Addgene: dCAS9-VP64_GFP Citations

dCAS9-VP64_GFP Citations (54)

Originally described in: Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.
Konermann S, Brigham MD, Trevino AE, Joung J, Abudayyeh OO, Barcena C, Hsu PD, Habib N, Gootenberg JS, Nishimasu H, Nureki O, Zhang F Nature. 2014 Dec 10. doi: 10.1038/nature14136. PubMed Journal

Articles Citing dCAS9-VP64_GFP

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The sirtuin-associated human senescence program converges on the activation of placenta-specific gene PAPPA. Bi S, Jiang X, Ji Q, Wang Z, Ren J, Wang S, Yu Y, Wang R, Liu Z, Liu J, Hu J, Sun G, Wu Z, Diao Z, Li J, Sun L, Izpisua Belmonte JC, Zhang W, Liu GH, Qu J. Dev Cell. 2024 Apr 22;59(8):991-1009.e12. doi: 10.1016/j.devcel.2024.02.008. Epub 2024 Mar 13. PubMed
A novel lentiviral vector-based approach to generate chimeric antigen receptor T cells targeting Aspergillus fumigatus. Kumaresan PR, Wurster S, Bavisi K, da Silva TA, Hauser P, Kinnitt J, Albert ND, Bharadwaj U, Neelapu S, Kontoyiannis DP. mBio. 2024 Apr 10;15(4):e0341323. doi: 10.1128/mbio.03413-23. Epub 2024 Feb 28. PubMed
A lncRNA identifies Irf8 enhancer element in negative feedback control of dendritic cell differentiation. Xu H, Li Z, Kuo CC, Gotz K, Look T, de Toledo MAS, Sere K, Costa IG, Zenke M. Elife. 2023 Mar 14;12:e83342. doi: 10.7554/eLife.83342. PubMed
Activation of stably silenced genes by recruitment of a synthetic de-methylating module. Chan WF, Coughlan HD, Chen Y, Keenan CR, Smyth GK, Perkins AC, Johanson TM, Allan RS. Nat Commun. 2022 Sep 23;13(1):5582. doi: 10.1038/s41467-022-33181-4. PubMed Associated Plasmids dCas9-5xGCN4-P2A-BFP scFv-GCN4-sfGFP-TET1CD MS2-p65-HSF1-P2A-mCherry gRNA-MS2x2-TagRFP657 scFv-GCN4-sfGFP-deadTET1CD
CRISPR-mediated activation of autism gene Itgb3 restores cortical network excitability via mGluR5 signaling. Jaudon F, Thalhammer A, Zentilin L, Cingolani LA. Mol Ther Nucleic Acids. 2022 Jul 20;29:462-480. doi: 10.1016/j.omtn.2022.07.013. eCollection 2022 Sep 13. PubMed
Arc Regulates Transcription of Genes for Plasticity, Excitability and Alzheimer's Disease. Leung HW, Foo G, VanDongen A. Biomedicines. 2022 Aug 11;10(8):1946. doi: 10.3390/biomedicines10081946. PubMed
A Ctnnb1 enhancer regulates neocortical neurogenesis by controlling the abundance of intermediate progenitors. Wang J, Wang A, Tian K, Hua X, Zhang B, Zheng Y, Kong X, Li W, Xu L, Wang J, Li Z, Liu Y, Zhou Y. Cell Discov. 2022 Aug 2;8(1):74. doi: 10.1038/s41421-022-00421-2. PubMed
YAP1 induces invadopodia formation by transcriptionally activating TIAM1 through enhancer in breast cancer. Shen J, Huang Q, Jia W, Feng S, Liu L, Li X, Tao D, Xie D. Oncogene. 2022 Jul;41(31):3830-3845. doi: 10.1038/s41388-022-02344-4. Epub 2022 Jun 30. PubMed
PAM-flexible dual base editor-mediated random mutagenesis and self-activation strategies to improve CRISPRa potency. Lau CH, Huang S, Lam RHW, Tin C. Mol Ther Methods Clin Dev. 2022 May 29;26:26-37. doi: 10.1016/j.omtm.2022.05.005. eCollection 2022 Sep 8. PubMed
CRISPR activation screen identifies TGFbeta-associated PEG10 as a crucial tumor suppressor in Ewing sarcoma. Saratov V, Ngo QA, Pedot G, Sidorov S, Wachtel M, Niggli FK, Schafer BW. Sci Rep. 2022 Jun 23;12(1):10671. doi: 10.1038/s41598-022-12659-7. PubMed

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