LentiCRISPRv2GFP Citations (74)
Originally described in: Systematic in vivo inactivation of chromatin regulating enzymes identifies Setd2 as a potent tumor suppressor in lung adenocarcinoma.Walter DM, Venancio OS, Buza EL, Tobias JW, Deshpande C, Gudiel AA, Kim-Kiselak C, Cicchini M, Yates TJ, Feldser DM Cancer Res. 2017 Feb 15. pii: canres.2159.2016. doi: 10.1158/0008-5472.CAN-16-2159. PubMed Journal
Articles Citing LentiCRISPRv2GFP
| Articles |
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Systematic in vivo inactivation of chromatin regulating enzymes identifies Setd2 as a potent tumor suppressor in lung adenocarcinoma.
Walter DM, Venancio OS, Buza EL, Tobias JW, Deshpande C, Gudiel AA, Kim-Kiselak C, Cicchini M, Yates TJ, Feldser DM.
Cancer Res. 2017 Feb 15. pii: canres.2159.2016. doi: 10.1158/0008-5472.CAN-16-2159.
PubMed
Associated Plasmids |
| Tissue-selective restriction of RNA editing of CaV1.3 by splicing factor SRSF9. Huang H, Kapeli K, Jin W, Wong YP, Arumugam TV, Koh JH, Srimasorn S, Mallilankaraman K, Chua JJE, Yeo GW, Soong TW. Nucleic Acids Res. 2018 Aug 21;46(14):7323-7338. doi: 10.1093/nar/gky348. PubMed |
| AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells. Pei S, Minhajuddin M, Adane B, Khan N, Stevens BM, Mack SC, Lai S, Rich JN, Inguva A, Shannon KM, Kim H, Tan AC, Myers JR, Ashton JM, Neff T, Pollyea DA, Smith CA, Jordan CT. Cell Stem Cell. 2018 Jul 5;23(1):86-100.e6. doi: 10.1016/j.stem.2018.05.021. Epub 2018 Jun 14. PubMed |
| Iron Homeostasis Determines Fate of Human Pluripotent Stem Cells Via Glycerophospholipids-Epigenetic Circuit. Han Z, Yu Y, Xu J, Bao Z, Xu Z, Hu J, Yu M, Bamba D, Ma W, Ding F, Zhang L, Jin M, Yan G, Huang Q, Wang X, Hua B, Yang F, Li Y, Lei L, Cao N, Pan Z, Cai B. Stem Cells. 2019 Apr;37(4):489-503. doi: 10.1002/stem.2967. Epub 2019 Jan 28. PubMed |
| Self-reactive CD4(+) IL-3(+) T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis. Anzai A, Mindur JE, Halle L, Sano S, Choi JL, He S, McAlpine CS, Chan CT, Kahles F, Valet C, Fenn AM, Nairz M, Rattik S, Iwamoto Y, Fairweather D, Walsh K, Libby P, Nahrendorf M, Swirski FK. J Exp Med. 2019 Feb 4;216(2):369-383. doi: 10.1084/jem.20180722. Epub 2019 Jan 22. PubMed |
| Magnesium-sensitive upstream ORF controls PRL phosphatase expression to mediate energy metabolism. Hardy S, Kostantin E, Wang SJ, Hristova T, Galicia-Vazquez G, Baranov PV, Pelletier J, Tremblay ML. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):2925-2934. doi: 10.1073/pnas.1815361116. Epub 2019 Feb 4. PubMed |
| Cutting Edge: Core Binding Factor beta Is Required for Group 2 Innate Lymphoid Cell Activation. Shen X, Liang M, Chen X, Pasha MA, D'Souza SS, Hidde K, Howard J, Sultana DA, Fung ITH, Ye L, Pan J, Liu G, Drake JR, Drake LA, Zhu J, Bhandoola A, Yang Q. J Immunol. 2019 Mar 15;202(6):1669-1673. doi: 10.4049/jimmunol.1800852. Epub 2019 Feb 6. PubMed |
