020.11811. Epub 2021 Jan 5. PubMed |
Post-translational regulation of PGC-1alpha modulates fibrotic repair. Larson-Casey JL, Gu L, Davis D, Cai GQ, Ding Q, He C, Carter AB. FASEB J. 2021 Jun;35(6):e21675. doi: 10.1096/fj.202100339R. PubMed |
Targeting Gi/o protein-coupled receptor signaling blocks HER2-induced breast cancer development and enhances HER2-targeted therapy. Lyu C, Ye Y, Lensing MM, Wagner KU, Weigel RJ, Chen S. JCI Insight. 2021 Sep 22;6(18). pii: e150532. doi: 10.1172/jci.insight.150532. PubMed |
AKT1 mediates multiple phosphorylation events that functionally promote HSF1 activation. Lu WC, Omari R, Ray H, Wang J, Williams I, Jacobs C, Hockaden N, Bochman ML, Carpenter RL. FEBS J. 2022 Jul;289(13):3876-3893. doi: 10.1111/febs.16375. Epub 2022 Feb 11. PubMed |
SH003 and Docetaxel Show Synergistic Anticancer Effects by Inhibiting EGFR Activation in Triple-Negative Breast Cancer. Choi YJ, Lee K, Yoon JH, Cho SG, Kim YG, Jeong M, Hwang HH, Lee SY, Jung SE, Ko SG. Biomed Res Int. 2022 May 5;2022:3647900. doi: 10.1155/2022/3647900. eCollection 2022. PubMed |
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