pAAV-CAG-FLuc Citations (10)
Originally described in: Using a barcoded AAV capsid library to select for clinically relevant gene therapy vectors.Pekrun K, De Alencastro G, Luo QJ, Liu J, Kim Y, Nygaard S, Galivo F, Zhang F, Song R, Tiffany MR, Xu J, Hebrok M, Grompe M, Kay MA JCI Insight. 2019 Nov 14;4(22). pii: 131610. doi: 10.1172/jci.insight.131610. PubMed Journal
Articles Citing pAAV-CAG-FLuc
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CRISPR based editing of SIV proviral DNA in ART treated non-human primates. Mancuso P, Chen C, Kaminski R, Gordon J, Liao S, Robinson JA, Smith MD, Liu H, Sariyer IK, Sariyer R, Peterson TA, Donadoni M, Williams JB, Siddiqui S, Bunnell BA, Ling B, MacLean AG, Burdo TH, Khalili K. Nat Commun. 2020 Nov 27;11(1):6065. doi: 10.1038/s41467-020-19821-7. PubMed |
High concordance of ELISA and neutralization assays allows for the detection of antibodies to individual AAV serotypes. Gardner MR, Mendes DE, Muniz CP, Martinez-Navio JM, Fuchs SP, Gao G, Desrosiers RC. Mol Ther Methods Clin Dev. 2022 Jan 7;24:199-206. doi: 10.1016/j.omtm.2022.01.003. eCollection 2022 Mar 10. PubMed |
Single-shot AAV-vectored vaccine against SARS-CoV-2 with fast and long-lasting immunity. Wu F, Luo S, Zhang Y, Hairui Wang Zhaofei Guo Chunting He Shuting Bai Penghui He Min Jiang Xiaoyan Chen, Guangsheng Du Xun Sun YO. Acta Pharm Sin B. 2022 Jul 12. doi: 10.1016/j.apsb.2022.07.004. PubMed |
Selection of rAAV vectors that cross the human blood-brain barrier and target the central nervous system using a transwell model. Song R, Pekrun K, Khan TA, Zhang F, Pasca SP, Kay MA. Mol Ther Methods Clin Dev. 2022 Sep 7;27:73-88. doi: 10.1016/j.omtm.2022.09.002. eCollection 2022 Dec 8. PubMed |
Aptamer-programmable adeno-associated viral vectors as a novel platform for cell-specific gene transfer. Puzzo F, Zhang C, Powell Gray B, Zhang F, Sullenger BA, Kay MA. Mol Ther Nucleic Acids. 2023 Jan 21;31:383-397. doi: 10.1016/j.omtn.2023.01.007. eCollection 2023 Mar 14. PubMed |
The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner.
Gonzalez-Sandoval A, Pekrun K, Tsuji S, Zhang F, Hung KL, Chang HY, Kay MA.
Nat Commun. 2023 Apr 28;14(1):2448. doi: 10.1038/s41467-023-38106-3.
PubMed
Associated Plasmids |
A strategy for high antibody expression with low anti-drug antibodies using AAV9 vectors. Davis-Gardner ME, Weber JA, Xie J, Pekrun K, Alexander EA, Weisgrau KL, Furlott JR, Rakasz EG, Kay MA, Gao G, Farzan M, Gardner MR. Front Immunol. 2023 Apr 21;14:1105617. doi: 10.3389/fimmu.2023.1105617. eCollection 2023. PubMed |
Selection of viral capsids and promoters affects the efficacy of rescue of Tmprss3-deficient cochlea. Aaron KA, Pekrun K, Atkinson PJ, Billings SE, Abitbol JM, Lee IA, Eltawil Y, Chen YS, Dong W, Nelson RF, Kay MA, Cheng AG. Mol Ther Methods Clin Dev. 2023 Aug 11;30:413-428. doi: 10.1016/j.omtm.2023.08.004. eCollection 2023 Sep 14. PubMed |
Human paraneoplastic antigen Ma2 (PNMA2) forms icosahedral capsids that can be engineered for mRNA delivery. Madigan V, Zhang Y, Raghavan R, Wilkinson ME, Faure G, Puccio E, Segel M, Lash B, Macrae RK, Zhang F. Proc Natl Acad Sci U S A. 2024 Mar 12;121(11):e2307812120. doi: 10.1073/pnas.2307812120. Epub 2024 Mar 4. PubMed |
Comprehensive mutagenesis maps the effect of all single-codon mutations in the AAV2 rep gene on AAV production. Jain NK, Ogden PJ, Church GM. Elife. 2024 Mar 27;12:RP87730. doi: 10.7554/eLife.87730. PubMed |
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