pWPI Citations (155)
Originally described in: Trono Lab Constitutive Lentiviral PlasmidsUnpublished
Articles Citing pWPI
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| Feeder-free culture of human embryonic stem cells in conditioned medium for efficient genetic modification. Braam SR, Denning C, Matsa E, Young LE, Passier R, Mummery CL. Nat Protoc. 2008;3(9):1435-43. doi: 10.1038/nprot.2008.140. PubMed |
| Regulation of human bone marrow stromal cell proliferation and differentiation capacity by glucocorticoid receptor and AP-1 crosstalk. Carcamo-Orive I, Gaztelumendi A, Delgado J, Tejados N, Dorronsoro A, Fernandez-Rueda J, Pennington DJ, Trigueros C. J Bone Miner Res. 2010 Oct;25(10):2115-25. doi: 10.1002/jbmr.120. PubMed |
| PKCzeta regulates cell polarisation and proliferation restriction during mammary acinus formation. Whyte J, Thornton L, McNally S, McCarthy S, Lanigan F, Gallagher WM, Stein T, Martin F. J Cell Sci. 2010 Oct 1;123(Pt 19):3316-28. doi: 10.1242/jcs.065243. PubMed |
| Anthrax lethal factor activates K(+) channels to induce IL-1beta secretion in macrophages. Thomas J, Epshtein Y, Chopra A, Ordog B, Ghassemi M, Christman JW, Nattel S, Cook JL, Levitan I. J Immunol. 2011 May 1;186(9):5236-43. doi: 10.4049/jimmunol.1001078. Epub 2011 Mar 18. PubMed |
| BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model. Raabe EH, Lim KS, Kim JM, Meeker A, Mao XG, Nikkhah G, Maciaczyk J, Kahlert U, Jain D, Bar E, Cohen KJ, Eberhart CG. Clin Cancer Res. 2011 Jun 1;17(11):3590-9. doi: 10.1158/1078-0432.CCR-10-3349. PubMed |
| Lentiviral-mediated knockdown during ex vivo erythropoiesis of human hematopoietic stem cells. Palii CG, Pasha R, Brand M. J Vis Exp. 2011 Jul 16;(53). pii: 2813. doi: 10.3791/2813. PubMed |
| Heightened expression of MICA enhances the cytotoxicity of NK cells or CD8+T cells to human corneal epithelium in vitro. Hong J, Qiu T, Qian T, Li G, Yu X, Chen J, Le Q, Sun X, Xu J. BMC Ophthalmol. 2012 Apr 4;12:6. doi: 10.1186/1471-2415-12-6. PubMed |
| Inverse fusion PCR cloning. Spiliotis M. PLoS One. 2012;7(4):e35407. doi: 10.1371/journal.pone.0035407. Epub 2012 Apr 17. PubMed |
| Quantitative assessment on the cloning efficiencies of lentiviral transfer vectors with a unique clone site. Zhang G, Tandon A. Sci Rep. 2012;2:1-8. doi: 10.1038/srep00415. Epub 2012 May 22. PubMed |
| Androgen receptor serine 81 mediates Pin1 interaction and activity. La Montagna R, Caligiuri I, Maranta P, Lucchetti C, Esposito L, Paggi MG, Toffoli G, Rizzolio F, Giordano A. Cell Cycle. 2012 Sep 15;11(18):3415-20. doi: 10.4161/cc.21730. Epub 2012 Aug 16. PubMed |
| Tissue-specific interaction of Per1/2 and Dec2 in the regulation of fibroblast circadian rhythms. Tsang AH, Sanchez-Moreno C, Bode B, Rossner MJ, Garaulet M, Oster H. J Biol Rhythms. 2012 Dec;27(6):478-89. doi: 10.1177/0748730412462838. PubMed |
| Bovine herpesvirus 4 glycoprotein B is indispensable for lytic replication and irreplaceable by VSVg. Franceschi V, Capocefalo A, Cavirani S, Donofrio G. BMC Vet Res. 2013 Jan 9;9:6. doi: 10.1186/1746-6148-9-6. PubMed |
| Analysis of the cytoprotective role of alpha-crystallins in cell survival and implication of the alphaA-crystallin C-terminal extension domain in preventing Bax-induced apoptosis. Hamann S, Metrailler S, Schorderet DF, Cottet S. PLoS One. 2013;8(2):e55372. doi: 10.1371/journal.pone.0055372. Epub 2013 Feb 1. PubMed |
