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- Eric Verdin
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SIRT2 Flag Citations (27)
Originally described in: The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase.North BJ, Marshall BL, Borra MT, Denu JM, Verdin E Mol Cell. 2003 Feb . 11(2):437-44. PubMed Journal
Articles Citing SIRT2 Flag
Showing 1 to 10 of 27 entries
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Tau induces inflammasome activation and microgliosis through acetylating NLRP3. Zhang L, Gai Y, Liu Y, Meng D, Zeng Y, Luo Y, Zhang H, Wang Z, Yang M, Li Y, Liu Y, Lai Y, Yang J, Wu G, Chen Y, Zhu J, Liu S, Yu T, Zeng J, Wang J, Zhu D, Wang X, Lan X, Liu R. Clin Transl Med. 2024 Mar;14(3):e1623. doi: 10.1002/ctm2.1623. PubMed |
Neural deficits in a mouse model of PACS1 syndrome are corrected with PACS1- or HDAC6-targeting therapy. Villar-Pazos S, Thomas L, Yang Y, Chen K, Lyles JB, Deitch BJ, Ochaba J, Ling K, Powers B, Gingras S, Kordasiewicz HB, Grubisha MJ, Huang YH, Thomas G. Nat Commun. 2023 Oct 17;14(1):6547. doi: 10.1038/s41467-023-42176-8. PubMed |
RNA-targeted therapy corrects neuronal deficits in PACS1 syndrome mice. Thomas G, Villar-Pazos S, Thomas L, Yang Y, Chen K, Lyles J, Deitch B, Ochaba J, Ling K, Powers B, Gingras S, Kordasiewicz H, Grubisha M, Huang Y. Res Sq. 2023 Jan 27:rs.3.rs-2440581. doi: 10.21203/rs.3.rs-2440581/v1. Preprint. PubMed |
Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43. Garcia Morato J, Hans F, von Zweydorf F, Feederle R, Elsasser SJ, Skodras AA, Gloeckner CJ, Buratti E, Neumann M, Kahle PJ. Nat Commun. 2022 Mar 9;13(1):1223. doi: 10.1038/s41467-022-28822-7. PubMed |
Interplay between protein acetylation and ubiquitination controls MCL1 protein stability. Shimizu K, Gi M, Suzuki S, North BJ, Watahiki A, Fukumoto S, Asara JM, Tokunaga F, Wei W, Inuzuka H. Cell Rep. 2021 Nov 9;37(6):109988. doi: 10.1016/j.celrep.2021.109988. PubMed |
Profiling sirtuin activity using Copper-free click chemistry. Curry AM, Cohen I, Zheng S, Wohlfahrt J, White DS, Donu D, Cen Y. Bioorg Chem. 2021 Dec;117:105413. doi: 10.1016/j.bioorg.2021.105413. Epub 2021 Oct 8. PubMed |
SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation. Minten EV, Kapoor-Vazirani P, Li C, Zhang H, Balakrishnan K, Yu DS. Cell Rep. 2021 Mar 30;34(13):108921. doi: 10.1016/j.celrep.2021.108921. PubMed |
SIRT1 decelerates morphological processing of oligodendrocyte cell lines and regulates the expression of cytoskeleton-related oligodendrocyte proteins. Hisahara S, Iwahara N, Matsushita T, Suzuki S, Matsumura A, Fujikura M, Yokokawa K, Saito T, Manabe T, Kawamata J, Horio Y, Shimohama S. Biochem Biophys Res Commun. 2021 Mar 26;546:7-14. doi: 10.1016/j.bbrc.2021.01.095. Epub 2021 Feb 5. PubMed |
Methods for studying human sirtuins with activity-based chemical probes. Zheng S, Wohlfahrt J, Cohen I, Cen Y. Methods Enzymol. 2020;633:251-269. doi: 10.1016/bs.mie.2019.11.004. Epub 2019 Nov 23. PubMed |
Cysteine thiol oxidation on SIRT2 regulates inflammation in obese mice with sepsis. Wang X, Buechler NL, Long DL, Furdui CM, Yoza BK, McCall CE, Vachharajani V. Inflammation. 2019 Feb;42(1):156-169. doi: 10.1007/s10753-018-0881-9. PubMed |
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