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pcDNA3-EGFP Citations (163)

Originally described in: Fluorescent Protein Plasmids
Unpublished

Articles Citing pcDNA3-EGFP

Articles
Geldanamycin anisimycins activate Rho and stimulate Rho- and ROCK-dependent actin stress fiber formation. Amiri A, Noei F, Feroz T, Lee JM. Mol Cancer Res. 2007 Sep;5(9):933-42. PubMed
Targeting the PI3K p110alpha isoform inhibits medulloblastoma proliferation, chemoresistance, and migration. Guerreiro AS, Fattet S, Fischer B, Shalaby T, Jackson SP, Schoenwaelder SM, Grotzer MA, Delattre O, Arcaro A. Clin Cancer Res. 2008 Nov 1;14(21):6761-9. doi: 10.1158/1078-0432.CCR-08-0385. PubMed
Conserved 3'-untranslated region sequences direct subcellular localization of chaperone protein mRNAs in neurons. Vuppalanchi D, Coleman J, Yoo S, Merianda TT, Yadhati AG, Hossain J, Blesch A, Willis DE, Twiss JL. J Biol Chem. 2010 Jun 4;285(23):18025-38. doi: 10.1074/jbc.M109.061333. Epub 2010 Mar 22. PubMed
The N terminus of a schistosome beta subunit regulates inactivation and current density of a Cav2 channel. Salvador-Recatala V, Greenberg RM. J Biol Chem. 2010 Nov 12;285(46):35878-88. doi: 10.1074/jbc.M110.144725. Epub 2010 Sep 7. PubMed
Polarized migration of lymphatic endothelial cells is critically dependent on podoplanin regulation of Cdc42. Navarro A, Perez RE, Rezaiekhaligh MH, Mabry SM, Ekekezie II. Am J Physiol Lung Cell Mol Physiol. 2011 Jan;300(1):L32-42. doi: 10.1152/ajplung.00171.2010. Epub 2010 Oct 29. PubMed
Role of Pax3 acetylation in the regulation of Hes1 and Neurog2. Ichi S, Boshnjaku V, Shen YW, Mania-Farnell B, Ahlgren S, Sapru S, Mansukhani N, McLone DG, Tomita T, Mayanil CS. Mol Biol Cell. 2011 Feb 15;22(4):503-12. doi: 10.1091/mbc.E10-06-0541. Epub 2010 Dec 17. PubMed
Mechanisms by which the inhibition of specific intracellular signaling pathways increase osteoblast proliferation on apatite surfaces. Yang S, Tian YS, Lee YJ, Yu FH, Kim HM. Biomaterials. 2011 Apr;32(11):2851-61. doi: 10.1016/j.biomaterials.2011.01.015. Epub 2011 Feb 1. PubMed
The sphingolipid degradation product trans-2-hexadecenal induces cytoskeletal reorganization and apoptosis in a JNK-dependent manner. Kumar A, Byun HS, Bittman R, Saba JD. Cell Signal. 2011 Jul;23(7):1144-52. doi: 10.1016/j.cellsig.2011.02.009. Epub 2011 Mar 6. PubMed
The RhoA-ROCK-PTEN pathway as a molecular switch for anchorage dependent cell behavior. Yang S, Kim HM. Biomaterials. 2012 Apr;33(10):2902-15. doi: 10.1016/j.biomaterials.2011.12.051. Epub 2012 Jan 13. PubMed
Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscles through a S1PR2/STAT3 signaling pathway. Loh KC, Leong WI, Carlson ME, Oskouian B, Kumar A, Fyrst H, Zhang M, Proia RL, Hoffman EP, Saba JD. PLoS One. 2012;7(5):e37218. doi: 10.1371/journal.pone.0037218. Epub 2012 May 14. PubMed
Orthobunyavirus entry into neurons and other mammalian cells occurs via clathrin-mediated endocytosis and requires trafficking into early endosomes. Hollidge BS, Nedelsky NB, Salzano MV, Fraser JW, Gonzalez-Scarano F, Soldan SS. J Virol. 2012 Aug;86(15):7988-8001. doi: 10.1128/JVI.00140-12. Epub 2012 May 23. PubMed
Identification of Akt-independent regulation of hepatic lipogenesis by mammalian target of rapamycin (mTOR) complex 2. Yuan M, Pino E, Wu L, Kacergis M, Soukas AA. J Biol Chem. 2012 Aug 24;287(35):29579-88. doi: 10.1074/jbc.M112.386854. Epub 2012 Jul 7. PubMed
PI3K p110alpha isoform-dependent Rho GTPase Rac1 activation mediates H2S-promoted endothelial cell migration via actin cytoskeleton reorganization. Zhang LJ, Tao BB, Wang MJ, Jin HM, Zhu YC. PLoS One. 2012;7(9):e44590. doi: 10.1371/journal.pone.0044590. Epub 2012 Sep 7. PubMed
Glioma cell growth inhibition following photochemical internalization enhanced non-viral PTEN gene transfection. Mathews MS, Shih EC, Zamora G, Sun CH, Cho SK, Kwon YJ, Hirschberg H. Lasers Surg Med. 2012 Nov;44(9):746-54. doi: 10.1002/lsm.22082. Epub 2012 Sep 27. PubMed
Axonal transport of neural membrane protein 35 mRNA increases axon growth. Merianda TT, Vuppalanchi D, Yoo S, Blesch A, Twiss JL. J Cell Sci. 2013 Jan 1;126(Pt 1):90-102. doi: 10.1242/jcs.107268. Epub 2012 Oct 24. PubMed
Low-Rac1 activity downregulates MC3T3-E1 osteoblastic cell motility on a nanoscale topography prepared on polystyrene substrates in vitro. Zheng L, Kim HM. J Biomed Mater Res A. 2013 Jun;101(6):1629-36. doi: 10.1002/jbm.a.34463. Epub 2012 Nov 27. PubMed
HSV activates Akt to trigger calcium release and promote viral entry: novel candidate target for treatment and suppression. Cheshenko N, Trepanier JB, Stefanidou M, Buckley N, Gonzalez P, Jacobs W, Herold BC. FASEB J. 2013 Jul;27(7):2584-99. doi: 10.1096/fj.12-220285. Epub 2013 Mar 18. PubMed
Analysis of URI nuclear interaction with RPB5 and components of the R2TP/prefoldin-like complex. Mita P, Savas JN, Ha S, Djouder N, Yates JR 3rd, Logan SK. PLoS One. 2013 May 8;8(5):e63879. doi: 10.1371/journal.pone.0063879. Print 2013. PubMed
Mahogunin ring finger-1 (MGRN1) suppresses chaperone-associated misfolded protein aggregation and toxicity. Chhangani D, Mishra A. Sci Rep. 2013;3:1972. doi: 10.1038/srep01972. PubMed
Development of a novel treatment for leukemia directed at tumor-associated mRNA splicing. Daines DA, Sun J, Uchakina ON, McKallip RJ. Leuk Res. 2013 Sep;37(9):1125-31. doi: 10.1016/j.leukres.2013.06.017. Epub 2013 Jul 3. PubMed
High SIRT1 expression is a negative prognosticator in pancreatic ductal adenocarcinoma. Stenzinger A, Endris V, Klauschen F, Sinn B, Lorenz K, Warth A, Goeppert B, Ehemann V, Muckenhuber A, Kamphues C, Bahra M, Neuhaus P, Weichert W. BMC Cancer. 2013 Oct 2;13:450. doi: 10.1186/1471-2407-13-450. PubMed
