pAAV-EF1a-FLuc-WPRE-HGHpA Citations (4)

Originally described in: Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.
Paulk NK, Pekrun K, Zhu E, Nygaard S, Li B, Xu J, Chu K, Leborgne C, Dane AP, Haft A, Zhang Y, Zhang F, Morton C, Valentine MB, Davidoff AM, Nathwani AC, Mingozzi F, Grompe M, Alexander IE, Lisowski L, Kay MA Mol Ther. 2017 Sep 25. pii: S1525-0016(17)30437-9. doi: 10.1016/j.ymthe.2017.09.021. PubMed Journal

Articles Citing pAAV-EF1a-FLuc-WPRE-HGHpA

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Comprehensive mutagenesis maps the effect of all single-codon mutations in the AAV2 rep gene on AAV production. Jain NK, Ogden PJ, Church GM. Elife. 2024 Mar 27;12:RP87730. doi: 10.7554/eLife.87730. PubMed
The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner. Gonzalez-Sandoval A, Pekrun K, Tsuji S, Zhang F, Hung KL, Chang HY, Kay MA. Nat Commun. 2023 Apr 28;14(1):2448. doi: 10.1038/s41467-023-38106-3. PubMed Associated Plasmids AAV-AM
Methods Matter: Standard Production Platforms for Recombinant AAV Produce Chemically and Functionally Distinct Vectors. Rumachik NG, Malaker SA, Poweleit N, Maynard LH, Adams CM, Leib RD, Cirolia G, Thomas D, Stamnes S, Holt K, Sinn P, May AP, Paulk NK. Mol Ther Methods Clin Dev. 2020 May 22;18:98-118. doi: 10.1016/j.omtm.2020.05.018. eCollection 2020 Sep 11. PubMed Associated Plasmids ssAAV-EF1a-FLuc-WPRE-HgHpA_bac_293
Using a barcoded AAV capsid library to select for clinically relevant gene therapy vectors. Pekrun K, De Alencastro G, Luo QJ, Liu J, Kim Y, Nygaard S, Galivo F, Zhang F, Song R, Tiffany MR, Xu J, Hebrok M, Grompe M, Kay MA. JCI Insight. 2019 Nov 14;4(22). pii: 131610. doi: 10.1172/jci.insight.131610. PubMed Associated Plasmids pscAAV-CAG-GFP pAAV-CAG-FLuc AAV-KP1

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