scramble shRNA Citations (567)
Originally described in: Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.Sarbassov DD, Guertin DA, Ali SM, Sabatini DM Science 2005 Feb 18;307(5712):1098-101. PubMed Journal
Articles Citing scramble shRNA
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| Human cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexes. Kudchodkar SB, Yu Y, Maguire TG, Alwine JC. Proc Natl Acad Sci U S A. 2006 Sep 19. 103(38):14182-7. PubMed |
PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding.
Wang L, Harris TE, Roth RA, Lawrence JC.
J Biol Chem. 2007 Jul 6. 282(27):20036-44.
PubMed
Associated Plasmids |
| mTORC2 activity is elevated in gliomas and promotes growth and cell motility via overexpression of rictor. Masri J, Bernath A, Martin J, Jo OD, Vartanian R, Funk A, Gera J. Cancer Res. 2007 Dec 15. 67(24):11712-20. PubMed |
| The interferon response inhibits HIV particle production by induction of TRIM22. Barr SD, Smiley JR, Bushman FD. PLoS Pathog. 2008 Feb 29;4(2):e1000007. doi: 10.1371/journal.ppat.1000007. PubMed |
| XRCC1 protects against the lethality of induced oxidative DNA damage in nondividing neural cells. Kulkarni A, McNeill DR, Gleichmann M, Mattson MP, Wilson DM 3rd. Nucleic Acids Res. 2008 Sep;36(15):5111-21. doi: 10.1093/nar/gkn480. Epub 2008 Aug 5. PubMed |
| Tumor-growth-promoting cyclooxygenase-2 prostaglandin E2 pathway provides medulloblastoma therapeutic targets. Baryawno N, Sveinbjornsson B, Eksborg S, Orrego A, Segerstrom L, Oqvist CO, Holm S, Gustavsson B, Kagedal B, Kogner P, Johnsen JI. Neuro Oncol. 2008 Oct;10(5):661-74. doi: 10.1215/15228517-2008-035. Epub 2008 Aug 20. PubMed |
| COP1 functions as a FoxO1 ubiquitin E3 ligase to regulate FoxO1-mediated gene expression. Kato S, Ding J, Pisck E, Jhala US, Du K. J Biol Chem. 2008 Dec 19;283(51):35464-73. doi: 10.1074/jbc.M801011200. Epub 2008 Sep 24. PubMed |
| Timeless Maintains Genomic Stability and Suppresses Sister Chromatid Exchange during Unperturbed DNA Replication. Urtishak KA, Smith KD, Chanoux RA, Greenberg RA, Johnson FB, Brown EJ. J Biol Chem. 2009 Mar 27;284(13):8777-85. doi: 10.1074/jbc.M806103200. Epub 2008 Dec 28. PubMed |
| A myelopoiesis-associated regulatory intergenic noncoding RNA transcript within the human HOXA cluster. Zhang X, Lian Z, Padden C, Gerstein MB, Rozowsky J, Snyder M, Gingeras TR, Kapranov P, Weissman SM, Newburger PE. Blood. 2009 Mar 12;113(11):2526-34. doi: 10.1182/blood-2008-06-162164. Epub 2009 Jan 14. PubMed |
| Functional involvement of RINF, retinoid-inducible nuclear factor (CXXC5), in normal and tumoral human myelopoiesis. Pendino F, Nguyen E, Jonassen I, Dysvik B, Azouz A, Lanotte M, Segal-Bendirdjian E, Lillehaug JR. Blood. 2009 Apr 2;113(14):3172-81. doi: 10.1182/blood-2008-07-170035. Epub 2009 Jan 30. PubMed |
| TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2. Copp J, Manning G, Hunter T. Cancer Res. 2009 Mar 1. 69(5):1821-7. PubMed |
| The transcription of FOXO genes is stimulated by FOXO3 and repressed by growth factors. Essaghir A, Dif N, Marbehant CY, Coffer PJ, Demoulin JB. J Biol Chem. 2009 Apr 17;284(16):10334-42. doi: 10.1074/jbc.M808848200. Epub 2009 Feb 24. PubMed |
| Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis. Barbero S, Mielgo A, Torres V, Teitz T, Shields DJ, Mikolon D, Bogyo M, Barila D, Lahti JM, Schlaepfer D, Stupack DG. Cancer Res. 2009 May 1;69(9):3755-63. doi: 10.1158/0008-5472.CAN-08-3937. Epub 2009 Apr 21. PubMed |
| In vivo genetic manipulation of the rat trophoblast cell lineage using lentiviral vector delivery. Lee DS, Rumi MA, Konno T, Soares MJ. Genesis. 2009 Jul;47(7):433-9. doi: 10.1002/dvg.20518. PubMed |
| Site-specific mTOR phosphorylation promotes mTORC1-mediated signaling and cell growth. Acosta-Jaquez HA, Keller JA, Foster KG, Ekim B, Soliman GA, Ballif BA, Fingar DC. Mol Cell Biol. 2009 Jun 1. ():. PubMed |
| Ribavirin enhances interferon signaling via stimulation of mTOR and p53 activities. Su WC, Liu WL, Cheng CW, Chou YB, Hung KH, Huang WH, Wu CL, Li YT, Shiau AL, Lai MY. FEBS Lett. 2009 Sep 3;583(17):2793-8. doi: 10.1016/j.febslet.2009.07.027. Epub 2009 Jul 18. PubMed |
| Activated Abl kinase inhibits oncogenic transforming growth factor-beta signaling and tumorigenesis in mammary tumors. Allington TM, Galliher-Beckley AJ, Schiemann WP. FASEB J. 2009 Dec;23(12):4231-43. doi: 10.1096/fj.09-138412. Epub 2009 Aug 18. PubMed |
| Nitric oxide induces cell death by regulating anti-apoptotic BCL-2 family members. Snyder CM, Shroff EH, Liu J, Chandel NS. PLoS One. 2009 Sep 21;4(9):e7059. doi: 10.1371/journal.pone.0007059. PubMed |