A novel role for inhibitor of apoptosis (IAP) proteins as regulators of endothelial barrier function by mediating RhoA activation. Hornburger MC, Mayer BA, Leonhardt S, Willer EA, Zahler S, Beyerle A, Rajalingam K, Vollmar AM, Furst R. FASEB J. 2014 Apr;28(4):1938-46. doi: 10.1096/fj.13-235754. Epub 2013 Dec 26. PubMed
Mutant PINK1 upregulates tyrosine hydroxylase and dopamine levels, leading to vulnerability of dopaminergic neurons. Zhou ZD, Refai FS, Xie SP, Ng SH, Chan CH, Ho PG, Zhang XD, Lim TM, Tan EK. Free Radic Biol Med. 2014 Mar;68:220-33. doi: 10.1016/j.freeradbiomed.2013.12.015. Epub 2013 Dec 25. PubMed
Insights into the mechanisms underlying the antiproliferative potential of a Co(II) coordination compound bearing 1,10-phenanthroline-5,6-dione: DNA and protein interaction studies. Luis DV, Silva J, Tomaz AI, de Almeida RF, Larguinho M, Baptista PV, Martins LM, Silva TF, Borralho PM, Rodrigues CM, Rodrigues AS, Pombeiro AJ, Fernandes AR. J Biol Inorg Chem. 2014 Aug;19(6):787-803. doi: 10.1007/s00775-014-1110-0. Epub 2014 Jan 31. PubMed
ROCK inhibition activates MCF-7 cells. Yang S, Kim HM. PLoS One. 2014 Feb 11;9(2):e88489. doi: 10.1371/journal.pone.0088489. eCollection 2014. PubMed
Bioluminescent imaging of HPV-positive oral tumor growth and its response to image-guided radiotherapy. Zhong R, Pytynia M, Pelizzari C, Spiotto M. Cancer Res. 2014 Apr 1;74(7):2073-81. doi: 10.1158/0008-5472.CAN-13-2993. Epub 2014 Feb 13. PubMed
Mahogunin ring finger 1 suppresses misfolded polyglutamine aggregation and cytotoxicity. Chhangani D, Nukina N, Kurosawa M, Amanullah A, Joshi V, Upadhyay A, Mishra A. Biochim Biophys Acta. 2014 Sep;1842(9):1472-84. doi: 10.1016/j.bbadis.2014.04.014. Epub 2014 Apr 24. PubMed
Ubiquitin ligase ITCH recruitment suppresses the aggregation and cellular toxicity of cytoplasmic misfolded proteins. Chhangani D, Upadhyay A, Amanullah A, Joshi V, Mishra A. Sci Rep. 2014 May 28;4:5077. doi: 10.1038/srep05077. PubMed
A general purification platform for toxic proteins based on intein trans-splicing. Shi C, Tarimala A, Meng Q, Wood DW. Appl Microbiol Biotechnol. 2014 Nov;98(22):9425-35. doi: 10.1007/s00253-014-6080-1. Epub 2014 Oct 9. PubMed
Experimental evaluation does not reveal a direct effect of microRNA from the callipyge locus on DLK1 expression. Cheng H, Xu X, Hadfield T, Cockett N, Charlier C, Georges M, Takeda H. BMC Genomics. 2014 Oct 30;15:944. doi: 10.1186/1471-2164-15-944. PubMed
Marking cells with infrared fluorescent proteins to preserve photoresponsiveness in the retina. Fyk-Kolodziej B, Hellmer CB, Ichinose T. Biotechniques. 2014 Nov 1;57(5):245-53. doi: 10.2144/000114228. eCollection 2014 Nov. PubMed

Associated Plasmids

Oligomeric state regulated trafficking of human platelet-activating factor acetylhydrolase type-II. Monillas ES, Caplan JL, Thevenin AF, Bahnson BJ. Biochim Biophys Acta. 2015 May;1854(5):469-75. doi: 10.1016/j.bbapap.2015.02.007. Epub 2015 Feb 20. PubMed
A new fluorescent based screening system for high throughput screening of drugs targeting HBV-core and HBsAg interaction. Suresh V, Krishnakumar KA, Asha VV. Biomed Pharmacother. 2015 Mar;70:305-16. doi: 10.1016/j.biopha.2015.02.002. Epub 2015 Feb 16. PubMed
Self-nanoemulsifying drug delivery systems as novel approach for pDNA drug delivery. Hauptstein S, Prufert F, Bernkop-Schnurch A. Int J Pharm. 2015 Jun 20;487(1-2):25-31. doi: 10.1016/j.ijpharm.2015.03.064. Epub 2015 Mar 31. PubMed
Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6. Hu YJ, Belaghzal H, Hsiao WY, Qi J, Bradner JE, Guertin DA, Sif S, Imbalzano AN. Nucleic Acids Res. 2015 Jun 27. pii: gkv645. PubMed
Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1. Sekiyama N, Arthanari H, Papadopoulos E, Rodriguez-Mias RA, Wagner G, Leger-Abraham M. Proc Natl Acad Sci U S A. 2015 Jul 13. pii: 201512118. PubMed
Zeta potential changing phosphorylated nanocomplexes for pDNA delivery. Bonengel S, Prufert F, Jelkmann M, Bernkop-Schnurch A. Int J Pharm. 2016 May 17;504(1-2):117-24. doi: 10.1016/j.ijpharm.2015.10.021. Epub 2016 Apr 2. PubMed
Inhibition of hERG potassium channel by the antiarrhythmic agent mexiletine and its metabolite m-hydroxymexiletine. Gualdani R, Tadini-Buoninsegni F, Roselli M, Defrenza I, Contino M, Colabufo NA, Lentini G. Pharmacol Res Perspect. 2015 Oct;3(5):e00160. doi: 10.1002/prp2.160. Epub 2015 Jul 31. PubMed
Mahogunin ring finger 1 confers cytoprotection against mutant SOD1 aggresomes and is defective in an ALS mouse model. Chhangani D, Endo F, Amanullah A, Upadhyay A, Watanabe S, Mishra R, Yamanaka K, Mishra A. Neurobiol Dis. 2016 Feb;86:16-28. doi: 10.1016/j.nbd.2015.11.017. Epub 2015 Nov 29. PubMed
Ibuprofen Induces Mitochondrial-Mediated Apoptosis Through Proteasomal Dysfunction. Upadhyay A, Amanullah A, Chhangani D, Joshi V, Mishra R, Mishra A. Mol Neurobiol. 2015 Dec 15. PubMed
Repurposing the CRISPR-Cas9 system for targeted DNA methylation. Vojta A, Dobrinic P, Tadic V, Bockor L, Korac P, Julg B, Klasic M, Zoldos V. Nucleic Acids Res. 2016 Mar 11. pii: gkw159. PubMed

Associated Plasmids

Identification of the subgenomic promoter of the coat protein gene of cucumber fruit mottle mosaic virus and development of a heterologous expression vector. Rhee SJ, Jang YJ, Lee GP. Arch Virol. 2016 Jun;161(6):1527-38. doi: 10.1007/s00705-016-2808-9. Epub 2016 Mar 15. PubMed
Genome Editing in Human Pluripotent Stem Cells. Smith C, Ye Z, Cheng L. Cold Spring Harb Protoc. 2016 Apr 1;2016(4):pdb.top086819. doi: 10.1101/pdb.top086819. PubMed
A Simplified Direct Lipid Mixing Lipoplex Preparation: Comparison of Liposomal-, Dimethylsulfoxide-, and Ethanol-Based Methods. Meisel JW, Gokel GW. Sci Rep. 2016 Jun 21;6:27662. doi: 10.1038/srep27662. PubMed
Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose. Chahal JS, Khan OF, Cooper CL, McPartlan JS, Tsosie JK, Tilley LD, Sidik SM, Lourido S, Langer R, Bavari S, Ploegh HL, Anderson DG. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):E4133-42. doi: 10.1073/pnas.1600299113. Epub 2016 Jul 5. PubMed
Cell-penetrating self-nanoemulsifying drug delivery systems (SNEDDS) for oral gene delivery. Mahmood A, Prufert F, Efiana NA, Ashraf MI, Hermann M, Hussain S, Bernkop-Schnurch A. Expert Opin Drug Deliv. 2016 Nov;13(11):1503-1512. Epub 2016 Aug 4. PubMed
TGR5 suppresses high glucose-induced upregulation of fibronectin and transforming growth factor-beta1 in rat glomerular mesangial cells by inhibiting RhoA/ROCK signaling. Xiong F, Li X, Yang Z, Wang Y, Gong W, Huang J, Chen C, Liu P, Huang H. Endocrine. 2016 Dec;54(3):657-670. Epub 2016 Jul 28. PubMed
Proteasomal Dysfunction Induced By Diclofenac Engenders Apoptosis Through Mitochondrial Pathway. Amanullah A, Upadhyay A, Chhangani D, Joshi V, Mishra R, Yamanaka K, Mishra A. J Cell Biochem. 2016 Aug 2. doi: 10.1002/jcb.25666. PubMed
Immune cell-specific transcriptional profiling highlights distinct molecular pathways controlled by Tob1 upon experimental autoimmune encephalomyelitis. Didonna A, Cekanaviciute E, Oksenberg JR, Baranzini SE. Sci Rep. 2016 Aug 22;6:31603. doi: 10.1038/srep31603. PubMed
Metformin Improves Ileal Epithelial Barrier Function in Interleukin-10 Deficient Mice. Xue Y, Zhang H, Sun X, Zhu MJ. PLoS One. 2016 Dec 21;11(12):e0168670. doi: 10.1371/journal.pone.0168670. eCollection 2016. PubMed
Lanosterol Suppresses the Aggregation and Cytotoxicity of Misfolded Proteins Linked with Neurodegenerative Diseases. Upadhyay A, Amanullah A, Mishra R, Kumar A, Mishra A. Mol Neurobiol. 2017 Jan 19. doi: 10.1007/s12035-016-0377-2. PubMed
AMPK improves gut epithelial differentiation and barrier function via regulating Cdx2 expression. Sun X, Yang Q, Rogers CJ, Du M, Zhu MJ. Cell Death Differ. 2017 May;24(5):819-831. doi: 10.1038/cdd.2017.14. Epub 2017 Feb 24. PubMed
Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening. Joung J, Konermann S, Gootenberg JS, Abudayyeh OO, Platt RJ, Brigham MD, Sanjana NE, Zhang F. Nat Protoc. 2017 Apr;12(4):828-863. doi: 10.1038/nprot.2017.016. Epub 2017 Mar 23. PubMed

Associated Plasmids

Genome Editing in Human Pluripotent Stem Cells. Carlson-Stevermer J, Saha K. Methods Mol Biol. 2017;1590:165-174. doi: 10.1007/978-1-4939-6921-0_12. PubMed
Evaluation of the Expression of Amyloid Precursor Protein and the Ratio of Secreted Amyloid Beta 42 to Amyloid Beta 40 in SH-SY5Y Cells Stably Transfected with Wild-Type, Single-Mutant and Double-Mutant Forms of the APP Gene for the Study of Alzheimer's Disease Pathology. Pahrudin Arrozi A, Shukri SNS, Wan Ngah WZ, Mohd Yusof YA, Ahmad Damanhuri MH, Makpol S. Appl Biochem Biotechnol. 2017 Apr 17. doi: 10.1007/s12010-017-2468-6. PubMed
Zeta-potential-changing nanoparticles conjugated with cell-penetrating peptides for enhanced transfection efficiency. Suchaoin W, Mahmood A, Netsomboon K, Bernkop-Schnurch A. Nanomedicine (Lond). 2017 May;12(9):963-975. doi: 10.2217/nnm-2016-0345. Epub 2017 Apr 25. PubMed
YAP regulates cell mechanics by controlling focal adhesion assembly. Nardone G, Oliver-De La Cruz J, Vrbsky J, Martini C, Pribyl J, Skladal P, Pesl M, Caluori G, Pagliari S, Martino F, Maceckova Z, Hajduch M, Sanz-Garcia A, Pugno NM, Stokin GB, Forte G. Nat Commun. 2017 May 15;8:15321. doi: 10.1038/ncomms15321. PubMed
Recurrent rhinovirus infections in a child with inherited MDA5 deficiency. Lamborn IT, Jing H, Zhang Y, Drutman SB, Abbott JK, Munir S, Bade S, Murdock HM, Santos CP, Brock LG, Masutani E, Fordjour EY, McElwee JJ, Hughes JD, Nichols DP, Belkadi A, Oler AJ, Happel CS, Matthews HF, Abel L, Collins PL, Subbarao K, Gelfand EW, Ciancanelli MJ, Casanova JL, Su HC. J Exp Med. 2017 Jul 3;214(7):1949-1972. doi: 10.1084/jem.20161759. Epub 2017 Jun 12. PubMed
Indomethacin Elicits Proteasomal Dysfunctions Develops Apoptosis Through Mitochondrial Abnormalities. Amanullah A, Mishra R, Upadhyay A, Reddy PP, Das R, Mishra A. J Cell Physiol. 2017 Jul 6. doi: 10.1002/jcp.26081. PubMed
Engineering of monobody conjugates for human EphA2-specific optical imaging. Kim MA, Yoon HS, Park SH, Kim DY, Pyo A, Kim HS, Min JJ, Hong Y. PLoS One. 2017 Jul 7;12(7):e0180786. doi: 10.1371/journal.pone.0180786. eCollection 2017. PubMed
Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma. Huang J, Chen M, Whitley MJ, Kuo HC, Xu ES, Walens A, Mowery YM, Van Mater D, Eward WC, Cardona DM, Luo L, Ma Y, Lopez OM, Nelson CE, Robinson-Hamm JN, Reddy A, Dave SS, Gersbach CA, Dodd RD, Kirsch DG. Nat Commun. 2017 Jul 10;8:15999. doi: 10.1038/ncomms15999. PubMed
Ceramide activation of RhoA/Rho kinase impairs actin polymerization during aggregated LDL catabolism. Singh RK, Haka AS, Brumfield A, Grosheva I, Bhardwaj P, Chin HF, Xiong Y, Hla T, Maxfield FR. J Lipid Res. 2017 Oct;58(10):1977-1987. doi: 10.1194/jlr.M076398. Epub 2017 Aug 16. PubMed
Dynamics of Natural Killer Cells Cytotoxicity in Microwell Arrays with Connecting Channels. Xu Y, Zhou S, Lam YW, Pang SW. Front Immunol. 2017 Aug 17;8:998. doi: 10.3389/fimmu.2017.00998. eCollection 2017. PubMed
MTA promotes chemotaxis and chemokinesis of immune cells through distinct calcium-sensing receptor signaling pathways. Chang F, Kim JM, Choi Y, Park K. Biomaterials. 2018 Jan;150:14-24. doi: 10.1016/j.biomaterials.2017.10.009. Epub 2017 Oct 4. PubMed
