pCMV-PEmax-P2A-hMLH1dn Citations (9)
Originally described in: Enhanced prime editing systems by manipulating cellular determinants of editing outcomes.Chen PJ, Hussmann JA, Yan J, Knipping F, Ravisankar P, Chen PF, Chen C, Nelson JW, Newby GA, Sahin M, Osborn MJ, Weissman JS, Adamson B, Liu DR Cell. 2021 Oct 28;184(22):5635-5652.e29. doi: 10.1016/j.cell.2021.09.018. PubMed Journal
Articles Citing pCMV-PEmax-P2A-hMLH1dn
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Mutation-specific reporter for optimization and enrichment of prime editing.
Schene IF, Joore IP, Baijens JHL, Stevelink R, Kok G, Shehata S, Ilcken EF, Nieuwenhuis ECM, Bolhuis DP, van Rees RCM, Spelier SA, van der Doef HPJ, Beekman JM, Houwen RHJ, Nieuwenhuis EES, Fuchs SA.
Nat Commun. 2022 Mar 1;13(1):1028. doi: 10.1038/s41467-022-28656-3.
PubMed
Associated Plasmids |
A time-resolved, multi-symbol molecular recorder via sequential genome editing.
Choi J, Chen W, Minkina A, Chardon FM, Suiter CC, Regalado SG, Domcke S, Hamazaki N, Lee C, Martin B, Daza RM, Shendure J.
Nature. 2022 Jul 6. pii: 10.1038/s41586-022-04922-8. doi: 10.1038/s41586-022-04922-8.
PubMed
Associated Plasmids |
CRISPR prime editing for unconstrained correction of oncogenic KRAS variants.
Jang G, Kweon J, Kim Y.
Commun Biol. 2023 Jun 30;6(1):681. doi: 10.1038/s42003-023-05052-1.
PubMed
Associated Plasmids |
| A molecular proximity sensor based on an engineered, dual-component guide RNA. Choi J, Chen W, Liao H, Li X, Shendure J. bioRxiv [Preprint]. 2023 Aug 14:2023.08.14.553235. doi: 10.1101/2023.08.14.553235. PubMed |
| Development of a highly efficient prime editor system in mice and rabbits. Qian Y, Wang D, Niu W, Shi Z, Wu M, Zhao D, Li J, Gao X, Zhang Z, Lai L, Li Z. Cell Mol Life Sci. 2023 Nov 4;80(11):346. doi: 10.1007/s00018-023-05003-3. PubMed |
Improving prime editing with an endogenous small RNA-binding protein.
Yan J, Oyler-Castrillo P, Ravisankar P, Ward CC, Levesque S, Jing Y, Simpson D, Zhao A, Li H, Yan W, Goudy L, Schmidt R, Solley SC, Gilbert LA, Chan MM, Bauer DE, Marson A, Parsons LR, Adamson B.
Nature. 2024 Apr 3. doi: 10.1038/s41586-024-07259-6.
PubMed
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| Chromatin context-dependent regulation and epigenetic manipulation of prime editing. Li X, Chen W, Martin BK, Calderon D, Lee C, Choi J, Chardon FM, McDiarmid TA, Daza RM, Kim H, Lalanne JB, Nathans JF, Lee DS, Shendure J. Cell. 2024 May 9;187(10):2411-2427.e25. doi: 10.1016/j.cell.2024.03.020. Epub 2024 Apr 11. PubMed |
| Massively parallel screen uncovers many rare 3' UTR variants regulating mRNA abundance of cancer driver genes. Fu T, Amoah K, Chan TW, Bahn JH, Lee JH, Terrazas S, Chong R, Kosuri S, Xiao X. Nat Commun. 2024 Apr 18;15(1):3335. doi: 10.1038/s41467-024-46795-7. PubMed |
Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells.
Bulcaen M, Kortleven P, Liu RB, Maule G, Dreano E, Kelly M, Ensinck MM, Thierie S, Smits M, Ciciani M, Hatton A, Chevalier B, Ramalho AS, Casadevall I Solvas X, Debyser Z, Vermeulen F, Gijsbers R, Sermet-Gaudelus I, Cereseto A, Carlon MS.
Cell Rep Med. 2024 May 21;5(5):101544. doi: 10.1016/j.xcrm.2024.101544. Epub 2024 May 1.
PubMed
Associated Plasmids |
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