| G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway. Chen M, Philipp M, Wang J, Premont RT, Garrison TR, Caron MG, Lefkowitz RJ, Chen W. J Biol Chem. 2009 Dec 11. 284(50):35040-8. PubMed |
| Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesis. Smith KD, Fu MA, Brown EJ. J Cell Biol. 2009 Oct 5. 187(1):15-23. PubMed |
| Rab5 mediates caspase-8-promoted cell motility and metastasis. Torres VA, Mielgo A, Barbero S, Hsiao R, Wilkins JA, Stupack DG. Mol Biol Cell. 2010 Jan 15;21(2):369-76. doi: 10.1091/mbc.E09-09-0769. Epub 2009 Nov 18. PubMed |
| Aire regulates the expression of differentiation-associated genes and self-renewal of embryonic stem cells. Gu B, Zhang J, Chen Q, Tao B, Wang W, Zhou Y, Chen L, Liu Y, Zhang M. Biochem Biophys Res Commun. 2010 Apr 2. 394(2):418-23. PubMed |
| Functional analysis of the Cdk7.cyclin H.Mat1 complex in mouse embryonic stem cells and embryos. Patel SA, Simon MC. J Biol Chem. 2010 May 14;285(20):15587-98. doi: 10.1074/jbc.M109.081687. Epub 2010 Mar 15. PubMed |
| Slug inhibits proliferation of human prostate cancer cells via downregulation of cyclin D1 expression. Liu J, Uygur B, Zhang Z, Shao L, Romero D, Vary C, Ding Q, Wu WS. Prostate. 2010 Dec 1;70(16):1768-77. doi: 10.1002/pros.21213. PubMed |
| The human WRN and BLM RecQ helicases differentially regulate cell proliferation and survival after chemotherapeutic DNA damage. Mao FJ, Sidorova JM, Lauper JM, Emond MJ, Monnat RJ. Cancer Res. 2010 Aug 15;70(16):6548-55. doi: 10.1158/0008-5472.CAN-10-0475. Epub 2010 Jul 27. PubMed |
| Targeting TORC2 in multiple myeloma with a new mTOR kinase inhibitor. Hoang B, Frost P, Shi Y, Belanger E, Benavides A, Pezeshkpour G, Cappia S, Guglielmelli T, Gera J, Lichtenstein A. Blood. 2010 Nov 25;116(22):4560-8. doi: 10.1182/blood-2010-05-285726. Epub 2010 Aug 4. PubMed |
| Long-term IGF-I exposure decreases autophagy and cell viability. Bitto A, Lerner C, Torres C, Roell M, Malaguti M, Perez V, Lorenzini A, Hrelia S, Ikeno Y, Matzko ME, McCarter R, Sell C. PLoS One. 2010 Sep 7;5(9):e12592. doi: 10.1371/journal.pone.0012592. PubMed |
| Syntaxin 3 is necessary for cAMP- and cGMP-regulated exocytosis of CFTR: implications for enterotoxigenic diarrhea. Collaco A, Marathe J, Kohnke H, Kravstov D, Ameen N. Am J Physiol Cell Physiol. 2010 Dec;299(6):C1450-60. doi: 10.1152/ajpcell.00029.2010. Epub 2010 Sep 15. PubMed |
| Dual-specificity phosphatase 23 mediates GCM1 dephosphorylation and activation. Lin FY, Chang CW, Cheong ML, Chen HC, Lee DY, Chang GD, Chen H. Nucleic Acids Res. 2011 Feb;39(3):848-61. doi: 10.1093/nar/gkq838. Epub 2010 Sep 19. PubMed |
| Ku80 facilitates chromatin binding of the telomere binding protein, TRF2. Fink LS, Lerner CA, Torres PF, Sell C. Cell Cycle. 2010 Sep 15;9(18):3798-806. Epub 2010 Sep 25. PubMed |
| Cytokinesis failure occurs in Fanconi anemia pathway-deficient murine and human bone marrow hematopoietic cells. Vinciguerra P, Godinho SA, Parmar K, Pellman D, D'Andrea AD. J Clin Invest. 2010 Nov;120(11):3834-42. doi: 10.1172/JCI43391. PubMed |
| A WD-repeat protein stabilizes ORC binding to chromatin. Shen Z, Sathyan KM, Geng Y, Zheng R, Chakraborty A, Freeman B, Wang F, Prasanth KV, Prasanth SG. Mol Cell. 2010 Oct 8;40(1):99-111. doi: 10.1016/j.molcel.2010.09.021. PubMed |
| In vitro genetic analysis of an erythrocyte determinant of malaria infection. Bei AK, Brugnara C, Duraisingh MT. J Infect Dis. 2010 Dec 1;202(11):1722-7. doi: 10.1086/657157. Epub 2010 Oct 19. PubMed |
| Epithelial cell death is an important contributor to oxidant-mediated acute lung injury. Budinger GR, Mutlu GM, Urich D, Soberanes S, Buccellato LJ, Hawkins K, Chiarella SE, Radigan KA, Eisenbart J, Agrawal H, Berkelhamer S, Hekimi S, Zhang J, Perlman H, Schumacker PT, Jain M, Chandel NS. Am J Respir Crit Care Med. 2011 Apr 15;183(8):1043-54. doi: 10.1164/rccm.201002-0181OC. Epub 2010 Oct 19. PubMed |
| Podoplanin associates with CD44 to promote directional cell migration. Martin-Villar E, Fernandez-Munoz B, Parsons M, Yurrita MM, Megias D, Perez-Gomez E, Jones GE, Quintanilla M. Mol Biol Cell. 2010 Dec;21(24):4387-99. doi: 10.1091/mbc.E10-06-0489. Epub 2010 Oct 20. PubMed |
| Bif-1 regulates Atg9 trafficking by mediating the fission of Golgi membranes during autophagy. Takahashi Y, Meyerkord CL, Hori T, Runkle K, Fox TE, Kester M, Loughran TP, Wang HG. Autophagy. 2011 Jan . 7(1):61-73. PubMed |
| Lysyl oxidase-like-2 (LOXL2) is a major isoform in chondrocytes and is critically required for differentiation. Iftikhar M, Hurtado P, Bais MV, Wigner N, Stephens DN, Gerstenfeld LC, Trackman PC. J Biol Chem. 2011 Jan 14;286(2):909-18. doi: 10.1074/jbc.M110.155622. Epub 2010 Nov 11. PubMed |