Entirely S-protected chitosan: A promising mucoadhesive excipient for metronidazole vaginal tablets. Lupo N, Fodor B, Muhammad I, Yaqoob M, Matuszczak B, Bernkop-Schnurch A. Acta Biomater. 2017 Dec;64:106-115. doi: 10.1016/j.actbio.2017.10.014. Epub 2017 Oct 10. PubMed
Galphas regulates Glucagon-Like Peptide 1 Receptor-mediated cyclic AMP generation at Rab5 endosomal compartment. Girada SB, Kuna RS, Bele S, Zhu Z, Chakravarthi NR, DiMarchi RD, Mitra P. Mol Metab. 2017 Oct;6(10):1173-1185. doi: 10.1016/j.molmet.2017.08.002. Epub 2017 Aug 10. PubMed
Synthetic regulatory RNAs selectively suppress the progression of bladder cancer. Zhuang C, Huang X, Zhuang C, Luo X, Zhang X, Cai Z, Gui Y. J Exp Clin Cancer Res. 2017 Oct 30;36(1):151. doi: 10.1186/s13046-017-0626-x. PubMed
Protein S-glutathionylation induced by hypoxia increases hypoxia-inducible factor-1alpha in human colon cancer cells. Jeon D, Park HJ, Kim HS. Biochem Biophys Res Commun. 2018 Jan 1;495(1):212-216. doi: 10.1016/j.bbrc.2017.11.018. Epub 2017 Nov 4. PubMed
Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity. Riquelme SA, Hopkins BD, Wolfe AL, DiMango E, Kitur K, Parsons R, Prince A. Immunity. 2017 Dec 19;47(6):1169-1181.e7. doi: 10.1016/j.immuni.2017.11.010. Epub 2017 Dec 12. PubMed
Overexpression of CXCR4 promotes invasion and migration of non-small cell lung cancer via EGFR and MMP-9. Zuo J, Wen M, Li S, Lv X, Wang L, Ai X, Lei M. Oncol Lett. 2017 Dec;14(6):7513-7521. doi: 10.3892/ol.2017.7168. Epub 2017 Oct 11. PubMed
The chemokine receptor CCR10 promotes inflammation-driven hepatocarcinogenesis via PI3K/Akt pathway activation. Wu Q, Chen JX, Chen Y, Cai LL, Wang XZ, Guo WH, Zheng JF. Cell Death Dis. 2018 Feb 14;9(2):232. doi: 10.1038/s41419-018-0267-9. PubMed
Molecular Insights into hERG Potassium Channel Blockade by Lubeluzole. Gualdani R, Cavalluzzi MM, Tadini-Buoninsegni F, Convertino M, Gailly P, Stary-Weinzinger A, Lentini G. Cell Physiol Biochem. 2018;45(6):2233-2245. doi: 10.1159/000488169. Epub 2018 Mar 10. PubMed
Structural basis for LeishIF4E-1 modulation by an interacting protein in the human parasite Leishmania major. Meleppattu S, Arthanari H, Zinoviev A, Boeszoermenyi A, Wagner G, Shapira M, Leger-Abraham M. Nucleic Acids Res. 2018 Apr 20;46(7):3791-3801. doi: 10.1093/nar/gky194. PubMed
Butyrate Inhibits Indices of Colorectal Carcinogenesis via Enhancing alpha-Ketoglutarate-Dependent DNA Demethylation of Mismatch Repair Genes. Sun X, Zhu MJ. Mol Nutr Food Res. 2018 May;62(10):e1700932. doi: 10.1002/mnfr.201700932. Epub 2018 Apr 26. PubMed
Lanthionine synthetase C-like protein 2 (LanCL2) is important for adipogenic differentiation. Dutta D, Lai KY, Reyes-Ordonez A, Chen J, van der Donk WA. J Lipid Res. 2018 Aug;59(8):1433-1445. doi: 10.1194/jlr.M085274. Epub 2018 Jun 7. PubMed
Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance. Kale J, Kutuk O, Brito GC, Andrews TS, Leber B, Letai A, Andrews DW. EMBO Rep. 2018 Sep;19(9). pii: embr.201745235. doi: 10.15252/embr.201745235. Epub 2018 Jul 9. PubMed
NADPH oxidase 5 promotes proliferation and fibrosis in human hepatic stellate cells. Andueza A, Garde N, Garcia-Garzon A, Ansorena E, Lopez-Zabalza MJ, Iraburu MJ, Zalba G, Martinez-Irujo JJ. Free Radic Biol Med. 2018 Oct;126:15-26. doi: 10.1016/j.freeradbiomed.2018.07.013. Epub 2018 Jul 21. PubMed
Novel role of Gialpha2 in cell migration: Downstream of PI3-kinase-AKT and Rac1 in prostate cancer cells. Caggia S, Chunduri H, Millena AC, Perkins JN, Venugopal SV, Vo BT, Li C, Tu Y, Khan SA. J Cell Physiol. 2018 Jan;234(1):802-815. doi: 10.1002/jcp.26894. Epub 2018 Aug 4. PubMed
Lethal Factor Domain-Mediated Delivery of Nurr1 Transcription Factor Enhances Tyrosine Hydroxylase Activity and Protects from Neurotoxin-Induced Degeneration of Dopaminergic Cells. Paliga D, Raudzus F, Leppla SH, Heumann R, Neumann S. Mol Neurobiol. 2018 Aug 18. pii: 10.1007/s12035-018-1311-6. doi: 10.1007/s12035-018-1311-6. PubMed
The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain. Cajigas I, Chakraborty A, Swyter KR, Luo H, Bastidas M, Nigro M, Morris ER, Chen S, VanGompel MJW, Leib D, Kohtz SJ, Martina M, Koh S, Ay F, Kohtz JD. Mol Cell. 2018 Sep 20;71(6):956-972.e9. doi: 10.1016/j.molcel.2018.07.024. Epub 2018 Aug 23. PubMed
Colloidally Stable Small Unilamellar Stearyl Amine Lipoplexes for Effective BMP-9 Gene Delivery to Stem Cells for Osteogenic Differentiation. Vhora I, Lalani R, Bhatt P, Patil S, Patel H, Patel V, Misra A. AAPS PharmSciTech. 2018 Nov;19(8):3550-3560. doi: 10.1208/s12249-018-1161-6. Epub 2018 Sep 5. PubMed
Delivery of pDNA Polyplexes to Bronchial and Alveolar Epithelial Cells Using a Mesh Nebulizer. Gomes Dos Reis L, Svolos M, Moir LM, Jaber R, Windhab N, Young PM, Traini D. Pharm Res. 2018 Nov 15;36(1):14. doi: 10.1007/s11095-018-2542-y. PubMed
Evaluation and optimisation of unnatural amino acid incorporation and bioorthogonal bioconjugation for site-specific fluorescent labelling of proteins expressed in mammalian cells. Jakob L, Gust A, Grohmann D. Biochem Biophys Rep. 2018 Nov 6;17:1-9. doi: 10.1016/j.bbrep.2018.10.011. eCollection 2019 Mar. PubMed
HDAC1 interacts with the p50 NF-?B subunit via its nuclear localization sequence to constrain inflammatory gene expression. Cartwright TN, Worrell JC, Marchetti L, Dowling CM, Knox A, Kiely P, Mann J, Mann DA, Wilson CL. Biochim Biophys Acta Gene Regul Mech. 2018 Oct;1861(10):962-970. doi: 10.1016/j.bbagrm.2018.09.001. Epub 2018 Sep 10. PubMed
Highly mucus permeating and zeta potential changing self-emulsifying drug delivery systems: A potent gene delivery model for causal treatment of cystic fibrosis. Griesser J, Hetenyi G, Federer C, Steinbring C, Ellemunter H, Niedermayr K, Bernkop-Schnurch A. Int J Pharm. 2019 Feb 25;557:124-134. doi: 10.1016/j.ijpharm.2018.12.048. Epub 2018 Dec 27. PubMed
