pLV-hTERT-IRES-hygro Citations (28)
Originally described in: Engulfed cadherin fingers are polarized junctional structures between collectively migrating endothelial cells.Hayer A, Shao L, Chung M, Joubert LM, Yang HW, Tsai FC, Bisaria A, Betzig E, Meyer T Nat Cell Biol. 2016 Dec;18(12):1311-1323. doi: 10.1038/ncb3438. Epub 2016 Nov 14. PubMed Journal
Articles Citing pLV-hTERT-IRES-hygro
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Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes. Burrage LC, Reynolds JJ, Baratang NV, Phillips JB, Wegner J, McFarquhar A, Higgs MR, Christiansen AE, Lanza DG, Seavitt JR, Jain M, Li X, Parry DA, Raman V, Chitayat D, Chinn IK, Bertuch AA, Karaviti L, Schlesinger AE, Earl D, Bamshad M, Savarirayan R, Doddapaneni H, Muzny D, Jhangiani SN, Eng CM, Gibbs RA, Bi W, Emrick L, Rosenfeld JA, Postlethwait J, Westerfield M, Dickinson ME, Beaudet AL, Ranza E, Huber C, Cormier-Daire V, Shen W, Mao R, Heaney JD, Orange JS, Bertola D, Yamamoto GL, Baratela WAR, Butler MG, Ali A, Adeli M, Cohn DH, Krakow D, Jackson AP, Lees M, Offiah AC, Carlston CM, Carey JC, Stewart GS, Bacino CA, Campeau PM, Lee B. Am J Hum Genet. 2019 Mar 7;104(3):422-438. doi: 10.1016/j.ajhg.2019.01.007. Epub 2019 Feb 14. PubMed |
JC Virus infected choroid plexus epithelial cells produce extracellular vesicles that infect glial cells independently of the virus attachment receptor. O'Hara BA, Morris-Love J, Gee GV, Haley SA, Atwood WJ. PLoS Pathog. 2020 Mar 4;16(3):e1008371. doi: 10.1371/journal.ppat.1008371. eCollection 2020 Mar. PubMed |
Trophectoderm-Specific Knockdown of LIN28 Decreases Expression of Genes Necessary for Cell Proliferation and Reduces Elongation of Sheep Conceptus. Ali A, Stenglein MD, Spencer TE, Bouma GJ, Anthony RV, Winger QA. Int J Mol Sci. 2020 Apr 6;21(7). pii: ijms21072549. doi: 10.3390/ijms21072549. PubMed |
Immortalization of human primary prostate epithelial cells via CRISPR inactivation of the CDKN2A locus and expression of telomerase. Zhao Z, Fowle H, Valentine H, Liu Z, Tan Y, Pei J, Badal S, Testa JR, Grana X. Prostate Cancer Prostatic Dis. 2021 Mar;24(1):233-243. doi: 10.1038/s41391-020-00274-4. Epub 2020 Sep 1. PubMed |
A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans. Chansel-Da Cruz M, Hohl M, Ceppi I, Kermasson L, Maggiorella L, Modesti M, de Villartay JP, Ileri T, Cejka P, Petrini JHJ, Revy P. Cell Rep. 2020 Dec 29;33(13):108559. doi: 10.1016/j.celrep.2020.108559. PubMed |
LMO2 upregulation due to AR deactivation in cancer-associated fibroblasts induces non-cell-autonomous growth of prostate cancer after androgen deprivation. Chen L, Wang YY, Li D, Wang C, Wang SY, Shao SH, Zhu ZY, Zhao J, Zhang Y, Ruan Y, Han BM, Xia SJ, Jiang CY, Zhao FJ. Cancer Lett. 2021 Apr 10;503:138-150. doi: 10.1016/j.canlet.2021.01.017. Epub 2021 Jan 24. PubMed |
HIF-1alpha and Pro-Inflammatory Signaling Improves the Immunomodulatory Activity of MSC-Derived Extracellular Vesicles. Gomez-Ferrer M, Villanueva-Badenas E, Sanchez-Sanchez R, Sanchez-Lopez CM, Baquero MC, Sepulveda P, Dorronsoro A. Int J Mol Sci. 2021 Mar 26;22(7). pii: ijms22073416. doi: 10.3390/ijms22073416. PubMed |
A robust vasculogenic microfluidic model using human immortalized endothelial cells and Thy1 positive fibroblasts. Wan Z, Zhang S, Zhong AX, Shelton SE, Campisi M, Sundararaman SK, Offeddu GS, Ko E, Ibrahim L, Coughlin MF, Liu T, Bai J, Barbie DA, Kamm RD. Biomaterials. 2021 Sep;276:121032. doi: 10.1016/j.biomaterials.2021.121032. Epub 2021 Jul 16. PubMed |
Teriflunomide Inhibits JCPyV Infection and Spread in Glial Cells and Choroid Plexus Epithelial Cells. O'Hara BA, Gee GV, Haley SA, Morris-Love J, Nyblade C, Nieves C, Hanson BA, Dang X, Turner TJ, Chavin JM, Lublin A, Koralnik IJ, Atwood WJ. Int J Mol Sci. 2021 Sep 10;22(18). pii: ijms22189809. doi: 10.3390/ijms22189809. PubMed |
