pCDH-puro-cMyc Citations (39)
Originally described in: Inhibition of BET bromodomain targets genetically diverse glioblastoma.Cheng Z, Gong Y, Ma Y, Lu K, Lu X, Pierce LA, Thompson RC, Muller S, Knapp S, Wang J Clin Cancer Res. 2013 Apr 1;19(7):1748-59. doi: 10.1158/1078-0432.CCR-12-3066. Epub 2013 Feb 12. PubMed Journal
Articles Citing pCDH-puro-cMyc
| Articles |
|---|
| Myc-driven glycolysis is a therapeutic target in glioblastoma. Tateishi K, Iafrate AJ, Ho Q, Curry WT, Batchelor T, Flaherty KT, Onozato M, Lelic N, Sundaram S, Cahill DP, Chi AS, Wakimoto H. Clin Cancer Res. 2016 Apr 13. pii: clincanres.2274.2015. PubMed |
| Loss of TRIM33 causes resistance to BET bromodomain inhibitors through MYC- and TGF-beta-dependent mechanisms. Shi X, Mihaylova VT, Kuruvilla L, Chen F, Viviano S, Baldassarre M, Sperandio D, Martinez R, Yue P, Bates JG, Breckenridge DG, Schlessinger J, Turk BE, Calderwood DA. Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):E4558-66. doi: 10.1073/pnas.1608319113. Epub 2016 Jul 18. PubMed |
| Ad E1A 243R oncoprotein promotes association of proto-oncogene product MYC with the NuA4/Tip60 complex via the E1A N-terminal repression domain. Zhao LJ, Loewenstein PM, Green M. Virology. 2016 Dec;499:178-184. doi: 10.1016/j.virol.2016.09.005. Epub 2016 Sep 22. PubMed |
| The epichaperome is an integrated chaperome network that facilitates tumour survival. Rodina A, Wang T, Yan P, Gomes ED, Dunphy MP, Pillarsetty N, Koren J, Gerecitano JF, Taldone T, Zong H, Caldas-Lopes E, Alpaugh M, Corben A, Riolo M, Beattie B, Pressl C, Peter RI, Xu C, Trondl R, Patel HJ, Shimizu F, Bolaender A, Yang C, Panchal P, Farooq MF, Kishinevsky S, Modi S, Lin O, Chu F, Patil S, Erdjument-Bromage H, Zanzonico P, Hudis C, Studer L, Roboz GJ, Cesarman E, Cerchietti L, Levine R, Melnick A, Larson SM, Lewis JS, Guzman ML, Chiosis G. Nature. 2016 Oct 20;538(7625):397-401. doi: 10.1038/nature19807. Epub 2016 Oct 5. PubMed |
| The caspase-3/p120 RasGAP stress-sensing module reduces liver cancer incidence but does not affect overall survival in gamma-irradiated and carcinogen-treated mice. Vanli G, Sempoux C, Widmann C. Mol Carcinog. 2017 Jun;56(6):1680-1684. doi: 10.1002/mc.22624. Epub 2017 Feb 16. PubMed |
| RNA Polymerase I Inhibition with CX-5461 as a Novel Therapeutic Strategy to Target MYC in Multiple Myeloma. Lee HC, Wang H, Baladandayuthapani V, Lin H, He J, Jones RJ, Kuiatse I, Gu D, Wang Z, Ma W, Lim J, O'Brien S, Keats J, Yang J, Davis RE, Orlowski RZ. Br J Haematol. 2017 Apr;177(1):80-94. doi: 10.1111/bjh.14525. PubMed |
| Chaperone-mediated autophagy prevents cellular transformation by regulating MYC proteasomal degradation. Gomes LR, Menck CFM, Cuervo AM. Autophagy. 2017 May 4;13(5):928-940. doi: 10.1080/15548627.2017.1293767. Epub 2017 Mar 2. PubMed |
| The cell polarity protein Scrib functions as a tumor suppressor in liver cancer. Kapil S, Sharma BK, Patil M, Elattar S, Yuan J, Hou SX, Kolhe R, Satyanarayana A. Oncotarget. 2017 Apr 18;8(16):26515-26531. doi: 10.18632/oncotarget.15713. PubMed |
| Adenovirus E1A TRRAP-targeting domain-mediated enhancement of MYC association with the NuA4 complex activates a panel of MYC target genes enriched for gene expression and ribosome biogenesis. Zhao LJ, Loewenstein PM, Green M. Virology. 2017 Dec;512:172-179. doi: 10.1016/j.virol.2017.08.010. Epub 2017 Sep 28. PubMed |
| Induced Pluripotent Stem Cells from Ovarian Tissue. Salas S, Ng N, Gerami-Naini B, Anchan RM. Curr Protoc Hum Genet. 2017 Oct 18;95:21.10.1-21.10.22. doi: 10.1002/cphg.47. PubMed |
| Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer. Topper MJ, Vaz M, Chiappinelli KB, DeStefano Shields CE, Niknafs N, Yen RC, Wenzel A, Hicks J, Ballew M, Stone M, Tran PT, Zahnow CA, Hellmann MD, Anagnostou V, Strissel PL, Strick R, Velculescu VE, Baylin SB. Cell. 2017 Nov 30;171(6):1284-1300.e21. doi: 10.1016/j.cell.2017.10.022. PubMed |
R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m(6)A/MYC/CEBPA Signaling.