| PROX1 promotes hepatocellular carcinoma metastasis by way of up-regulating hypoxia-inducible factor 1alpha expression and protein stability. Liu Y, Zhang JB, Qin Y, Wang W, Wei L, Teng Y, Guo L, Zhang B, Lin Z, Liu J, Ren ZG, Ye QH, Xie Y. Hepatology. 2013 Aug;58(2):692-705. doi: 10.1002/hep.26398. PubMed |
| Macrohistone variants preserve cell identity by preventing the gain of H3K4me2 during reprogramming to pluripotency. Barrero MJ, Sese B, Kuebler B, Bilic J, Boue S, Marti M, Izpisua Belmonte JC. Cell Rep. 2013 Apr 25;3(4):1005-11. doi: 10.1016/j.celrep.2013.02.029. Epub 2013 Mar 28. PubMed |
| Prox1 directly interacts with LSD1 and recruits the LSD1/NuRD complex to epigenetically co-repress CYP7A1 transcription. Ouyang H, Qin Y, Liu Y, Xie Y, Liu J. PLoS One. 2013 Apr 23;8(4):e62192. doi: 10.1371/journal.pone.0062192. Print 2013. PubMed |
| Efficient heterologous antigen gene delivery and expression by a replication-attenuated BoHV-4-based vaccine vector. Capocefalo A, Mangia C, Franceschi V, Jacca S, van Santen VL, Donofrio G. Vaccine. 2013 Aug 20;31(37):3906-14. doi: 10.1016/j.vaccine.2013.06.052. Epub 2013 Jul 3. PubMed |
| LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program. Mao XG, Hutt-Cabezas M, Orr BA, Weingart M, Taylor I, Rajan AK, Odia Y, Kahlert U, Maciaczyk J, Nikkhah G, Eberhart CG, Raabe EH. Oncotarget. 2013 Jul;4(7):1050-64. PubMed |
| Neuropathic and inflammatory pain are modulated by tuberoinfundibular peptide of 39 residues. Dimitrov EL, Kuo J, Kohno K, Usdin TB. Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):13156-61. doi: 10.1073/pnas.1306342110. Epub 2013 Jul 22. PubMed |
| The Coxsackievirus and Adenovirus Receptor (CAR) undergoes ectodomain shedding and regulated intramembrane proteolysis (RIP). Houri N, Huang KC, Nalbantoglu J. PLoS One. 2013 Aug 28;8(8):e73296. doi: 10.1371/journal.pone.0073296. eCollection 2013. PubMed |
| Improved lentiviral transduction of ALS motoneurons in vivo via dual targeting. O'Leary VB, Ovsepian SV, Bodeker M, Dolly JO. Mol Pharm. 2013 Nov 4;10(11):4195-206. doi: 10.1021/mp400247t. Epub 2013 Oct 11. PubMed |
| Thalamic neuropeptide mediating the effects of nursing on lactation and maternal motivation. Cservenak M, Szabo ER, Bodnar I, Leko A, Palkovits M, Nagy GM, Usdin TB, Dobolyi A. Psychoneuroendocrinology. 2013 Dec;38(12):3070-84. doi: 10.1016/j.psyneuen.2013.09.004. Epub 2013 Sep 14. PubMed |
| HIV-1 infection is blocked at an early stage in cells devoid of mitochondrial DNA. Lu G, Matsuura SE, Barrientos A, Scott WA. PLoS One. 2013 Oct 21;8(10):e78035. doi: 10.1371/journal.pone.0078035. eCollection 2013. PubMed |
| Bone environment is essential for osteosarcoma development from transformed mesenchymal stem cells. Rubio R, Abarrategi A, Garcia-Castro J, Martinez-Cruzado L, Suarez C, Tornin J, Santos L, Astudillo A, Colmenero I, Mulero F, Rosu-Myles M, Menendez P, Rodriguez R. Stem Cells. 2014 May;32(5):1136-48. doi: 10.1002/stem.1647. PubMed |
| SAA1 polymorphisms are associated with variation in antiangiogenic and tumor-suppressive activities in nasopharyngeal carcinoma. Lung HL, Man OY, Yeung MC, Ko JM, Cheung AK, Law EW, Yu Z, Shuen WH, Tung E, Chan SH, Bangarusamy DK, Cheng Y, Yang X, Kan R, Phoon Y, Chan KC, Chua D, Kwong DL, Lee AW, Ji MF, Lung ML. Oncogene. 2015 Feb 12;34(7):878-89. doi: 10.1038/onc.2014.12. Epub 2014 Mar 10. PubMed |