Analysis of Telomere Maintenance Related Genes Reveals NOP10 as a New Metastatic-Risk Marker in Pheochromocytoma/Paraganglioma. Monteagudo M, Martinez P, Leandro-Garcia LJ, Martinez-Montes AM, Calsina B, Pulgarin-Alfaro M, Diaz-Talavera A, Mellid S, Leton R, Gil E, Perez-Martinez M, Megias D, Torres-Ruiz R, Rodriguez-Perales S, Gonzalez P, Caleiras E, Jimenez-Villa S, Roncador G, Alvarez-Escola C, Regojo RM, Calatayud M, Guadalix S, Curras-Freixes M, Rapizzi E, Canu L, Nolting S, Remde H, Fassnacht M, Bechmann N, Eisenhofer G, Mannelli M, Beuschlein F, Quinkler M, Rodriguez-Antona C, Cascon A, Blasco MA, Montero-Conde C, Robledo M. Cancers (Basel). 2021 Sep 23;13(19). pii: cancers13194758. doi: 10.3390/cancers13194758. PubMed |
HIF-Overexpression and Pro-Inflammatory Priming in Human Mesenchymal Stromal Cells Improves the Healing Properties of Extracellular Vesicles in Experimental Crohn's Disease. Gomez-Ferrer M, Amaro-Prellezo E, Dorronsoro A, Sanchez-Sanchez R, Vicente A, Cosin-Roger J, Barrachina MD, Baquero MC, Valencia J, Sepulveda P. Int J Mol Sci. 2021 Oct 19;22(20). pii: ijms222011269. doi: 10.3390/ijms222011269. PubMed |
RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1. Abu-Libdeh B, Jhujh SS, Dhar S, Sommers JA, Datta A, Longo GM, Grange LJ, Reynolds JJ, Cooke SL, McNee GS, Hollingworth R, Woodward BL, Ganesh AN, Smerdon SJ, Nicolae CM, Durlacher-Betzer K, Molho-Pessach V, Abu-Libdeh A, Meiner V, Moldovan GL, Roukos V, Harel T, Brosh RM Jr, Stewart GS. J Clin Invest. 2022 Mar 1;132(5). pii: 147301. doi: 10.1172/JCI147301. PubMed |
Myoepithelial progenitors as founder cells of hyperplastic human breast lesions upon PIK3CA transformation. Goldhammer N, Kim J, Villadsen R, Ronnov-Jessen L, Petersen OW. Commun Biol. 2022 Mar 10;5(1):219. doi: 10.1038/s42003-022-03161-x. PubMed |
Patient-Specific Sarcoma Organoids for Personalized Translational Research: Unification of the Operating Room with Rare Cancer Research and Clinical Implications. Forsythe SD, Sivakumar H, Erali RA, Wajih N, Li W, Shen P, Levine EA, Miller KE, Skardal A, Votanopoulos KI. Ann Surg Oncol. 2022 Nov;29(12):7354-7367. doi: 10.1245/s10434-022-12086-y. Epub 2022 Jul 3. PubMed |
Modeling a Novel Variant of Glycogenosis IXa Using a Clonal Inducible Reprogramming System to Generate "Diseased" Hepatocytes for Accurate Diagnosis. Garcia-Llorens G, Lopez-Navarro S, Jaijo T, Castell JV, Bort R. J Pers Med. 2022 Jul 7;12(7):1111. doi: 10.3390/jpm12071111. PubMed |
Generation of an Immortalized Human Adipose-Derived Mesenchymal Stromal Cell Line Suitable for Wound Healing Therapy. Iacomi DM, Rosca AM, Tutuianu R, Neagu TP, Pruna V, Simionescu M, Titorencu I. Int J Mol Sci. 2022 Aug 10;23(16):8925. doi: 10.3390/ijms23168925. PubMed |
Pathogenic variants in SLF2 and SMC5 cause segmented chromosomes and mosaic variegated hyperploidy. Grange LJ, Reynolds JJ, Ullah F, Isidor B, Shearer RF, Latypova X, Baxley RM, Oliver AW, Ganesh A, Cooke SL, Jhujh SS, McNee GS, Hollingworth R, Higgs MR, Natsume T, Khan T, Martos-Moreno GA, Chupp S, Mathew CG, Parry D, Simpson MA, Nahavandi N, Yuksel Z, Drasdo M, Kron A, Vogt P, Jonasson A, Seth SA, Gonzaga-Jauregui C, Brigatti KW, Stegmann APA, Kanemaki M, Josifova D, Uchiyama Y, Oh Y, Morimoto A, Osaka H, Ammous Z, Argente J, Matsumoto N, Stumpel CTRM, Taylor AMR, Jackson AP, Bielinsky AK, Mailand N, Le Caignec C, Davis EE, Stewart GS. Nat Commun. 2022 Nov 4;13(1):6664. doi: 10.1038/s41467-022-34349-8. PubMed |
Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient. Valentine H, Aiken W, Morrison B, Zhao Z, Fowle H, Wasserman JS, Thompson E, Chin W, Young M, Clarke S, Gibbs D, Harrison S, McLaughlin W, Kwok T, Jin F, Campbell KS, Horvath A, Thompson R, Lee NH, Zhou Y, Grana X, Ragin C, Badal S. Cancer Res Commun. 2022 Nov;2(11):1355-1371. doi: 10.1158/2767-9764.crc-22-0245. Epub 2022 Nov 7. PubMed |