| Prolylcarboxypeptidase regulates proliferation, autophagy, and resistance to 4-hydroxytamoxifen-induced cytotoxicity in estrogen receptor-positive breast cancer cells. Duan L, Motchoulski N, Danzer B, Davidovich I, Shariat-Madar Z, Levenson VV. J Biol Chem. 2011 Jan 28;286(4):2864-76. doi: 10.1074/jbc.M110.143271. Epub 2010 Nov 17. PubMed |
| The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNA. Nowak U, Matthews AJ, Zheng S, Chaudhuri J. Nat Immunol. 2011 Feb;12(2):160-6. doi: 10.1038/ni.1977. Epub 2010 Dec 26. PubMed |
| Cullin-4A.DNA damage-binding protein 1 E3 ligase complex targets tumor suppressor RASSF1A for degradation during mitosis. Jiang L, Rong R, Sheikh MS, Huang Y. J Biol Chem. 2011 Mar 4;286(9):6971-8. doi: 10.1074/jbc.M110.186494. Epub 2011 Jan 4. PubMed |
| Scavenger receptor WC1 contributes to the gammadelta T cell response to Leptospira. Wang F, Herzig CT, Chen C, Hsu H, Baldwin CL, Telfer JC. Mol Immunol. 2011 Mar;48(6-7):801-9. doi: 10.1016/j.molimm.2010.12.001. Epub 2011 Jan 11. PubMed |
| Akt1 deletion prevents lung tumorigenesis by mutant K-ras. Hollander MC, Maier CR, Hobbs EA, Ashmore AR, Linnoila RI, Dennis PA. Oncogene. 2011 Apr 14;30(15):1812-21. doi: 10.1038/onc.2010.556. Epub 2011 Jan 17. PubMed |
| Therapy mediated by mitophagy abrogates tumor progression. Gargini R, Garcia-Escudero V, Izquierdo M. Autophagy. 2011 May;7(5):466-76. Epub 2011 May 1. PubMed |
| ROS signaling by NOX4 drives fibroblast-to-myofibroblast differentiation in the diseased prostatic stroma. Sampson N, Koziel R, Zenzmaier C, Bubendorf L, Plas E, Jansen-Durr P, Berger P. Mol Endocrinol. 2011 Mar;25(3):503-15. doi: 10.1210/me.2010-0340. Epub 2011 Jan 27. PubMed |
| The adaptor protein AMOT promotes the proliferation of mammary epithelial cells via the prolonged activation of the extracellular signal-regulated kinases. Ranahan WP, Han Z, Smith-Kinnaman W, Nabinger SC, Heller B, Herbert BS, Chan R, Wells CD. Cancer Res. 2011 Mar 15;71(6):2203-11. doi: 10.1158/0008-5472.CAN-10-1995. Epub 2011 Feb 1. PubMed |
| JNK signaling promotes intestinal tumorigenesis through activation of mTOR complex 1 in Apc(Delta716) mice. Fujishita T, Aoki M, Taketo MM. Gastroenterology. 2011 May;140(5):1556-63.e6. doi: 10.1053/j.gastro.2011.02.007. Epub 2011 Feb 12. PubMed |
| SirT3 suppresses hypoxia inducible factor 1alpha and tumor growth by inhibiting mitochondrial ROS production. Bell EL, Emerling BM, Ricoult SJ, Guarente L. Oncogene. 2011 Jun 30;30(26):2986-96. doi: 10.1038/onc.2011.37. Epub 2011 Feb 28. PubMed |
| Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells. Zlatic SA, Tornieri K, L'Hernault SW, Faundez V. Mol Biol Cell. 2011 May 15;22(10):1699-715. doi: 10.1091/mbc.E10-10-0799. Epub 2011 Mar 16. PubMed |
| Phosphorylation of p27Kip1 by JAK2 directly links cytokine receptor signaling to cell cycle control. Jakel H, Weinl C, Hengst L. Oncogene. 2011 Aug 11;30(32):3502-12. doi: 10.1038/onc.2011.68. Epub 2011 Mar 21. PubMed |
| Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development. Kawazu M, Saso K, Tong KI, McQuire T, Goto K, Son DO, Wakeham A, Miyagishi M, Mak TW, Okada H. PLoS One. 2011 Mar 18;6(3):e17830. doi: 10.1371/journal.pone.0017830. PubMed |
| Depletion of the histone chaperone tNASP inhibits proliferation and induces apoptosis in prostate cancer PC-3 cells. Alekseev OM, Richardson RT, Tsuruta JK, O'Rand MG. Reprod Biol Endocrinol. 2011 Apr 16;9:50. doi: 10.1186/1477-7827-9-50. PubMed |
| Phosphoproteomic screen identifies potential therapeutic targets in melanoma. Tworkoski K, Singhal G, Szpakowski S, Zito CI, Bacchiocchi A, Muthusamy V, Bosenberg M, Krauthammer M, Halaban R, Stern DF. Mol Cancer Res. 2011 Jun;9(6):801-12. doi: 10.1158/1541-7786.MCR-10-0512. Epub 2011 Apr 26. PubMed |
| The human T-cell leukemia virus type 1 oncoprotein tax controls forkhead box O4 activity through degradation by the proteasome. Oteiza A, Mechti N. J Virol. 2011 Jul;85(13):6480-91. doi: 10.1128/JVI.00036-11. Epub 2011 Apr 27. PubMed |
| mTOR kinase domain phosphorylation promotes mTORC1 signaling, cell growth, and cell cycle progression. Ekim B, Magnuson B, Acosta-Jaquez HA, Keller JA, Feener EP, Fingar DC. Mol Cell Biol. 2011 Jul;31(14):2787-801. doi: 10.1128/MCB.05437-11. Epub 2011 May 16. PubMed |
| Deptor knockdown enhances mTOR Activity and protein synthesis in myocytes and ameliorates disuse muscle atrophy. Kazi AA, Hong-Brown L, Lang SM, Lang CH. Mol Med. 2011 Sep-Oct;17(9-10):925-36. doi: 10.2119/molmed.2011.00070. Epub 2011 May 19. PubMed |
Snail1, Snail2, and E47 promote mammary epithelial branching morphogenesis.
Lee K, Gjorevski N, Boghaert E, Radisky DC, Nelson CM.
EMBO J. 2011 May 24;30(13):2662-74. doi: 10.1038/emboj.2011.159.
