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pU6-(BbsI)_CBh-Cas9-T2A-mCherry Citations (76)

Originally described in: Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.
Chu VT, Weber T, Wefers B, Wurst W, Sander S, Rajewsky K, Kuhn R Nat Biotechnol. 2015 Mar 24. doi: 10.1038/nbt.3198.
PubMed Journal

Articles Citing pU6-(BbsI)_CBh-Cas9-T2A-mCherry

Articles
Modeling Psychomotor Retardation using iPSCs from MCT8-Deficient Patients Indicates a Prominent Role for the Blood-Brain Barrier. Vatine GD, Al-Ahmad A, Barriga BK, Svendsen S, Salim A, Garcia L, Garcia VJ, Ho R, Yucer N, Qian T, Lim RG, Wu J, Thompson LM, Spivia WR, Chen Z, Van Eyk J, Palecek SP, Refetoff S, Shusta EV, Svendsen CN. Cell Stem Cell. 2017 Jun 1;20(6):831-843.e5. doi: 10.1016/j.stem.2017.04.002. Epub 2017 May 16. PubMed
Nuclear Envelope Rupture Is Enhanced by Loss of p53 or Rb. Yang Z, Maciejowski J, de Lange T. Mol Cancer Res. 2017 Nov;15(11):1579-1586. doi: 10.1158/1541-7786.MCR-17-0084. Epub 2017 Aug 15. PubMed
Sodium Channel beta2 Subunits Prevent Action Potential Propagation Failures at Axonal Branch Points. Cho IH, Panzera LC, Chin M, Hoppa MB. J Neurosci. 2017 Sep 27;37(39):9519-9533. doi: 10.1523/JNEUROSCI.0891-17.2017. Epub 2017 Sep 4. PubMed
Widespread activation of antisense transcription of the host genome during herpes simplex virus 1 infection. Wyler E, Menegatti J, Franke V, Kocks C, Boltengagen A, Hennig T, Theil K, Rutkowski A, Ferrai C, Baer L, Kermas L, Friedel C, Rajewsky N, Akalin A, Dolken L, Grasser F, Landthaler M. Genome Biol. 2017 Oct 31;18(1):209. doi: 10.1186/s13059-017-1329-5. PubMed
Monitoring of Dual CRISPR/Cas9-Mediated Steroidogenic Acute Regulatory Protein Gene Deletion and Cholesterol Accumulation Using High-Resolution Fluorescence In Situ Hybridization in a Single Cell. Lee J, Jefcoate C. Front Endocrinol (Lausanne). 2017 Oct 25;8:289. doi: 10.3389/fendo.2017.00289. eCollection 2017. PubMed
A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples. Chen H, Li C, Peng X, Zhou Z, Weinstein JN, Liang H. Cell. 2018 Apr 5;173(2):386-399.e12. doi: 10.1016/j.cell.2018.03.027. PubMed
Fast-Evolving Human-Specific Neural Enhancers Are Associated with Aging-Related Diseases. Chen H, Li C, Zhou Z, Liang H. Cell Syst. 2018 May 23;6(5):604-611.e4. doi: 10.1016/j.cels.2018.04.002. PubMed
IMP/GTP balance modulates cytoophidium assembly and IMPDH activity. Keppeke GD, Chang CC, Peng M, Chen LY, Lin WC, Pai LM, Andrade LEC, Sung LY, Liu JL. Cell Div. 2018 Jun 15;13:5. doi: 10.1186/s13008-018-0038-0. eCollection 2018. PubMed
Viral diversity is an obligate consideration in CRISPR/Cas9 designs for targeting the HIV reservoir. Roychoudhury P, De Silva Feelixge H, Reeves D, Mayer BT, Stone D, Schiffer JT, Jerome KR. BMC Biol. 2018 Jul 11;16(1):75. doi: 10.1186/s12915-018-0544-1. PubMed
Long Non-Coding RNA Modulation of VEGF-A during Hypoxia. Nieminen T, Scott TA, Lin FM, Chen Z, Yla-Herttuala S, Morris KV. Noncoding RNA. 2018 Nov 20;4(4). pii: ncrna4040034. doi: 10.3390/ncrna4040034. PubMed
