Skip to main content
Addgene

pLenti CMV GFP Puro (658-5) Citations (153)

Originally described in: A versatile viral system for expression and depletion of proteins in mammalian cells.
Campeau E, Ruhl VE, Rodier F, Smith CL, Rahmberg BL, Fuss JO, Campisi J, Yaswen P, Cooper PK, Kaufman PD. PLoS One. 2009 Aug 6;4(8):e6529. PubMed Journal

Articles Citing pLenti CMV GFP Puro (658-5)

Articles
Internal polyadenylation of parvoviral precursor mRNA limits progeny virus production. Huang Q, Deng X, Best SM, Bloom ME, Li Y, Qiu J. Virology. 2012 May 10;426(2):167-77. doi: 10.1016/j.virol.2012.01.031. Epub 2012 Feb 21. PubMed
The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis. Lu X, Mazur SJ, Lin T, Appella E, Xu Y. Oncogene. 2014 May 15;33(20):2655-64. doi: 10.1038/onc.2013.209. Epub 2013 Jun 17. PubMed
Impairment of endothelial-myocardial interaction increases the susceptibility of cardiomyocytes to ischemia/reperfusion injury. Leucker TM, Ge ZD, Procknow J, Liu Y, Shi Y, Bienengraeber M, Warltier DC, Kersten JR. PLoS One. 2013 Jul 22;8(7):e70088. doi: 10.1371/journal.pone.0070088. Print 2013. PubMed
PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1. Gont A, Hanson JE, Lavictoire SJ, Parolin DA, Daneshmand M, Restall IJ, Soucie M, Nicholas G, Woulfe J, Kassam A, Da Silva VF, Lorimer IA. Oncotarget. 2013 Aug;4(8):1266-79. PubMed
CRR9/CLPTM1L regulates cell survival signaling and is required for Ras transformation and lung tumorigenesis. James MA, Vikis HG, Tate E, Rymaszewski AL, You M. Cancer Res. 2014 Feb 15;74(4):1116-27. doi: 10.1158/0008-5472.CAN-13-1617. Epub 2013 Dec 23. PubMed
Injection parameters and virus dependent choice of promoters to improve neuron targeting in the nonhuman primate brain. Lerchner W, Corgiat B, Der Minassian V, Saunders RC, Richmond BJ. Gene Ther. 2014 Mar;21(3):233-41. doi: 10.1038/gt.2013.75. Epub 2014 Jan 9. PubMed
Astrocyte-like cells derived from human oral mucosa stem cells provide neuroprotection in vitro and in vivo. Ganz J, Arie I, Ben-Zur T, Dadon-Nachum M, Pour S, Araidy S, Pitaru S, Offen D. Stem Cells Transl Med. 2014 Mar;3(3):375-86. doi: 10.5966/sctm.2013-0074. Epub 2014 Jan 29. PubMed
Crosstalk between nuclear MET and SOX9/beta-catenin correlates with castration-resistant prostate cancer. Xie Y, Lu W, Liu S, Yang Q, Carver BS, Li E, Wang Y, Fazli L, Gleave M, Chen Z. Mol Endocrinol. 2014 Oct;28(10):1629-39. doi: 10.1210/me.2014-1078. Epub 2014 Aug 6. PubMed
Toward operative in vivo fluorescence imaging of the c-Met proto-oncogene for personalization of therapy in ovarian cancer. Liu S, Zheng Y, Volpi D, El-Kasti M, Klotz D, Tullis I, Henricks A, Campo L, Myers K, Laios A, Thomas P, Ng T, Dhar S, Becker C, Vojnovic B, Ahmed AA. Cancer. 2015 Jan 15;121(2):202-13. doi: 10.1002/cncr.29029. Epub 2014 Sep 10. PubMed
Simultaneous mapping of membrane voltage and calcium in zebrafish heart in vivo reveals chamber-specific developmental transitions in ionic currents. Hou JH, Kralj JM, Douglass AD, Engert F, Cohen AE. Front Physiol. 2014 Sep 11;5:344. doi: 10.3389/fphys.2014.00344. eCollection 2014. PubMed
Extracellular metabolic energetics can promote cancer progression. Loo JM, Scherl A, Nguyen A, Man FY, Weinberg E, Zeng Z, Saltz L, Paty PB, Tavazoie SF. Cell. 2015 Jan 29;160(3):393-406. doi: 10.1016/j.cell.2014.12.018. Epub 2015 Jan 15. PubMed
Sustained regeneration of high-volume adipose tissue for breast reconstruction using computer aided design and biomanufacturing. Chhaya MP, Melchels FP, Holzapfel BM, Baldwin JG, Hutmacher DW. Biomaterials. 2015 Jun;52:551-60. doi: 10.1016/j.biomaterials.2015.01.025. Epub 2015 Mar 18. PubMed
Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells. Liao J, Karnik R, Gu H, Ziller MJ, Clement K, Tsankov AM, Akopian V, Gifford CA, Donaghey J, Galonska C, Pop R, Reyon D, Tsai SQ, Mallard W, Joung JK, Rinn JL, Gnirke A, Meissner A. Nat Genet. 2015 May;47(5):469-78. doi: 10.1038/ng.3258. Epub 2015 Mar 30. PubMed
E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3. Chesarino NM, McMichael TM, Yount JS. PLoS Pathog. 2015 Aug 11;11(8):e1005095. doi: 10.1371/journal.ppat.1005095. eCollection 2015 Aug. PubMed

Associated Plasmids
Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts. Scarfo I, Pellegrino E, Mereu E, Kwee I, Agnelli L, Bergaggio E, Garaffo G, Vitale N, Caputo M, Machiorlatti R, Circosta P, Abate F, Barreca A, Novero D, Mathew S, Rinaldi A, Tiacci E, Serra S, Deaglio S, Neri A, Falini B, Rabadan R, Bertoni F, Inghirami G, Piva R. Blood. 2016 Jan 14;127(2):221-32. doi: 10.1182/blood-2014-12-614503. Epub 2015 Oct 13. PubMed
Translocator Protein (TSPO) Affects Mitochondrial Fatty Acid Oxidation in Steroidogenic Cells. Tu LN, Zhao AH, Hussein M, Stocco DM, Selvaraj V. Endocrinology. 2016 Mar;157(3):1110-21. doi: 10.1210/en.2015-1795. Epub 2016 Jan 7. PubMed
Lineage Reprogramming of Fibroblasts into Proliferative Induced Cardiac Progenitor Cells by Defined Factors. Lalit PA, Salick MR, Nelson DO, Squirrell JM, Shafer CM, Patel NG, Saeed I, Schmuck EG, Markandeya YS, Wong R, Lea MR, Eliceiri KW, Hacker TA, Crone WC, Kyba M, Garry DJ, Stewart R, Thomson JA, Downs KM, Lyons GE, Kamp TJ. Cell Stem Cell. 2016 Mar 3;18(3):354-67. doi: 10.1016/j.stem.2015.12.001. Epub 2016 Feb 11. PubMed

Associated Plasmids
SOX5 is involved in balanced MITF regulation in human melanoma cells. Kordass T, Weber CE, Oswald M, Ast V, Bernhardt M, Novak D, Utikal J, Eichmuller SB, Konig R. BMC Med Genomics. 2016 Feb 29;9:10. doi: 10.1186/s12920-016-0170-0. PubMed
Analysis of Nuclear Lamina Proteins in Myoblast Differentiation by Functional Complementation. Tapia O, Gerace L. Methods Mol Biol. 2016;1411:177-94. doi: 10.1007/978-1-4939-3530-7_11. PubMed