| Loss of Sirtuin 1 Alters the Secretome of Breast Cancer Cells by Impairing Lysosomal Integrity. Latifkar A, Ling L, Hingorani A, Johansen E, Clement A, Zhang X, Hartman J, Fischbach C, Lin H, Cerione RA, Antonyak MA. Dev Cell. 2019 May 6;49(3):393-408.e7. doi: 10.1016/j.devcel.2019.03.011. Epub 2019 Apr 11. PubMed |
| Physical Principles of Membrane Shape Regulation by the Glycocalyx. Shurer CR, Kuo JC, Roberts LM, Gandhi JG, Colville MJ, Enoki TA, Pan H, Su J, Noble JM, Hollander MJ, O'Donnell JP, Yin R, Pedram K, Mockl L, Kourkoutis LF, Moerner WE, Bertozzi CR, Feigenson GW, Reesink HL, Paszek MJ. Cell. 2019 Jun 13;177(7):1757-1770.e21. doi: 10.1016/j.cell.2019.04.017. Epub 2019 May 2. PubMed |
| Compartmentalized effects of aging on group 2 innate lymphoid cell development and function. D'Souza SS, Shen X, Fung ITH, Ye L, Kuentzel M, Chittur SV, Furuya Y, Siebel CW, Maillard IP, Metzger DW, Yang Q. Aging Cell. 2019 Dec;18(6):e13019. doi: 10.1111/acel.13019. Epub 2019 Aug 20. PubMed |
| NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8(+) T Cells. Gupta SS, Sharp R, Hofferek C, Kuai L, Dorn GW 2nd, Wang J, Chen M. Cell Rep. 2019 Nov 12;29(7):1862-1877.e7. doi: 10.1016/j.celrep.2019.10.032. PubMed |
| The PAX-SIX-EYA-DACH network modulates GATA-FOG function in fly hematopoiesis and human erythropoiesis. Creed TM, Baldeosingh R, Eberly CL, Schlee CS, Kim M, Cutler JA, Pandey A, Civin CI, Fossett NG, Kingsbury TJ. Development. 2020 Jan 3;147(1). pii: dev.177022. doi: 10.1242/dev.177022. PubMed |
| Activation of group 2 innate lymphoid cells alleviates aging-associated cognitive decline. Fung ITH, Sankar P, Zhang Y, Robison LS, Zhao X, D'Souza SS, Salinero AE, Wang Y, Qian J, Kuentzel ML, Chittur SV, Temple S, Zuloaga KL, Yang Q. J Exp Med. 2020 Apr 6;217(4). pii: 133697. doi: 10.1084/jem.20190915. PubMed |
| Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development. Jacques S, van der Sloot AM, C Huard C, Coulombe-Huntington J, Tsao S, Tollis S, Bertomeu T, Culp EJ, Pallant D, Cook MA, Bonneil E, Thibault P, Wright GD, Tyers M. Genetics. 2020 Apr;214(4):1103-1120. doi: 10.1534/genetics.119.302851. Epub 2020 Feb 24. PubMed |
| Cerebral organoid and mouse models reveal a RAB39b-PI3K-mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes. Zhang W, Ma L, Yang M, Shao Q, Xu J, Lu Z, Zhao Z, Chen R, Chai Y, Chen JF. Genes Dev. 2020 Apr 1;34(7-8):580-597. doi: 10.1101/gad.332494.119. Epub 2020 Feb 27. PubMed |
| Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas. Fortin J, Tian R, Zarrabi I, Hill G, Williams E, Sanchez-Duffhues G, Thorikay M, Ramachandran P, Siddaway R, Wong JF, Wu A, Apuzzo LN, Haight J, You-Ten A, Snow BE, Wakeham A, Goldhamer DJ, Schramek D, Bullock AN, Dijke PT, Hawkins C, Mak TW. Cancer Cell. 2020 Mar 16;37(3):308-323.e12. doi: 10.1016/j.ccell.2020.02.002. Epub 2020 Mar 5. PubMed |
| Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells. Drainas AP, Lambuta RA, Ivanova I, Sercin O, Sarropoulos I, Smith ML, Efthymiopoulos T, Raeder B, Stutz AM, Waszak SM, Mardin BR, Korbel JO. Cell Rep. 2020 Apr 7;31(1):107465. doi: 10.1016/j.celrep.2020.03.029. PubMed |
| Edition of Prostaglandin E2 Receptors EP2 and EP4 by CRISPR/Cas9 Technology in Equine Adipose Mesenchymal Stem Cells. Mancanares ACF, Cabezas J, Manriquez J, de Oliveira VC, Wong Alvaro YS, Rojas D, Navarrete Aguirre F, Rodriguez-Alvarez L, Castro FO. Animals (Basel). 2020 Jun 23;10(6). pii: ani10061078. doi: 10.3390/ani10061078. PubMed |
| Fine-mapping within eQTL credible intervals by expression CROP-seq. Pan Y, Tian R, Lee C, Bao G, Gibson G. Biol Methods Protoc. 2020 Mar 28;5(1):bpaa008. doi: 10.1093/biomethods/bpaa008. eCollection 2020. PubMed |
| Rational discovery of molecular glue degraders via scalable chemical profiling. Mayor-Ruiz C, Bauer S, Brand M, Kozicka Z, Siklos M, Imrichova H, Kaltheuner IH, Hahn E, Seiler K, Koren A, Petzold G, Fellner M, Bock C, Muller AC, Zuber J, Geyer M, Thoma NH, Kubicek S, Winter GE. Nat Chem Biol. 2020 Nov;16(11):1199-1207. doi: 10.1038/s41589-020-0594-x. Epub 2020 Aug 3. PubMed |
| Tumor-Derived IL33 Promotes Tissue-Resident CD8(+) T Cells and Is Required for Checkpoint Blockade Tumor Immunotherapy. Chen L, Sun R, Xu J, Zhai W, Zhang D, Yang M, Yue C, Chen Y, Li S, Turnquist H, Jiang J, Lu B. Cancer Immunol Res. 2020 Nov;8(11):1381-1392. doi: 10.1158/2326-6066.CIR-19-1024. Epub 2020 Sep 11. PubMed |
| Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing. Suh S, Choi EH, Leinonen H, Foik AT, Newby GA, Yeh WH, Dong Z, Kiser PD, Lyon DC, Liu DR, Palczewski K. Nat Biomed Eng. 2021 Feb;5(2):169-178. doi: 10.1038/s41551-020-00632-6. Epub 2020 Oct 19. PubMed |
| Necessity for Validation of Effectiveness of Selected Guide RNA In Silico for Application of CRISPR/Cas9. Kim DH, Lee J, Suh Y, Lee K. Mol Biotechnol. 2021 Feb;63(2):140-149. doi: 10.1007/s12033-020-00290-8. Epub 2021 Jan 2. PubMed |
| Glycogen metabolism is dispensable for tumour progression in clear cell renal cell carcinoma. Xie H, Song J, Godfrey J, Riscal R, Skuli N, Nissim I, Simon MC. Nat Metab. 2021 Mar;3(3):327-336. doi: 10.1038/s42255-021-00367-x. Epub 2021 Mar 23. PubMed |
| Antibody-mediated depletion of CCR10+EphA3+ cells ameliorates fibrosis in IPF. Hohmann MS, Habiel DM, Espindola MS, Huang G, Jones I, Narayanan R, Coelho AL, Oldham JM, Noth I, Ma SF, Kurkciyan A, McQualter JL, Carraro G, Stripp B, Chen P, Jiang D, Noble PW, Parks W, Woronicz J, Yarranton G, Murray LA, Hogaboam CM. JCI Insight. 2021 Jun 8;6(11). pii: 141061. doi: 10.1172/jci.insight.141061. PubMed |