The planar cell polarity protein VANG-1/Vangl negatively regulates Wnt/beta-catenin signaling through a Dvl dependent mechanism. Mentink RA, Rella L, Radaszkiewicz TW, Gybel T, Betist MC, Bryja V, Korswagen HC. PLoS Genet. 2018 Dec 7;14(12):e1007840. doi: 10.1371/journal.pgen.1007840. eCollection 2018 Dec. PubMed
Streamlined procedure for gene knockouts using all-in-one adenoviral CRISPR-Cas9. Jin YH, Joo H, Lee K, Kim H, Didier R, Yang Y, Shin H, Lee C. Sci Rep. 2019 Jan 22;9(1):277. doi: 10.1038/s41598-018-36736-y. PubMed
Loss of Neurofascin-186 Disrupts Alignment of AnkyrinG Relative to Its Binding Partners in the Axon Initial Segment. Alpizar SA, Baker AL, Gulledge AT, Hoppa MB. Front Cell Neurosci. 2019 Jan 22;13:1. doi: 10.3389/fncel.2019.00001. eCollection 2019. PubMed
Transposable elements drive widespread expression of oncogenes in human cancers. Jang HS, Shah NM, Du AY, Dailey ZZ, Pehrsson EC, Godoy PM, Zhang D, Li D, Xing X, Kim S, O'Donnell D, Gordon JI, Wang T. Nat Genet. 2019 Apr;51(4):611-617. doi: 10.1038/s41588-019-0373-3. Epub 2019 Mar 29. PubMed
Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1. Harnos J, Canizal MCA, Jurasek M, Kumar J, Holler C, Schambony A, Hanakova K, Bernatik O, Zdrahal Z, Gomoryova K, Gybel T, Radaszkiewicz TW, Kravec M, Trantirek L, Rynes J, Dave Z, Fernandez-Llamazares AI, Vacha R, Tripsianes K, Hoffmann C, Bryja V. Nat Commun. 2019 Apr 18;10(1):1804. doi: 10.1038/s41467-019-09651-7. PubMed
Stimulation of CRISPR-mediated homology-directed repair by an engineered RAD18 variant. Nambiar TS, Billon P, Diedenhofen G, Hayward SB, Taglialatela A, Cai K, Huang JW, Leuzzi G, Cuella-Martin R, Palacios A, Gupta A, Egli D, Ciccia A. Nat Commun. 2019 Jul 30;10(1):3395. doi: 10.1038/s41467-019-11105-z. PubMed

Associated Plasmids

TRPM4 is highly expressed in human colorectal tumor buds and contributes to proliferation, cell cycle, and invasion of colorectal cancer cells. Kappel S, Stoklosa P, Hauert B, Ross-Kaschitza D, Borgstrom A, Baur R, Galvan JA, Zlobec I, Peinelt C. Mol Oncol. 2019 Nov;13(11):2393-2405. doi: 10.1002/1878-0261.12566. Epub 2019 Sep 12. PubMed
Recruitment of DNA Repair MRN Complex by Intrinsically Disordered Protein Domain Fused to Cas9 Improves Efficiency of CRISPR-Mediated Genome Editing. Reuven N, Adler J, Broennimann K, Myers N, Shaul Y. Biomolecules. 2019 Oct 8;9(10). pii: biom9100584. doi: 10.3390/biom9100584. PubMed

Associated Plasmids

Co-opted transposons help perpetuate conserved higher-order chromosomal structures. Choudhary MN, Friedman RZ, Wang JT, Jang HS, Zhuo X, Wang T. Genome Biol. 2020 Jan 24;21(1):16. doi: 10.1186/s13059-019-1916-8. PubMed
A genetic toolbox for metabolic engineering of Issatchenkia orientalis. Cao M, Fatma Z, Song X, Hsieh PH, Tran VG, Lyon WL, Sayadi M, Shao Z, Yoshikuni Y, Zhao H. Metab Eng. 2020 May;59:87-97. doi: 10.1016/j.ymben.2020.01.005. Epub 2020 Jan 31. PubMed
Optimized CRISPR/Cas9 strategy for homology-directed multiple targeted integration of transgenes in CHO cells. Shin SW, Lee JS. Biotechnol Bioeng. 2020 Jun;117(6):1895-1903. doi: 10.1002/bit.27315. Epub 2020 Mar 2. PubMed