Immortalization of mouse primary astrocytes. Yi W, Yang D, Xu Z, Chen Z, Xiao G, Qin L. Gene. 2023 May 20;865:147327. doi: 10.1016/j.gene.2023.147327. Epub 2023 Mar 2. PubMed |
A robust reprogramming strategy for generating hepatocyte-like cells usable in pharmaco-toxicological studies. Garcia-Llorens G, Martinez-Sena T, Pareja E, Tolosa L, Castell JV, Bort R. Stem Cell Res Ther. 2023 Apr 18;14(1):94. doi: 10.1186/s13287-023-03311-w. PubMed |
Human cytomegalovirus attenuates AKT activity by destabilizing insulin receptor substrate proteins. Domma AJ, Goodrum FD, Moorman NJ, Kamil JP. bioRxiv. 2023 Apr 17:2023.04.17.537203. doi: 10.1101/2023.04.17.537203. Preprint. PubMed |
Actin nucleators safeguard replication forks by limiting nascent strand degradation. Nieminuszczy J, Martin PR, Broderick R, Krwawicz J, Kanellou A, Mocanu C, Bousgouni V, Smith C, Wen KK, Woodward BL, Bakal C, Shackley F, Aguilera A, Stewart GS, Vyas YM, Niedzwiedz W. Nucleic Acids Res. 2023 Jul 7;51(12):6337-6354. doi: 10.1093/nar/gkad369. PubMed |
Co-cultures of colon cancer cells and cancer-associated fibroblasts recapitulate the aggressive features of mesenchymal-like colon cancer. Strating E, Verhagen MP, Wensink E, Dunnebach E, Wijler L, Aranguren I, De la Cruz AS, Peters NA, Hageman JH, van der Net MMC, van Schelven S, Laoukili J, Fodde R, Roodhart J, Nierkens S, Snippert H, Gloerich M, Rinkes IB, Elias SG, Kranenburg O. Front Immunol. 2023 May 16;14:1053920. doi: 10.3389/fimmu.2023.1053920. eCollection 2023. PubMed |
Human cytomegalovirus attenuates AKT activity by destabilizing insulin receptor substrate proteins. Domma AJ, Henderson LA, Goodrum FD, Moorman NJ, Kamil JP. J Virol. 2023 Oct 31;97(10):e0056323. doi: 10.1128/jvi.00563-23. Epub 2023 Sep 27. PubMed |
R-Loop Accumulation in Spliceosome Mutant Leukemias Confers Sensitivity to PARP1 Inhibition by Triggering Transcription-Replication Conflicts. Liu ZS, Sinha S, Bannister M, Song A, Arriaga-Gomez E, McKeeken AJ, Bonner EA, Hanson BK, Sarchi M, Takashima K, Zong D, Corral VM, Nguyen E, Yoo J, Chiraphapphaiboon W, Leibson C, McMahon MC, Rai S, Swisher EM, Sachs Z, Chatla S, Stirewalt DL, Deeg HJ, Skorski T, Papapetrou EP, Walter MJ, Graubert TA, Doulatov S, Lee SC, Nguyen HD. Cancer Res. 2024 Feb 15;84(4):577-597. doi: 10.1158/0008-5472.CAN-23-3239. PubMed |
Single-genome analysis reveals heterogeneous association of the Herpes Simplex Virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts. Francois AK, Rohani A, Loftus M, Dochnal S, Hrit J, McFarlane S, Whitford A, Lewis A, Krakowiak P, Boutell C, Rothbart SB, Kashatus D, Cliffe AR. bioRxiv [Preprint]. 2023 Dec 3:2023.12.03.569766. doi: 10.1101/2023.12.03.569766. PubMed |
Single-genome analysis reveals a heterogeneous association of the herpes simplex virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts. Francois AK, Rohani A, Loftus M, Dochnal S, Hrit J, McFarlane S, Whitford A, Lewis A, Krakowiak P, Boutell C, Rothbart SB, Kashatus D, Cliffe AR. mBio. 2024 Apr 10;15(4):e0327823. doi: 10.1128/mbio.03278-23. Epub 2024 Feb 27. PubMed |
Extracellular vesicles from dental pulp mesenchymal stem cells modulate macrophage phenotype during acute and chronic cardiac inflammation in athymic nude rats with myocardial infarction. Amaro-Prellezo E, Gomez-Ferrer M, Hakobyan L, Ontoria-Oviedo I, Peiro-Molina E, Tarazona S, Salguero P, Ruiz-Sauri A, Selva-Roldan M, Vives-Sanchez R, Sepulveda P. Inflamm Regen. 2024 May 28;44(1):25. doi: 10.1186/s41232-024-00340-7. PubMed |
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