PubMed
Associated Plasmids |
| Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1. Glauser L, Sonnay S, Stafa K, Moore DJ. J Neurochem. 2011 Aug;118(4):636-45. doi: 10.1111/j.1471-4159.2011.07318.x. Epub 2011 Jun 6. PubMed |
Willin/FRMD6 expression activates the Hippo signaling pathway kinases in mammals and antagonizes oncogenic YAP.
Angus L, Moleirinho S, Herron L, Sinha A, Zhang X, Niestrata M, Dholakia K, Prystowsky MB, Harvey KF, Reynolds PA, Gunn-Moore FJ.
Oncogene. 2012 Jan 12;31(2):238-50. doi: 10.1038/onc.2011.224. Epub 2011 Jun 13.
PubMed
Associated Plasmids |
| Transcription factor TEAD4 regulates expression of myogenin and the unfolded protein response genes during C2C12 cell differentiation. Benhaddou A, Keime C, Ye T, Morlon A, Michel I, Jost B, Mengus G, Davidson I. Cell Death Differ. 2012 Feb;19(2):220-31. doi: 10.1038/cdd.2011.87. Epub 2011 Jun 24. PubMed |
| Peroxisome-proliferator-activated receptor gamma coactivator 1 alpha contributes to dysmyelination in experimental models of Huntington's disease. Xiang Z, Valenza M, Cui L, Leoni V, Jeong HK, Brilli E, Zhang J, Peng Q, Duan W, Reeves SA, Cattaneo E, Krainc D. J Neurosci. 2011 Jun 29;31(26):9544-53. doi: 10.1523/JNEUROSCI.1291-11.2011. PubMed |
| Hypoxia leads to Na,K-ATPase downregulation via Ca(2+) release-activated Ca(2+) channels and AMPK activation. Gusarova GA, Trejo HE, Dada LA, Briva A, Welch LC, Hamanaka RB, Mutlu GM, Chandel NS, Prakriya M, Sznajder JI. Mol Cell Biol. 2011 Sep;31(17):3546-56. doi: 10.1128/MCB.05114-11. Epub 2011 Jul 5. PubMed |
| The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML. Zhou J, Bi C, Cheong LL, Mahara S, Liu SC, Tay KG, Koh TL, Yu Q, Chng WJ. Blood. 2011 Sep 8;118(10):2830-9. doi: 10.1182/blood-2010-07-294827. Epub 2011 Jul 6. PubMed |
| A novel cyclic AMP/Epac1/CaMKI signaling cascade promotes GCM1 desumoylation and placental cell fusion. Chang CW, Chang GD, Chen H. Mol Cell Biol. 2011 Sep;31(18):3820-31. doi: 10.1128/MCB.05582-11. Epub 2011 Jul 26. PubMed |
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity.
Kofoed EM, Vance RE.
Nature. 2011 Aug 28;477(7366):592-5. doi: 10.1038/nature10394.
PubMed
Associated Plasmids |
| Dickkopf-3 maintains the PANC-1 human pancreatic tumor cells in a dedifferentiated state. Zenzmaier C, Hermann M, Hengster P, Berger P. Int J Oncol. 2012 Jan;40(1):40-6. doi: 10.3892/ijo.2011.1180. Epub 2011 Aug 29. PubMed |
| Distinct developmental ground states of epiblast stem cell lines determine different pluripotency features. Bernemann C, Greber B, Ko K, Sterneckert J, Han DW, Arauzo-Bravo MJ, Scholer HR. Stem Cells. 2011 Oct;29(10):1496-503. doi: 10.1002/stem.709. PubMed |
| 53BP1 contributes to a robust genomic stability in human fibroblasts. Fink LS, Roell M, Caiazza E, Lerner C, Stamato T, Hrelia S, Lorenzini A, Sell C. Aging (Albany NY). 2011 Sep;3(9):836-45. PubMed |
| CHD5, a brain-specific paralog of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genes. Potts RC, Zhang P, Wurster AL, Precht P, Mughal MR, Wood WH 3rd, Zhang Y, Becker KG, Mattson MP, Pazin MJ. PLoS One. 2011;6(9):e24515. doi: 10.1371/journal.pone.0024515. Epub 2011 Sep 13. PubMed |
| FOSL1 is integral to establishing the maternal-fetal interface. Kent LN, Rumi MA, Kubota K, Lee DS, Soares MJ. Mol Cell Biol. 2011 Dec;31(23):4801-13. doi: 10.1128/MCB.05780-11. Epub 2011 Sep 26. PubMed |
| Inhibition of mTOR kinase by AZD8055 can antagonize chemotherapy-induced cell death through autophagy induction and down-regulation of p62/sequestosome 1. Huang S, Yang ZJ, Yu C, Sinicrope FA. J Biol Chem. 2011 Nov 18;286(46):40002-12. doi: 10.1074/jbc.M111.297432. Epub 2011 Sep 23. PubMed |
| c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells. Waldron T, De Dominici M, Soliera AR, Audia A, Iacobucci I, Lonetti A, Martinelli G, Zhang Y, Martinez R, Hyslop T, Bender TP, Calabretta B. Leukemia. 2012 Apr;26(4):644-53. doi: 10.1038/leu.2011.264. Epub 2011 Sep 30. PubMed |
| O(2) regulates skeletal muscle progenitor differentiation through phosphatidylinositol 3-kinase/AKT signaling. Majmundar AJ, Skuli N, Mesquita RC, Kim MN, Yodh AG, Nguyen-McCarty M, Simon MC. Mol Cell Biol. 2012 Jan;32(1):36-49. doi: 10.1128/MCB.05857-11. Epub 2011 Oct 17. PubMed |
| Disruption of Wnt planar cell polarity signaling by aberrant accumulation of the MetAP-2 substrate Rab37. Sundberg TB, Darricarrere N, Cirone P, Li X, McDonald L, Mei X, Westlake CJ, Slusarski DC, Beynon RJ, Crews CM. Chem Biol. 2011 Oct 28;18(10):1300-11. doi: 10.1016/j.chembiol.2011.07.020. PubMed |
| SLUG promotes prostate cancer cell migration and invasion via CXCR4/CXCL12 axis. Uygur B, Wu WS. Mol Cancer. 2011 Nov 10;10:139. doi: 10.1186/1476-4598-10-139. PubMed |
Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum.
Crosnier C, Bustamante LY, Bartholdson SJ, Bei AK, Theron M, Uchikawa M, Mboup S, Ndir O, Kwiatkowski DP, Duraisingh MT, Rayner JC, Wright GJ.