CRISPR/Cas9-Induced Loss of Keap1 Enhances Anti-oxidation in Rat Adipose-Derived Mesenchymal Stem Cells. Hu Y, Liu S, Zhu BM. Front Neurol. 2020 Feb 18;10:1311. doi: 10.3389/fneur.2019.01311. eCollection 2019. PubMed
Enhancement of homology-directed repair with chromatin donor templates in cells. Cruz-Becerra G, Kadonaga JT. Elife. 2020 Apr 28;9. pii: 55780. doi: 10.7554/eLife.55780. PubMed
Comprehensive Analysis of Genomic Safe Harbors as Target Sites for Stable Expression of the Heterologous Gene in HEK293 Cells. Shin S, Kim SH, Shin SW, Grav LM, Pedersen LE, Lee JS, Lee GM. ACS Synth Biol. 2020 Jun 19;9(6):1263-1269. doi: 10.1021/acssynbio.0c00097. Epub 2020 Jun 2. PubMed
The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo. Bressan C, Pecora A, Gagnon D, Snapyan M, Labrecque S, De Koninck P, Parent M, Saghatelyan A. Elife. 2020 Sep 28;9. pii: 56006. doi: 10.7554/eLife.56006. PubMed
Cross-linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex. Spruijt CG, Grawe C, Kleinendorst SC, Baltissen MPA, Vermeulen M. FEBS J. 2021 May;288(10):3231-3245. doi: 10.1111/febs.15650. Epub 2020 Dec 14. PubMed
Adult neural stem cell activation in mice is regulated by the day/night cycle and intracellular calcium dynamics. Gengatharan A, Malvaut S, Marymonchyk A, Ghareghani M, Snapyan M, Fischer-Sternjak J, Ninkovic J, Gotz M, Saghatelyan A. Cell. 2021 Feb 4;184(3):709-722.e13. doi: 10.1016/j.cell.2020.12.026. Epub 2021 Jan 21. PubMed
Hydroxyurea selection for enhancement of homology-directed targeted integration of transgenes in CHO cells. Kwak JM, Lee Y, Shin SW, Lee JS. N Biotechnol. 2021 May 25;62:26-31. doi: 10.1016/j.nbt.2021.01.007. Epub 2021 Jan 21. PubMed
Dynamics of myogenic differentiation using a novel Myogenin knock-in reporter mouse. Benavente-Diaz M, Comai G, Di Girolamo D, Langa F, Tajbakhsh S. Skelet Muscle. 2021 Feb 18;11(1):5. doi: 10.1186/s13395-021-00260-x. PubMed
Omnitemporal choreographies of all five STIM/Orai and IP3Rs underlie the complexity of mammalian Ca(2+) signaling. Emrich SM, Yoast RE, Xin P, Arige V, Wagner LE, Hempel N, Gill DL, Sneyd J, Yule DI, Trebak M. Cell Rep. 2021 Mar 2;34(9):108760. doi: 10.1016/j.celrep.2021.108760. PubMed
Controlling Ratios of Plasmid-Based Double Cut Donor and CRISPR/Cas9 Components to Enhance Targeted Integration of Transgenes in Chinese Hamster Ovary Cells. Shin SW, Kim D, Lee JS. Int J Mol Sci. 2021 Feb 27;22(5). pii: ijms22052407. doi: 10.3390/ijms22052407. PubMed
Primary Cilia Formation Does Not Rely on WNT/beta-Catenin Signaling. Bernatik O, Paclikova P, Kotrbova A, Bryja V, Cajanek L. Front Cell Dev Biol. 2021 Feb 26;9:623753. doi: 10.3389/fcell.2021.623753. eCollection 2021. PubMed
Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion. Gangoso E, Southgate B, Bradley L, Rus S, Galvez-Cancino F, McGivern N, Guc E, Kapourani CA, Byron A, Ferguson KM, Alfazema N, Morrison G, Grant V, Blin C, Sou I, Marques-Torrejon MA, Conde L, Parrinello S, Herrero J, Beck S, Brandner S, Brennan PM, Bertone P, Pollard JW, Quezada SA, Sproul D, Frame MC, Serrels A, Pollard SM. Cell. 2021 Apr 29;184(9):2454-2470.e26. doi: 10.1016/j.cell.2021.03.023. Epub 2021 Apr 14. PubMed