Knockdown of KDM2A inhibits proliferation associated with TGF-beta expression in HEK293T cell. Xu WH, Liang DY, Wang Q, Shen J, Liu QH, Peng YB. Mol Cell Biochem. 2019 Jan 2. pii: 10.1007/s11010-018-03493-5. doi: 10.1007/s11010-018-03493-5. PubMed
Nanotoxicologic Effects of PLGA Nanoparticles Formulated with a Cell-Penetrating Peptide: Searching for a Safe pDNA Delivery System for the Lungs. Gomes Dos Reis L, Lee WH, Svolos M, Moir LM, Jaber R, Windhab N, Young PM, Traini D. Pharmaceutics. 2019 Jan 3;11(1). pii: pharmaceutics11010012. doi: 10.3390/pharmaceutics11010012. PubMed
The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy. Mehto S, Jena KK, Nath P, Chauhan S, Kolapalli SP, Das SK, Sahoo PK, Jain A, Taylor GA, Chauhan S. Mol Cell. 2019 Feb 7;73(3):429-445.e7. doi: 10.1016/j.molcel.2018.11.018. Epub 2019 Jan 3. PubMed
Substrate mechanics controls adipogenesis through YAP phosphorylation by dictating cell spreading. Oliver-De La Cruz J, Nardone G, Vrbsky J, Pompeiano A, Perestrelo AR, Capradossi F, Melajova K, Filipensky P, Forte G. Biomaterials. 2019 Jun;205:64-80. doi: 10.1016/j.biomaterials.2019.03.009. Epub 2019 Mar 16. PubMed
Genetic and pharmacological inhibition of acid ceramidase prevents asymmetric cell division by neosis. White-Gilbertson S, Lu P, Norris JS, Voelkel-Johnson C. J Lipid Res. 2019 Jul;60(7):1225-1235. doi: 10.1194/jlr.M092247. Epub 2019 Apr 15. PubMed
The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration. Sala D, Cunningham TJ, Stec MJ, Etxaniz U, Nicoletti C, Dall'Agnese A, Puri PL, Duester G, Latella L, Sacco A. Nat Commun. 2019 Apr 17;10(1):1796. doi: 10.1038/s41467-019-09746-1. PubMed
The priming factor CAPS1 regulates dense-core vesicle acidification by interacting with rabconnectin3beta/WDR7 in neuroendocrine cells. Crummy E, Mani M, Thellman JC, Martin TFJ. J Biol Chem. 2019 Jun 14;294(24):9402-9415. doi: 10.1074/jbc.RA119.007504. Epub 2019 Apr 19. PubMed
Nonmuscle Myosin Heavy Chain IIA Recognizes Sialic Acids on Sialylated RNA Viruses To Suppress Proinflammatory Responses via the DAP12-Syk Pathway. Liu Y, Li R, Chen XX, Zhi Y, Deng R, Zhou EM, Qiao S, Zhang G. MBio. 2019 May 7;10(3). pii: mBio.00574-19. doi: 10.1128/mBio.00574-19. PubMed
Natural killer cell migration control in microchannels by perturbations and topography. Xu Y, Pang SW. Lab Chip. 2019 Jul 21;19(14):2466-2475. doi: 10.1039/c9lc00356h. Epub 2019 Jun 21. PubMed
A Synthetic Light-switchable System based on CRISPR Cas13a Regulates the Expression of LncRNA MALAT1 and Affects the Malignant Phenotype of Bladder Cancer Cells. Qi F, Tan B, Ma F, Zhu B, Zhang L, Liu X, Li H, Yang J, Cheng B. Int J Biol Sci. 2019 Jun 4;15(8):1630-1636. doi: 10.7150/ijbs.33772. eCollection 2019. PubMed
The Therapeutic Implications of Tea Polyphenols Against Dopamine (DA) Neuron Degeneration in Parkinson's Disease (PD). Zhou ZD, Xie SP, Saw WT, Ho PGH, Wang H, Lei Z, Yi Z, Tan EK. Cells. 2019 Aug 16;8(8). pii: cells8080911. doi: 10.3390/cells8080911. PubMed
SNARE proteins rescue impaired autophagic flux in Down syndrome. Aivazidis S, Jain A, Rauniyar AK, Anderson CC, Marentette JO, Orlicky DJ, Fritz KS, Harris PS, Siegel D, Maclean KN, Roede JR. PLoS One. 2019 Nov 12;14(11):e0223254. doi: 10.1371/journal.pone.0223254. eCollection 2019. PubMed
Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex. Qu Y, Hahn I, Lees M, Parkin J, Voelzmann A, Dorey K, Rathbone A, Friel CT, Allan VJ, Okenve-Ramos P, Sanchez-Soriano N, Prokop A. Elife. 2019 Nov 13;8. pii: 50319. doi: 10.7554/eLife.50319. PubMed
Quantum dots reveal heterogeneous membrane diffusivity and dynamic surface density polarization of dopamine transporter. Kovtun O, Tomlinson ID, Ferguson RS, Rosenthal SJ. PLoS One. 2019 Nov 21;14(11):e0225339. doi: 10.1371/journal.pone.0225339. eCollection 2019. PubMed
Biallelic ERBB3 loss-of-function variants are associated with a novel multisystem syndrome without congenital contracture. Li N, Xu Y, Zhang Y, Li G, Yu T, Yao R, Zhou Y, Shen Y, Yin L, Wang X, Wang J. Orphanet J Rare Dis. 2019 Nov 21;14(1):265. doi: 10.1186/s13023-019-1241-z. PubMed
Differential roles and activation of mammalian target of rapamycin complexes 1 and 2 during cell migration in prostate cancer cells. Venugopal SV, Caggia S, Gambrell-Sanders D, Khan SA. Prostate. 2020 Apr;80(5):412-423. doi: 10.1002/pros.23956. Epub 2020 Jan 29. PubMed
Pseudorabies Virus Infection of Epithelial Cells Leads to Persistent but Aberrant Activation of the NF-kappaB Pathway, Inhibiting Hallmark NF-kappaB-Induced Proinflammatory Gene Expression. Romero N, Van Waesberghe C, Favoreel HW. J Virol. 2020 May 4;94(10):e00196-20. doi: 10.1128/JVI.00196-20. Print 2020 May 4. PubMed
Ribosome profiling reveals a functional role for autophagy in mRNA translational control. Goldsmith J, Marsh T, Asthana S, Leidal AM, Suresh D, Olshen A, Debnath J. Commun Biol. 2020 Jul 17;3(1):388. doi: 10.1038/s42003-020-1090-2. PubMed
Replication Stress Induces Global Chromosome Breakage in the Fragile X Genome. Chakraborty A, Jenjaroenpun P, Li J, El Hilali S, McCulley A, Haarer B, Hoffman EA, Belak A, Thorland A, Hehnly H, Schildkraut CL, Chen CL, Kuznetsov VA, Feng W. Cell Rep. 2020 Sep 22;32(12):108179. doi: 10.1016/j.celrep.2020.108179. PubMed
A splice acceptor variant in HLA-DRA affects the conformation and cellular localization of the class II DR alpha-chain. Didonna A, Damotte V, Shams H, Matsunaga A, Caillier SJ, Dandekar R, Misra MK, Mofrad MRK, Oksenberg JR, Hollenbach JA. Immunology. 2021 Feb;162(2):194-207. doi: 10.1111/imm.13273. Epub 2020 Oct 19. PubMed
