pLentiCRISPR-E Citations (17)
Originally described in: Differential effects of clinically-relevant N- vs C-terminal truncating CDKN1A mutations on cisplatin sensitivity in bladder cancer.Sikder RK, Ellithi M, Uzzo RN, Weader D, Metz AL, Behbahani A, McKenzie ER, El-Deiry WS, Abbosh PH Mol Cancer Res. 2020 Dec 3. pii: 1541-7786.MCR-19-1200. doi: 10.1158/1541-7786.MCR-19-1200. PubMed Journal
Articles Citing pLentiCRISPR-E
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| Role of Dopamine Receptors in the Anticancer Activity of ONC201. Kline CLB, Ralff MD, Lulla AR, Wagner JM, Abbosh PH, Dicker DT, Allen JE, El-Deiry WS. Neoplasia. 2018 Jan;20(1):80-91. doi: 10.1016/j.neo.2017.10.002. Epub 2017 Dec 5. PubMed |
| B7-H3 specific T cells with chimeric antigen receptor and decoy PD-1 receptors eradicate established solid human tumors in mouse models. Huang B, Luo L, Wang J, He B, Feng R, Xian N, Zhang Q, Chen L, Huang G. Oncoimmunology. 2019 Nov 4;9(1):1684127. doi: 10.1080/2162402X.2019.1684127. eCollection 2020. PubMed |
| Targeting Mutant PPM1D Sensitizes Diffuse Intrinsic Pontine Glioma Cells to the PARP Inhibitor Olaparib. Wang Z, Xu C, Diplas BH, Moure CJ, Chen CJ, Chen LH, Du C, Zhu H, Greer PK, Zhang L, He Y, Waitkus MS, Yan H. Mol Cancer Res. 2020 Jul;18(7):968-980. doi: 10.1158/1541-7786.MCR-19-0507. Epub 2020 Mar 30. PubMed |
| Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity. Zhou C, Chen X, Planells-Cases R, Chu J, Wang L, Cao L, Li Z, Lopez-Cayuqueo KI, Xie Y, Ye S, Wang X, Ullrich F, Ma S, Fang Y, Zhang X, Qian Z, Liang X, Cai SQ, Jiang Z, Zhou D, Leng Q, Xiao TS, Lan K, Yang J, Li H, Peng C, Qiu Z, Jentsch TJ, Xiao H. Immunity. 2020 May 19;52(5):767-781.e6. doi: 10.1016/j.immuni.2020.03.016. Epub 2020 Apr 10. PubMed |
| Hypoxia-induced TGF-beta-RBFOX2-ESRP1 axis regulates human MENA alternative splicing and promotes EMT in breast cancer. Ahuja N, Ashok C, Natua S, Pant D, Cherian A, Pandkar MR, Yadav P, Vishnu NSS, Mishra J, Samaiya A, Shukla S. NAR Cancer. 2020 Sep 18;2(3):zcaa021. doi: 10.1093/narcan/zcaa021. eCollection 2020 Sep. PubMed |
| P53-independent partial restoration of the p53 pathway in tumors with mutated p53 through ATF4 transcriptional modulation by ERK1/2 and CDK9. Tian X, Ahsan N, Lulla A, Lev A, Abbosh P, Dicker DT, Zhang S, El-Deiry WS. Neoplasia. 2021 Feb 11;23(3):304-325. doi: 10.1016/j.neo.2021.01.004. PubMed |
| E2F1 and epigenetic modifiers orchestrate breast cancer progression by regulating oxygen-dependent ESRP1 expression. Ashok C, Ahuja N, Natua S, Mishra J, Samaiya A, Shukla S. Oncogenesis. 2021 Aug 6;10(8):58. doi: 10.1038/s41389-021-00347-6. PubMed |
| Deconvoluting Mechanisms of Acquired Resistance to RAF Inhibitors in BRAF(V600E)-Mutant Human Glioma. Schreck KC, Morin A, Zhao G, Allen AN, Flannery P, Glantz M, Green AL, Jones C, Jones KL, Kilburn LB, Nazemi KJ, Samuel D, Sanford B, Solomon DA, Wang J, Pratilas CA, Nicolaides T, Mulcahy Levy JM. Clin Cancer Res. 2021 Nov 15;27(22):6197-6208. doi: 10.1158/1078-0432.CCR-21-2660. Epub 2021 Aug 25. PubMed |
| Human Cytomegalovirus Hijacks WD Repeat Domain 11 for Virion Assembly Compartment Formation and Virion Morphogenesis. Yang B, Yao Y, Cheng H, Wang XZ, Zhou YP, Huang SN, Ma X, Yang H, Wu J, Jiang X, Cheng S, Sun JY, Zeng WB, Chen J, Zhang FK, Shen HJ, Gu JY, McVoy MA, Britt WJ, Gong S, Luo MH. J Virol. 2022 Mar 9;96(5):e0182721. doi: 10.1128/JVI.01827-21. Epub 2022 Jan 12. PubMed |
| MTAP loss correlates with an immunosuppressive profile in GBM and its substrate MTA stimulates alternative macrophage polarization. Hansen LJ, Yang R, Roso K, Wang W, Chen L, Yang Q, Pirozzi CJ, He Y. Sci Rep. 2022 Mar 9;12(1):4183. doi: 10.1038/s41598-022-07697-0. PubMed |
Improved loss-of-function CRISPR-Cas9 genome editing in human cells concomitant with inhibition of TGF-beta signaling.
