NG-ABEmax Citations (19)
Originally described in: Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors.Huang TP, Zhao KT, Miller SM, Gaudelli NM, Oakes BL, Fellmann C, Savage DF, Liu DR Nat Biotechnol. 2019 May 20. pii: 10.1038/s41587-019-0134-y. doi: 10.1038/s41587-019-0134-y. PubMed Journal
Articles Citing NG-ABEmax
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Modeling Niemann-Pick disease type C in a human haploid cell line allows for patient variant characterization and clinical interpretation.
Erwood S, Brewer RA, Bily TMI, Maino E, Zhou L, Cohn RD, Ivakine EA.
Genome Res. 2019 Dec;29(12):2010-2019. doi: 10.1101/gr.250720.119. Epub 2019 Nov 21.
PubMed
Associated Plasmids |
| Development of a DNA double-strand break-free base editing tool in Corynebacterium glutamicum for genome editing and metabolic engineering. Deng C, Lv X, Li J, Liu Y, Du G, Liu L. Metab Eng Commun. 2020 Jun 1;11:e00135. doi: 10.1016/j.mec.2020.e00135. eCollection 2020 Dec. PubMed |
| Prime editing for functional repair in patient-derived disease models. Schene IF, Joore IP, Oka R, Mokry M, van Vugt AHM, van Boxtel R, van der Doef HPJ, van der Laan LJW, Verstegen MMA, van Hasselt PM, Nieuwenhuis EES, Fuchs SA. Nat Commun. 2020 Oct 23;11(1):5352. doi: 10.1038/s41467-020-19136-7. PubMed |
Engineered Prime Editors with PAM flexibility.
Kweon J, Yoon JK, Jang AH, Shin HR, See JE, Jang G, Kim JI, Kim Y.
Mol Ther. 2021 Feb 23. pii: S1525-0016(21)00089-7. doi: 10.1016/j.ymthe.2021.02.022.
PubMed
Associated Plasmids |
| Precise correction of Duchenne muscular dystrophy exon deletion mutations by base and prime editing. Chemello F, Chai AC, Li H, Rodriguez-Caycedo C, Sanchez-Ortiz E, Atmanli A, Mireault AA, Liu N, Bassel-Duby R, Olson EN. Sci Adv. 2021 Apr 30;7(18). pii: 7/18/eabg4910. doi: 10.1126/sciadv.abg4910. Print 2021 Apr. PubMed |
| Human cell based directed evolution of adenine base editors with improved efficiency. Fu J, Li Q, Liu X, Tu T, Lv X, Yin X, Lv J, Song Z, Qu J, Zhang J, Li J, Gu F. Nat Commun. 2021 Oct 8;12(1):5897. doi: 10.1038/s41467-021-26211-0. PubMed |
Mutation-specific reporter for optimization and enrichment of prime editing.
Schene IF, Joore IP, Baijens JHL, Stevelink R, Kok G, Shehata S, Ilcken EF, Nieuwenhuis ECM, Bolhuis DP, van Rees RCM, Spelier SA, van der Doef HPJ, Beekman JM, Houwen RHJ, Nieuwenhuis EES, Fuchs SA.
Nat Commun. 2022 Mar 1;13(1):1028. doi: 10.1038/s41467-022-28656-3.