Nature. 2011 Nov 9;480(7378):534-7. doi: 10.1038/nature10606.
PubMed
Associated Plasmids |
| Optimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1. Orthwein A, Zahn A, Methot SP, Godin D, Conticello SG, Terada K, Di Noia JM. EMBO J. 2012 Feb 1;31(3):679-91. doi: 10.1038/emboj.2011.417. Epub 2011 Nov 15. PubMed |
| FGF signalling inhibits neural induction in human embryonic stem cells. Greber B, Coulon P, Zhang M, Moritz S, Frank S, Muller-Molina AJ, Arauzo-Bravo MJ, Han DW, Pape HC, Scholer HR. EMBO J. 2011 Nov 15;30(24):4874-84. doi: 10.1038/emboj.2011.407. PubMed |
| Ran is a potential therapeutic target for cancer cells with molecular changes associated with activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK pathways. Yuen HF, Chan KK, Grills C, Murray JT, Platt-Higgins A, Eldin OS, O'Byrne K, Janne P, Fennell DA, Johnston PG, Rudland PS, El-Tanani M. Clin Cancer Res. 2012 Jan 15;18(2):380-91. doi: 10.1158/1078-0432.CCR-11-2035. Epub 2011 Nov 16. PubMed |
| Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag. Woods MW, Kelly JN, Hattlmann CJ, Tong JG, Xu LS, Coleman MD, Quest GR, Smiley JR, Barr SD. Retrovirology. 2011 Nov 17;8:95. doi: 10.1186/1742-4690-8-95. PubMed |
| Pygo2 regulates histone gene expression and H3 K56 acetylation in human mammary epithelial cells. Gu B, Watanabe K, Dai X. Cell Cycle. 2012 Jan 1;11(1):79-87. doi: 10.4161/cc.11.1.18402. Epub 2012 Jan 1. PubMed |
| Orai1-mediated calcium entry plays a critical role in osteoclast differentiation and function by regulating activation of the transcription factor NFATc1. Hwang SY, Putney JW. FASEB J. 2012 Apr;26(4):1484-92. doi: 10.1096/fj.11-194399. Epub 2011 Dec 23. PubMed |
| LRRK2 inhibition attenuates microglial inflammatory responses. Moehle MS, Webber PJ, Tse T, Sukar N, Standaert DG, DeSilva TM, Cowell RM, West AB. J Neurosci. 2012 Feb 1;32(5):1602-11. doi: 10.1523/JNEUROSCI.5601-11.2012. PubMed |
| Regulated clearance of histone deacetylase 3 protects independent formation of nuclear receptor corepressor complexes. Guo C, Gow CH, Li Y, Gardner A, Khan S, Zhang J. J Biol Chem. 2012 Apr 6;287(15):12111-20. doi: 10.1074/jbc.M111.327023. Epub 2012 Feb 15. PubMed |
| Negative regulation of RhoA translation and signaling by hnRNP-Q1 affects cellular morphogenesis. Xing L, Yao X, Williams KR, Bassell GJ. Mol Biol Cell. 2012 Apr;23(8):1500-9. doi: 10.1091/mbc.E11-10-0867. Epub 2012 Feb 22. PubMed |
| The Amotl2 gene inhibits Wnt/beta-catenin signaling and regulates embryonic development in zebrafish. Li Z, Wang Y, Zhang M, Xu P, Huang H, Wu D, Meng A. J Biol Chem. 2012 Apr 13;287(16):13005-15. doi: 10.1074/jbc.M112.347419. Epub 2012 Feb 23. PubMed |
| Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis. Young MM, Takahashi Y, Khan O, Park S, Hori T, Yun J, Sharma AK, Amin S, Hu CD, Zhang J, Kester M, Wang HG. J Biol Chem. 2012 Apr 6;287(15):12455-68. doi: 10.1074/jbc.M111.309104. Epub 2012 Feb 23. PubMed |
| GTPase activity and neuronal toxicity of Parkinson's disease-associated LRRK2 is regulated by ArfGAP1. Stafa K, Trancikova A, Webber PJ, Glauser L, West AB, Moore DJ. PLoS Genet. 2012;8(2):e1002526. doi: 10.1371/journal.pgen.1002526. Epub 2012 Feb 9. PubMed |
| Quantitative proteomic and genetic analyses of the schizophrenia susceptibility factor dysbindin identify novel roles of the biogenesis of lysosome-related organelles complex 1. Gokhale A, Larimore J, Werner E, So L, Moreno-De-Luca A, Lese-Martin C, Lupashin VV, Smith Y, Faundez V. J Neurosci. 2012 Mar 14;32(11):3697-711. doi: 10.1523/JNEUROSCI.5640-11.2012. PubMed |
| Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis. Sonveaux P, Copetti T, De Saedeleer CJ, Vegran F, Verrax J, Kennedy KM, Moon EJ, Dhup S, Danhier P, Frerart F, Gallez B, Ribeiro A, Michiels C, Dewhirst MW, Feron O. PLoS One. 2012;7(3):e33418. doi: 10.1371/journal.pone.0033418. Epub 2012 Mar 13. PubMed |
| Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons. Huang WC, Xiao S, Huang F, Harfe BD, Jan YN, Jan LY. Neuron. 2012 Apr 12;74(1):179-92. doi: 10.1016/j.neuron.2012.01.033. PubMed |
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KIBRA exhibits MST-independent functional regulation of the Hippo signaling pathway in mammals.