Su R, Dong L, Li C, Nachtergaele S, Wunderlich M, Qing Y, Deng X, Wang Y, Weng X, Hu C, Yu M, Skibbe J, Dai Q, Zou D, Wu T, Yu K, Weng H, Huang H, Ferchen K, Qin X, Zhang B, Qi J, Sasaki AT, Plas DR, Bradner JE, Wei M, Marcucci G, Jiang X, Mulloy JC, Jin J, He C, Chen J.
Cell. 2018 Jan 11;172(1-2):90-105.e23. doi: 10.1016/j.cell.2017.11.031. Epub 2017 Dec 14.
PubMed
Associated Plasmids |
| Glutamine-utilizing transaminases are a metabolic vulnerability of TAZ/YAP-activated cancer cells. Yang CS, Stampouloglou E, Kingston NM, Zhang L, Monti S, Varelas X. EMBO Rep. 2018 Jun;19(6). pii: embr.201643577. doi: 10.15252/embr.201643577. Epub 2018 Apr 16. PubMed |
| c-MYC Drives Breast Cancer Metastasis to the Brain, but Promotes Synthetic Lethality with TRAIL. Lee HY, Cha J, Kim SK, Park JH, Song KH, Kim P, Kim MY. Mol Cancer Res. 2019 Feb;17(2):544-554. doi: 10.1158/1541-7786.MCR-18-0630. Epub 2018 Sep 28. PubMed |
| MiR-584-5p potentiates vincristine and radiation response by inducing spindle defects and DNA damage in medulloblastoma. Abdelfattah N, Rajamanickam S, Panneerdoss S, Timilsina S, Yadav P, Onyeagucha BC, Garcia M, Vadlamudi R, Chen Y, Brenner A, Houghton P, Rao MK. Nat Commun. 2018 Oct 31;9(1):4541. doi: 10.1038/s41467-018-06808-8. PubMed |
| Estrogen-independent Myc overexpression confers endocrine therapy resistance on breast cancer cells expressing ERalphaY537S and ERalphaD538G mutations. Yu L, Wang L, Mao C, Duraki D, Kim JE, Huang R, Helferich WG, Nelson ER, Park BH, Shapiro DJ. Cancer Lett. 2019 Feb 1;442:373-382. doi: 10.1016/j.canlet.2018.10.041. Epub 2018 Nov 9. PubMed |
| Targeting ubiquitin-activating enzyme induces ER stress-mediated apoptosis in B-cell lymphoma cells. Best S, Hashiguchi T, Kittai A, Bruss N, Paiva C, Okada C, Liu T, Berger A, Danilov AV. Blood Adv. 2019 Jan 8;3(1):51-62. doi: 10.1182/bloodadvances.2018026880. PubMed |
| Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation. Varum S, Baggiolini A, Zurkirchen L, Atak ZK, Cantu C, Marzorati E, Bossart R, Wouters J, Hausel J, Tuncer E, Zingg D, Veen D, John N, Balz M, Levesque MP, Basler K, Aerts S, Zamboni N, Dummer R, Sommer L. Cell Stem Cell. 2019 Apr 4;24(4):637-653.e9. doi: 10.1016/j.stem.2019.03.011. PubMed |
| Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway. Lee YR, Chen M, Lee JD, Zhang J, Lin SY, Fu TM, Chen H, Ishikawa T, Chiang SY, Katon J, Zhang Y, Shulga YV, Bester AC, Fung J, Monteleone E, Wan L, Shen C, Hsu CH, Papa A, Clohessy JG, Teruya-Feldstein J, Jain S, Wu H, Matesic L, Chen RH, Wei W, Pandolfi PP. Science. 2019 May 17;364(6441). pii: 364/6441/eaau0159. doi: 10.1126/science.aau0159. PubMed |