Candidate Alzheimer's Disease Biomarker miR-483-5p Lowers TAU Phosphorylation by Direct ERK1/2 Repression. Nagaraj S, Want A, Laskowska-Kaszub K, Fesiuk A, Vaz S, Logarinho E, Wojda U. Int J Mol Sci. 2021 Apr 1;22(7). pii: ijms22073653. doi: 10.3390/ijms22073653. PubMed
Activation of Cilia-Independent Hedgehog/GLI1 Signaling as a Novel Concept for Neuroblastoma Therapy. Koeniger A, Brichkina A, Nee I, Dempwolff L, Hupfer A, Galperin I, Finkernagel F, Nist A, Stiewe T, Adhikary T, Diederich W, Lauth M. Cancers (Basel). 2021 Apr 15;13(8). pii: cancers13081908. doi: 10.3390/cancers13081908. PubMed
RNA transcripts stimulate homologous recombination by forming DR-loops. Ouyang J, Yadav T, Zhang JM, Yang H, Rheinbay E, Guo H, Haber DA, Lan L, Zou L. Nature. 2021 Jun;594(7862):283-288. doi: 10.1038/s41586-021-03538-8. Epub 2021 May 12. PubMed
MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus. Kaiser K, Jang A, Kompanikova P, Lun MP, Prochazka J, Machon O, Dani N, Prochazkova M, Laurent B, Gyllborg D, van Amerongen R, Fame RM, Gupta S, Wu F, Barker RA, Bukova I, Sedlacek R, Kozmik Z, Arenas E, Lehtinen MK, Bryja V. Development. 2021 May 15;148(10). pii: 268365. doi: 10.1242/dev.192054. Epub 2021 May 25. PubMed
Roles of individual human Dishevelled paralogs in the Wnt signalling pathways. Paclikova P, Radaszkiewicz TW, Potesil D, Harnos J, Zdrahal Z, Bryja V. Cell Signal. 2021 Sep;85:110058. doi: 10.1016/j.cellsig.2021.110058. Epub 2021 May 31. PubMed
HIRA stabilizes skeletal muscle lineage identity. Esteves de Lima J, Bou Akar R, Machado L, Li Y, Drayton-Libotte B, Dilworth FJ, Relaix F. Nat Commun. 2021 Jun 8;12(1):3450. doi: 10.1038/s41467-021-23775-9. PubMed
Live imaging of adult neural stem cells in freely behaving mice using mini-endoscopes. Malvaut S, Marymonchyk A, Gengatharan A, Saghatelyan A. STAR Protoc. 2021 Jun 12;2(2):100596. doi: 10.1016/j.xpro.2021.100596. eCollection 2021 Jun 18. PubMed
Small tandem DNA duplications result from CST-guided Pol alpha-primase action at DNA break termini. Schimmel J, Munoz-Subirana N, Kool H, van Schendel R, Tijsterman M. Nat Commun. 2021 Aug 10;12(1):4843. doi: 10.1038/s41467-021-25154-w. PubMed
Off-the-shelf proximity biotinylation for interaction proteomics. Santos-Barriopedro I, van Mierlo G, Vermeulen M. Nat Commun. 2021 Aug 18;12(1):5015. doi: 10.1038/s41467-021-25338-4. PubMed
Fast and Efficient Genome Editing of Human FOXP3(+) Regulatory T Cells. Van Zeebroeck L, Arroyo Hornero R, Corte-Real BF, Hamad I, Meissner TB, Kleinewietfeld M. Front Immunol. 2021 Aug 2;12:655122. doi: 10.3389/fimmu.2021.655122. eCollection 2021. PubMed
UTX condensation underlies its tumour-suppressive activity. Shi B, Li W, Song Y, Wang Z, Ju R, Ulman A, Hu J, Palomba F, Zhao Y, Le JP, Jarrard W, Dimoff D, Digman MA, Gratton E, Zang C, Jiang H. Nature. 2021 Sep;597(7878):726-731. doi: 10.1038/s41586-021-03903-7. Epub 2021 Sep 15. PubMed
