pLV-EF1a-IRES-Puro Citations (56)
Originally described in: Engulfed cadherin fingers are polarized junctional structures between collectively migrating endothelial cells.Hayer A, Shao L, Chung M, Joubert LM, Yang HW, Tsai FC, Bisaria A, Betzig E, Meyer T Nat Cell Biol. 2016 Dec;18(12):1311-1323. doi: 10.1038/ncb3438. Epub 2016 Nov 14. PubMed Journal
Articles Citing pLV-EF1a-IRES-Puro
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| Role of PDGF receptor-alpha during human cytomegalovirus entry into fibroblasts. Wu K, Oberstein A, Wang W, Shenk T. Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):E9889-E9898. doi: 10.1073/pnas.1806305115. Epub 2018 Oct 1. PubMed |
| MicroRNA-375 Suppresses the Growth and Invasion of Fibrolamellar Carcinoma. Dinh TA, Jewell ML, Kanke M, Francisco A, Sritharan R, Turnham RE, Lee S, Kastenhuber ER, Wauthier E, Guy CD, Yeung RS, Lowe SW, Reid LM, Scott JD, Diehl AM, Sethupathy P. Cell Mol Gastroenterol Hepatol. 2019;7(4):803-817. doi: 10.1016/j.jcmgh.2019.01.008. Epub 2019 Feb 11. PubMed |
Identification of new transmembrane proteins concentrated at the nuclear envelope using organellar proteomics of mesenchymal cells.
Cheng LC, Baboo S, Lindsay C, Brusman L, Martinez-Bartolome S, Tapia O, Zhang X, Yates JR 3rd, Gerace L.
Nucleus. 2019 Dec;10(1):126-143. doi: 10.1080/19491034.2019.1618175.
PubMed
Associated Plasmids |
| Pathogenic Bi-allelic Mutations in NDUFAF8 Cause Leigh Syndrome with an Isolated Complex I Deficiency. Alston CL, Veling MT, Heidler J, Taylor LS, Alaimo JT, Sung AY, He L, Hopton S, Broomfield A, Pavaine J, Diaz J, Leon E, Wolf P, McFarland R, Prokisch H, Wortmann SB, Bonnen PE, Wittig I, Pagliarini DJ, Taylor RW. Am J Hum Genet. 2020 Jan 2;106(1):92-101. doi: 10.1016/j.ajhg.2019.12.001. Epub 2019 Dec 19. PubMed |
| Hepatic PLIN5 signals via SIRT1 to promote autophagy and prevent inflammation during fasting. Zhang E, Cui W, Lopresti M, Mashek MT, Najt CP, Hu H, Mashek DG. J Lipid Res. 2020 Mar;61(3):338-350. doi: 10.1194/jlr.RA119000336. Epub 2020 Jan 13. PubMed |
| CD226(hi)CD8(+) T Cells Are a Prerequisite for Anti-TIGIT Immunotherapy. Jin HS, Ko M, Choi DS, Kim JH, Lee DH, Kang SH, Kim I, Lee HJ, Choi EK, Kim KP, Yoo C, Park Y. Cancer Immunol Res. 2020 Jul;8(7):912-925. doi: 10.1158/2326-6066.CIR-19-0877. Epub 2020 Apr 7. PubMed |
| Hotspots of Aberrant Enhancer Activity in Fibrolamellar Carcinoma Reveal Candidate Oncogenic Pathways and Therapeutic Vulnerabilities. Dinh TA, Sritharan R, Smith FD, Francisco AB, Ma RK, Bunaciu RP, Kanke M, Danko CG, Massa AP, Scott JD, Sethupathy P. Cell Rep. 2020 Apr 14;31(2):107509. doi: 10.1016/j.celrep.2020.03.073. PubMed |
| A viral fusogen hijacks the actin cytoskeleton to drive cell-cell fusion. Chan KMC, Son S, Schmid EM, Fletcher DA. Elife. 2020 May 22;9. pii: 51358. doi: 10.7554/eLife.51358. PubMed |
Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival.
Fukuda Y, Pazyra-Murphy MF, Silagi ES, Tasdemir-Yilmaz OE, Li Y, Rose L, Yeoh ZC, Vangos NE, Geffken EA, Seo HS, Adelmant G, Bird GH, Walensky LD, Marto JA, Dhe-Paganon S, Segal RA.
