pWZL hygro H-Ras V12 Citations (16)

Originally described in: Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a.
Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW Cell. 1997 Mar 7. 88(5):593-602. PubMed Journal

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Articles Citing pWZL hygro H-Ras V12

Articles
Rictor phosphorylation on the Thr-1135 site does not require mammalian target of rapamycin complex 2. Boulbes D, Chen CH, Shaikenov T, Agarwal NK, Peterson TR, Addona TA, Keshishian H, Carr SA, Magnuson MA, Sabatini DM, Sarbassov dos D. Mol Cancer Res. 2010 Jun;8(6):896-906. doi: 10.1158/1541-7786.MCR-09-0409. Epub 2010 May 25. PubMed
Suppression of microRNA-9 by mutant EGFR signaling upregulates FOXP1 to enhance glioblastoma tumorigenicity. Gomez GG, Volinia S, Croce CM, Zanca C, Li M, Emnett R, Gutmann DH, Brennan CW, Furnari FB, Cavenee WK. Cancer Res. 2014 Mar 1;74(5):1429-39. doi: 10.1158/0008-5472.CAN-13-2117. Epub 2014 Jan 16. PubMed
c-Myb and C/EBPbeta regulate OPN and other senescence-associated secretory phenotype factors. Flanagan KC, Alspach E, Pazolli E, Parajuli S, Ren Q, Arthur LL, Tapia R, Stewart SA. Oncotarget. 2017 Dec 5;9(1):21-36. doi: 10.18632/oncotarget.22940. eCollection 2018 Jan 2. PubMed
Copper accumulation in senescent cells: Interplay between copper transporters and impaired autophagy. Masaldan S, Clatworthy SAS, Gamell C, Smith ZM, Francis PS, Denoyer D, Meggyesy PM, Fontaine S, Cater MA. Redox Biol. 2018 Jun;16:322-331. doi: 10.1016/j.redox.2018.03.007. Epub 2018 Mar 17. PubMed
Aneuploidy-inducing gene knockdowns overlap with cancer mutations and identify Orp3 as a B-cell lymphoma suppressor. Njeru SN, Kraus J, Meena JK, Lechel A, Katz SF, Kumar M, Knippschild U, Azoitei A, Wezel F, Bolenz C, Leithauser F, Gollowitzer A, Omrani O, Hoischen C, Koeberle A, Kestler HA, Gunes C, Rudolph KL. Oncogene. 2020 Feb;39(7):1445-1465. doi: 10.1038/s41388-019-1073-2. Epub 2019 Oct 28. PubMed
Investigating the duality of Inpp4b function in the cellular transformation of mouse fibroblasts. Mangialardi EM, Chen K, Salmon B, Vacher J, Salmena L. Oncotarget. 2019 Oct 29;10(59):6378-6390. doi: 10.18632/oncotarget.27293. eCollection 2019 Oct 29. PubMed
Reply to: Transformation of naked mole-rat cells. Zhao J, Tian X, Zhu Y, Zhang Z, Rydkina E, Yuan Y, Zhang H, Roy B, Cornwell A, Nevo E, Shang X, Huang R, Kristiansen K, Seluanov A, Fang X, Gorbunova V. Nature. 2020 Jul;583(7814):E8-E13. doi: 10.1038/s41586-020-2411-9. PubMed
Genomic retargeting of p53 and CTCF is associated with transcriptional changes during oncogenic HRas-induced transformation. Schwartz M, Portugez AS, Attia BZ, Tannenbaum M, Cohen L, Loza O, Chase E, Turman Y, Kaplan T, Salah Z, Hakim O. Commun Biol. 2020 Nov 25;3(1):696. doi: 10.1038/s42003-020-01398-y. PubMed
p53-intact cancers escape tumor suppression through loss of long noncoding RNA Dino. Marney CB, Anderson ES, Adnan M, Peng KL, Hu Y, Weinhold N, Schmitt AM. Cell Rep. 2021 Jun 29;35(13):109329. doi: 10.1016/j.celrep.2021.109329. PubMed
Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome. Kuzuoglu-Ozturk D, Hu Z, Rama M, Devericks E, Weiss J, Chiang GG, Worland ST, Brenner SE, Goodarzi H, Gilbert LA, Ruggero D. Cell Rep. 2021 Jun 29;35(13):109321. doi: 10.1016/j.celrep.2021.109321. PubMed
ZNF768 links oncogenic RAS to cellular senescence. Villot R, Poirier A, Bakan I, Boulay K, Fernandez E, Devillers R, Gama-Braga L, Tribouillard L, Gagne A, Duchesne E, Caron D, Berube JS, Berube JC, Coulombe Y, Orain M, Gelinas Y, Gobeil S, Bosse Y, Masson JY, Elowe S, Bilodeau S, Manem V, Joubert P, Mallette FA, Laplante M. Nat Commun. 2021 Aug 17;12(1):4841. doi: 10.1038/s41467-021-24932-w. PubMed
Transposon-triggered innate immune response confers cancer resistance to the blind mole rat. Zhao Y, Oreskovic E, Zhang Q, Lu Q, Gilman A, Lin YS, He J, Zheng Z, Lu JY, Lee J, Ke Z, Ablaeva J, Sweet MJ, Horvath S, Zhang Z, Nevo E, Seluanov A, Gorbunova V. Nat Immunol. 2021 Oct;22(10):1219-1230. doi: 10.1038/s41590-021-01027-8. Epub 2021 Sep 23. PubMed
Glioblastoma genetic drivers dictate the function of tumor-associated macrophages/microglia and responses to CSF1R inhibition. Rao R, Han R, Ogurek S, Xue C, Wu LM, Zhang L, Zhang L, Hu J, Phoenix TN, Waggoner SN, Lu QR. Neuro Oncol. 2022 Apr 1;24(4):584-597. doi: 10.1093/neuonc/noab228. PubMed
A Comparative Assessment of Replication Stress Markers in the Context of Telomerase. Meessen S, Najjar G, Azoitei A, Iben S, Bolenz C, Gunes C. Cancers (Basel). 2022 Apr 28;14(9). pii: cancers14092205. doi: 10.3390/cancers14092205. PubMed
Lysosomal control of senescence and inflammation through cholesterol partitioning. Roh K, Noh J, Kim Y, Jang Y, Kim J, Choi H, Lee Y, Ji M, Kang D, Kim MS, Paik MJ, Chung J, Kim JH, Kang C. Nat Metab. 2023 Mar;5(3):398-413. doi: 10.1038/s42255-023-00747-5. Epub 2023 Mar 2. PubMed
Loss of RAB25 Cooperates with Oncogenes in the Transformation of Human Mammary Epithelial Cells (HMECs) to Give Rise to Claudin-Low Tumors. Joshi P, Ayyagari V, Kandel S, Modur V, Iqbal MF, Robinson K, Gao J, Rao K. Biomed Res Int. 2024 May 20;2024:8544837. doi: 10.1155/2024/8544837. eCollection 2024. PubMed

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