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| Inhibiting adipose tissue lipogenesis reprograms thermogenesis and PPARgamma activation to decrease diet-induced obesity. Lodhi IJ, Yin L, Jensen-Urstad AP, Funai K, Coleman T, Baird JH, El Ramahi MK, Razani B, Song H, Fu-Hsu F, Turk J, Semenkovich CF. Cell Metab. 2012 Aug 8;16(2):189-201. PubMed |
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| Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells. De Saedeleer CJ, Copetti T, Porporato PE, Verrax J, Feron O, Sonveaux P. PLoS One. 2012;7(10):e46571. doi: 10.1371/journal.pone.0046571. Epub 2012 Oct 17. PubMed |
| HIF-independent role of prolyl hydroxylases in the cellular response to amino acids. Duran RV, MacKenzie ED, Boulahbel H, Frezza C, Heiserich L, Tardito S, Bussolati O, Rocha S, Hall MN, Gottlieb E. Oncogene. 2013 Sep 19;32(38):4549-56. doi: 10.1038/onc.2012.465. Epub 2012 Oct 22. PubMed |
| NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-theta and reactive oxygen species. Giambra V, Jenkins CR, Wang H, Lam SH, Shevchuk OO, Nemirovsky O, Wai C, Gusscott S, Chiang MY, Aster JC, Humphries RK, Eaves C, Weng AP. Nat Med. 2012 Nov;18(11):1693-8. doi: 10.1038/nm.2960. Epub 2012 Oct 21. PubMed |
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| Resistance to hypoxia-induced, BNIP3-mediated cell death contributes to an increase in a CD133-positive cell population in human glioblastomas in vitro. Kahlert UD, Maciaczyk D, Dai F, Claus R, Firat E, Doostkam S, Bogiel T, Carro MS, Dobrossy M, Herold-Mende C, Niedermann G, Prinz M, Nikkhah G, Maciaczyk J. J Neuropathol Exp Neurol. 2012 Dec;71(12):1086-99. doi: 10.1097/NEN.0b013e3182772d83. PubMed |
| Hypoxia-inducible factor 1-alpha induces miR-210 in normoxic differentiating myoblasts. Cicchillitti L, Di Stefano V, Isaia E, Crimaldi L, Fasanaro P, Ambrosino V, Antonini A, Capogrossi MC, Gaetano C, Piaggio G, Martelli F. J Biol Chem. 2012 Dec 28;287(53):44761-71. doi: 10.1074/jbc.M112.421255. Epub 2012 Nov 12. PubMed |
| RECQL5 plays co-operative and complementary roles with WRN syndrome helicase. Popuri V, Huang J, Ramamoorthy M, Tadokoro T, Croteau DL, Bohr VA. Nucleic Acids Res. 2013 Jan;41(2):881-99. doi: 10.1093/nar/gks1134. Epub 2012 Nov 23. PubMed |
| The phosphatase-transcription activator EYA1 is targeted by anaphase-promoting complex/Cdh1 for degradation at M-to-G1 transition. Sun J, Karoulia Z, Wong EY, Ahmed M, Itoh K, Xu PX. Mol Cell Biol. 2013 Mar;33(5):927-36. doi: 10.1128/MCB.01516-12. Epub 2012 Dec 21. PubMed |
| Upregulated autophagy protects cardiomyocytes from oxidative stress-induced toxicity. Dutta D, Xu J, Kim JS, Dunn WA Jr, Leeuwenburgh C. Autophagy. 2013 Mar;9(3):328-44. doi: 10.4161/auto.22971. Epub 2013 Jan 8. PubMed |
| Up-regulation of MBD1 promotes pancreatic cancer cell epithelial-mesenchymal transition and invasion by epigenetic down-regulation of E-cadherin. Xu J, Zhu W, Xu W, Yao W, Zhang B, Xu Y, Ji S, Liu C, Long J, Ni Q, Yu X. Curr Mol Med. 2013 Mar;13(3):387-400. PubMed |
| Inhibition of TWIST1 leads to activation of oncogene-induced senescence in oncogene-driven non-small cell lung cancer. Burns TF, Dobromilskaya I, Murphy SC, Gajula RP, Thiyagarajan S, Chatley SN, Aziz K, Cho YJ, Tran PT, Rudin CM. Mol Cancer Res. 2013 Apr;11(4):329-38. doi: 10.1158/1541-7786.MCR-12-0456. Epub 2013 Jan 30. PubMed |
| Rheb activation in subventricular zone progenitors leads to heterotopia, ectopic neuronal differentiation, and rapamycin-sensitive olfactory micronodules and dendrite hypertrophy of newborn neurons. Lafourcade CA, Lin TV, Feliciano DM, Zhang L, Hsieh LS, Bordey A. J Neurosci. 2013 Feb 6;33(6):2419-31. doi: 10.1523/JNEUROSCI.1840-12.2013. PubMed |
| mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state. Cang C, Zhou Y, Navarro B, Seo YJ, Aranda K, Shi L, Battaglia-Hsu S, Nissim I, Clapham DE, Ren D. Cell. 2013 Feb 14;152(4):778-90. doi: 10.1016/j.cell.2013.01.023. Epub 2013 Feb 7. PubMed |
| The Angelman syndrome protein Ube3a/E6AP is required for Golgi acidification and surface protein sialylation. Condon KH, Ho J, Robinson CG, Hanus C, Ehlers MD. J Neurosci. 2013 Feb 27;33(9):3799-814. doi: 10.1523/JNEUROSCI.1930-11.2013. PubMed |
| Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer. Zinn RL, Gardner EE, Dobromilskaya I, Murphy S, Marchionni L, Hann CL, Rudin CM. Mol Cancer. 2013 Mar 2;12:16. doi: 10.1186/1476-4598-12-16. PubMed |
| Developmentally programmed 3' CpG island methylation confers tissue- and cell-type-specific transcriptional activation. Yu DH, Ware C, Waterland RA, Zhang J, Chen MH, Gadkari M, Kunde-Ramamoorthy G, Nosavanh LM, Shen L. Mol Cell Biol. 2013 May;33(9):1845-58. doi: 10.1128/MCB.01124-12. Epub 2013 Mar 4. PubMed |
| The TBC1D15 oncoprotein controls stem cell self-renewal through destabilization of the Numb-p53 complex. Feldman DE, Chen C, Punj V, Machida K. PLoS One. 2013;8(2):e57312. doi: 10.1371/journal.pone.0057312. Epub 2013 Feb 27. PubMed |
| Canonical Wnt signaling induces BMP-4 to specify slow myofibrogenesis of fetal myoblasts. Kuroda K, Kuang S, Taketo MM, Rudnicki MA. Skelet Muscle. 2013 Mar 5;3(1):5. doi: 10.1186/2044-5040-3-5. PubMed |
| Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation. Klauke K, Radulovic V, Broekhuis M, Weersing E, Zwart E, Olthof S, Ritsema M, Bruggeman S, Wu X, Helin K, Bystrykh L, de Haan G. Nat Cell Biol. 2013 Apr;15(4):353-62. doi: 10.1038/ncb2701. Epub 2013 Mar 17. PubMed |
| PQBP1, a factor linked to intellectual disability, affects alternative splicing associated with neurite outgrowth. Wang Q, Moore MJ, Adelmant G, Marto JA, Silver PA. Genes Dev. 2013 Mar 15;27(6):615-26. doi: 10.1101/gad.212308.112. PubMed |
| Amot130 adapts atrophin-1 interacting protein 4 to inhibit yes-associated protein signaling and cell growth. Adler JJ, Heller BL, Bringman LR, Ranahan WP, Cocklin RR, Goebl MG, Oh M, Lim HS, Ingham RJ, Wells CD. J Biol Chem. 2013 May 24;288(21):15181-93. doi: 10.1074/jbc.M112.446534. Epub 2013 Apr 5. PubMed |
| Silencing of MBD1 reverses pancreatic cancer therapy resistance through inhibition of DNA damage repair. Xu J, Zhu W, Xu W, Cui X, Chen L, Ji S, Qin Y, Yao W, Liu L, Liu C, Long J, Li M, Yu X. Int J Oncol. 2013 Jun;42(6):2046-52. doi: 10.3892/ijo.2013.1901. Epub 2013 Apr 16. PubMed |
| mTOR inhibitors radiosensitize PTEN-deficient non-small-cell lung cancer cells harboring an EGFR activating mutation by inducing autophagy. Kim EJ, Jeong JH, Bae S, Kang S, Kim CH, Lim YB. J Cell Biochem. 2013 Jun;114(6):1248-56. doi: 10.1002/jcb.24465. PubMed |
| Inhibition of connective tissue growth factor (CTGF/CCN2) in gallbladder cancer cells leads to decreased growth in vitro. Garcia P, Leal P, Ili C, Brebi P, Alvarez H, Roa JC. Int J Exp Pathol. 2013 Jun;94(3):195-202. doi: 10.1111/iep.12023. Epub 2013 Apr 18. PubMed |
| Cadherin-17 interacts with alpha2beta1 integrin to regulate cell proliferation and adhesion in colorectal cancer cells causing liver metastasis. Bartolome RA, Barderas R, Torres S, Fernandez-Acenero MJ, Mendes M, Garcia-Foncillas J, Lopez-Lucendo M, Casal JI. Oncogene. 2014 Mar 27;33(13):1658-69. doi: 10.1038/onc.2013.117. Epub 2013 Apr 22. PubMed |
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| MERTK controls melanoma cell migration and survival and differentially regulates cell behavior relative to AXL. Tworkoski KA, Platt JT, Bacchiocchi A, Bosenberg M, Boggon TJ, Stern DF. Pigment Cell Melanoma Res. 2013 Jul;26(4):527-41. doi: 10.1111/pcmr.12110. Epub 2013 May 21. PubMed |
| Propagation of human prostate cancer stem-like cells occurs through EGFR-mediated ERK activation. Rybak AP, Ingram AJ, Tang D. PLoS One. 2013 Apr 19;8(4):e61716. doi: 10.1371/journal.pone.0061716. Print 2013. PubMed |
| HOX antisense lincRNA HOXA-AS2 is an apoptosis repressor in all trans retinoic acid treated NB4 promyelocytic leukemia cells. Zhao H, Zhang X, Frazao JB, Condino-Neto A, Newburger PE. J Cell Biochem. 2013 Oct;114(10):2375-83. doi: 10.1002/jcb.24586. PubMed |
| RACK1 (receptor for activated C-kinase 1) interacts with FBW2 (F-box and WD-repeat domain-containing 2) to up-regulate GCM1 (glial cell missing 1) stability and placental cell migration and invasion. Wang CC, Lo HF, Lin SY, Chen H. Biochem J. 2013 Jul 15;453(2):201-8. doi: 10.1042/BJ20130175. PubMed |
| Dyskeratosis congenita mutations in dyskerin SUMOylation consensus sites lead to impaired telomerase RNA accumulation and telomere defects. Brault ME, Lauzon C, Autexier C. Hum Mol Genet. 2013 Sep 1;22(17):3498-507. doi: 10.1093/hmg/ddt204. Epub 2013 May 8. PubMed |
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| The B-cell-specific transcription factor and master regulator Pax5 promotes Epstein-Barr virus latency by negatively regulating the viral immediate early protein BZLF1. Raver RM, Panfil AR, Hagemeier SR, Kenney SC. J Virol. 2013 Jul;87(14):8053-63. doi: 10.1128/JVI.00546-13. Epub 2013 May 15. PubMed |
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| Focal adhesion kinase is required for IGF-I-mediated growth of skeletal muscle cells via a TSC2/mTOR/S6K1-associated pathway. Crossland H, Kazi AA, Lang CH, Timmons JA, Pierre P, Wilkinson DJ, Smith K, Szewczyk NJ, Atherton PJ. Am J Physiol Endocrinol Metab. 2013 Jul 15;305(2):E183-93. doi: 10.1152/ajpendo.00541.2012. Epub 2013 May 21. PubMed |
| Rapid assessment of RNAi-mediated protein depletion by selected reaction monitoring mass spectrometry. Glukhova VA, Tomazela DM, Findlay GD, Monnat RJ Jr, MacCoss MJ. J Proteome Res. 2013 Jul 5;12(7):3246-54. doi: 10.1021/pr400067k. Epub 2013 Jun 10. PubMed |
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| Dickkopf-related protein 3 promotes pathogenic stromal remodeling in benign prostatic hyperplasia and prostate cancer. Zenzmaier C, Sampson N, Plas E, Berger P. Prostate. 2013 Sep;73(13):1441-52. doi: 10.1002/pros.22691. Epub 2013 Jun 14. PubMed |
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| Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts. Lerner C, Bitto A, Pulliam D, Nacarelli T, Konigsberg M, Van Remmen H, Torres C, Sell C. Aging Cell. 2013 Dec;12(6):966-77. doi: 10.1111/acel.12122. Epub 2013 Jul 30. PubMed |
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| The RNA-binding protein fused in sarcoma (FUS) functions downstream of poly(ADP-ribose) polymerase (PARP) in response to DNA damage. Mastrocola AS, Kim SH, Trinh AT, Rodenkirch LA, Tibbetts RS. J Biol Chem. 2013 Aug 23;288(34):24731-41. doi: 10.1074/jbc.M113.497974. Epub 2013 Jul 5. PubMed |