| Immune modulatory effects of Idelalisib in stromal cells of chronic lymphocytic leukemia. Handl S, von Heydebrand F, Voelkl S, Oostendorp RAJ, Wilke J, Kremer AN, Mackensen A, Lutzny-Geier G. Leuk Lymphoma. 2021 May 17:1-11. doi: 10.1080/10428194.2021.1927019. PubMed |
| Core binding factor leukemia hijacks T-cell prone PU.1 antisense promoter. van der Kouwe E, Heller G, Czibere A, Pulikkan JA, Agreiter C, Castilla LH, Delwel R, Di Ruscio A, Ebralidze AK, Forte M, Grebien F, Heyes E, Kazianka L, Klinger J, Kornauth C, Le T, Lind K, Barbosa IAM, Pemovska T, Pichler AS, Schmolke AS, Schweicker CM, Sill H, Sperr WR, Spittler A, Surapally S, Trinh BQ, Valent P, Vanura K, Welner RS, Zuber J, Tenen DG, Staber PB. Blood. 2021 May 19. pii: S0006-4971(21)01066-1. doi: 10.1182/blood.2020008971. PubMed |
| Coupled analysis of transcriptome and BCR mutations reveals role of OXPHOS in affinity maturation. Chen D, Wang Y, Manakkat Vijay GK, Fu S, Nash CW, Xu D, He D, Salomonis N, Singh H, Xu H. Nat Immunol. 2021 Jul;22(7):904-913. doi: 10.1038/s41590-021-00936-y. Epub 2021 May 24. PubMed |
| The Cancer Therapy-Related Clonal Hematopoiesis Driver Gene Ppm1d Promotes Inflammation and Non-Ischemic Heart Failure in Mice. Yura Y, Miura-Yura E, Katanasaka Y, Min KD, Chavkin N, Polizio AH, Ogawa H, Horitani K, Doviak H, Evans MA, Sano M, Wang Y, Boroviak K, Philippos G, Domingues AF, Vassiliou G, Sano S, Walsh K. Circ Res. 2021 Sep 3;129(6):684-698. doi: 10.1161/CIRCRESAHA.121.319314. Epub 2021 Jul 28. PubMed |
| Histone H2A.X phosphorylation and Caspase-Initiated Chromatin Condensation in late-stage erythropoiesis. Jeffery NN, Davidson C, Peslak SA, Kingsley PD, Nakamura Y, Palis J, Bulger M. Epigenetics Chromatin. 2021 Jul 30;14(1):37. doi: 10.1186/s13072-021-00408-5. PubMed |
| Allele-specific knockdown of mutant HTT protein via editing at coding region SNP heterozygosities. Oikemus SR, Pfister E, Sapp E, Chase KO, Kennington LA, Hudgens E, Miller R, Zhu LJ, Chaudhary A, Mick EO, Sena-Esteves M, Wolfe SA, DiFiglia M, Aronin N, Brodsky MH. Hum Gene Ther. 2021 Aug 10. doi: 10.1089/hum.2020.323. PubMed |
| Placenta-derived interferon-stimulated gene 20 controls ZIKA virus infection. Ding J, Aldo P, Roberts CM, Stabach P, Liu H, You Y, Qiu X, Jeong J, Maxwell A, Lindenbach B, Braddock D, Liao A, Mor G. EMBO Rep. 2021 Oct 5;22(10):e52450. doi: 10.15252/embr.202152450. Epub 2021 Aug 18. PubMed |
| Oxidized Phospholipids and Neutrophil Elastase Coordinately Play Critical Roles in NET Formation. Tokuhiro T, Ishikawa A, Sato H, Takita S, Yoshikawa A, Anzai R, Sato S, Aoyagi R, Arita M, Shibuya T, Aratani Y, Shimizu S, Tanaka M, Yotsumoto S. Front Cell Dev Biol. 2021 Sep 9;9:718586. doi: 10.3389/fcell.2021.718586. eCollection 2021. PubMed |