Discoidin Receptor 2 Controls Bone Formation and Marrow Adipogenesis. Ge C, Wang Z, Zhao G, Li B, Liao J, Sun H, Franceschi RT. J Bone Miner Res. 2016 Jun 24. doi: 10.1002/jbmr.2893. PubMed
Activation of the Met kinase confers acquired drug resistance in FGFR-targeted lung cancer therapy. Kim SM, Kim H, Yun MR, Kang HN, Pyo KH, Park HJ, Lee JM, Choi HM, Ellinghaus P, Ocker M, Paik S, Kim HR, Cho BC. Oncogenesis. 2016 Jul 18;5(7):e241. doi: 10.1038/oncsis.2016.48. PubMed
Physiological and hypoxic oxygen concentration differentially regulates human c-Kit+ cardiac stem cell proliferation and migration. Bellio MA, Rodrigues CO, Landin AM, Hatzistergos KE, Kuznetsov J, Florea V, Valasaki K, Khan A, Hare JM, Schulman IH. Am J Physiol Heart Circ Physiol. 2016 Dec 1;311(6):H1509-H1519. doi: 10.1152/ajpheart.00449.2016. Epub 2016 Sep 30. PubMed
The mechanism of CIRP in inhibition of keratinocytes growth arrest and apoptosis following low dose UVB radiation. Liao Y, Feng J, Zhang Y, Tang L, Wu S. Mol Carcinog. 2016 Nov 19. doi: 10.1002/mc.22597. PubMed
A computationally engineered RAS rheostat reveals RAS-ERK signaling dynamics. Rose JC, Huang PS, Camp ND, Ye J, Leidal AM, Goreshnik I, Trevillian BM, Dickinson MS, Cunningham-Bryant D, Debnath J, Baker D, Wolf-Yadlin A, Maly DJ. Nat Chem Biol. 2016 Nov 21. doi: 10.1038/nchembio.2244. PubMed

Associated Plasmids
EV71 3D Protein Binds with NLRP3 and Enhances the Assembly of Inflammasome Complex. Wang W, Xiao F, Wan P, Pan P, Zhang Y, Liu F, Wu K, Liu Y, Wu J. PLoS Pathog. 2017 Jan 6;13(1):e1006123. doi: 10.1371/journal.ppat.1006123. PubMed
Motility of glioblastoma cells is driven by netrin-1 induced gain of stemness. Ylivinkka I, Sihto H, Tynninen O, Hu Y, Laakso A, Kivisaari R, Laakkonen P, Keski-Oja J, Hyytiainen M. J Exp Clin Cancer Res. 2017 Jan 9;36(1):9. doi: 10.1186/s13046-016-0482-0. PubMed
Diet-induced obesity links to ER positive breast cancer progression via LPA/PKD-1-CD36 signaling-mediated microvascular remodeling. Dong L, Yuan Y, Opansky C, Chen Y, Aguilera-Barrantes I, Wu S, Yuan R, Cao Q, Cheng YC, Sahoo D, Silverstein RL, Ren B. Oncotarget. 2017 Apr 4;8(14):22550-22562. doi: 10.18632/oncotarget.15123. PubMed
Geometry-dependent functional changes in iPSC-derived cardiomyocytes probed by functional imaging and RNA sequencing. Werley CA, Chien MP, Gaublomme J, Shekhar K, Butty V, Yi BA, Kralj JM, Bloxham W, Boyer LA, Regev A, Cohen AE. PLoS One. 2017 Mar 23;12(3):e0172671. doi: 10.1371/journal.pone.0172671. eCollection 2017. PubMed
Dissection of ubiquitinated protein degradation by basal autophagy. Takayama K, Matsuura A, Itakura E. FEBS Lett. 2017 May;591(9):1199-1211. doi: 10.1002/1873-3468.12641. Epub 2017 Apr 18. PubMed
Generation of multipotent induced cardiac progenitor cells from mouse fibroblasts and potency testing in ex vivo mouse embryos. Lalit PA, Rodriguez AM, Downs KM, Kamp TJ. Nat Protoc. 2017 May;12(5):1029-1054. doi: 10.1038/nprot.2017.021. Epub 2017 Apr 20. PubMed
A Survey of DDX21 Activity During Rev/RRE Complex Formation. Hammond JA, Zhou L, Lamichhane R, Chu HY, Millar DP, Gerace L, Williamson JR. J Mol Biol. 2018 Feb 16;430(4):537-553. doi: 10.1016/j.jmb.2017.06.023. Epub 2017 Jul 10. PubMed

Associated Plasmids
Strategies to Develop Therapeutic N- and O-Hyperglycosylated Proteins. Gugliotta A, Ceaglio N, Etcheverrigaray M, Kratje R, Oggero M. Methods Mol Biol. 2018;1674:163-181. doi: 10.1007/978-1-4939-7312-5_13. PubMed
Single-cell transcriptomics reconstructs fate conversion from fibroblast to cardiomyocyte. Liu Z, Wang L, Welch JD, Ma H, Zhou Y, Vaseghi HR, Yu S, Wall JB, Alimohamadi S, Zheng M, Yin C, Shen W, Prins JF, Liu J, Qian L. Nature. 2017 Nov 2;551(7678):100-104. doi: 10.1038/nature24454. Epub 2017 Oct 25. PubMed
Both cytopathic and non-cytopathic bovine viral diarrhea virus (BVDV) induced autophagy at a similar rate. Rajput MKS, Abdelsalam K, Darweesh MF, Braun LJ, Kerkvliet J, Hoppe AD, Chase CCL. Vet Immunol Immunopathol. 2017 Dec;193-194:1-9. doi: 10.1016/j.vetimm.2017.09.006. Epub 2017 Oct 2. PubMed
Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Melanoma Survival Gene. Fontanals-Cirera B, Hasson D, Vardabasso C, Di Micco R, Agrawal P, Chowdhury A, Gantz M, de Pablos-Aragoneses A, Morgenstern A, Wu P, Filipescu D, Valle-Garcia D, Darvishian F, Roe JS, Davies MA, Vakoc CR, Hernando E, Bernstein E. Mol Cell. 2017 Nov 16;68(4):731-744.e9. doi: 10.1016/j.molcel.2017.11.004. PubMed
Bacteria induce autophagy in a human ocular surface cell line. Brothers KM, Kowalski RP, Tian S, Kinchington PR, Shanks RMQ. Exp Eye Res. 2018 Mar;168:12-18. doi: 10.1016/j.exer.2017.12.010. Epub 2017 Dec 27. PubMed
Force Generation via beta-Cardiac Myosin, Titin, and alpha-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions. Chopra A, Kutys ML, Zhang K, Polacheck WJ, Sheng CC, Luu RJ, Eyckmans J, Hinson JT, Seidman JG, Seidman CE, Chen CS. Dev Cell. 2018 Jan 8;44(1):87-96.e5. doi: 10.1016/j.devcel.2017.12.012. Epub 2018 Jan 8. PubMed
A type III complement factor D deficiency: Structural insights for inhibition of the alternative pathway. Sng CCT, O'Byrne S, Prigozhin DM, Bauer MR, Harvey JC, Ruhle M, Challis BG, Lear S, Roberts LD, Workman S, Janowitz T, Magiera L, Doffinger R, Buckland MS, Jodrell DJ, Semple RK, Wilson TJ, Modis Y, Thaventhiran JED. J Allergy Clin Immunol. 2018 Jul;142(1):311-314.e6. doi: 10.1016/j.jaci.2018.01.048. Epub 2018 Mar 6. PubMed
The Forkhead Transcription Factor FOXC2 Is Required for Maintaining Murine Spermatogonial Stem Cells. Wei C, Lin H, Cui S. Stem Cells Dev. 2018 May 1;27(9):624-636. doi: 10.1089/scd.2017.0233. Epub 2018 Apr 26. PubMed