Nonviral Gene Delivery Embedded in Biomimetically Mineralized Matrices for Bone Tissue Engineering. Acri TM, Laird NZ, Jaidev LR, Meyerholz DK, Salem AK, Shin K. Tissue Eng Part A. 2021 Aug;27(15-16):1074-1083. doi: 10.1089/ten.TEA.2020.0206. Epub 2020 Nov 26. PubMed
CRISPR/Cas9-Constructed Pseudorabies Virus Mutants Reveal the Importance of UL13 in Alphaherpesvirus Escape from Genome Silencing. Van Cleemput J, Koyuncu OO, Laval K, Engel EA, Enquist LW. J Virol. 2021 Feb 24;95(6). pii: JVI.02286-20. doi: 10.1128/JVI.02286-20. Print 2021 Feb 24. PubMed
Ferroptosis induces membrane blebbing in placental trophoblasts. Kajiwara K, Beharier O, Chng CP, Goff JP, Ouyang Y, St Croix CM, Huang C, Kagan VE, Hsia KJ, Sadovsky Y. J Cell Sci. 2022 Mar 1;135(5). pii: jcs.255737. doi: 10.1242/jcs.255737. Epub 2021 Apr 20. PubMed
Design of an Imaging Probe to Monitor Real-Time Redistribution of L-type Voltage-Gated Calcium Channels in Astrocytic Glutamate Signaling. Tabatabaee MS, Kerkovius J, Menard F. Mol Imaging Biol. 2021 Jun;23(3):407-416. doi: 10.1007/s11307-020-01573-x. Epub 2021 Jan 12. PubMed
Cytoneme delivery of Sonic Hedgehog from ligand-producing cells requires Myosin 10 and a Dispatched-BOC/CDON co-receptor complex. Hall ET, Dillard ME, Stewart DP, Zhang Y, Wagner B, Levine RM, Pruett-Miller SM, Sykes A, Temirov J, Cheney RE, Mori M, Robinson CG, Ogden SK. Elife. 2021 Feb 11;10. pii: 61432. doi: 10.7554/eLife.61432. PubMed
Therapeutic potential of IBP as an autophagy inducer for treating lung cancer via blocking PAK1/Akt/mTOR signaling. Bu H, Tan S, Yuan B, Huang X, Jiang J, Wu Y, Jiang J, Li R. Mol Ther Oncolytics. 2020 Nov 4;20:82-93. doi: 10.1016/j.omto.2020.10.014. eCollection 2021 Mar 26. PubMed
Protease OMA1 modulates mitochondrial bioenergetics and ultrastructure through dynamic association with MICOS complex. Viana MP, Levytskyy RM, Anand R, Reichert AS, Khalimonchuk O. iScience. 2021 Jan 29;24(2):102119. doi: 10.1016/j.isci.2021.102119. eCollection 2021 Feb 19. PubMed

Associated Plasmids

mTORC1 promotes cell growth via m(6)A-dependent mRNA degradation. Cho S, Lee G, Pickering BF, Jang C, Park JH, He L, Mathur L, Kim SS, Jung S, Tang HW, Monette S, Rabinowitz JD, Perrimon N, Jaffrey SR, Blenis J. Mol Cell. 2021 May 20;81(10):2064-2075.e8. doi: 10.1016/j.molcel.2021.03.010. Epub 2021 Mar 22. PubMed
Embryonic exposure to hyper glucocorticoids suppresses brown fat development and thermogenesis via REDD1. Chen YT, Hu Y, Yang QY, Liu XD, Son JS, de Avila JM, Zhu MJ, Du M. Sci Bull (Beijing). 2021 Mar 15;66(5):478-489. doi: 10.1016/j.scib.2020.10.015. Epub 2020 Oct 28. PubMed
AAV-mediated YAP expression in cardiac fibroblasts promotes inflammation and increases fibrosis. Francisco J, Zhang Y, Nakada Y, Jeong JI, Huang CY, Ivessa A, Oka S, Babu GJ, Del Re DP. Sci Rep. 2021 May 18;11(1):10553. doi: 10.1038/s41598-021-89989-5. PubMed
PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR. Ghosh S, Nataraj NB, Noronha A, Patkar S, Sekar A, Mukherjee S, Winograd-Katz S, Kramarski L, Verma A, Lindzen M, Garcia DD, Green J, Eisenberg G, Gil-Henn H, Basu A, Lender Y, Weiss S, Oren M, Lotem M, Geiger B, Ruppin E, Yarden Y. Cell Rep. 2021 May 25;35(8):109181. doi: 10.1016/j.celrep.2021.109181. PubMed
Survey of cancer cell anatomy in nonadhesive confinement reveals a role for filamin-A and fascin-1 in leader bleb-based migration. Adams G Jr, Lopez MP, Cartagena-Rivera AX, Waterman CM. Mol Biol Cell. 2021 Aug 19;32(18):1772-1791. doi: 10.1091/mbc.E21-04-0174. Epub 2021 Jul 14. PubMed
The oncogenic transcription factor FUS-CHOP can undergo nuclear liquid-liquid phase separation. Owen I, Yee D, Wyne H, Perdikari TM, Johnson V, Smyth J, Kortum R, Fawzi NL, Shewmaker F. J Cell Sci. 2021 Sep 1;134(17). pii: 272045. doi: 10.1242/jcs.258578. Epub 2021 Sep 3. PubMed
Mechanical Stimulation after Centrifuge-Free Nano-Electroporative Transfection Is Efficient and Maintains Long-Term T Cell Functionalities. Tay A, Melosh N. Small. 2021 Sep;17(38):e2103198. doi: 10.1002/smll.202103198. Epub 2021 Aug 15. PubMed
Therapeutic Potential of the Cyclin-Dependent Kinase Inhibitor Flavopiridol on c-Myc Overexpressing Esophageal Cancer. Hassan MS, Cwidak N, Johnson C, Daster S, Eppenberger-Castori S, Awasthi N, Li J, Schwarz MA, von Holzen U. Front Pharmacol. 2021 Sep 21;12:746385. doi: 10.3389/fphar.2021.746385. eCollection 2021. PubMed
Obesity Impairs Embryonic Myogenesis by Enhancing BMP Signaling within the Dermomyotome. Zhao L, Law NC, Gomez NA, Son J, Gao Y, Liu X, de Avila JM, Zhu MJ, Du M. Adv Sci (Weinh). 2021 Nov;8(22):e2102157. doi: 10.1002/advs.202102157. Epub 2021 Oct 14. PubMed
The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer's disease. Qureshi YH, Berman DE, Marsh SE, Klein RL, Patel VM, Simoes S, Kannan S, Petsko GA, Stevens B, Small SA. Cell Rep. 2022 Jan 18;38(3):110262. doi: 10.1016/j.celrep.2021.110262. PubMed
Prediction and pan-cancer analysis of mammalian transcripts involved in target directed miRNA degradation. Simeone I, Rubolino C, Noviello TMR, Farinello D, Cerulo L, Marzi MJ, Nicassio F. Nucleic Acids Res. 2022 Feb 28;50(4):2019-2035. doi: 10.1093/nar/gkac057. PubMed
Gene Co-expression Analysis of the Human Substantia Nigra Identifies ZNHIT1 as an SNCA Co-expressed Gene that Protects Against alpha-Synuclein-Induced Impairments in Neurite Growth and Mitochondrial Dysfunction in SH-SY5Y Cells. McCarthy E, Barron A, Morales-Prieto N, Mazzocchi M, McCarthy CM, Collins LM, Sullivan AM, O'Keeffe GW. Mol Neurobiol. 2022 May;59(5):2745-2757. doi: 10.1007/s12035-022-02768-9. Epub 2022 Feb 17. PubMed
Entamoeba histolytica Develops Resistance to Complement Deposition and Lysis after Acquisition of Human Complement-Regulatory Proteins through Trogocytosis. Miller HW, Tam TSY, Ralston KS. mBio. 2022 Apr 26;13(2):e0316321. doi: 10.1128/mbio.03163-21. Epub 2022 Mar 1. PubMed