Mishra T, Bhardwaj V, Ahuja N, Gadgil P, Ramdas P, Shukla S, Chande A.
Mol Ther Nucleic Acids. 2022 Mar 8;28:202-218. doi: 10.1016/j.omtn.2022.03.003. eCollection 2022 Jun 14.
PubMed
Associated Plasmids |
| Genome-wide CRISPR screen identified a role for commander complex mediated ITGB1 recycling in basal insulin secretion. Yang L, Fye MA, Yang B, Tang Z, Zhang Y, Haigh S, Covington BA, Bracey K, Taraska JW, Kaverina I, Qu S, Chen W. Mol Metab. 2022 Sep;63:101541. doi: 10.1016/j.molmet.2022.101541. Epub 2022 Jul 11. PubMed |
| MORC3 restricts human cytomegalovirus infection by suppressing the major immediate-early promoter activity. Ma XH, Yao YX, Wang XZ, Zhou YP, Huang SN, Li D, Mei MJ, Wu JP, Pan YT, Cheng S, Jiang X, Sun JY, Zeng WB, Gong S, Cheng H, Luo MH, Yang B. J Med Virol. 2022 Nov;94(11):5492-5506. doi: 10.1002/jmv.28025. Epub 2022 Aug 5. PubMed |
| Deficiency of the Polycomb Protein RYBP and TET Methylcytosine Oxidases Promotes Extensive CpG Island Hypermethylation and Malignant Transformation. Cui W, Huang Z, Jin SG, Johnson J, Lau KH, Hostetter G, Pfeifer GP. Cancer Res. 2023 Aug 1;83(15):2480-2495. doi: 10.1158/0008-5472.CAN-23-0269. PubMed |
| PKM2 dictates the poised chromatin state of PFKFB3 promoter to enhance breast cancer progression. Pandkar MR, Raveendran A, Biswas K, Mutnuru SA, Mishra J, Samaiya A, Malys T, Mitrophanov AY, Sharan SK, Shukla S. NAR Cancer. 2023 Jun 28;5(3):zcad032. doi: 10.1093/narcan/zcad032. eCollection 2023 Sep. PubMed |
| Generation of a Well-Characterized Homozygous Chromodomain-Helicase-DNA-Binding Protein 4(G1003D) Mutant hESC Line Using CRISPR/eCas9 (ULIEGEe001-A-1). Chohra I, Giri S, Malgrange B. Int J Mol Sci. 2023 Jun 23;24(13):10543. doi: 10.3390/ijms241310543. PubMed |
| The RNA-binding protein LRPPRC promotes resistance to CDK4/6 inhibition in lung cancer. Zhou W, Wang W, Liang Y, Jiang R, Qiu F, Shao X, Liu Y, Fang L, Ni M, Yu C, Zhao Y, Huang W, Li J, Donovan MJ, Wang L, Ni J, Wang D, Fu T, Feng J, Wang X, Tan W, Fang X. Nat Commun. 2023 Jul 14;14(1):4212. doi: 10.1038/s41467-023-39854-y. PubMed |
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