miRNA 146a promotes chemotherapy resistance in lung cancer cells by targeting DNA damage inducible transcript 3 (CHOP). Tan W, Liao Y, Qiu Y, Liu H, Tan D, Wu T, Tang M, Zhang S, Wang H. Cancer Lett. 2018 Aug 1;428:55-68. doi: 10.1016/j.canlet.2018.04.028. Epub 2018 Apr 24. PubMed
Identification of Genomic and Molecular Traits that Present Therapeutic Vulnerability to HGF-targeted therapy in Glioblastoma. Sa JK, Kim SH, Lee JK, Cho HJ, Shin YJ, Shin H, Koo H, Kim D, Lee M, Kang W, Hong SH, Kim JY, Park YW, Song SW, Lee SJ, Joo KM, Nam DH. Neuro Oncol. 2018 Jun 23. pii: 5043207. doi: 10.1093/neuonc/noy105. PubMed
Targeted Enhancer Activation by a Subunit of the Integrator Complex. Barbieri E, Trizzino M, Welsh SA, Owens TA, Calabretta B, Carroll M, Sarma K, Gardini A. Mol Cell. 2018 Jul 5;71(1):103-116.e7. doi: 10.1016/j.molcel.2018.05.031. Epub 2018 Jun 28. PubMed
Direct Reprogramming of Fibroblasts Into Smooth Muscle-Like Cells With Defined Transcription Factors-Brief Report. Hirai H, Yang B, Garcia-Barrio MT, Rom O, Ma PX, Zhang J, Chen YE. Arterioscler Thromb Vasc Biol. 2018 Sep;38(9):2191-2197. doi: 10.1161/ATVBAHA.118.310870. PubMed
Identification of SMCHD1 domains for nuclear localization, homo-dimerization, and protein cleavage. Hiramuki Y, Tapscott SJ. Skelet Muscle. 2018 Aug 2;8(1):24. doi: 10.1186/s13395-018-0172-z. PubMed

Associated Plasmids
The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes. Chen J, Cai Z, Bai M, Yu X, Zhang C, Cao C, Hu X, Wang L, Su R, Wang D, Wang L, Yao Y, Ye R, Hou B, Yu Y, Yu S, Li J, Xue Y. Cell Res. 2018 Oct;28(10):981-995. doi: 10.1038/s41422-018-0076-9. Epub 2018 Aug 24. PubMed
Treatment of a metabolic liver disease by in vivo genome base editing in adult mice. Villiger L, Grisch-Chan HM, Lindsay H, Ringnalda F, Pogliano CB, Allegri G, Fingerhut R, Haberle J, Matos J, Robinson MD, Thony B, Schwank G. Nat Med. 2018 Oct;24(10):1519-1525. doi: 10.1038/s41591-018-0209-1. Epub 2018 Oct 8. PubMed

Associated Plasmids
Regulation of Neuroregeneration by Long Noncoding RNAs. Perry RB, Hezroni H, Goldrich MJ, Ulitsky I. Mol Cell. 2018 Nov 1;72(3):553-567.e5. doi: 10.1016/j.molcel.2018.09.021. Epub 2018 Oct 25. PubMed

Associated Plasmids
Integrated Phosphoproteome and Transcriptome Analysis Reveals Chlamydia-Induced Epithelial-to-Mesenchymal Transition in Host Cells. Zadora PK, Chumduri C, Imami K, Berger H, Mi Y, Selbach M, Meyer TF, Gurumurthy RK. Cell Rep. 2019 Jan 29;26(5):1286-1302.e8. doi: 10.1016/j.celrep.2019.01.006. PubMed
Patterning of human epidermal stem cells on undulating elastomer substrates reflects differences in cell stiffness. Mobasseri SA, Zijl S, Salameti V, Walko G, Stannard A, Garcia-Manyes S, Watt FM. Acta Biomater. 2019 Mar 15;87:256-264. doi: 10.1016/j.actbio.2019.01.063. Epub 2019 Jan 30. PubMed
Wild-Type p53 Promotes Cancer Metabolic Switch by Inducing PUMA-Dependent Suppression of Oxidative Phosphorylation. Kim J, Yu L, Chen W, Xu Y, Wu M, Todorova D, Tang Q, Feng B, Jiang L, He J, Chen G, Fu X, Xu Y. Cancer Cell. 2019 Feb 11;35(2):191-203.e8. doi: 10.1016/j.ccell.2018.12.012. Epub 2019 Jan 31. PubMed
TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma. Zhang J, Liu P, Tao J, Wang P, Zhang Y, Song X, Che L, Sumazin P, Ribback S, Kiss A, Schaff Z, Cigliano A, Dombrowski F, Cossu C, Pascale RM, Calvisi DF, Monga SP, Chen X. Am J Pathol. 2019 May;189(5):1077-1090. doi: 10.1016/j.ajpath.2019.01.016. Epub 2019 Feb 19. PubMed
Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA. Barnett KC, Coronas-Serna JM, Zhou W, Ernandes MJ, Cao A, Kranzusch PJ, Kagan JC. Cell. 2019 Mar 7;176(6):1432-1446.e11. doi: 10.1016/j.cell.2019.01.049. Epub 2019 Feb 28. PubMed

Associated Plasmids
Actomyosin contractility-dependent matrix stretch and recoil induces rapid cell migration. Wang WY, Davidson CD, Lin D, Baker BM. Nat Commun. 2019 Mar 12;10(1):1186. doi: 10.1038/s41467-019-09121-0. PubMed
TFEB-driven lysosomal biogenesis is pivotal for PGC1alpha-dependent renal stress resistance. Lynch MR, Tran MT, Ralto KM, Zsengeller ZK, Raman V, Bhasin SS, Sun N, Chen X, Brown D, Rovira II, Taguchi K, Brooks CR, Stillman IE, Bhasin MK, Finkel T, Parikh SM. JCI Insight. 2019 Mar 14;5. pii: 126749. doi: 10.1172/jci.insight.126749. PubMed
Promyelocytic leukemia protein (PML) controls breast cancer cell proliferation by modulating Forkhead transcription factors. Sachini N, Arampatzi P, Klonizakis A, Nikolaou C, Makatounakis T, Lam EW, Kretsovali A, Papamatheakis J. Mol Oncol. 2019 Jun;13(6):1369-1387. doi: 10.1002/1878-0261.12486. Epub 2019 May 16. PubMed
Analysis of herpes simplex type 1 gB, gD, and gH/gL on production of infectious HIV-1: HSV-1 gD restricts HIV-1 by exclusion of HIV-1 Env from maturing viral particles. Polpitiya Arachchige S, Henke W, Kalamvoki M, Stephens EB. Retrovirology. 2019 Apr 2;16(1):9. doi: 10.1186/s12977-019-0470-5. PubMed
Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish. Yan C, Brunson DC, Tang Q, Do D, Iftimia NA, Moore JC, Hayes MN, Welker AM, Garcia EG, Dubash TD, Hong X, Drapkin BJ, Myers DT, Phat S, Volorio A, Marvin DL, Ligorio M, Dershowitz L, McCarthy KM, Karabacak MN, Fletcher JA, Sgroi DC, Iafrate JA, Maheswaran S, Dyson NJ, Haber DA, Rawls JF, Langenau DM. Cell. 2019 Jun 13;177(7):1903-1914.e14. doi: 10.1016/j.cell.2019.04.004. Epub 2019 Apr 25. PubMed
Activity-Structure Study on the Peptide Fraction of AG2: a Potent In Vitro Transfection Agent. Grippo LD, Rudi JM, De Zan MM, Giorello A, Antuna S, Prieto CC, Veaute CMI, Muller DM. Appl Biochem Biotechnol. 2019 May 16. pii: 10.1007/s12010-019-02999-y. doi: 10.1007/s12010-019-02999-y. PubMed
Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer. Kang YP, Torrente L, Falzone A, Elkins CM, Liu M, Asara JM, Dibble CC, DeNicola GM. Elife. 2019 May 20;8. pii: 45572. doi: 10.7554/eLife.45572. PubMed