J Cell Biol. 2021 Jan 4;220(1). pii: 211577. doi: 10.1083/jcb.202005051.
PubMed
Associated Plasmids |
Intracellular arginine-dependent translation sensor reveals the dynamics of arginine starvation response and resistance in ASS1-negative cells.
Rogers LC, Zhou J, Baker A, Schutt CR, Panda PK, Van Tine BA.
Cancer Metab. 2021 Jan 21;9(1):4. doi: 10.1186/s40170-021-00238-9.
PubMed
Associated Plasmids |
| Evasion of Innate Immunity Contributes to Small Cell Lung Cancer Progression and Metastasis. Zhu M, Huang Y, Bender ME, Girard L, Kollipara R, Eglenen-Polat B, Naito Y, Savage TK, Huffman KE, Koyama S, Kumanogoh A, Minna JD, Johnson JE, Akbay EA. Cancer Res. 2021 Apr 1;81(7):1813-1826. doi: 10.1158/0008-5472.CAN-20-2808. Epub 2021 Jan 25. PubMed |
| A comparative analysis of SARS-CoV-2 antivirals characterizes 3CL(pro) inhibitor PF-00835231 as a potential new treatment for COVID-19. de Vries M, Mohamed AS, Prescott RA, Valero-Jimenez AM, Desvignes L, O'Connor R, Steppan C, Devlin JC, Ivanova E, Herrera A, Schinlever A, Loose P, Ruggles K, Koralov SB, Anderson AS, Binder J, Dittmann M. J Virol. 2021 Feb 23. pii: JVI.01819-20. doi: 10.1128/JVI.01819-20. PubMed |
| Proliferation of Highly Cytotoxic Human Natural Killer Cells by OX40L Armed NK-92 With Secretory Neoleukin-2/15 for Cancer Immunotherapy. Guo M, Sun C, Qian Y, Zhu L, Ta N, Wang G, Zheng J, Guo F, Liu Y. Front Oncol. 2021 Apr 15;11:632540. doi: 10.3389/fonc.2021.632540. eCollection 2021. PubMed |
| Identification of Autophagy-Related Genes as Targets for Senescence Induction Using a Customizable CRISPR-Based Suicide Switch Screen. Schepers A, Jochems F, Lieftink C, Wang L, Pogacar Z, Leite de Oliveira R, De Conti G, Beijersbergen RL, Bernards R. Mol Cancer Res. 2021 Jun 22. pii: 1541-7786.MCR-21-0146. doi: 10.1158/1541-7786.MCR-21-0146. PubMed |
| Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell. Puray-Chavez M, LaPak KM, Schrank TP, Elliott JL, Bhatt DP, Agajanian MJ, Jasuja R, Lawson DQ, Davis K, Rothlauf PW, Liu Z, Jo H, Lee N, Tenneti K, Eschbach JE, Shema Mugisha C, Cousins EM, Cloer EW, Vuong HR, VanBlargan LA, Bailey AL, Gilchuk P, Crowe JE Jr, Diamond MS, Hayes DN, Whelan SPJ, Horani A, Brody SL, Goldfarb D, Major MB, Kutluay SB. Cell Rep. 2021 Jul 13;36(2):109364. doi: 10.1016/j.celrep.2021.109364. Epub 2021 Jun 23. PubMed |
| Allo-Specific Humoral Responses: New Methods for Screening Donor-Specific Antibody and Characterization of HLA-Specific Memory B Cells. Song S, Manook M, Kwun J, Jackson AM, Knechtle SJ, Kelsoe G. Front Immunol. 2021 Jul 13;12:705140. doi: 10.3389/fimmu.2021.705140. eCollection 2021. PubMed |
| Methodological Development of a Multi-Readout Assay for the Assessment of Antiviral Drugs against SARS-CoV-2. Hahn F, Hage S, Herrmann A, Wangen C, Kicuntod J, Jungnickl D, Tillmanns J, Muller R, Fraedrich K, Uberla K, Kohlhof H, Ensser A, Marschall M. Pathogens. 2021 Aug 25;10(9). pii: pathogens10091076. doi: 10.3390/pathogens10091076. PubMed |