CRISPR/Cas9 Ablation of Integrated HIV-1 Accumulates Proviral DNA Circles with Reformed Long Terminal Repeats. Lai M, Maori E, Quaranta P, Matteoli G, Maggi F, Sgarbanti M, Crucitta S, Pacini S, Turriziani O, Antonelli G, Heeney JL, Freer G, Pistello M. J Virol. 2021 Nov 9;95(23):e0135821. doi: 10.1128/JVI.01358-21. Epub 2021 Sep 22. PubMed
Matrix stiffness drives stromal autophagy and promotes formation of a protumorigenic niche. Hupfer A, Brichkina A, Koeniger A, Keber C, Denkert C, Pfefferle P, Helmprobst F, Pagenstecher A, Visekruna A, Lauth M. Proc Natl Acad Sci U S A. 2021 Oct 5;118(40). pii: 2105367118. doi: 10.1073/pnas.2105367118. PubMed
RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy. Radaszkiewicz T, Noskova M, Gomoryova K, Vondalova Blanarova O, Radaszkiewicz KA, Pickova M, Vichova R, Gybel T, Kaiser K, Demkova L, Kucerova L, Barta T, Potesil D, Zdrahal Z, Soucek K, Bryja V. Elife. 2021 Oct 27;10. pii: 65759. doi: 10.7554/eLife.65759. PubMed
A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes. Cheng YS, Zhang T, Ma X, Pratuangtham S, Zhang GC, Ondrus AA, Mafi A, Lomenick B, Jones JJ, Ondrus AE. Nat Chem Biol. 2021 Dec;17(12):1271-1280. doi: 10.1038/s41589-021-00907-2. Epub 2021 Nov 19. PubMed
Orai1 Boosts SK3 Channel Activation. Tiffner A, Hopl V, Schober R, Sallinger M, Grabmayr H, Hoglinger C, Fahrner M, Lunz V, Maltan L, Frischauf I, Krivic D, Bhardwaj R, Schindl R, Hediger MA, Derler I. Cancers (Basel). 2021 Dec 17;13(24). pii: cancers13246357. doi: 10.3390/cancers13246357. PubMed
Combined Inactivation of CTPS1 and ATR Is Synthetically Lethal to MYC-Overexpressing Cancer Cells. Sun Z, Zhang Z, Wang QQ, Liu JL. Cancer Res. 2022 Mar 15;82(6):1013-1024. doi: 10.1158/0008-5472.CAN-21-1707. PubMed
Identification of Helicoverpa armigera promoters for biotechnological applications. Samantsidis GR, Denecke S, Swevers L, Skavdis G, Geibel S, Vontas J. Insect Biochem Mol Biol. 2022 Mar;142:103725. doi: 10.1016/j.ibmb.2022.103725. Epub 2022 Jan 29. PubMed
Endogenous BiP reporter system for simultaneous identification of ER stress and antibody production in Chinese hamster ovary cells. Kyeong M, Lee JS. Metab Eng. 2022 Jul;72:35-45. doi: 10.1016/j.ymben.2022.02.002. Epub 2022 Feb 17. PubMed
CRISPR-Cas9-mediated induction of large chromosomal inversions in human bronchial epithelial cells. Angelopoulou A, Papaspyropoulos A, Papantonis A, Gorgoulis VG. STAR Protoc. 2022 Mar 18;3(2):101257. doi: 10.1016/j.xpro.2022.101257. eCollection 2022 Jun 17. PubMed
Cruciform DNA Structures Act as Legible Templates for Accelerating Homologous Recombination in Transgenic Animals. Ou-Yang H, Yang SH, Chen W, Yang SH, Cidem A, Sung LY, Chen CM. Int J Mol Sci. 2022 Apr 2;23(7). pii: ijms23073973. doi: 10.3390/ijms23073973. PubMed
Multidimensional chromatin profiling of zebrafish pancreas to uncover and investigate disease-relevant enhancers. Bordeira-Carrico R, Teixeira J, Duque M, Galhardo M, Ribeiro D, Acemel RD, Firbas PN, Tena JJ, Eufrasio A, Marques J, Ferreira FJ, Freitas T, Carneiro F, Gomez-Skarmeta JL, Bessa J. Nat Commun. 2022 Apr 11;13(1):1945. doi: 10.1038/s41467-022-29551-7. PubMed