| Cyclin-dependent kinase-9 is a therapeutic target in MYC-expressing diffuse large B-cell lymphoma. Hashiguchi T, Bruss N, Best S, Lam V, Danilova O, Paiva CJ, Wolf J, Gilbert EW, Okada CY, Kaur P, Drew L, Cidado J, Hurlin P, Danilov AV. Mol Cancer Ther. 2019 Jun 26. pii: 1535-7163.MCT-18-1023. doi: 10.1158/1535-7163.MCT-18-1023. PubMed |
| A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells. Guo L, Li J, Zeng H, Guzman AG, Li T, Lee M, Zhou Y, Goodell MA, Stephan C, Davies PJA, Dawson MA, Sun D, Huang Y. Nat Commun. 2020 Feb 6;11(1):740. doi: 10.1038/s41467-020-14604-6. PubMed |
| Reversible expansion of pancreatic islet progenitors derived from human induced pluripotent stem cells. Tanaka A, Watanabe A, Nakano Y, Matsumoto M, Okazaki Y, Miyajima A. Genes Cells. 2020 May;25(5):302-311. doi: 10.1111/gtc.12759. Epub 2020 Mar 6. PubMed |
| Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer. Lin KH, Rutter JC, Xie A, Pardieu B, Winn ET, Bello RD, Forget A, Itzykson R, Ahn YR, Dai Z, Sobhan RT, Anderson GR, Singleton KR, Decker AE, Winter PS, Locasale JW, Crawford L, Puissant A, Wood KC. Nat Genet. 2020 Apr;52(4):408-417. doi: 10.1038/s41588-020-0590-9. Epub 2020 Mar 16. PubMed |
| Molecular basis for ubiquitin ligase CRL2(FEM1C)-mediated recognition of C-degron. Yan X, Wang X, Li Y, Zhou M, Li Y, Song L, Mi W, Min J, Dong C. Nat Chem Biol. 2021 Mar;17(3):263-271. doi: 10.1038/s41589-020-00703-4. Epub 2021 Jan 4. PubMed |
| Crizotinib Resistance Mediated by Autophagy Is Higher in the Stem-Like Cell Subset in ALK-Positive Anaplastic Large Cell Lymphoma, and This Effect Is MYC-Dependent. Shang C, Hassan B, Haque M, Song Y, Li J, Liu D, Lipke E, Chen W, Giuriato S, Lai R. Cancers (Basel). 2021 Jan 7;13(2). pii: cancers13020181. doi: 10.3390/cancers13020181. PubMed |
| An animal model for mitochondrial tyrosyl-tRNA synthetase deficiency reveals links between oxidative phosphorylation and retinal function. Jin X, Zhang Z, Nie Z, Wang C, Meng F, Yi Q, Chen M, Sun J, Zou J, Jiang P, Guan MX. J Biol Chem. 2021 Jan-Jun;296:100437. doi: 10.1016/j.jbc.2021.100437. Epub 2021 Feb 19. PubMed |
| Squalene epoxidase promotes colorectal cancer cell proliferation through accumulating calcitriol and activating CYP24A1-mediated MAPK signaling. He L, Li H, Pan C, Hua Y, Peng J, Zhou Z, Zhao Y, Lin M. Cancer Commun (Lond). 2021 Aug;41(8):726-746. doi: 10.1002/cac2.12187. Epub 2021 Jul 16. PubMed |
| Bovine mammary alveolar MAC-T cells afford a tool for studies of bovine milk exosomes in drug delivery. Ogunnaike M, Wang H, Zempleni J. Int J Pharm. 2021 Dec 15;610:121263. doi: 10.1016/j.ijpharm.2021.121263. Epub 2021 Nov 4. PubMed |
Androgen receptor and MYC equilibration centralizes on developmental super-enhancer.
Guo H, Wu Y, Nouri M, Spisak S, Russo JW, Sowalsky AG, Pomerantz MM, Wei Z, Korthauer K, Seo JH, Wang L, Arai S, Freedman ML, He HH, Chen S, Balk SP.
Nat Commun. 2021 Dec 15;12(1):7308. doi: 10.1038/s41467-021-27077-y.