| Specific Activation of the CD271 Intracellular Domain in Combination with Chemotherapy or Targeted Therapy Inhibits Melanoma Progression. Saltari A, Dzung A, Quadri M, Tiso N, Facchinello N, Hernandez-Barranco A, Garcia-Silva S, Nogues L, Stoffel CI, Cheng PF, Turko P, Eichhoff OM, Truzzi F, Marconi A, Pincelli C, Peinado H, Dummer R, Levesque MP. Cancer Res. 2021 Dec 1;81(23):6044-6057. doi: 10.1158/0008-5472.CAN-21-0117. Epub 2021 Oct 13. PubMed |
| CRISPR/Cas9 genome editing reveals an essential role for basigin in maintaining a nonkeratinized squamous epithelium in cornea. Woodward AM, Feeley MN, Rinaldi J, Argueso P. FASEB Bioadv. 2021 Aug 30;3(11):897-908. doi: 10.1096/fba.2021-00067. eCollection 2021 Nov. PubMed |
A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation.
Smith CE, Tsai YC, Liang YH, Khago D, Mariano J, Li J, Tarasov SG, Gergel E, Tsai B, Villaneuva M, Clapp ME, Magidson V, Chari R, Byrd RA, Ji X, Weissman AM.
PLoS Biol. 2021 Dec 8;19(12):e3001474. doi: 10.1371/journal.pbio.3001474. eCollection 2021 Dec.
PubMed
Associated Plasmids |
| Targeted core-shell nanoparticles for precise CTCF gene insert in treatment of metastatic breast cancer. Duan J, Bao C, Xie Y, Guo H, Liu Y, Li J, Liu R, Li P, Bai J, Yan Y, Mu L, Li X, Wang G, Lu W. Bioact Mater. 2021 Oct 7;11:1-14. doi: 10.1016/j.bioactmat.2021.10.007. eCollection 2022 May. PubMed |
| Differential antigenic requirements by diverse MR1-restricted T cells. Seneviratna R, Redmond SJ, McWilliam HE, Reantragoon R, Villadangos JA, McCluskey J, Godfrey DI, Gherardin NA. Immunol Cell Biol. 2022 Feb;100(2):112-126. doi: 10.1111/imcb.12519. Epub 2022 Jan 13. PubMed |
| Selective suppression of IL-10 transcription by calcineurin in dendritic cells through inactivation of CREB. Lu X, Oh-Hora M, Takeda K, Yamasaki S. Int Immunol. 2022 Mar 25;34(4):197-206. doi: 10.1093/intimm/dxab112. PubMed |
| Identification of a STIM1 Splicing Variant that Promotes Glioblastoma Growth. Xie J, Ma G, Zhou L, He L, Zhang Z, Tan P, Huang Z, Fang S, Wang T, Lee YT, Wen S, Siwko S, Wang L, Liu J, Du Y, Zhang N, Liu X, Han L, Huang Y, Wang R, Wang Y, Zhou Y, Han W. Adv Sci (Weinh). 2022 Apr;9(11):e2103940. doi: 10.1002/advs.202103940. Epub 2022 Jan 25. PubMed |
| Genome-wide CRISPR/Cas9 screening identifies determinant of panobinostat sensitivity in acute lymphoblastic leukemia. Jiang C, Qian M, Gocho Y, Yang W, Du G, Shen S, Yang JJ, Zhang H. Blood Adv. 2022 Apr 26;6(8):2496-2509. doi: 10.1182/bloodadvances.2021006152. PubMed |
| Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer. Sela Y, Li J, Maheswaran S, Norgard R, Yuan S, Hubbi M, Doepner M, Xu JP, Ho ES, Mesaros C, Sheehan C, Croley G, Muir A, Blair IA, Shalem O, Dang CV, Stanger BZ. Cancer Res. 2022 May 16;82(10):1890-1908. doi: 10.1158/0008-5472.CAN-22-0431. PubMed |
| Expression of Constitutive Fusion of Ubiquitin to PCNA Restores the Level of Immunoglobulin A/T Mutations During Somatic Hypermutation in the Ramos Cell Line. Lerner LK, Bonte D, Le Guillou M, Mohammad MM, Kasraian Z, Sarasin A, Despras E, Aoufouchi S. Front Immunol. 2022 Apr 1;13:871766. doi: 10.3389/fimmu.2022.871766. eCollection 2022. PubMed |
| Retinol Binding Protein 7 Promotes Adipogenesis in vitro and Regulates Expression of Genes Involved in Retinol Metabolism. Kim DH, Ahn J, Suh Y, Ziouzenkova O, Lee JW, Lee K. Front Cell Dev Biol. 2022 Apr 14;10:876031. doi: 10.3389/fcell.2022.876031. eCollection 2022. PubMed |
| Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme. Jacquemin G, Wurmser A, Huyghe M, Sun W, Homayed Z, Merle C, Perkins M, Qasrawi F, Richon S, Dingli F, Arras G, Loew D, Vignjevic D, Pannequin J, Fre S. Elife. 2022 May 11;11. pii: 76541. doi: 10.7554/eLife.76541. PubMed |
| FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits. Tsai JW, Cejas P, Wang DK, Patel S, Wu DW, Arounleut P, Wei X, Zhou N, Syamala S, Dubois FPB, Crane A, Pelton K, Vogelzang J, Sousa C, Baguette A, Chen X, Condurat AL, Dixon-Clarke SE, Zhou KN, Lu SD, Gonzalez EM, Chacon MS, Digiacomo JJ, Kumbhani R, Novikov D, Hunter J, Tsoli M, Ziegler DS, Dirksen U, Jager N, Balasubramanian GP, Kramm CM, Nathrath M, Bielack S, Baker SJ, Zhang J, McFarland JM, Getz G, Aguet F, Jabado N, Witt O, Pfister SM, Ligon KL, Hovestadt V, Kleinman CL, Long H, Jones DTW, Bandopadhayay P, Phoenix TN. Cancer Res. 2022 Sep 2;82(17):2980-3001. doi: 10.1158/0008-5472.CAN-22-0671. PubMed |
| Generating Custom Pooled CRISPR Libraries for Genetic Dissection of Biological Pathways. Gulbranson DR. Methods Mol Biol. 2022;2473:333-347. doi: 10.1007/978-1-0716-2209-4_21. PubMed |
| S146L in MYC is a context-dependent activating substitution in cancer development. Hinds JW, Feris EJ, Wilkins OM, Deary LT, Wang X, Cole MD. PLoS One. 2022 Aug 26;17(8):e0272771. doi: 10.1371/journal.pone.0272771. eCollection 2022. PubMed |
| Ectopic JAK-STAT activation enables the transition to a stem-like and multilineage state conferring AR-targeted therapy resistance. Deng S, Wang C, Wang Y, Xu Y, Li X, Johnson NA, Mukherji A, Lo UG, Xu L, Gonzalez J, Metang LA, Ye J, Tirado CR, Rodarte K, Zhou Y, Xie Z, Arana C, Annamalai V, Liu X, Vander Griend DJ, Strand D, Hsieh JT, Li B, Raj G, Wang T, Mu P. Nat Cancer. 2022 Sep;3(9):1071-1087. doi: 10.1038/s43018-022-00431-9. Epub 2022 Sep 5. PubMed |