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| LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program. Mao XG, Hutt-Cabezas M, Orr BA, Weingart M, Taylor I, Rajan AK, Odia Y, Kahlert U, Maciaczyk J, Nikkhah G, Eberhart CG, Raabe EH. Oncotarget. 2013 Jul;4(7):1050-64. PubMed |
| The telomere deprotection response is functionally distinct from the genomic DNA damage response. Cesare AJ, Hayashi MT, Crabbe L, Karlseder J. Mol Cell. 2013 Jul 25;51(2):141-55. doi: 10.1016/j.molcel.2013.06.006. Epub 2013 Jul 11. PubMed |
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| Rab18 binds to hepatitis C virus NS5A and promotes interaction between sites of viral replication and lipid droplets. Salloum S, Wang H, Ferguson C, Parton RG, Tai AW. PLoS Pathog. 2013;9(8):e1003513. doi: 10.1371/journal.ppat.1003513. Epub 2013 Aug 1. PubMed |
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| An isoform of C/EBPbeta, LIP, regulates expression of the chemokine receptor CXCR4 and modulates breast cancer cell migration. Park BH, Kook S, Lee S, Jeong JH, Brufsky A, Lee BC. J Biol Chem. 2013 Oct 4;288(40):28656-67. doi: 10.1074/jbc.M113.509505. Epub 2013 Aug 21. PubMed |
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| Acquired Resistance to the Hsp90 Inhibitor, Ganetespib, in KRAS-Mutant NSCLC Is Mediated via Reactivation of the ERK-p90RSK-mTOR Signaling Network. Chatterjee S, Huang EH, Christie I, Kurland BF, Burns TF. Mol Cancer Ther. 2017 May;16(5):793-804. doi: 10.1158/1535-7163.MCT-16-0677. Epub 2017 Feb 6. PubMed |
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| miR-302/367/LATS2/YAP pathway is essential for prostate tumor-propagating cells and promotes the development of castration resistance. Guo Y, Cui J, Ji Z, Cheng C, Zhang K, Zhang C, Chu M, Zhao Q, Yu Z, Zhang Y, Fang YX, Gao WQ, Zhu HH. Oncogene. 2017 Nov 9;36(45):6336-6347. doi: 10.1038/onc.2017.240. Epub 2017 Jul 24. PubMed |
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| Nestin expression is dynamically regulated in cardiomyocytes during embryogenesis. Hertig V, Matos-Nieves A, Garg V, Villeneuve L, Mamarbachi M, Caland L, Calderone A. J Cell Physiol. 2018 Apr;233(4):3218-3229. doi: 10.1002/jcp.26165. Epub 2017 Sep 27. PubMed |
| Lysosomotropism depends on glucose: a chloroquine resistance mechanism. Gallagher LE, Radhi OA, Abdullah MO, McCluskey AG, Boyd M, Chan EYW. Cell Death Dis. 2017 Aug 24;8(8):e3014. doi: 10.1038/cddis.2017.416. PubMed |
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| AKT inhibition is an effective treatment strategy in ARID1A-deficient gastric cancer cells. Lee D, Yu EJ, Ham IH, Hur H, Kim YS. Onco Targets Ther. 2017 Aug 22;10:4153-4159. doi: 10.2147/OTT.S139664. eCollection 2017. PubMed |
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| Enhancing CD8(+) T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy. Zhang Y, Kurupati R, Liu L, Zhou XY, Zhang G, Hudaihed A, Filisio F, Giles-Davis W, Xu X, Karakousis GC, Schuchter LM, Xu W, Amaravadi R, Xiao M, Sadek N, Krepler C, Herlyn M, Freeman GJ, Rabinowitz JD, Ertl HCJ. Cancer Cell. 2017 Sep 11;32(3):377-391.e9. doi: 10.1016/j.ccell.2017.08.004. PubMed |
| TMEM16A/ANO1 Inhibits Apoptosis Via Downregulation of Bim Expression. Godse NR, Khan N, Yochum ZA, Gomez-Casal R, Kemp C, Shiwarski DJ, Seethala RS, Kulich S, Seshadri M, Burns TF, Duvvuri U. Clin Cancer Res. 2017 Dec 1;23(23):7324-7332. doi: 10.1158/1078-0432.CCR-17-1561. Epub 2017 Sep 12. PubMed |
| KIF7 attenuates prostate tumor growth through LKB1-mediated AKT inhibition. Wong KY, Liu J, Chan KW. Oncotarget. 2017 Apr 26;8(33):54558-54571. doi: 10.18632/oncotarget.17421. eCollection 2017 Aug 15. PubMed |
| The N(6)-methyladenosine (m(6)A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells. Vu LP, Pickering BF, Cheng Y, Zaccara S, Nguyen D, Minuesa G, Chou T, Chow A, Saletore Y, MacKay M, Schulman J, Famulare C, Patel M, Klimek VM, Garrett-Bakelman FE, Melnick A, Carroll M, Mason CE, Jaffrey SR, Kharas MG. Nat Med. 2017 Nov;23(11):1369-1376. doi: 10.1038/nm.4416. Epub 2017 Sep 18. PubMed |
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| Mammalian target of rapamycin complex 1 activation sensitizes human glioma cells to hypoxia-induced cell death. Thiepold AL, Lorenz NI, Foltyn M, Engel AL, Dive I, Urban H, Heller S, Bruns I, Hofmann U, Drose S, Harter PN, Mittelbronn M, Steinbach JP, Ronellenfitsch MW. Brain. 2017 Oct 1;140(10):2623-2638. doi: 10.1093/brain/awx196. PubMed |
| Human Cytomegalovirus IE2 86 kDa Protein Induces STING Degradation and Inhibits cGAMP-Mediated IFN-beta Induction. Kim JE, Kim YE, Stinski MF, Ahn JH, Song YJ. Front Microbiol. 2017 Sep 26;8:1854. doi: 10.3389/fmicb.2017.01854. eCollection 2017. PubMed |
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Curved adhesions mediate cell attachment to soft matrix fibres in three dimensions.
Zhang W, Lu CH, Nakamoto ML, Tsai CT, Roy AR, Lee CE, Yang Y, Jahed Z, Li X, Cui B.
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