pcDNA3-AKT-PH-GFP Citations (27)
Originally described in: Integration of phosphoinositide- and calmodulin-mediated regulation of TRPC6.Kwon Y, Hofmann T, Montell C Mol Cell. 2007 Feb 23. 25(4):491-503. PubMed Journal
Articles Citing pcDNA3-AKT-PH-GFP
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| In vivo, site-specific, covalent conjugation of quantum dots to proteins via split-intein splicing. Charalambous A, Andreou M, Antoniades I, Christodoulou N, Skourides PA. Methods Mol Biol. 2012;906:157-69. doi: 10.1007/978-1-61779-953-2_11. PubMed |
| Functional analysis of non-hotspot AKT1 mutants found in human breast cancers identifies novel driver mutations: implications for personalized medicine. Yi KH, Axtmayer J, Gustin JP, Rajpurohit A, Lauring J. Oncotarget. 2013 Jan;4(1):29-34. PubMed |
| PKD1 mediates negative feedback of PI3K/Akt activation in response to G protein-coupled receptors. Ni Y, Sinnett-Smith J, Young SH, Rozengurt E. PLoS One. 2013 Sep 9;8(9):e73149. doi: 10.1371/journal.pone.0073149. eCollection 2013. PubMed |
Subcellular optogenetic inhibition of G proteins generates signaling gradients and cell migration.
O'Neill PR, Gautam N.
Mol Biol Cell. 2014 Aug 1;25(15):2305-14. doi: 10.1091/mbc.E14-04-0870. Epub 2014 Jun 11.
PubMed
Associated Plasmids |
| Osmotic surveillance mediates rapid wound closure through nucleotide release. Gault WJ, Enyedi B, Niethammer P. J Cell Biol. 2014 Dec 22;207(6):767-82. doi: 10.1083/jcb.201408049. PubMed |
| Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2. Soares HP, Ming M, Mellon M, Young SH, Han L, Sinnet-Smith J, Rozengurt E. Mol Cancer Ther. 2015 Apr;14(4):1014-23. doi: 10.1158/1535-7163.MCT-14-0669. Epub 2015 Feb 11. PubMed |
| Differential requirement of F-actin and microtubule cytoskeleton in cue-induced local protein synthesis in axonal growth cones. Piper M, Lee AC, van Horck FP, McNeilly H, Lu TB, Harris WA, Holt CE. Neural Dev. 2015 Feb 25;10:3. doi: 10.1186/s13064-015-0031-0. PubMed |
| Ubl4A is required for insulin-induced Akt plasma membrane translocation through promotion of Arp2/3-dependent actin branching. Zhao Y, Lin Y, Zhang H, Manas A, Tang W, Zhang Y, Wu D, Lin A, Xiang J. Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):9644-9. doi: 10.1073/pnas.1508647112. Epub 2015 Jul 20. PubMed |
| KCNJ15/Kir4.2 couples with polyamines to sense weak extracellular electric fields in galvanotaxis. Nakajima K, Zhu K, Sun YH, Hegyi B, Zeng Q, Murphy CJ, Small JV, Chen-Izu Y, Izumiya Y, Penninger JM, Zhao M. Nat Commun. 2015 Oct 9;6:8532. doi: 10.1038/ncomms9532. PubMed |
| Abrus agglutinin, a type II ribosome inactivating protein inhibits Akt/PH domain to induce endoplasmic reticulum stress mediated autophagy-dependent cell death. Panda PK, Behera B, Meher BR, Das DN, Mukhopadhyay S, Sinha N, Naik PP, Roy B, Das J, Paul S, Maiti TK, Agarwal R, Bhutia SK. Mol Carcinog. 2016 May 16. doi: 10.1002/mc.22502. PubMed |
| Distinct Roles for the N- and C-terminal Regions of M-Sec in Plasma Membrane Deformation during Tunneling Nanotube Formation. Kimura S, Yamashita M, Yamakami-Kimura M, Sato Y, Yamagata A, Kobashigawa Y, Inagaki F, Amada T, Hase K, Iwanaga T, Ohno H, Fukai S. Sci Rep. 2016 Sep 15;6:33548. doi: 10.1038/srep33548. PubMed |
| RalF-Mediated Activation of Arf6 Controls Rickettsia typhi Invasion by Co-Opting Phosphoinositol Metabolism. Rennoll-Bankert KE, Rahman MS, Guillotte ML, Lehman SS, Beier-Sexton M, Gillespie JJ, Azad AF. Infect Immun. 2016 Nov 18;84(12):3496-3506. Print 2016 Dec. PubMed |
| Insulin Receptor and GPCR Crosstalk Stimulates YAP via PI3K and PKD in Pancreatic Cancer Cells. Hao F, Xu Q, Zhao Y, Stevens JV, Young SH, Sinnett-Smith J, Rozengurt E. Mol Cancer Res. 2017 Jul;15(7):929-941. doi: 10.1158/1541-7786.MCR-17-0023. Epub 2017 Mar 30. PubMed |
| Manipulation of the Host Cell Membrane during Plasmodium Liver Stage Egress. Burda PC, Caldelari R, Heussler VT. MBio. 2017 Apr 11;8(2). pii: e00139-17. doi: 10.1128/mBio.00139-17. PubMed |
Myosin 1b promotes axon formation by regulating actin wave propagation and growth cone dynamics.