Conversion Tract Analysis of Homology-Directed Genome Editing Using Oligonucleotide Donors. Kan Y, Hendrickson EA. Methods Mol Biol. 2019;1999:131-144. doi: 10.1007/978-1-4939-9500-4_7. PubMed
Induced pluripotent stem cell generation from bovine somatic cells indicates unmet needs for pluripotency sustenance. Pillai VV, Kei TG, Reddy SE, Das M, Abratte C, Cheong SH, Selvaraj V. Anim Sci J. 2019 Sep;90(9):1149-1160. doi: 10.1111/asj.13272. Epub 2019 Jul 19. PubMed
Structural and functional insights into the bona fide catalytic state of Streptococcus pyogenes Cas9 HNH nuclease domain. Zuo Z, Zolekar A, Babu K, Lin VJ, Hayatshahi HS, Rajan R, Wang YC, Liu J. Elife. 2019 Jul 30;8. pii: 46500. doi: 10.7554/eLife.46500. PubMed
The RING-type E3 ligase RNF186 ubiquitinates Sestrin-2 and thereby controls nutrient sensing. Lear TB, Lockwood KC, Ouyang Y, Evankovich JW, Larsen MB, Lin B, Liu Y, Chen BB. J Biol Chem. 2019 Nov 8;294(45):16527-16534. doi: 10.1074/jbc.AC119.010671. Epub 2019 Oct 4. PubMed
Establishing Renal Proximal Tubule Epithelial-Derived Cell Lines Expressing Human Telomerase Reverse Transcriptase for Studying BK Polyomavirus. Zhao L, Imperiale MJ. Microbiol Resour Announc. 2019 Oct 17;8(42). pii: 8/42/e01129-19. doi: 10.1128/MRA.01129-19. PubMed
Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion. Meant A, Gao B, Lavoie G, Nourreddine S, Jung F, Aubert L, Tcherkezian J, Gingras AC, Roux PP. Mol Cell Proteomics. 2020 Jan;19(1):50-64. doi: 10.1074/mcp.RA119.001811. Epub 2019 Nov 2. PubMed
A Versatile ES Cell-Based Melanoma Mouse Modeling Platform. Bok I, Vera O, Xu X, Jasani N, Nakamura K, Reff J, Nenci A, Gonzalez JG, Karreth FA. Cancer Res. 2020 Feb 15;80(4):912-921. doi: 10.1158/0008-5472.CAN-19-2924. Epub 2019 Nov 19. PubMed
Enterovirus 71 Represses Interleukin Enhancer-Binding Factor 2 Production and Nucleus Translocation to Antagonize ILF2 Antiviral Effects. Jin J, Wang W, Ai S, Liu W, Song Y, Luo Z, Zhang Q, Wu K, Liu Y, Wu J. Viruses. 2019 Dec 23;12(1). pii: v12010022. doi: 10.3390/v12010022. PubMed
A fluorescence activatable reporter of flavivirus NS2B-NS3 protease activity enables live imaging of infection in single cells and viral plaques. Arias-Arias JL, MacPherson DJ, Hill ME, Hardy JA, Mora-Rodriguez R. J Biol Chem. 2020 Jan 9. pii: RA119.011319. doi: 10.1074/jbc.RA119.011319. PubMed

Associated Plasmids
MTR4 drives liver tumorigenesis by promoting cancer metabolic switch through alternative splicing. Yu L, Kim J, Jiang L, Feng B, Ying Y, Ji KY, Tang Q, Chen W, Mai T, Dou W, Zhou J, Xiang LY, He YF, Yang D, Li Q, Fu X, Xu Y. Nat Commun. 2020 Feb 5;11(1):708. doi: 10.1038/s41467-020-14437-3. PubMed
Functional angiogenesis requires microenvironmental cues balancing endothelial cell migration and proliferation. Wang WY, Lin D, Jarman EH, Polacheck WJ, Baker BM. Lab Chip. 2020 Mar 17;20(6):1153-1166. doi: 10.1039/c9lc01170f. PubMed
CAS9 is a genome mutator by directly disrupting DNA-PK dependent DNA repair pathway. Xu S, Kim J, Tang Q, Chen Q, Liu J, Xu Y, Fu X. Protein Cell. 2020 May;11(5):352-365. doi: 10.1007/s13238-020-00699-6. Epub 2020 Mar 13. PubMed
The Role of Membrane Capacitance in Cardiac Impulse Conduction: An Optogenetic Study With Non-excitable Cells Coupled to Cardiomyocytes. De Simone SA, Moyle S, Buccarello A, Dellenbach C, Kucera JP, Rohr S. Front Physiol. 2020 Mar 26;11:194. doi: 10.3389/fphys.2020.00194. eCollection 2020. PubMed
Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation. You L, Chen J, Liu W, Xiang Q, Luo Z, Wang W, Xu W, Wu K, Zhang Q, Liu Y, Wu J. Virulence. 2020 Dec;11(1):537-553. doi: 10.1080/21505594.2020.1766790. PubMed
Efficient CRISPR/Cas9 genome editing in a salmonid fish cell line using a lentivirus delivery system. Gratacap RL, Regan T, Dehler CE, Martin SAM, Boudinot P, Collet B, Houston RD. BMC Biotechnol. 2020 Jun 23;20(1):35. doi: 10.1186/s12896-020-00626-x. PubMed
EXO1 Plays a Carcinogenic Role in Hepatocellular Carcinoma and is related to the regulation of FOXP3. Yang G, Dong K, Zhang Z, Zhang E, Liang B, Chen X, Huang Z. J Cancer. 2020 Jun 16;11(16):4917-4932. doi: 10.7150/jca.40673. eCollection 2020. PubMed
Mithramycin A and Mithralog EC-8042 Inhibit SETDB1 Expression and Its Oncogenic Activity in Malignant Melanoma. Federico A, Steinfass T, Larribere L, Novak D, Moris F, Nunez LE, Umansky V, Utikal J. Mol Ther Oncolytics. 2020 Jun 4;18:83-99. doi: 10.1016/j.omto.2020.06.001. eCollection 2020 Sep 25. PubMed
An Optimized Protocol for Human Direct Cardiac Reprogramming. Garbutt TA, Zhou Y, Keepers B, Liu J, Qian L. STAR Protoc. 2020 Jun 19;1(1). doi: 10.1016/j.xpro.2019.100010. Epub 2020 Jun 3. PubMed
Down-regulation of Beclin1 promotes direct cardiac reprogramming. Wang L, Ma H, Huang P, Xie Y, Near D, Wang H, Xu J, Yang Y, Xu Y, Garbutt T, Zhou Y, Liu Z, Yin C, Bressan M, Taylor JM, Liu J, Qian L. Sci Transl Med. 2020 Oct 21;12(566). pii: 12/566/eaay7856. doi: 10.1126/scitranslmed.aay7856. PubMed
An ACE2 Microbody Containing a Single Immunoglobulin Fc Domain Is a Potent Inhibitor of SARS-CoV-2. Tada T, Fan C, Chen JS, Kaur R, Stapleford KA, Gristick H, Dcosta BM, Wilen CB, Nimigean CM, Landau NR. Cell Rep. 2020 Dec 22;33(12):108528. doi: 10.1016/j.celrep.2020.108528. Epub 2020 Dec 1. PubMed
Hepatic Stellate Cells in Hepatocellular Carcinoma Promote Tumor Growth Via Growth Differentiation Factor 15 Production. Myojin Y, Hikita H, Sugiyama M, Sasaki Y, Fukumoto K, Sakane S, Makino Y, Takemura N, Yamada R, Shigekawa M, Kodama T, Sakamori R, Kobayashi S, Tatsumi T, Suemizu H, Eguchi H, Kokudo N, Mizokami M, Takehara T. Gastroenterology. 2021 Apr;160(5):1741-1754.e16. doi: 10.1053/j.gastro.2020.12.015. Epub 2020 Dec 17. PubMed