p53 alters intracellular Ca(2+) signaling through regulation of TRPM4. Kappel S, Ross-Kaschitza D, Hauert B, Rother K, Peinelt C. Cell Calcium. 2022 Jun;104:102591. doi: 10.1016/j.ceca.2022.102591. Epub 2022 Apr 19. PubMed
CRISPR/Cas9 editing of the MYO7A gene in rhesus macaque embryos to generate a primate model of Usher syndrome type 1B. Ryu J, Statz JP, Chan W, Burch FC, Brigande JV, Kempton B, Porsov EV, Renner L, McGill T, Burwitz BJ, Hanna CB, Neuringer M, Hennebold JD. Sci Rep. 2022 Jun 16;12(1):10036. doi: 10.1038/s41598-022-13689-x. PubMed
H3K9 tri-methylation at Nanog times differentiation commitment and enables the acquisition of primitive endoderm fate. Dubois A, Vincenti L, Chervova A, Greenberg MVC, Vandormael-Pournin S, Bourc'his D, Cohen-Tannoudji M, Navarro P. Development. 2022 Sep 1;149(17):dev201074. doi: 10.1242/dev.201074. Epub 2022 Sep 7. PubMed
CRISPR-mediated activation of autism gene Itgb3 restores cortical network excitability via mGluR5 signaling. Jaudon F, Thalhammer A, Zentilin L, Cingolani LA. Mol Ther Nucleic Acids. 2022 Jul 20;29:462-480. doi: 10.1016/j.omtn.2022.07.013. eCollection 2022 Sep 13. PubMed
Identification and single-base gene-editing functional validation of a cis-EPO variant as a genetic predictor for EPO-increasing therapies. Harlow CE, Gandawijaya J, Bamford RA, Martin ER, Wood AR, van der Most PJ, Tanaka T, Leonard HL, Etheridge AS, Innocenti F, Beaumont RN, Tyrrell J, Nalls MA, Simonsick EM, Garimella PS, Shiroma EJ, Verweij N, van der Meer P, Gansevoort RT, Snieder H, Gallins PJ, Jima DD, Wright F, Zhou YH, Ferrucci L, Bandinelli S, Hernandez DG, van der Harst P, Patel VV, Waterworth DM, Chu AY, Oguro-Ando A, Frayling TM. Am J Hum Genet. 2022 Sep 1;109(9):1638-1652. doi: 10.1016/j.ajhg.2022.08.004. PubMed
SIQ: easy quantitative measurement of mutation profiles in sequencing data. van Schendel R, Schimmel J, Tijsterman M. NAR Genom Bioinform. 2022 Sep 5;4(3):lqac063. doi: 10.1093/nargab/lqac063. eCollection 2022 Sep. PubMed
Mitochondrial Protein Cox7b Is a Metabolic Sensor Driving Brain-Specific Metastasis of Human Breast Cancer Cells. Blackman MCNM, Capeloa T, Rondeau JD, Zampieri LX, Benyahia Z, Van de Velde JA, Fransolet M, Daskalopoulos EP, Michiels C, Beauloye C, Sonveaux P. Cancers (Basel). 2022 Sep 8;14(18):4371. doi: 10.3390/cancers14184371. PubMed
Inositol hexakisphosphate is required for Integrator function. Lin MH, Jensen MK, Elrod ND, Huang KL, Welle KA, Wagner EJ, Tong L. Nat Commun. 2022 Sep 30;13(1):5742. doi: 10.1038/s41467-022-33506-3. PubMed
Targeted integration in CHO cells using CRIS-PITCh/Bxb1 recombinase-mediated cassette exchange hybrid system. Ghanbari S, Bayat E, Azizi M, Fard-Esfahani P, Modarressi MH, Davami F. Appl Microbiol Biotechnol. 2023 Feb;107(2-3):769-783. doi: 10.1007/s00253-022-12322-1. Epub 2022 Dec 20. PubMed
Widespread contribution of transposable elements to the rewiring of mammalian 3D genomes. Choudhary MNK, Quaid K, Xing X, Schmidt H, Wang T. Nat Commun. 2023 Feb 6;14(1):634. doi: 10.1038/s41467-023-36364-9. PubMed