| A prenylated dsRNA sensor protects against severe COVID-19. Wickenhagen A, Sugrue E, Lytras S, Kuchi S, Noerenberg M, Turnbull ML, Loney C, Herder V, Allan J, Jarmson I, Cameron-Ruiz N, Varjak M, Pinto RM, Lee JY, Iselin L, Palmalux N, Stewart DG, Swingler S, Greenwood EJD, Crozier TWM, Gu Q, Davies EL, Clohisey S, Wang B, Trindade Maranhao Costa F, Freire Santana M, de Lima Ferreira LC, Murphy L, Fawkes A, Meynert A, Grimes G, Da Silva Filho JL, Marti M, Hughes J, Stanton RJ, Wang ECY, Ho A, Davis I, Jarrett RF, Castello A, Robertson DL, Semple MG, Openshaw PJM, Palmarini M, Lehner PJ, Baillie JK, Rihn SJ, Wilson SJ. Science. 2021 Oct 29;374(6567):eabj3624. doi: 10.1126/science.abj3624. Epub 2021 Oct 29. PubMed |
| Cloning of a Passage-Free SARS-CoV-2 Genome and Mutagenesis Using Red Recombination. Herrmann A, Jungnickl D, Cordsmeier A, Peter AS, Uberla K, Ensser A. Int J Mol Sci. 2021 Sep 22;22(19). pii: ijms221910188. doi: 10.3390/ijms221910188. PubMed |
| Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis. Kunisky AK, Anyaeche VI, Herron RS, Park CY, Hwang HW. Cell Rep. 2021 Oct 12;37(2):109815. doi: 10.1016/j.celrep.2021.109815. PubMed |
| Lack of CD8(+) T cell effector differentiation during priming mediates checkpoint blockade resistance in non-small cell lung cancer. Horton BL, Morgan DM, Momin N, Zagorulya M, Torres-Mejia E, Bhandarkar V, Wittrup KD, Love JC, Spranger S. Sci Immunol. 2021 Oct 29;6(64):eabi8800. doi: 10.1126/sciimmunol.abi8800. Epub 2021 Oct 29. PubMed |
| Type I interferon activates MHC class I-dressed CD11b(+) conventional dendritic cells to promote protective anti-tumor CD8(+) T cell immunity. Duong E, Fessenden TB, Lutz E, Dinter T, Yim L, Blatt S, Bhutkar A, Wittrup KD, Spranger S. Immunity. 2022 Feb 8;55(2):308-323.e9. doi: 10.1016/j.immuni.2021.10.020. Epub 2021 Nov 19. PubMed |
| Spike residue 403 affects binding of coronavirus spikes to human ACE2. Zech F, Schniertshauer D, Jung C, Herrmann A, Cordsmeier A, Xie Q, Nchioua R, Prelli Bozzo C, Volcic M, Koepke L, Muller JA, Kruger J, Heller S, Stenger S, Hoffmann M, Pohlmann S, Kleger A, Jacob T, Conzelmann KK, Ensser A, Sparrer KMJ, Kirchhoff F. Nat Commun. 2021 Nov 25;12(1):6855. doi: 10.1038/s41467-021-27180-0. PubMed |
| A cell-based multiplex immunoassay platform using fluorescent protein-barcoded reporter cell lines. Song S, Manook M, Kwun J, Jackson AM, Knechtle SJ, Kelsoe G. Commun Biol. 2021 Nov 25;4(1):1338. doi: 10.1038/s42003-021-02881-w. PubMed |
| SARS-CoV-2 treatment effects induced by ACE2-expressing microparticles are explained by the oxidized cholesterol-increased endosomal pH of alveolar macrophages. Wang Z, Lv J, Yu P, Qu Y, Zhou Y, Zhou L, Zhu Q, Li S, Song J, Deng W, Gao R, Liu Y, Liu J, Tong WM, Qin C, Huang B. Cell Mol Immunol. 2022 Feb;19(2):210-221. doi: 10.1038/s41423-021-00813-6. Epub 2022 Jan 4. PubMed |
| ER stress-induced cell death proceeds independently of the TRAIL-R2 signaling axis in pancreatic beta cells. Hagenlocher C, Siebert R, Taschke B, Wieske S, Hausser A, Rehm M. Cell Death Discov. 2022 Jan 24;8(1):34. doi: 10.1038/s41420-022-00830-y. PubMed |
| Gasdermin E mediates resistance of pancreatic adenocarcinoma to enzymatic digestion through a YBX1-mucin pathway. Lv J, Liu Y, Mo S, Zhou Y, Chen F, Cheng F, Li C, Saimi D, Liu M, Zhang H, Tang K, Ma J, Wang Z, Zhu Q, Tong WM, Huang B. Nat Cell Biol. 2022 Mar;24(3):364-372. doi: 10.1038/s41556-022-00857-4. Epub 2022 Mar 15. PubMed |