Aberrant Induction of a Mesenchymal/Stem Cell Program Engages Senescence in Normal Mammary Epithelial Cells. Bryson BL, Tamagno I, Taylor SE, Parameswaran N, Chernosky NM, Balasubramaniam N, Jackson MW. Mol Cancer Res. 2021 Apr;19(4):651-666. doi: 10.1158/1541-7786.MCR-19-1181. Epub 2020 Dec 22. PubMed
ER-directed TREX1 limits cGAS activation at micronuclei. Mohr L, Toufektchan E, von Morgen P, Chu K, Kapoor A, Maciejowski J. Mol Cell. 2021 Jan 12. pii: S1097-2765(20)30958-8. doi: 10.1016/j.molcel.2020.12.037. PubMed

Associated Plasmids
Neutralization of viruses with European, South African, and United States SARS-CoV-2 variant spike proteins by convalescent sera and BNT162b2 mRNA vaccine-elicited antibodies. Tada T, Dcosta BM, Samanovic-Golden M, Herati RS, Cornelius A, Mulligan MJ, Landau NR. bioRxiv. 2021 Feb 7. doi: 10.1101/2021.02.05.430003. PubMed
Evidence for the loss and recovery of SLAMF9 during human evolution: implications on Dollo's law. Murphy MK, Moon JT, Skolaris AT, Mikulin JA, Wilson TJ. Immunogenetics. 2021 Jun;73(3):243-251. doi: 10.1007/s00251-021-01208-7. Epub 2021 Feb 22. PubMed
miR-582-5p Is a Tumor Suppressor microRNA Targeting the Hippo-YAP/TAZ Signaling Pathway in Non-Small Cell Lung Cancer. Zhu B, V M, Finch-Edmondson M, Lee Y, Wan Y, Sudol M, DasGupta R. Cancers (Basel). 2021 Feb 11;13(4). pii: cancers13040756. doi: 10.3390/cancers13040756. PubMed
SARS-CoV-2 ORF6 Disrupts Bidirectional Nucleocytoplasmic Transport through Interactions with Rae1 and Nup98. Addetia A, Lieberman NAP, Phung Q, Hsiang TY, Xie H, Roychoudhury P, Shrestha L, Loprieno MA, Huang ML, Gale M Jr, Jerome KR, Greninger AL. mBio. 2021 Apr 13;12(2). pii: mBio.00065-21. doi: 10.1128/mBio.00065-21. PubMed
Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment. Pettinato AM, Yoo D, VanOudenhove J, Chen YS, Cohn R, Ladha FA, Yang X, Thakar K, Romano R, Legere N, Meredith E, Robson P, Regnier M, Cotney JL, Murry CE, Hinson JT. Cell Rep. 2021 May 4;35(5):109088. doi: 10.1016/j.celrep.2021.109088. PubMed
Cytomegalovirus infection of glioblastoma cells leads to NF-kappaB dependent upregulation of the c-MET oncogenic tyrosine kinase. Krenzlin H, Zdioruk M, Nowicki MO, Finkelberg T, Keric N, Lemmermann N, Skubal M, Chiocca EA, Cook CH, Lawler SE. Cancer Lett. 2021 Aug 10;513:26-35. doi: 10.1016/j.canlet.2021.05.005. Epub 2021 May 12. PubMed
Genetic manipulation of adhesion GPCR CD97/ADGRE5 modulates invasion in patient-derived glioma stem cells. Eichberg DG, Slepak TI, Pascoini AL, Komotar RJ, Ivan ME. J Neurooncol. 2021 Jul;153(3):383-391. doi: 10.1007/s11060-021-03778-8. Epub 2021 May 24. PubMed
Convalescent-Phase Sera and Vaccine-Elicited Antibodies Largely Maintain Neutralizing Titer against Global SARS-CoV-2 Variant Spikes. Tada T, Dcosta BM, Samanovic MI, Herati RS, Cornelius A, Zhou H, Vaill A, Kazmierski W, Mulligan MJ, Landau NR. mBio. 2021 Jun 29;12(3):e0069621. doi: 10.1128/mBio.00696-21. Epub 2021 Jun 1. PubMed
CRISPR Interference (CRISPRi) and CRISPR Activation (CRISPRa) to Explore the Oncogenic lncRNA Network. Morelli E, Gulla' A, Amodio N, Taiana E, Neri A, Fulciniti M, Munshi NC. Methods Mol Biol. 2021;2348:189-204. doi: 10.1007/978-1-0716-1581-2_13. PubMed
IL-1B drives opposing responses in primary tumours and bone metastases; harnessing combination therapies to improve outcome in breast cancer. Tulotta C, Lefley DV, Moore CK, Amariutei AE, Spicer-Hadlington AR, Quayle LA, Hughes RO, Ahmed K, Cookson V, Evans CA, Vadakekolathu J, Heath P, Francis S, Pinteaux E, Pockley AG, Ottewell PD. NPJ Breast Cancer. 2021 Jul 21;7(1):95. doi: 10.1038/s41523-021-00305-w. PubMed
Regulation of telomere homeostasis and genomic stability in cancer by N (6)-adenosine methylation (m(6)A). Lee JH, Hong J, Zhang Z, de la Pena Avalos B, Proietti CJ, Deamicis AR, Guzman G P, Lam HM, Garcia J, Roudier MP, Sisk AE, De La Rosa R, Vu K, Yang M, Liao Y, Scheirer J, Pechacek D, Yadav P, Rao MK, Zheng S, Johnson-Pais TL, Leach RJ, Elizalde PV, Dray E, Xu K. Sci Adv. 2021 Jul 28;7(31). pii: 7/31/eabg7073. doi: 10.1126/sciadv.abg7073. Print 2021 Jul. PubMed
Actinin BioID reveals sarcomere crosstalk with oxidative metabolism through interactions with IGF2BP2. Ladha FA, Thakar K, Pettinato AM, Legere N, Ghahremani S, Cohn R, Romano R, Meredith E, Chen YS, Hinson JT. Cell Rep. 2021 Aug 10;36(6):109512. doi: 10.1016/j.celrep.2021.109512. PubMed
TDO2 Was Downregulated in Hepatocellular Carcinoma and Inhibited Cell Proliferation by Upregulating the Expression of p21 and p27. Yu C, Rao D, Zhu H, Liu Q, Huang W, Zhang L, Liang H, Song J, Ding Z. Biomed Res Int. 2021 Aug 13;2021:4708439. doi: 10.1155/2021/4708439. eCollection 2021. PubMed
miR383 increases the cisplatin sensitivity of lung adenocarcinoma cells through inhibition of the RBM24mediated NFkappaB signaling pathway. He B, Wu C, Sun W, Qiu Y, Li J, Liu Z, Jing T, Wang H, Liao Y. Int J Oncol. 2021 Nov;59(5). pii: 87. doi: 10.3892/ijo.2021.5267. Epub 2021 Sep 24. PubMed
Labeling and measuring stressed mitochondria using a PINK1-based ratiometric fluorescent sensor. Uesugi R, Ishii S, Matsuura A, Itakura E. J Biol Chem. 2021 Nov;297(5):101279. doi: 10.1016/j.jbc.2021.101279. Epub 2021 Oct 5. PubMed
FCRL1 Regulates B Cell Receptor-Induced ERK Activation through GRB2. DeLuca JM, Murphy MK, Wang X, Wilson TJ. J Immunol. 2021 Dec 1;207(11):2688-2698. doi: 10.4049/jimmunol.2100218. Epub 2021 Oct 25. PubMed
Partial resistance of SARS-CoV-2 Delta variants to vaccine-elicited antibodies and convalescent sera. Tada T, Zhou H, Dcosta BM, Samanovic MI, Mulligan MJ, Landau NR. iScience. 2021 Nov 19;24(11):103341. doi: 10.1016/j.isci.2021.103341. Epub 2021 Oct 24. PubMed
Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs. Yarmarkovich M, Marshall QF, Warrington JM, Premaratne R, Farrel A, Groff D, Li W, di Marco M, Runbeck E, Truong H, Toor JS, Tripathi S, Nguyen S, Shen H, Noel T, Church NL, Weiner A, Kendsersky N, Martinez D, Weisberg R, Christie M, Eisenlohr L, Bosse KR, Dimitrov DS, Stevanovic S, Sgourakis NG, Kiefel BR, Maris JM. Nature. 2021 Nov;599(7885):477-484. doi: 10.1038/s41586-021-04061-6. Epub 2021 Nov 3. PubMed
GRAMD4 inhibits tumour metastasis by recruiting the E3 ligase ITCH to target TAK1 for degradation in hepatocellular carcinoma. Ge QY, Chen J, Li GX, Tan XL, Song J, Ning D, Mo J, Du PC, Liu QM, Liang HF, Ding ZY, Zhang XW, Zhang BX. Clin Transl Med. 2021 Nov;11(11):e635. doi: 10.1002/ctm2.635. PubMed
SARS-CoV-2 spike protein harnesses SNX27-mediated endocytic recycling pathway. Zhao L, Zhong K, Zhao J, Yong X, Tong A, Jia D. MedComm (2020). 2021 Oct 8. pii: MCO292. doi: 10.1002/mco2.92. PubMed
Functional analysis of the 1p34.3 risk locus implicates GNL2 in high-grade serous ovarian cancer. Nakamura K, Reid BM, Chen A, Chen Z, Goode EL, Permuth JB, Teer JK, Tyrer J, Yu X, Kanetsky PA, Pharoah PD, Gayther SA, Sellers TA, Lawrenson K, Karreth FA. Am J Hum Genet. 2022 Jan 6;109(1):116-135. doi: 10.1016/j.ajhg.2021.11.020. Epub 2021 Dec 28. PubMed
Stem cell-derived porcine macrophages as a new platform for studying host-pathogen interactions. Meek S, Watson T, Eory L, McFarlane G, Wynne FJ, McCleary S, Dunn LEM, Charlton EM, Craig C, Shih B, Regan T, Taylor R, Sutherland L, Gossner A, Chintoan-Uta C, Fletcher S, Beard PM, Hassan MA, Grey F, Hope JC, Stevens MP, Nowak-Imialek M, Niemann H, Ross PJ, Tait-Burkard C, Brown SM, Lefevre L, Thomson G, McColl BW, Lawrence AB, Archibald AL, Steinbach F, Crooke HR, Gao X, Liu P, Burdon T. BMC Biol. 2022 Jan 14;20(1):14. doi: 10.1186/s12915-021-01217-8. PubMed
Glucagon signaling via supraphysiologic GCGR can reduce cell viability without stimulating gluconeogenic gene expression in liver cancer cells. Godfrey J, Riscal R, Skuli N, Simon MC. Cancer Metab. 2022 Feb 5;10(1):4. doi: 10.1186/s40170-022-00280-1. PubMed
ASB17 Facilitates the Burst of LPS-Induced Inflammation Through Maintaining TRAF6 Stability. Wan P, Yang G, Zhang S, Zhang Y, Jia Y, Che X, Luo Z, Pan P, Li G, Chen X, Zhang Q, Zhang W, Tan Q, Li Y, Wu J. Front Cell Infect Microbiol. 2022 Jan 31;12:759077. doi: 10.3389/fcimb.2022.759077. eCollection 2022. PubMed
Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells. North K, Benbarche S, Liu B, Pangallo J, Chen S, Stahl M, Bewersdorf JP, Stanley RF, Erickson C, Cho H, Pineda JMB, Thomas JD, Polaski JT, Belleville AE, Gabel AM, Udy DB, Humbert O, Kiem HP, Abdel-Wahab O, Bradley RK. Nat Biotechnol. 2022 Jul;40(7):1103-1113. doi: 10.1038/s41587-022-01224-2. Epub 2022 Mar 3. PubMed
Neutralization of SARS-CoV-2 Variants by mRNA and Adenoviral Vector Vaccine-Elicited Antibodies. Tada T, Zhou H, Samanovic MI, Dcosta BM, Cornelius A, Herati RS, Mulligan MJ, Landau NR. Front Immunol. 2022 Mar 8;13:797589. doi: 10.3389/fimmu.2022.797589. eCollection 2022. PubMed
Impairment of SARS-CoV-2 spike glycoprotein maturation and fusion activity by nitazoxanide: an effect independent of spike variants emergence. Riccio A, Santopolo S, Rossi A, Piacentini S, Rossignol JF, Santoro MG. Cell Mol Life Sci. 2022 Apr 7;79(5):227. doi: 10.1007/s00018-022-04246-w. PubMed
A leukemia-protective germline variant mediates chromatin module formation via transcription factor nucleation. Llimos G, Gardeux V, Koch U, Kribelbauer JF, Hafner A, Alpern D, Pezoldt J, Litovchenko M, Russeil J, Dainese R, Moia R, Mahmoud AM, Rossi D, Gaidano G, Plass C, Lutsik P, Gerhauser C, Waszak SM, Boettiger A, Radtke F, Deplancke B. Nat Commun. 2022 Apr 19;13(1):2042. doi: 10.1038/s41467-022-29625-6. PubMed
Histone methyltransferase Dot1L recruits O-GlcNAc transferase to target chromatin sites to regulate histone O-GlcNAcylation. Xu B, Zhang C, Jiang A, Zhang X, Liang F, Wang X, Li D, Liu C, Liu X, Xia J, Li Y, Wang Y, Yang Z, Chen J, Zhou Y, Chen L, Sun H. J Biol Chem. 2022 Jul;298(7):102115. doi: 10.1016/j.jbc.2022.102115. Epub 2022 Jun 9. PubMed
Tumor-derived CTF1 (cardiotrophin 1) is a critical mediator of stroma-assisted and autophagy-dependent breast cancer cell migration, invasion and metastasis. Akkoc Y, Dalci K, Karakas HE, Erbil-Bilir S, Yalav O, Sakman G, Celik F, Arikan S, Zeybek U, Ergin M, Akkiz H, Dilege E, Dengjel J, Dogan-Ekici AI, Gozuacik D. Autophagy. 2022 Jun 28:1-18. doi: 10.1080/15548627.2022.2090693. PubMed
Hypoxia-inducible lentiviral gene expression in engineered human macrophages. Chinn HK, Gardell JL, Matsumoto LR, Labadie KP, Mihailovic TN, Lieberman NAP, Davis A, Pillarisetty VG, Crane CA. J Immunother Cancer. 2022 Jun;10(6). pii: jitc-2021-003770. doi: 10.1136/jitc-2021-003770. PubMed
Resistance of SARS-CoV-2 Omicron BA.1 and BA.2 Variants to Vaccine-Elicited Sera and Therapeutic Monoclonal Antibodies. Zhou H, Dcosta BM, Landau NR, Tada T. Viruses. 2022 Jun 18;14(6). pii: v14061334. doi: 10.3390/v14061334. PubMed
Genome-scale CRISPR-Cas9 screen reveals novel regulators of B7-H3 in tumor cells. Zhao S, Wang Y, Yang N, Mu M, Wu Z, Li H, Tang X, Zhong K, Zhang Z, Huang C, Cao T, Zheng M, Wang G, Nie C, Yang H, Guo G, Zhou L, Zheng X, Tong A. J Immunother Cancer. 2022 Jun;10(6). pii: jitc-2022-004875. doi: 10.1136/jitc-2022-004875. PubMed
SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation. Xu Z, Choi JH, Dai DL, Luo J, Ladak RJ, Li Q, Wang Y, Zhang C, Wiebe S, Liu ACH, Ran X, Yang J, Naeli P, Garzia A, Zhou L, Mahmood N, Deng Q, Elaish M, Lin R, Mahal LK, Hobman TC, Pelletier J, Alain T, Vidal SM, Duchaine T, Mazhab-Jafari MT, Mao X, Jafarnejad SM, Sonenberg N. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2204539119. doi: 10.1073/pnas.2204539119. Epub 2022 Jul 25. PubMed