PubMed
Associated Plasmids |
| Squalene synthase predicts poor prognosis in stage I-III colon adenocarcinoma and synergizes squalene epoxidase to promote tumor progression. Jiang H, Tang E, Chen Y, Liu H, Zhao Y, Lin M, He L. Cancer Sci. 2022 Mar;113(3):971-985. doi: 10.1111/cas.15248. Epub 2022 Jan 6. PubMed |
| DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy. Imberechts D, Kinnart I, Wauters F, Terbeek J, Manders L, Wierda K, Eggermont K, Madeiro RF, Sue C, Verfaillie C, Vandenberghe W. Brain. 2022 Dec 19;145(12):4368-4384. doi: 10.1093/brain/awac313. PubMed |
| Androgen receptor activity in prostate cancer dictates efficacy of bipolar androgen therapy through MYC. Sena LA, Kumar R, Sanin DE, Thompson EA, Rosen DM, Dalrymple SL, Antony L, Yang Y, Gomes-Alexandre C, Hicks JL, Jones T, Bowers KA, Eskra JN, Meyers J, Gupta A, Skaist A, Yegnasubramanian S, Luo J, Brennen WN, Kachhap SK, Antonarakis ES, De Marzo AM, Isaacs JT, Markowski MC, Denmeade SR. J Clin Invest. 2022 Dec 1;132(23):e162396. doi: 10.1172/JCI162396. PubMed |
| Loss of G0/G1 switch gene 2 (G0S2) promotes disease progression and drug resistance in chronic myeloid leukaemia (CML) by disrupting glycerophospholipid metabolism. Gonzalez MA, Olivas IM, Bencomo-Alvarez AE, Rubio AJ, Barreto-Vargas C, Lopez JL, Dang SK, Solecki JP, McCall E, Astudillo G, Velazquez VV, Schenkel K, Reffell K, Perkins M, Nguyen N, Apaflo JN, Alvidrez E, Young JE, Lara JJ, Yan D, Senina A, Ahmann J, Varley KE, Mason CC, Eide CA, Druker BJ, Nurunnabi M, Padilla O, Bajpeyi S, Eiring AM. Clin Transl Med. 2022 Dec;12(12):e1146. doi: 10.1002/ctm2.1146. PubMed |
| Engineering of Chinese hamster ovary cells for co-overexpressing MYC and XBP1s increased cell proliferation and recombinant EPO production. Latorre Y, Torres M, Vergara M, Berrios J, Sampayo MM, Godecke N, Wirth D, Hauser H, Dickson AJ, Altamirano C. Sci Rep. 2023 Jan 27;13(1):1482. doi: 10.1038/s41598-023-28622-z. PubMed |
| Discovery of antibodies targeting multipass transmembrane proteins using a suspension cell-based evolutionary approach. Krohl PJ, Fine J, Yang H, VanDyke D, Ang Z, Kim KB, Thomas-Tikhonenko A, Spangler JB. Cell Rep Methods. 2023 Mar 15;3(3):100429. doi: 10.1016/j.crmeth.2023.100429. eCollection 2023 Mar 27. PubMed |
| Splicing Factor SRSF1 Promotes Pancreatitis and KRASG12D-Mediated Pancreatic Cancer. Wan L, Lin KT, Rahman MA, Ishigami Y, Wang Z, Jensen MA, Wilkinson JE, Park Y, Tuveson DA, Krainer AR. Cancer Discov. 2023 Jul 7;13(7):1678-1695. doi: 10.1158/2159-8290.CD-22-1013. PubMed |
| USP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticity. Kwon J, Zhang J, Mok B, Allsup S, Kim C, Toretsky J, Han C. Mol Cancer. 2023 Dec 13;22(1):204. doi: 10.1186/s12943-023-01892-x. PubMed |
| Targeting ST8SIA6-AS1 counteracts KRAS(G12C) inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling. Wang Y, Yao M, Li C, Yang K, Qin X, Xu L, Shi S, Yu C, Meng X, Xie C. Exp Hematol Oncol. 2023 Dec 16;12(1):105. doi: 10.1186/s40164-023-00466-3. PubMed |
| BET inhibition induces synthetic lethality in PTEN deficient colorectal cancers via dual action on p21(CIP1/WAF1). Ren G, Chen J, Pu Y, Yang EJ, Tao S, Mou PK, Chen LJ, Zhu W, Chan KL, Luo G, Deng C, Shim JS. Int J Biol Sci. 2024 Mar 11;20(6):1978-1991. doi: 10.7150/ijbs.91867. eCollection 2024. PubMed |
If you have published an article using this material, please email us at [email protected] to have your article added to this page.