| A leukemia-protective germline variant mediates chromatin module formation via transcription factor nucleation. Llimos G, Gardeux V, Koch U, Kribelbauer JF, Hafner A, Alpern D, Pezoldt J, Litovchenko M, Russeil J, Dainese R, Moia R, Mahmoud AM, Rossi D, Gaidano G, Plass C, Lutsik P, Gerhauser C, Waszak SM, Boettiger A, Radtke F, Deplancke B. Nat Commun. 2022 Apr 19;13(1):2042. doi: 10.1038/s41467-022-29625-6. PubMed |
| PRC2-Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1-Targeted Therapy via Enhanced Viral Mimicry. Patel AJ, Warda S, Maag JLV, Misra R, Miranda-Roman MA, Pachai MR, Lee CJ, Li D, Wang N, Bayshtok G, Fishinevich E, Meng Y, Wong EWP, Yan J, Giff E, Pappalardi MB, McCabe MT, Fletcher JA, Rudin CM, Chandarlapaty S, Scandura JM, Koche RP, Glass JL, Antonescu CR, Zheng D, Chen Y, Chi P. Cancer Discov. 2022 Sep 2;12(9):2120-2139. doi: 10.1158/2159-8290.CD-21-1671. PubMed |
| TDO2 and tryptophan metabolites promote kynurenine/AhR signals to facilitate glioma progression and immunosuppression. Zhong C, Peng L, Tao B, Yin S, Lyu L, Ding H, Yang X, Peng T, He H, Zhou P. Am J Cancer Res. 2022 Jun 15;12(6):2558-2575. eCollection 2022. PubMed |
| MicroRNA-21 is immunosuppressive and pro-metastatic via separate mechanisms. Chi LH, Cross RSN, Redvers RP, Davis M, Hediyeh-Zadeh S, Mathivanan S, Samuel M, Lucas EC, Mouchemore K, Gregory PA, Johnstone CN, Anderson RL. Oncogenesis. 2022 Jul 11;11(1):38. doi: 10.1038/s41389-022-00413-7. PubMed |
Shared and Distinctive Neighborhoods of Emerin and Lamin B Receptor Revealed by Proximity Labeling and Quantitative Proteomics.
Cheng LC, Zhang X, Abhinav K, Nguyen JA, Baboo S, Martinez-Bartolome S, Branon TC, Ting AY, Loose E, Yates JR 3rd, Gerace L.
J Proteome Res. 2022 Sep 2;21(9):2197-2210. doi: 10.1021/acs.jproteome.2c00281. Epub 2022 Aug 16.
PubMed
Associated Plasmids |
| MicroRNA-223 Suppresses Human Hepatic Stellate Cell Activation Partly via Regulating the Actin Cytoskeleton and Alleviates Fibrosis in Organoid Models of Liver Injury. Ariyachet C, Chuaypen N, Kaewsapsak P, Chantaravisoot N, Jindatip D, Potikanond S, Tangkijvanich P. Int J Mol Sci. 2022 Aug 19;23(16):9380. doi: 10.3390/ijms23169380. PubMed |
| ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection. Ching KL, de Vries M, Gago J, Dancel-Manning K, Sall J, Rice WJ, Barnett C, Khodadadi-Jamayran A, Tsirigos A, Liang FX, Thorpe LE, Shopsin B, Segal LN, Dittmann M, Torres VJ, Cadwell K. PLoS Biol. 2022 Sep 13;20(9):e3001754. doi: 10.1371/journal.pbio.3001754. eCollection 2022 Sep. PubMed |
| Polarized NHE1 and SWELL1 regulate migration direction, efficiency and metastasis. Zhang Y, Li Y, Thompson KN, Stoletov K, Yuan Q, Bera K, Lee SJ, Zhao R, Kiepas A, Wang Y, Mistriotis P, Serra SA, Lewis JD, Valverde MA, Martin SS, Sun SX, Konstantopoulos K. Nat Commun. 2022 Oct 17;13(1):6128. doi: 10.1038/s41467-022-33683-1. PubMed |
| Instability of Mature ABCA3 Protein: Toward a New Classification of ABCA3 Mutations? Onnee M, Duriez B, Simon S, Szczepaniak C, Guguin A, Epaud R, Hamouda S, Fanen P, de Becdelievre A. Am J Respir Cell Mol Biol. 2022 Nov;67(5):602-605. doi: 10.1165/rcmb.2021-0430LE. PubMed |