Methylation at a conserved lysine residue modulates tau assembly and cellular functions. Shams H, Matsunaga A, Ma Q, Mofrad MRK, Didonna A. Mol Cell Neurosci. 2022 May;120:103707. doi: 10.1016/j.mcn.2022.103707. Epub 2022 Feb 26. PubMed
A Modular Hepatitis E Virus Replicon System for Studies on the Role of ORF1-Encoded Polyprotein Domains. Cierniak F, Ulrich RG, Groschup MH, Eiden M. Pathogens. 2022 Mar 15;11(3). pii: pathogens11030355. doi: 10.3390/pathogens11030355. PubMed
CROP: a retromer-PROPPIN complex mediating membrane fission in the endo-lysosomal system. Courtellemont T, De Leo MG, Gopaldass N, Mayer A. EMBO J. 2022 May 16;41(10):e109646. doi: 10.15252/embj.2021109646. Epub 2022 Apr 25. PubMed
Complementary omics strategies to dissect p53 signaling networks under nutrient stress. Galhuber M, Michenthaler H, Heininger C, Reinisch I, Nossing C, Krstic J, Kupper N, Moyschewitz E, Auer M, Heitzer E, Ulz P, Birner-Gruenberger R, Liesinger L, Lenihan-Geels GN, Oster M, Spreitzer E, Zenezini Chiozzi R, Schulz TJ, Schupp M, Madl T, Heck AJR, Prokesch A. Cell Mol Life Sci. 2022 May 30;79(6):326. doi: 10.1007/s00018-022-04345-8. PubMed
Protocol for engineering and validating a synthetic mitochondrial intermembrane bridge in mammalian cells. Purohit G, Viana MP, Khalimonchuk O. STAR Protoc. 2022 Jun 14;3(3):101454. doi: 10.1016/j.xpro.2022.101454. eCollection 2022 Sep 16. PubMed
Targeting Therapeutic Resistance and Multinucleate Giant Cells in CCNE1-Amplified HR-Proficient Ovarian Cancer. Bai S, Taylor SE, Jamalruddin MA, McGonigal S, Grimley E, Yang D, Bernstein KA, Buckanovich RJ. Mol Cancer Ther. 2022 Sep 6;21(9):1473-1484. doi: 10.1158/1535-7163.MCT-21-0873. PubMed
Protocol for morphometric analysis of neurons derived from human pluripotent stem cells. Mucci S, Rodriguez-Varela MS, Isaja L, Ferriol-Laffouillere SL, Sevlever GE, Scassa ME, Romorini L. STAR Protoc. 2022 Jun 18;3(3):101487. doi: 10.1016/j.xpro.2022.101487. eCollection 2022 Sep 16. PubMed
Identification of the stress granule transcriptome via RNA-editing in single cells and in vivo. van Leeuwen W, VanInsberghe M, Battich N, Salmen F, van Oudenaarden A, Rabouille C. Cell Rep Methods. 2022 Jun 20;2(6):100235. doi: 10.1016/j.crmeth.2022.100235. eCollection 2022 Jun 20. PubMed
Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1. Feng Z, Hom ME, Bearrood TE, Rosenthal ZC, Fernandez D, Ondrus AE, Gu Y, McCormick AK, Tomaske MG, Marshall CR, Kline T, Chen CH, Mochly-Rosen D, Kuo CJ, Chen JK. Nat Chem Biol. 2022 Jul 4. pii: 10.1038/s41589-022-01048-w. doi: 10.1038/s41589-022-01048-w. PubMed
Phenotypic heterogeneity driven by plasticity of the intermediate EMT state governs disease progression and metastasis in breast cancer. Brown MS, Abdollahi B, Wilkins OM, Lu H, Chakraborty P, Ognjenovic NB, Muller KE, Jolly MK, Christensen BC, Hassanpour S, Pattabiraman DR. Sci Adv. 2022 Aug 5;8(31):eabj8002. doi: 10.1126/sciadv.abj8002. Epub 2022 Aug 3. PubMed
Relevance of Abnormal KCNN1 Expression and Osmotic Hypersensitivity in Ewing Sarcoma. Fuest S, Post C, Balbach ST, Jabar S, Neumann I, Schimmelpfennig S, Sargin S, Nass E, Budde T, Kailayangiri S, Altvater B, Ranft A, Hartmann W, Dirksen U, Rossig C, Schwab A, Petho Z. Cancers (Basel). 2022 Oct 1;14(19):4819. doi: 10.3390/cancers14194819. PubMed
TRPM8 contributes to sex dimorphism by promoting recovery of normal sensitivity in a mouse model of chronic migraine. Alarcon-Alarcon D, Cabanero D, de Andres-Lopez J, Nikolaeva-Koleva M, Giorgi S, Fernandez-Ballester G, Fernandez-Carvajal A, Ferrer-Montiel A. Nat Commun. 2022 Oct 22;13(1):6304. doi: 10.1038/s41467-022-33835-3. PubMed
Nuclear transport of STAT6 determines the matrix rigidity dependent M2 activation of macrophages. Kim JK, Han SB, Park SI, Kim IS, Kim DH. Biomaterials. 2022 Nov;290:121859. doi: 10.1016/j.biomaterials.2022.121859. Epub 2022 Oct 19. PubMed
Direct quantification of cytosolic delivery of drug nanocarriers using FlAsH-EDT2. Rotem R, Bertolini JA, Salvioni L, Barbieri L, Rizzuto MA, Tinelli V, Gori A, Adams S, Colombo M, Prosperi D. Nanomedicine. 2023 Jan;47:102626. doi: 10.1016/j.nano.2022.102626. Epub 2022 Nov 7. PubMed
Application of Lyophilized Gene-Delivery Formulations to Dental Implant Surfaces: Non-Cariogenic Lyoprotectant Preserves Transfection Activity of Polyplexes Long-Term. Malkawi WI, Laird NZ, Phruttiwanichakun P, Mohamed E, Elangovan S, Salem AK. J Pharm Sci. 2023 Jan;112(1):83-90. doi: 10.1016/j.xphs.2022.11.008. Epub 2022 Nov 11. PubMed
Suppressing gain-of-function proteins via CRISPR/Cas9 system in SCA1 cells. Pappada M, Bonuccelli O, Buratto M, Fontana R, Sicurella M, Caproni A, Fuselli S, Benazzo A, Bertorelli R, De Sanctis V, Cavallerio P, Simioni V, Tugnoli V, Salvatori F, Marconi P. Sci Rep. 2022 Nov 24;12(1):20285. doi: 10.1038/s41598-022-24299-y. PubMed
AMP-activated protein kinase inhibition in fibro-adipogenic progenitors impairs muscle regeneration and increases fibrosis. Liu X, Zhao L, Gao Y, Chen Y, Tian Q, Son JS, Chae SA, de Avila JM, Zhu MJ, Du M. J Cachexia Sarcopenia Muscle. 2023 Feb;14(1):479-492. doi: 10.1002/jcsm.13150. Epub 2022 Dec 13. PubMed
Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration. Travis AM, Manocha S, Willer JR, Wessler TS, Skiba NP, Pearring JN. Elife. 2023 Jan 4;12:e80533. doi: 10.7554/eLife.80533. PubMed
SARS-CoV-2 Uses Nonstructural Protein 16 To Evade Restriction by IFIT1 and IFIT3. Schindewolf C, Lokugamage K, Vu MN, Johnson BA, Scharton D, Plante JA, Kalveram B, Crocquet-Valdes PA, Sotcheff S, Jaworski E, Alvarado RE, Debbink K, Daugherty MD, Weaver SC, Routh AL, Walker DH, Plante KS, Menachery VD. J Virol. 2023 Feb 28;97(2):e0153222. doi: 10.1128/jvi.01532-22. Epub 2023 Feb 1. PubMed