Silver Nanoparticles Selectively Treat Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumors in a Neurofibromin-Dependent Manner. Alewine G, Knight J, Ghantae A, Mamrega C, Attiah B, Coover RA, Fahrenholtz CD. J Pers Med. 2022 Jun 30;12(7):1080. doi: 10.3390/jpm12071080. PubMed
Pan-cancer analysis combined with experimental validation revealed IL4I1 as an immunological and prognostic biomarker. Rao D, Yu C, Wang T, Sheng J, Lv E, Liang H, Huang W, Dong H. Int Immunopharmacol. 2022 Oct;111:109091. doi: 10.1016/j.intimp.2022.109091. Epub 2022 Aug 8. PubMed
Directly injected lentiviral vector-based T cell vaccine protects mice against acute and chronic viral infection. Tada T, Norton TD, Leibowitz R, Landau NR. JCI Insight. 2022 Sep 22;7(18):e161598. doi: 10.1172/jci.insight.161598. PubMed
SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression. Casteels T, Bajew S, Reinis J, Enders L, Schuster M, Fontaine F, Muller AC, Wagner BK, Bock C, Kubicek S. Cell Rep. 2022 Aug 30;40(9):111288. doi: 10.1016/j.celrep.2022.111288. PubMed
Human NOP2/NSUN1 regulates ribosome biogenesis through non-catalytic complex formation with box C/D snoRNPs. Liao H, Gaur A, McConie H, Shekar A, Wang K, Chang JT, Breton G, Denicourt C. Nucleic Acids Res. 2022 Oct 14;50(18):10695-10716. doi: 10.1093/nar/gkac817. PubMed
Androgen receptor activity in prostate cancer dictates efficacy of bipolar androgen therapy through MYC. Sena LA, Kumar R, Sanin DE, Thompson EA, Rosen DM, Dalrymple SL, Antony L, Yang Y, Gomes-Alexandre C, Hicks JL, Jones T, Bowers KA, Eskra JN, Meyers J, Gupta A, Skaist A, Yegnasubramanian S, Luo J, Brennen WN, Kachhap SK, Antonarakis ES, De Marzo AM, Isaacs JT, Markowski MC, Denmeade SR. J Clin Invest. 2022 Dec 1;132(23):e162396. doi: 10.1172/JCI162396. PubMed
Immune infiltration landscape on prognosis and therapeutic response and relevant epigenetic and transcriptomic mechanisms in lung adenocarcinoma. Zhang L, Jiang B, Lan Z, Yang C, Yao Y, Lin J, Wei Q. Front Immunol. 2022 Oct 6;13:983570. doi: 10.3389/fimmu.2022.983570. eCollection 2022. PubMed
An Engineered Paper-Based 3D Coculture Model of Pancreatic Cancer to Study the Impact of Tissue Architecture and Microenvironmental Gradients on Cell Phenotype. Cadavid JL, Latour S, Nowlan F, Co IL, Landon-Brace N, Wouters BG, Grunwald BT, Nitz M, Jackson HW, McGuigan AP. Adv Healthc Mater. 2022 Oct 29:e2201846. doi: 10.1002/adhm.202201846. PubMed
High p62 expression suppresses the NLRP1 inflammasome and increases stress resistance in cutaneous SCC cells. Hennig P, Di Filippo M, Bilfeld G, Mellett M, Beer HD. Cell Death Dis. 2022 Dec 29;13(12):1077. doi: 10.1038/s41419-022-05530-0. PubMed
Loss of CDKN2A cooperates with WWTR1(TAZ)-CAMTA1 gene fusion to promote tumor progression in epithelioid hemangioendothelioma. Seavey CN, Hallett A, Li S, Che K, Pobbati AV, Ma S, Burtscher A, Kanai R, Lamar JM, Rubin BP. Clin Cancer Res. 2023 Jan 4:CCR-22-2497. doi: 10.1158/1078-0432.CCR-22-2497. PubMed
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction. Guo Y, Zhang H, Yan C, Shen B, Zhang Y, Guo X, Sun S, Yu F, Yan J, Liu R, Zhang Q, Zhang D, Liu H, Liu Y, Zhang Y, Li W, Qin J, Lv H, Wang Z, Yuan Y, Yang JF, Zhong YT, Gao S, Zhou B, Liu L, Kong D, Hao X, Hu J, Chen Q. Nat Chem Biol. 2023 Apr;19(4):468-477. doi: 10.1038/s41589-022-01224-y. Epub 2023 Jan 12. PubMed
CCPG1 recognizes endoplasmic reticulum luminal proteins for selective ER-phagy. Ishii S, Chino H, Ode KL, Kurikawa Y, Ueda HR, Matsuura A, Mizushima N, Itakura E. Mol Biol Cell. 2023 Apr 1;34(4):ar29. doi: 10.1091/mbc.E22-09-0432. Epub 2023 Feb 3. PubMed
Novel Local "Off-the-Shelf" Immunotherapy for the Treatment of Myeloma Bone Disease. Charvatova S, Motais B, Czapla J, Cichon T, Smolarczyk R, Walek Z, Giebel S, Hajek R, Bago JR. Cells. 2023 Jan 30;12(3):448. doi: 10.3390/cells12030448. PubMed
Restoration of mitochondrial function through activation of hypomodified tRNAs with pathogenic mutations associated with mitochondrial diseases. Tomoda E, Nagao A, Shirai Y, Asano K, Suzuki T, Battersby BJ, Suzuki T. Nucleic Acids Res. 2023 Aug 11;51(14):7563-7579. doi: 10.1093/nar/gkad139. PubMed
STING Protein-Based In Situ Vaccine Synergizes CD4(+) T, CD8(+) T, and NK Cells for Tumor Eradication. He Y, Hong C, Huang S, Kaskow JA, Covarrubias G, Pires IS, Sacane JC, Hammond PT, Belcher AM. Adv Healthc Mater. 2023 Apr 4:e2300688. doi: 10.1002/adhm.202300688. PubMed
An Automation Workflow for High-Throughput Manufacturing and Analysis of Scaffold-Supported 3D Tissue Arrays. Cao R, Li NT, Latour S, Cadavid JL, Tan CM, Forman A, Jackson HW, McGuigan AP. Adv Healthc Mater. 2023 Jul;12(19):e2202422. doi: 10.1002/adhm.202202422. Epub 2023 May 10. PubMed
Intracellular trafficking of HLA-E and its regulation. He W, Gea-Mallorqui E, Colin-York H, Fritzsche M, Gillespie GM, Brackenridge S, Borrow P, McMichael AJ. J Exp Med. 2023 Aug 7;220(8):e20221941. doi: 10.1084/jem.20221941. Epub 2023 May 4. PubMed
Syngeneic mouse model of human HER2+ metastatic breast cancer for the evaluation of trastuzumab emtansine combined with oncolytic rhabdovirus. Taha Z, Crupi MJF, Alluqmani N, Fareez F, Ng K, Sobh J, Lee E, Chen A, Thomson M, Spinelli MM, Ilkow CS, Bell JC, Arulanandam R, Diallo JS. Front Immunol. 2023 Apr 19;14:1181014. doi: 10.3389/fimmu.2023.1181014. eCollection 2023. PubMed
Salt-inducible kinase inhibition promotes the adipocyte thermogenic program and adipose tissue browning. Shi F, de Fatima Silva F, Liu D, Patel HU, Xu J, Zhang W, Turk C, Kruger M, Collins S. Mol Metab. 2023 Aug;74:101753. doi: 10.1016/j.molmet.2023.101753. Epub 2023 Jun 13. PubMed