| Extracellular fluid viscosity enhances cell migration and cancer dissemination. Bera K, Kiepas A, Godet I, Li Y, Mehta P, Ifemembi B, Paul CD, Sen A, Serra SA, Stoletov K, Tao J, Shatkin G, Lee SJ, Zhang Y, Boen A, Mistriotis P, Gilkes DM, Lewis JD, Fan CM, Feinberg AP, Valverde MA, Sun SX, Konstantopoulos K. Nature. 2022 Nov;611(7935):365-373. doi: 10.1038/s41586-022-05394-6. Epub 2022 Nov 2. PubMed |
| Hepatic PLIN5 Deficiency Impairs Lipogenesis through Mitochondrial Dysfunction. Zhang E. Int J Mol Sci. 2022 Dec 9;23(24):15598. doi: 10.3390/ijms232415598. PubMed |
| Evolution of nanobodies specific for BCL11A. Yin M, Izadi M, Tenglin K, Viennet T, Zhai L, Zheng G, Arthanari H, Dassama LMK, Orkin SH. Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2218959120. doi: 10.1073/pnas.2218959120. Epub 2023 Jan 10. PubMed |
| Cytokinesis machinery promotes cell dissociation from collectively migrating strands in confinement. Law RA, Kiepas A, Desta HE, Perez Ipina E, Parlani M, Lee SJ, Yankaskas CL, Zhao R, Mistriotis P, Wang N, Gu Z, Kalab P, Friedl P, Camley BA, Konstantopoulos K. Sci Adv. 2023 Jan 13;9(2):eabq6480. doi: 10.1126/sciadv.abq6480. Epub 2023 Jan 11. PubMed |
| FLI1 and FRA1 transcription factors drive the transcriptional regulatory networks characterizing muscle invasive bladder cancer. Guneri-Sozeri PY, Ozden-Yilmaz G, Kisim A, Cakiroglu E, Eray A, Uzuner H, Karakulah G, Pesen-Okvur D, Senturk S, Erkek-Ozhan S. Commun Biol. 2023 Feb 20;6(1):199. doi: 10.1038/s42003-023-04561-3. PubMed |
| Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination. Tsutsumi N, Hwang S, Waghray D, Hansen S, Jude KM, Wang N, Miao Y, Glassman CR, Caveney NA, Janda CY, Hannoush RN, Garcia KC. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2218238120. doi: 10.1073/pnas.2218238120. Epub 2023 Mar 9. PubMed |
| Redefining the role of AMPK in autophagy and the energy stress response. Park JM, Lee DH, Kim DH. Nat Commun. 2023 May 24;14(1):2994. doi: 10.1038/s41467-023-38401-z. PubMed |
| IFITM1 inhibits trophoblast invasion and is induced in placentas associated with IFN-mediated pregnancy diseases. Degrelle SA, Buchrieser J, Dupressoir A, Porrot F, Loeuillet L, Schwartz O, Fournier T. iScience. 2023 Jun 15;26(7):107147. doi: 10.1016/j.isci.2023.107147. eCollection 2023 Jul 21. PubMed |
| Oncometabolite D-2-hydroxyglutarate-dependent metabolic reprogramming induces skeletal muscle atrophy during cancer cachexia. Zhu X, Hao J, Zhang H, Chi M, Wang Y, Huang J, Xu R, Xincai Z, Xin B, Sun X, Zhang J, Zhou S, Cheng D, Yuan T, Ding J, Zheng S, Guo C, Yang Q. Commun Biol. 2023 Sep 23;6(1):977. doi: 10.1038/s42003-023-05366-0. PubMed |
| Functional classification of DDOST variants of uncertain clinical significance in congenital disorders of glycosylation. Kas SM, Mundra PA, Smith DL, Marais R. Sci Rep. 2023 Oct 17;13(1):17648. doi: 10.1038/s41598-023-42178-y. PubMed |
A PINK1 input threshold arises from positive feedback in the PINK1/Parkin mitophagy decision circuit.
Waters CS, Angenent SB, Altschuler SJ, Wu LF.