Gene-encoding DNA origami for mammalian cell expression. Kretzmann JA, Liedl A, Monferrer A, Mykhailiuk V, Beerkens S, Dietz H. Nat Commun. 2023 Feb 23;14(1):1017. doi: 10.1038/s41467-023-36601-1. PubMed
Metallic micro-ring device for highly efficient large cargo delivery in mammalian cells using infrared light pulses. Shinde A, Shinde P, Kar S, Illath K, Dey S, Mahapatra NR, Nagai M, Santra TS. Lab Chip. 2023 May 2;23(9):2175-2192. doi: 10.1039/d2lc00899h. PubMed
HIV-1 Vpr combats the PU.1-driven antiviral response in primary human macrophages. Virgilio MC, Miguel Disbennett W, Chen T, Lubow J, Welch JD, Collins KL. bioRxiv. 2023 Mar 21:2023.03.21.533528. doi: 10.1101/2023.03.21.533528. Preprint. PubMed
ARRDC5 expression is conserved in mammalian testes and required for normal sperm morphogenesis. Giassetti MI, Miao D, Law NC, Oatley MJ, Park J, Robinson LD, Maddison LA, Bernhardt ML, Oatley JM. Nat Commun. 2023 Apr 17;14(1):2111. doi: 10.1038/s41467-023-37735-y. PubMed
B cells require licensing by dendritic cells to serve as primary antigen-presenting cells for plasmid DNA. Rastogi I, McNeel DG. Oncoimmunology. 2023 May 15;12(1):2212550. doi: 10.1080/2162402X.2023.2212550. eCollection 2023. PubMed
Suppression of myeloid YAP antagonizes adverse cardiac remodeling during pressure overload stress. Francisco J, Guan J, Zhang Y, Nakada Y, Mareedu S, Sung EA, Hu CM, Oka S, Zhai P, Sadoshima J, Del Re DP. J Mol Cell Cardiol. 2023 Aug;181:1-14. doi: 10.1016/j.yjmcc.2023.05.004. Epub 2023 May 24. PubMed
Protospacer modification improves base editing of a canonical splice site variant and recovery of CFTR function in human airway epithelial cells. Joynt AT, Kavanagh EW, Newby GA, Mitchell S, Eastman AC, Paul KC, Bowling AD, Osorio DL, Merlo CA, Patel SU, Raraigh KS, Liu DR, Sharma N, Cutting GR. Mol Ther Nucleic Acids. 2023 Jun 29;33:335-350. doi: 10.1016/j.omtn.2023.06.020. eCollection 2023 Sep 12. PubMed
Use of adenine base editing and homology-independent targeted integration strategies to correct the cystic fibrosis causing variant, W1282X. Mention K, Cavusoglu-Doran K, Joynt AT, Santos L, Sanz D, Eastman AC, Merlo C, Langfelder-Schwind E, Scallan MF, Farinha CM, Cutting GR, Sharma N, Harrison PT. Hum Mol Genet. 2023 Nov 17;32(23):3237-3248. doi: 10.1093/hmg/ddad143. PubMed
Increased intracellular diffusivity of macromolecules within a mammalian cell by low-intensity pulsed ultrasound. Kim H, Choi Y, Kim SY, Pahk KJ. Ultrason Sonochem. 2023 Nov;100:106644. doi: 10.1016/j.ultsonch.2023.106644. Epub 2023 Oct 10. PubMed
CKAP5 stabilizes CENP-E at kinetochores by regulating microtubule-chromosome attachments. Lakshmi RB, Nayak P, Raz L, Sarkar A, Saroha A, Kumari P, Nair VM, Kombarakkaran DP, Sajana S, M G S, Agasti SS, Paul R, Ben-David U, Manna TK. EMBO Rep. 2024 Apr;25(4):1909-1935. doi: 10.1038/s44319-024-00106-9. Epub 2024 Feb 29. PubMed
Mi-2beta promotes immune evasion in melanoma by activating EZH2 methylation. Li C, Wang Z, Yao L, Lin X, Jian Y, Li Y, Zhang J, Shao J, Tran PD, Hagman JR, Cao M, Cong Y, Li HY, Goding CR, Xu ZX, Liao X, Miao X, Cui R. Nat Commun. 2024 Mar 9;15(1):2163. doi: 10.1038/s41467-024-46422-5. PubMed
Chromatin profiling reveals TFAP4 as a critical transcriptional regulator of bovine satellite cell differentiation. Lyu P, Jiang H. BMC Genomics. 2024 Mar 12;25(1):272. doi: 10.1186/s12864-024-10189-2. PubMed
Unveiling a Shield of Hope: A Novel Multiepitope-Based Immunogen for Cross-Serotype Cellular Defense against Dengue Virus. Manocha N, Laubreton D, Robert X, Marvel J, Gueguen-Chaignon V, Gouet P, Kumar P, Khanna M. Vaccines (Basel). 2024 Mar 16;12(3):316. doi: 10.3390/vaccines12030316. PubMed
Human gene regulatory evolution is driven by the divergence of regulatory element function in both cis and trans. Hansen TJ, Fong SL, Day JK, Capra JA, Hodges E. Cell Genom. 2024 Apr 10;4(4):100536. doi: 10.1016/j.xgen.2024.100536. PubMed
PARP inhibitors suppress tumours via centrosome error-induced senescence independent of DNA damage response. Yue W, Li X, Zhan X, Wang L, Ma J, Bi M, Wang Q, Gu X, Xie B, Liu T, Guo H, Zhu X, Song C, Qiao J, Li M. EBioMedicine. 2024 May;103:105129. doi: 10.1016/j.ebiom.2024.105129. Epub 2024 Apr 18. PubMed
Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice. Chandia-Cristi A, Gutierrez DA, Dulcey AE, Lara M, Vargas L, Lin YH, Jimenez-Munoz P, Larenas G, Xu X, Wang A, Owens A, Dextras C, Chen Y, Pinto C, Marin T, Almarza-Salazar H, Acevedo K, Cancino GI, Hu X, Rojas P, Ferrer M, Southall N, Henderson MJ, Zanlungo S, Marugan JJ, Alvarez R A. Cell Rep. 2024 May 28;43(5):114144. doi: 10.1016/j.celrep.2024.114144. Epub 2024 Apr 23. PubMed
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Strategies for Improved pDNA Loading and Protection Using Cationic and Neutral LNPs with Industrial Scalability Potential Using Microfluidic Technology. Ottonelli I, Adani E, Bighinati A, Cuoghi S, Tosi G, Vandelli MA, Ruozi B, Marigo V, Duskey JT. Int J Nanomedicine. 2024 May 14;19:4235-4251. doi: 10.2147/IJN.S457302. eCollection 2024. PubMed
Sonic Hedgehog activates prostaglandin signaling to stabilize primary cilium length. Ansari SS, Dillard ME, Zhang Y, Austria MA, Boatwright N, Shelton EL, Stewart DP, Johnson A, Wang CE, Young BM, Rankovic Z, Hansen BS, Pruett-Miller SM, Carisey AF, Schuetz JD, Robinson CG, Ogden SK. J Cell Biol. 2024 Sep 2;223(9):e202306002. doi: 10.1083/jcb.202306002. Epub 2024 Jun 10. PubMed

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