PubMed
Associated Plasmids |
| In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration. Choi EH, Suh S, Foik AT, Leinonen H, Newby GA, Gao XD, Banskota S, Hoang T, Du SW, Dong Z, Raguram A, Kohli S, Blackshaw S, Lyon DC, Liu DR, Palczewski K. Nat Commun. 2022 Apr 5;13(1):1830. doi: 10.1038/s41467-022-29490-3. PubMed |
| Trapping of CDC42 C-terminal variants in the Golgi drives pyrin inflammasome hyperactivation. Nishitani-Isa M, Mukai K, Honda Y, Nihira H, Tanaka T, Shibata H, Kodama K, Hiejima E, Izawa K, Kawasaki Y, Osawa M, Katata Y, Onodera S, Watanabe T, Uchida T, Kure S, Takita J, Ohara O, Saito MK, Nishikomori R, Taguchi T, Sasahara Y, Yasumi T. J Exp Med. 2022 Jun 6;219(6). pii: 213184. doi: 10.1084/jem.20211889. Epub 2022 Apr 28. PubMed |
| Impaired activity of the fusogenic micropeptide Myomixer causes myopathy resembling Carey-Fineman-Ziter syndrome. Ramirez-Martinez A, Zhang Y, van den Boogaard MJ, McAnally JR, Rodriguez-Caycedo C, Chai AC, Chemello F, Massink MP, Cuppen I, Elferink MG, van Es RJ, Janssen NG, Walraven-van Oijen LP, Liu N, Bassel-Duby R, van Jaarsveld RH, Olson EN. J Clin Invest. 2022 Jun 1;132(11). pii: 159002. doi: 10.1172/JCI159002. PubMed |
| Precise genomic editing of pathogenic mutations in RBM20 rescues dilated cardiomyopathy. Nishiyama T, Zhang Y, Cui M, Li H, Sanchez-Ortiz E, McAnally JR, Tan W, Kim J, Chen K, Xu L, Bassel-Duby R, Olson EN. Sci Transl Med. 2022 Nov 23;14(672):eade1633. doi: 10.1126/scitranslmed.ade1633. Epub 2022 Nov 23. PubMed |
| Base editing correction of hypertrophic cardiomyopathy in human cardiomyocytes and humanized mice. Chai AC, Cui M, Chemello F, Li H, Chen K, Tan W, Atmanli A, McAnally JR, Zhang Y, Xu L, Liu N, Bassel-Duby R, Olson EN. Nat Med. 2023 Feb;29(2):401-411. doi: 10.1038/s41591-022-02176-5. Epub 2023 Feb 16. PubMed |
| In vivo adenine base editing corrects newborn murine model of Hurler syndrome. Su J, Jin X, She K, Liu Y, Song L, Zhao Q, Xiao J, Li R, Deng H, Lu F, Yang Y. Mol Biomed. 2023 Feb 23;4(1):6. doi: 10.1186/s43556-023-00120-8. PubMed |
| Transition Substitution of Desired Bases in Human Pluripotent Stem Cells with Base Editors: A Step-by-Step Guide. Park JC, Kim KT, Jang HK, Cha HJ. Int J Stem Cells. 2023 May 30;16(2):234-243. doi: 10.15283/ijsc22171. Epub 2023 Feb 28. PubMed |
| The Wild-Type tRNA Adenosine Deaminase Enzyme TadA Is Capable of Sequence-Specific DNA Base Editing. Ranzau BL, Rallapalli KL, Evanoff M, Paesani F, Komor AC. Chembiochem. 2023 Aug 15;24(16):e202200788. doi: 10.1002/cbic.202200788. Epub 2023 May 24. PubMed |
| Highly Efficient A-to-G Editing in PFFs via Multiple ABEs. Jing Q, Liu W, Jiang H, Liao Y, Yang Q, Xing Y. Genes (Basel). 2023 Apr 13;14(4):908. doi: 10.3390/genes14040908. PubMed |
| Targeted, programmable, and precise tandem duplication in the mammalian genome. Jiao Y, Li M, He X, Wang Y, Song J, Hu Y, Li L, Zhou L, Jiang L, Qu J, Xie L, Chen Q, Yao S. Genome Res. 2023 May;33(5):779-786. doi: 10.1101/gr.277261.122. Epub 2023 Jun 9. PubMed |
| One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids. Geurts MH, Gandhi S, Boretto MG, Akkerman N, Derks LLM, van Son G, Celotti M, Harshuk-Shabso S, Peci F, Begthel H, Hendriks D, Schurmann P, Andersson-Rolf A, Chuva de Sousa Lopes SM, van Es JH, van Boxtel R, Clevers H. Nat Commun. 2023 Aug 17;14(1):4998. doi: 10.1038/s41467-023-40701-3. PubMed |
| Use of adenine base editing and homology-independent targeted integration strategies to correct the cystic fibrosis causing variant, W1282X. Mention K, Cavusoglu-Doran K, Joynt AT, Santos L, Sanz D, Eastman AC, Merlo C, Langfelder-Schwind E, Scallan MF, Farinha CM, Cutting GR, Sharma N, Harrison PT. Hum Mol Genet. 2023 Nov 17;32(23):3237-3248. doi: 10.1093/hmg/ddad143. PubMed |
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