Using a barcoded AAV capsid library to select for clinically relevant gene therapy vectors.
Pekrun K, De Alencastro G, Luo QJ, Liu J, Kim Y, Nygaard S, Galivo F, Zhang F, Song R, Tiffany MR, Xu J, Hebrok M, Grompe M, Kay MA
JCI Insight. 2019 Nov 14;4(22). pii: 131610. doi: 10.1172/jci.insight.131610.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
83279 | pscAAV-CAG-GFP | recombinant AAV vector packaging self-complementary GFP under the CAG promoter |
83281 | pAAV-CAG-FLuc | recombinant AAV vector packaging single-stranded Firefly Luciferase under the CAG promoter (includes WPRE element) |
206504 | AAV-KP1 | AAV packaging vector containing AAV2 rep and KP1 cap and partial AAV2 p5 promoter |