m(6)A Regulates the Stability of Cellular Transcripts Required for Efficient KSHV Lytic Replication. Manners O, Baquero-Perez B, Mottram TJ, Yonchev ID, Trevelyan CJ, Harper KL, Menezes S, Patterson MR, Macdonald A, Wilson SA, Aspden JL, Whitehouse A. Viruses. 2023 Jun 16;15(6):1381. doi: 10.3390/v15061381. PubMed
beta(2)-AR inhibition enhances EGFR antibody efficacy hampering the oxidative stress response machinery. Del Vecchio V, Mele L, Panda SK, Sanchez-Pajares IR, Mosca L, Tirino V, Barbieri M, Bruzzese F, Luciano A, Marino FZ, Accardo M, Nicoletti GF, Papaccio G, Barbieri A, Desiderio V. Cell Death Dis. 2023 Sep 19;14(9):613. doi: 10.1038/s41419-023-06129-9. PubMed
Nanobody-based pannexin1 channel inhibitors reduce inflammation in acute liver injury. Van Campenhout R, De Groof TWM, Kadam P, Kwak BR, Muyldermans S, Devoogdt N, Vinken M. J Nanobiotechnology. 2023 Oct 11;21(1):371. doi: 10.1186/s12951-023-02137-1. PubMed
Rewiring of the promoter-enhancer interactome and regulatory landscape in glioblastoma orchestrates gene expression underlying neurogliomal synaptic communication. Chakraborty C, Nissen I, Vincent CA, Hagglund AC, Hornblad A, Remeseiro S. Nat Commun. 2023 Oct 13;14(1):6446. doi: 10.1038/s41467-023-41919-x. PubMed
Targeting of intracellular oncoproteins with peptide-centric CARs. Yarmarkovich M, Marshall QF, Warrington JM, Premaratne R, Farrel A, Groff D, Li W, di Marco M, Runbeck E, Truong H, Toor JS, Tripathi S, Nguyen S, Shen H, Noel T, Church NL, Weiner A, Kendsersky N, Martinez D, Weisberg R, Christie M, Eisenlohr L, Bosse KR, Dimitrov DS, Stevanovic S, Sgourakis NG, Kiefel BR, Maris JM. Nature. 2023 Nov;623(7988):820-827. doi: 10.1038/s41586-023-06706-0. Epub 2023 Nov 8. PubMed
A Novel Metastatic Estrogen Receptor-Expressing Breast Cancer Model with Antiestrogen Responsiveness. Langsten KL, Shi L, Wilson AS, Lumia S, Westwood B, Skeen AM, Xie MT, Surratt VE, Turner J, Langefeld CD, Singh R, Cook KL, Kerr BA. Cancers (Basel). 2023 Dec 9;15(24):5773. doi: 10.3390/cancers15245773. PubMed
A FACS-based novel isolation technique identifies heterogeneous CTCs in oral squamous cell carcinoma. Chauhan A, Pal A, Sachdeva M, Boora GS, Parsana M, Bakshi J, Verma RK, Srinivasan R, Chatterjee D, Maitra A, Ghoshal S. Front Oncol. 2024 Feb 26;14:1269211. doi: 10.3389/fonc.2024.1269211. eCollection 2024. PubMed
Protocol for the isolation of tumor cell-derived extracellular vesicles followed by in vivo metastasis assessment in a murine ovarian cancer model. Mittal S, Kumar S, Gupta P, Singh M, Chaluvally-Raghavan P, Pradeep S. STAR Protoc. 2024 Jun 21;5(2):102943. doi: 10.1016/j.xpro.2024.102943. Epub 2024 Mar 11. PubMed
Silver Nanoparticles Selectively Treat Neurofibromatosis Type 1-Associated Plexiform Neurofibroma Cells at Doses That Do Not Affect Patient-Matched Schwann Cells. Attiah B, Alewine G, Easter MK, Coover RA, Fahrenholtz CD. Pharmaceutics. 2024 Mar 7;16(3):371. doi: 10.3390/pharmaceutics16030371. PubMed
The Role of Heat-Induced Stress Granules in the Blood-Testis Barrier of Mice. Zhao Z, Cai Y, Lin X, Liu N, Qin Y, Wu Y. Int J Mol Sci. 2024 Mar 25;25(7):3637. doi: 10.3390/ijms25073637. PubMed
Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages. Mandula JK, Sierra-Mondragon RA, Jimenez RV, Chang D, Mohamed E, Chang S, Vazquez-Martinez JA, Cao Y, Anadon CM, Lee SB, Das S, Rocha-Munguba L, Pham VM, Li R, Tarhini AA, Furqan M, Dalton W, Churchman M, Moran-Segura CM, Nguyen J, Perez B, Kojetin DJ, Obermayer A, Yu X, Chen A, Shaw TI, Conejo-Garcia JR, Rodriguez PC. Immunity. 2024 May 14;57(5):1124-1140.e9. doi: 10.1016/j.immuni.2024.03.020. Epub 2024 Apr 17. PubMed
Modulation of alveolar macrophage and mitochondrial fitness by medicinal plant-derived nanovesicles to mitigate acute lung injury and viral pneumonia. Ye L, Gao Y, Mok SWF, Liao W, Wang Y, Chen C, Yang L, Zhang J, Shi L. J Nanobiotechnology. 2024 Apr 18;22(1):190. doi: 10.1186/s12951-024-02473-w. PubMed
MAPK-mediated PHGDH induction is essential for melanoma formation and represents an actionable vulnerability. Jasani N, Xu X, Posorske B, Kim Y, Vera O, Tsai KY, DeNicola GM, Karreth FA. bioRxiv [Preprint]. 2024 Apr 15:2024.04.11.589139. doi: 10.1101/2024.04.11.589139. PubMed
NAB2-STAT6 drives an EGR1-dependent neuroendocrine program in Solitary Fibrous Tumors. Hill CM, Indeglia A, Picone F, Murphy ME, Cipriano C, Maki RG, Gardini A. bioRxiv [Preprint]. 2024 Apr 20:2024.04.15.589533. doi: 10.1101/2024.04.15.589533. PubMed
DDX18 Facilitates the Tumorigenesis of Lung Adenocarcinoma by Promoting Cell Cycle Progression through the Upregulation of CDK4. Feng B, Wang X, Qiu D, Sun H, Deng J, Tan Y, Ji K, Xu S, Zhang S, Tang C. Int J Mol Sci. 2024 May 1;25(9):4953. doi: 10.3390/ijms25094953. PubMed
Mitochondrial respiratory function is preserved under cysteine starvation via glutathione catabolism in NSCLC. Ward NP, Yoon SJ, Flynn T, Sherwood AM, Olley MA, Madej J, DeNicola GM. Nat Commun. 2024 May 18;15(1):4244. doi: 10.1038/s41467-024-48695-2. PubMed
DNMT3B splicing dysregulation mediated by SMCHD1 loss contributes to DUX4 overexpression and FSHD pathogenesis. Engal E, Sharma A, Aviel U, Taqatqa N, Juster S, Jaffe-Herman S, Bentata M, Geminder O, Gershon A, Lewis R, Kay G, Hecht M, Epsztejn-Litman S, Gotkine M, Mouly V, Eiges R, Salton M, Drier Y. Sci Adv. 2024 May 31;10(22):eadn7732. doi: 10.1126/sciadv.adn7732. Epub 2024 May 29. PubMed
Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells. Capdevila C, Miller J, Cheng L, Kornberg A, George JJ, Lee H, Botella T, Moon CS, Murray JW, Lam S, Calderon RI, Malagola E, Whelan G, Lin CS, Han A, Wang TC, Sims PA, Yan KS. Cell. 2024 Jun 6;187(12):3039-3055.e14. doi: 10.1016/j.cell.2024.05.001. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.