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- David Sabatini
- Sarbassov et al
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scramble shRNA Citations (567)
Originally described in: Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.Sarbassov DD, Guertin DA, Ali SM, Sabatini DM Science 2005 Feb 18;307(5712):1098-101. PubMed Journal
Articles Citing scramble shRNA
Showing 1 to 10 of 567 entries
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Notch signaling regulates UNC5B to suppress endothelial proliferation, migration, junction activity, and retinal plexus branching. Raza Q, Nadeem T, Youn SW, Swaminathan B, Gupta A, Sargis T, Du J, Cuervo H, Eichmann A, Ackerman SL, Naiche LA, Kitajewski J. Sci Rep. 2024 Jun 13;14(1):13603. doi: 10.1038/s41598-024-64375-z. PubMed |
Neratinib, a pan ERBB/HER inhibitor, restores sensitivity of PTEN-null, BRAFV600E melanoma to BRAF/MEK inhibition. DuBose E, Bevill SM, Mitchell DK, Sciaky N, Golitz BT, Dixon SAH, Rhodes SD, Bear JE, Johnson GL, Angus SP. Front Oncol. 2024 May 16;14:1191217. doi: 10.3389/fonc.2024.1191217. eCollection 2024. PubMed |
Selective and brain-penetrant ACSS2 inhibitors target breast cancer brain metastatic cells. Esquea EM, Ciraku L, Young RG, Merzy J, Talarico AN, Ahmed NN, Karuppiah M, Ramesh A, Chatoff A, Crispim CV, Rashad AA, Cocklin S, Snyder NW, Beld J, Simone NL, Reginato MJ, Dick A. Front Pharmacol. 2024 May 16;15:1394685. doi: 10.3389/fphar.2024.1394685. eCollection 2024. PubMed |
FOXA3 regulates cholesterol metabolism to compensate for low uptake during the progression of lung adenocarcinoma. Wang D, Cao Y, Meng M, Qiu J, Ni C, Guo X, Li Y, Liu S, Yu J, Guo M, Wang J, Du B, Qiu W, Xie C, Zhao B, Ma X, Cheng X, Xu L. PLoS Biol. 2024 May 28;22(5):e3002621. doi: 10.1371/journal.pbio.3002621. eCollection 2024 May. PubMed |
mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism. Levy T, Voeltzke K, Hruby L, Alasad K, Bas Z, Snaebjornsson M, Marciano R, Scharov K, Planque M, Vriens K, Christen S, Funk CM, Hassiepen C, Kahler A, Heider B, Picard D, Lim JKM, Stefanski A, Bendrin K, Vargas-Toscano A, Kahlert UD, Stuhler K, Remke M, Elkabets M, Grunewald TGP, Reichert AS, Fendt SM, Schulze A, Reifenberger G, Rotblat B, Leprivier G. Nat Commun. 2024 May 14;15(1):4083. doi: 10.1038/s41467-024-48386-y. PubMed |
CYB561 supports the neuroendocrine phenotype in castration-resistant prostate cancer. Azur RAG, Olarte KCV, Ybanez WS, Ocampo AMM, Bagamasbad PD. PLoS One. 2024 May 13;19(5):e0300413. doi: 10.1371/journal.pone.0300413. eCollection 2024. PubMed |
AKAP8 promotes ovarian cancer progression and antagonizes PARP inhibitor sensitivity through regulating hnRNPUL1 transcription. Mobet Y, Wang H, Wei Q, Liu X, Yang D, Zhao H, Yang Y, Ngono Ngane RA, Souopgui J, Xu J, Liu T, Yi P. iScience. 2024 Apr 16;27(5):109744. doi: 10.1016/j.isci.2024.109744. eCollection 2024 May 17. PubMed |
Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD). Zhang T, Ambrodji A, Huang H, Bouchonville KJ, Etheridge AS, Schmidt RE, Bembenek BM, Temesgen ZB, Wang Z, Innocenti F, Stroka D, Diasio RB, Largiader CR, Offer SM. Elife. 2024 Apr 30;13:RP94075. doi: 10.7554/eLife.94075. PubMed |
Regulation by the RNA-binding protein Unkempt at its effector interface. Shah K, He S, Turner DJ, Corbo J, Rebbani K, Dominguez D, Bateman JM, Cheloufi S, Igreja C, Valkov E, Murn J. Nat Commun. 2024 Apr 11;15(1):3159. doi: 10.1038/s41467-024-47449-4. PubMed |
IGSF3 is a homophilic cell adhesion molecule that drives lung metastasis of melanoma by promoting adhesion to vascular endothelium. Guo Y, Kasai Y, Tanaka Y, Ohashi-Kumagai Y, Sakamoto T, Ito T, Murakami Y. Cancer Sci. 2024 Jun;115(6):1936-1947. doi: 10.1111/cas.16166. Epub 2024 Apr 9. PubMed |
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