Cell Rep. 2023 Oct 31;42(10):113260. doi: 10.1016/j.celrep.2023.113260. Epub 2023 Oct 17.
PubMed
Associated Plasmids |
| Human cerebrospinal fluid affects chemoradiotherapy sensitivities in tumor cells from patients with glioblastoma. Stringer BW, De Silva MI, Greenberg Z, Norena Puerta A, Adams R, Milky B, Zabolocki M, van den Hurk M, Ebert LM, Fairly Bishop C, Conn SJ, Kichenadasse G, Michael MZ, Ormsby RJ, Poonoose S, Bardy C. Sci Adv. 2023 Oct 27;9(43):eadf1332. doi: 10.1126/sciadv.adf1332. Epub 2023 Oct 25. PubMed |
| LKB1 suppresses growth and promotes the internalization of EGFR through the PIKFYVE lipid kinase. Ferrarone JR, Thomas J, Unni AM, Zheng Y, Nagiec MJ, Gardner EE, Mashadova O, Li K, Koundouros N, Montalbano A, Mustafa M, Cantley LC, Blenis J, Sanjana NE, Varmus H. bioRxiv [Preprint]. 2023 Oct 20:2023.10.19.563158. doi: 10.1101/2023.10.19.563158. PubMed |
| Cytoplasmic accumulation and plasma membrane association of anillin and Ect2 promote confined migration and invasion. Tran AT, Wisniewski EO, Mistriotis P, Stoletov K, Parlani M, Amitrano A, Ifemembi B, Lee SJ, Bera K, Zhang Y, Tuntithavornwat S, Afthinos A, Kiepas A, Jamieson JJ, Zuo Y, Habib D, Wu PH, Martin SS, Gerecht S, Gu L, Lewis JD, Kalab P, Friedl P, Konstantopoulos K. Res Sq [Preprint]. 2024 Jan 10:rs.3.rs-3640969. doi: 10.21203/rs.3.rs-3640969/v1. PubMed |
| A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models. Puray-Chavez M, LaPak KM, Jasuja R, Pan J, Xu J, Eschbach JE, Mohammed S, Lawson DQ, Wang Q, Brody SL, Major MB, Goldfarb D, Kutluay SB. bioRxiv [Preprint]. 2024 Jan 8:2024.01.07.574522. doi: 10.1101/2024.01.07.574522. PubMed |
| Rab32 family proteins regulate autophagosomal components recycling. Wu Z, Que H, Li C, Yan L, Wang S, Rong Y. J Cell Biol. 2024 Mar 4;223(3):e202306040. doi: 10.1083/jcb.202306040. Epub 2024 Feb 7. PubMed |
| Neutralizing immunity against coronaviruses in Tanzanian health care workers. Barabona G, Ngare I, Kamori D, Nkinda L, Kosugi Y, Mawazo A, Ekwabi R, Kinasa G, Chuwa H, Sato K, Sunguya B, Ueno T. Sci Rep. 2024 Mar 6;14(1):5508. doi: 10.1038/s41598-024-55989-4. PubMed |
| Loss of tumor-derived SMAD4 enhances primary tumor growth but not metastasis following BMP4 signalling. Chi LH, Redfern AD, Roslan S, Street IP, Burrows AD, Anderson RL. Cell Commun Signal. 2024 Apr 30;22(1):248. doi: 10.1186/s12964-024-01559-0. PubMed |
| Polymorphic residues in HLA-B that mediate HIV control distinctly modulate peptide interactions with both TCR and KIR molecules. Tano-Menka R, Singh NK, Muzhingi I, Li X, Mandanas MV, Kaseke C, Crain CR, Zhang A, Ogunshola FJ, Vecchiarello L, Piechocka-Trocha A, Bashirova A, Birnbaum ME, Carrington M, Walker BD, Gaiha GD. Structure. 2024 May 7:S0969-2126(24)00141-2. doi: 10.1016/j.str.2024.04.015. PubMed |
| Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase. Ferrarone JR, Thomas J, Unni AM, Zheng Y, Nagiec MJ, Gardner EE, Mashadova O, Li K, Koundouros N, Montalbano A, Mustafa M, Cantley LC, Blenis J, Sanjana NE, Varmus H. Proc Natl Acad Sci U S A. 2024 May 21;121(21):e2403685121. doi: 10.1073/pnas.2403685121. Epub 2024 May 14. PubMed |
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