Iuliano O, Yoshimura A, Prosperi MT, Martin R, Knolker HJ, Coudrier E.
J Cell Biol. 2018 Jun 4;217(6):2033-2046. doi: 10.1083/jcb.201703205. Epub 2018 Mar 27.
PubMed
Associated Plasmids |
| TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy. Nnah IC, Wang B, Saqcena C, Weber GF, Bonder EM, Bagley D, De Cegli R, Napolitano G, Medina DL, Ballabio A, Dobrowolski R. Autophagy. 2019 Jan;15(1):151-164. doi: 10.1080/15548627.2018.1511504. Epub 2018 Sep 10. PubMed |
| The flavonoid baicalin improves glucose metabolism by targeting the PH domain of AKT and activating AKT/GSK3beta phosphorylation. Yang S, Zhang Y, Shen F, Ma X, Zhang M, Hou Y, Bai G. FEBS Lett. 2019 Jan;593(2):175-186. doi: 10.1002/1873-3468.13305. Epub 2018 Dec 17. PubMed |
| Leukocyte Cytoskeleton Polarization Is Initiated by Plasma Membrane Curvature from Cell Attachment. Ren C, Yuan Q, Braun M, Zhang X, Petri B, Zhang J, Kim D, Guez-Haddad J, Xue W, Pan W, Fan R, Kubes P, Sun Z, Opatowsky Y, Polleux F, Karatekin E, Tang W, Wu D. Dev Cell. 2019 Apr 22;49(2):206-219.e7. doi: 10.1016/j.devcel.2019.02.023. Epub 2019 Mar 28. PubMed |
| Metformin inhibits beta-catenin phosphorylation on Ser-552 through an AMPK/PI3K/Akt pathway in colorectal cancer cells. Amable G, Martinez-Leon E, Picco ME, Di Siervi N, Davio C, Rozengurt E, Rey O. Int J Biochem Cell Biol. 2019 Jul;112:88-94. doi: 10.1016/j.biocel.2019.05.004. Epub 2019 May 10. PubMed |
| Lipophilic statins inhibit YAP nuclear localization, co-activator activity and colony formation in pancreatic cancer cells and prevent the initial stages of pancreatic ductal adenocarcinoma in KrasG12D mice. Hao F, Xu Q, Wang J, Yu S, Chang HH, Sinnett-Smith J, Eibl G, Rozengurt E. PLoS One. 2019 May 17;14(5):e0216603. doi: 10.1371/journal.pone.0216603. eCollection 2019. PubMed |
| Expression of integrins to control migration direction of electrotaxis. Zhu K, Takada Y, Nakajima K, Sun Y, Jiang J, Zhang Y, Zeng Q, Takada Y, Zhao M. FASEB J. 2019 Aug;33(8):9131-9141. doi: 10.1096/fj.201802657R. Epub 2019 May 22. PubMed |
| Mcl-1 Interacts with Akt to Promote Lung Cancer Progression. Chen G, Park D, Magis AT, Behera M, Ramalingam SS, Owonikoko TK, Sica GL, Ye K, Zhang C, Chen Z, Curran WJ, Deng X. Cancer Res. 2019 Dec 15;79(24):6126-6138. doi: 10.1158/0008-5472.CAN-19-0950. Epub 2019 Oct 29. PubMed |
| Risk1, a Phosphatidylinositol 3-Kinase Effector, Promotes Rickettsia typhi Intracellular Survival. Voss OH, Gillespie JJ, Lehman SS, Rennoll SA, Beier-Sexton M, Rahman MS, Azad AF. mBio. 2020 Jun 16;11(3). pii: mBio.00820-20. doi: 10.1128/mBio.00820-20. PubMed |
| The Gb3-enriched CD59/flotillin plasma membrane domain regulates host cell invasion by Pseudomonas aeruginosa. Brandel A, Aigal S, Lagies S, Schlimpert M, Melendez AV, Xu M, Lehmann A, Hummel D, Fisch D, Madl J, Eierhoff T, Kammerer B, Romer W. Cell Mol Life Sci. 2021 Apr;78(7):3637-3656. doi: 10.1007/s00018-021-03766-1. Epub 2021 Feb 8. PubMed |
| Methylene-bridge tryptophan fatty acylation regulates PI3K-AKT signaling and glucose uptake. Hu SH, He XD, Nie J, Hou JL, Wu J, Liu XY, Wei Y, Tang HR, Sun WX, Zhou SX, Yuan YY, An YP, Yan GQ, Lin Y, Lin PC, Zhao JJ, Ye ML, Zhao JY, Xu W, Zhao SM. Cell Rep. 2022 Mar 15;38(11):110509. doi: 10.1016/j.celrep.2022.110509. PubMed |
| Human cytomegalovirus attenuates AKT activity by destabilizing insulin receptor substrate proteins. Domma AJ, Goodrum FD, Moorman NJ, Kamil JP. bioRxiv. 2023 Apr 17:2023.04.17.537203. doi: 10.1101/2023.04.17.537203. Preprint. PubMed |
| Human cytomegalovirus attenuates AKT activity by destabilizing insulin receptor substrate proteins. Domma AJ, Henderson LA, Goodrum FD, Moorman NJ, Kamil JP. J Virol. 2023 Oct 31;97(10):e0056323. doi: 10.1128/jvi.00563-23. Epub 2023 Sep 27. PubMed |
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