| Bifunctional cancer cell-based vaccine concomitantly drives direct tumor killing and antitumor immunity. Chen KS, Reinshagen C, Van Schaik TA, Rossignoli F, Borges P, Mendonca NC, Abdi R, Simon B, Reardon DA, Wakimoto H, Shah K. Sci Transl Med. 2023 Jan 4;15(677):eabo4778. doi: 10.1126/scitranslmed.abo4778. Epub 2023 Jan 4. PubMed |
| MLL3 loss drives metastasis by promoting a hybrid epithelial-mesenchymal transition state. Cui J, Zhang C, Lee JE, Bartholdy BA, Yang D, Liu Y, Erler P, Galbo PM Jr, Hodge DQ, Huangfu D, Zheng D, Ge K, Guo W. Nat Cell Biol. 2023 Jan;25(1):145-158. doi: 10.1038/s41556-022-01045-0. Epub 2023 Jan 5. PubMed |
| A NPAS4-NuA4 complex couples synaptic activity to DNA repair. Pollina EA, Gilliam DT, Landau AT, Lin C, Pajarillo N, Davis CP, Harmin DA, Yap EL, Vogel IR, Griffith EC, Nagy MA, Ling E, Duffy EE, Sabatini BL, Weitz CJ, Greenberg ME. Nature. 2023 Feb;614(7949):732-741. doi: 10.1038/s41586-023-05711-7. Epub 2023 Feb 15. PubMed |
| The Hdc GC box is critical for Hdc gene transcription and histamine-mediated anaphylaxis. Li Y, Gao J, Zhao D, Guan X, Morris SC, Finkelman FD, Huang H. J Allergy Clin Immunol. 2023 Jul;152(1):195-204.e3. doi: 10.1016/j.jaci.2023.01.031. Epub 2023 Feb 18. PubMed |
| Alpha1A- and Beta3-Adrenoceptors Interplay in Adipose Multipotent Mesenchymal Stromal Cells: A Novel Mechanism of Obesity-Driven Hypertension. Chechekhin V, Ivanova A, Kulebyakin K, Sysoeva V, Naida D, Arbatsky M, Basalova N, Karagyaur M, Skryabina M, Efimenko A, Grigorieva O, Kalinina N, Tkachuk V, Tyurin-Kuzmin P. Cells. 2023 Feb 11;12(4):585. doi: 10.3390/cells12040585. PubMed |
| TCF12 Deficiency Impairs the Proliferation of Glioblastoma Tumor Cells and Improves Survival. Pang Y, Zhou S, Zumbo P, Betel D, Cisse B. Cancers (Basel). 2023 Mar 29;15(7):2033. doi: 10.3390/cancers15072033. PubMed |
| Twist1-IRF9 Interaction Is Necessary for IFN-Stimulated Gene Anti-Zika Viral Infection. You Y, Grasso E, Alvero A, Condon J, Dimova T, Hu A, Ding J, Alexandrova M, Manchorova D, Dimitrova V, Liao A, Mor G. J Immunol. 2023 May 5:ji2300081. doi: 10.4049/jimmunol.2300081. PubMed |
| Deep sampling of gRNA in the human genome and deep-learning-informed prediction of gRNA activities. Zhang H, Yan J, Lu Z, Zhou Y, Zhang Q, Cui T, Li Y, Chen H, Ma L. Cell Discov. 2023 May 16;9(1):48. doi: 10.1038/s41421-023-00549-9. PubMed |
| Combined loss of CDH1 and downstream regulatory sequences drive early-onset diffuse gastric cancer and increase penetrance of hereditary diffuse gastric cancer. Sao Jose C, Garcia-Pelaez J, Ferreira M, Arrieta O, Andre A, Martins N, Solis S, Martinez-Benitez B, Ordonez-Sanchez ML, Rodriguez-Torres M, Sommer AK, Te Paske IBAW, Caldas C, Tischkowitz M, Tusie MT, Hoogerbrugge N, Demidov G, de Voer RM, Laurie S, Oliveira C. Gastric Cancer. 2023 Sep;26(5):653-666. doi: 10.1007/s10120-023-01395-0. Epub 2023 May 30. PubMed |