Targeting DNA repair pathways with B02 and Nocodazole small molecules to improve CRIS-PITCh mediated cassette integration in CHO-K1 cells. Rahmani B, Kheirandish MH, Ghanbari S, Raz A, Shamsi F, Davami F. Sci Rep. 2023 Feb 22;13(1):3116. doi: 10.1038/s41598-023-29863-8. PubMed
RNA Polymerase II transcription independent of TBP in murine embryonic stem cells. Kwan JZJ, Nguyen TF, Uzozie AC, Budzynski MA, Cui J, Lee JMC, Van Petegem F, Lange PF, Teves SS. Elife. 2023 Mar 30;12:e83810. doi: 10.7554/eLife.83810. PubMed

Associated Plasmids

Implementation of ubiquitous chromatin opening elements as artificial integration sites for CRISPR/Cas9-mediated knock-in in mammalian cells. Kim SM, Lee J, Lee JS. Eng Life Sci. 2023 Mar 9;23(4):e2200047. doi: 10.1002/elsc.202200047. eCollection 2023 Apr. PubMed
Upstream Stimulatory Factors Regulate HIV-1 Latency and Are Required for Robust T Cell Activation. Horvath RM, Sadowski I. Viruses. 2023 Jun 28;15(7):1470. doi: 10.3390/v15071470. PubMed
Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway. Pathak T, Benson JC, Johnson MT, Xin P, Abdelnaby AE, Walter V, Koltun WA, Yochum GS, Hempel N, Trebak M. bioRxiv [Preprint]. 2023 Oct 3:2023.10.02.560521. doi: 10.1101/2023.10.02.560521. PubMed
Regulation of astrocyte metabolism by mitochondrial translocator protein 18kDa. Firth W, Robb JL, Stewart D, Pye KR, Bamford R, Oguro-Ando A, Beall C, Ellacott KL. bioRxiv [Preprint]. 2023 Oct 2:2023.09.29.560159. doi: 10.1101/2023.09.29.560159. PubMed
Tmprss2 maintains epithelial barrier integrity and transepithelial sodium transport. Rickman OJ, Guignard E, Chabanon T, Bertoldi G, Auberson M, Hummler E. Life Sci Alliance. 2024 Jan 3;7(3):e202302304. doi: 10.26508/lsa.202302304. Print 2024 Mar. PubMed
Regulation of astrocyte metabolism by mitochondrial translocator protein 18 kDa. Firth W, Robb JL, Stewart D, Pye KR, Bamford R, Oguro-Ando A, Beall C, Ellacott KLJ. J Neurochem. 2024 Jul;168(7):1374-1401. doi: 10.1111/jnc.16089. Epub 2024 Mar 14. PubMed
Context-dependent genomic locus effects on antibody production in recombinant Chinese hamster ovary cells generated through random integration. Woo HJ, Kim J, Kim SM, Kim D, Moon JY, Park D, Lee JS. Comput Struct Biotechnol J. 2024 Apr 10;23:1654-1665. doi: 10.1016/j.csbj.2024.04.023. eCollection 2024 Dec. PubMed
Deciphering lineage specification during early embryogenesis in mouse gastruloids using multilayered proteomics. Stelloo S, Alejo-Vinogradova MT, van Gelder CAGH, Zijlmans DW, van Oostrom MJ, Valverde JM, Lamers LA, Rus T, Sobrevals Alcaraz P, Schafers T, Furlan C, Jansen PWTC, Baltissen MPA, Sonnen KF, Burgering B, Altelaar MAFM, Vos HR, Vermeulen M. Cell Stem Cell. 2024 Jul 5;31(7):1072-1090.e8. doi: 10.1016/j.stem.2024.04.017. Epub 2024 May 15. PubMed
An oncogenic enhancer promotes melanoma progression via regulating ETV4 expression. Zhang J, Wang Q, Qi S, Duan Y, Liu Z, Liu J, Zhang Z, Li C. J Transl Med. 2024 Jun 7;22(1):547. doi: 10.1186/s12967-024-05356-8. PubMed

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