| Gene-edited and -engineered stem cell platform drives immunotherapy for brain metastatic melanomas. Kanaya N, Kitamura Y, Lopez Vazquez M, Franco A, Chen KS, van Schaik TA, Farzani TA, Borges P, Ichinose T, Seddiq W, Kuroda S, Boland G, Jahan N, Fisher D, Wakimoto H, Shah K. Sci Transl Med. 2023 May 31;15(698):eade8732. doi: 10.1126/scitranslmed.ade8732. Epub 2023 May 31. PubMed |
| Stromal-induced epithelial-mesenchymal transition induces targetable drug resistance in acute lymphoblastic leukemia. Park CS, Yoshihara H, Gao Q, Qu C, Iacobucci I, Ghate PS, Connelly JP, Pruett-Miller SM, Wagner B, Robinson CG, Mishra A, Peng J, Yang L, Rankovic Z, Finkelstein D, Luger S, Litzow M, Paietta EM, Hebbar N, Velasquez MP, Mullighan CG. Cell Rep. 2023 Jul 25;42(7):112804. doi: 10.1016/j.celrep.2023.112804. Epub 2023 Jul 14. PubMed |
| Efficient delivery of a large-size Cas9-EGFP vector in porcine fetal fibroblasts using a Lonza 4D-Nucleofector system. Liu W, Wang X, Liu R, Liao Y, Peng Z, Jiang H, Jing Q, Xing Y. BMC Biotechnol. 2023 Aug 16;23(1):29. doi: 10.1186/s12896-023-00799-1. PubMed |
| Targeted inhibition of protein synthesis renders cancer cells vulnerable to apoptosis by unfolded protein response. Gsottberger F, Meier C, Ammon A, Parker S, Wendland K, George R, Petkovic S, Mellenthin L, Emmerich C, Lutzny-Geier G, Metzler M, Mackensen A, Chandramohan V, Muller F. Cell Death Dis. 2023 Aug 26;14(8):561. doi: 10.1038/s41419-023-06055-w. PubMed |
| DHODH: a promising target in the treatment of T-cell acute lymphoblastic leukemia. Sexauer AN, Alexe G, Gustafsson K, Zanetakos E, Milosevic J, Ayres M, Gandhi V, Pikman Y, Stegmaier K, Sykes DB. Blood Adv. 2023 Nov 14;7(21):6685-6701. doi: 10.1182/bloodadvances.2023010337. PubMed |
| Advances and Obstacles in Using CRISPR/Cas9 Technology for Non-Coding RNA Gene Knockout in Human Mesenchymal Stromal Cells. Basalova N, Illarionova M, Skryabina M, Vigovskiy M, Tolstoluzhinskaya A, Primak A, Chechekhina E, Chechekhin V, Karagyaur M, Efimenko A. Noncoding RNA. 2023 Aug 24;9(5):49. doi: 10.3390/ncrna9050049. PubMed |
| CRISPR/Cas9-Mediated Generation of COL7A1-Deficient Keratinocyte Model of Recessive Dystrophic Epidermolysis Bullosa. Alipour F, Ahmadraji M, Yektadoost E, Mohammadi P, Baharvand H, Basiri M. Cell J. 2023 Oct 9;25(10):665-673. doi: 10.22074/cellj.2023.1989321.1225. PubMed |
| BRD4 binds to active cranial neural crest enhancers to regulate RUNX2 activity during osteoblast differentiation. Musa RE, Lester KL, Quickstad G, Vardabasso S, Shumate TV, Salcido RT, Ge K, Shpargel KB. Development. 2024 Jan 15;151(2):dev202110. doi: 10.1242/dev.202110. Epub 2024 Jan 24. PubMed |
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