| MST4 promotes hepatocellular carcinoma epithelial-mesenchymal transition and metastasis via activation of the p-ERK pathway. Lin ZH, Wang L, Zhang JB, Liu Y, Li XQ, Guo L, Zhang B, Zhu WW, Ye QH. Int J Oncol. 2014 Aug;45(2):629-40. doi: 10.3892/ijo.2014.2455. Epub 2014 May 22. PubMed |
| Nrf2, a regulator of the proteasome, controls self-renewal and pluripotency in human embryonic stem cells. Jang J, Wang Y, Kim HS, Lalli MA, Kosik KS. Stem Cells. 2014 Oct;32(10):2616-25. doi: 10.1002/stem.1764. PubMed |
| An essential role for the K+-dependent Na+/Ca2+-exchanger, NCKX4, in melanocortin-4-receptor-dependent satiety. Li XF, Lytton J. J Biol Chem. 2014 Sep 12;289(37):25445-59. doi: 10.1074/jbc.M114.564450. Epub 2014 Aug 5. PubMed |
| Interleukin-like epithelial-to-mesenchymal transition inducer activity is controlled by proteolytic processing and plasminogen-urokinase plasminogen activator receptor system-regulated secretion during breast cancer progression. Csiszar A, Kutay B, Wirth S, Schmidt U, Macho-Maschler S, Schreiber M, Alacakaptan M, Vogel GF, Aumayr K, Huber LA, Beug H. Breast Cancer Res. 2014 Sep 9;16(5):433. doi: 10.1186/s13058-014-0433-7. PubMed |
| Anti-angiogenic pathway associations of the 3p21.3 mapped BLU gene in nasopharyngeal carcinoma. Cheng Y, Ho RL, Chan KC, Kan R, Tung E, Lung HL, Yau WL, Cheung AK, Ko JM, Zhang ZF, Luo DZ, Feng ZB, Chen S, Guan XY, Kwong D, Stanbridge EJ, Lung ML. Oncogene. 2014 Oct 27. doi: 10.1038/onc.2014.353. PubMed |
| Robo4 vaccines induce antibodies that retard tumor growth. Zhuang X, Ahmed F, Zhang Y, Ferguson HJ, Steele JC, Steven NM, Nagy Z, Heath VL, Toellner KM, Bicknell R. Angiogenesis. 2015 Jan;18(1):83-95. doi: 10.1007/s10456-014-9448-z. Epub 2014 Oct 28. PubMed |
| Creatine inhibits adipogenesis by downregulating insulin-induced activation of the phosphatidylinositol 3-kinase signaling pathway. Lee N, Kim I, Park S, Han D, Ha S, Kwon M, Kim J, Byun SH, Oh W, Jeon HB, Kweon DH, Cho JY, Yoon K. Stem Cells Dev. 2015 Apr 15;24(8):983-94. doi: 10.1089/scd.2014.0130. Epub 2014 Dec 31. PubMed |
| UBE3C promotes growth and metastasis of renal cell carcinoma via activating Wnt/beta-catenin pathway. Wen JL, Wen XF, Li RB, Jin YC, Wang XL, Zhou L, Chen HX. PLoS One. 2015 Feb 6;10(2):e0115622. doi: 10.1371/journal.pone.0115622. eCollection 2015. PubMed |
| PROX1 promotes hepatocellular carcinoma proliferation and sorafenib resistance by enhancing beta-catenin expression and nuclear translocation. Liu Y, Ye X, Zhang JB, Ouyang H, Shen Z, Wu Y, Wang W, Wu J, Tao S, Yang X, Qiao K, Zhang J, Liu J, Fu Q, Xie Y. Oncogene. 2015 Feb 16. doi: 10.1038/onc.2015.7. PubMed |
| Human Bone Marrow Stromal Cells Differentiate Into Corneal Tissue and Prevent Ocular Graft-Versus-Host Disease in Mice. Sanchez-Abarca LI, Hernandez-Galilea E, Lorenzo R, Herrero C, Velasco A, Carrancio S, Caballero-Velazquez T, Rodriguez-Barbosa JI, Parrilla M, Del Canizo C, San Miguel J, Aijon J, Perez-Simon JA. Cell Transplant. 2015;24(12):2423-33. doi: 10.3727/096368915X687480. Epub 2015 Feb 18. PubMed |
Novel lentiviral-inducible transgene expression systems and versatile single-plasmid reporters for in vitro and in vivo cancer biology studies.
Shuen WH, Kan R, Yu Z, Lung HL, Lung ML.
Cancer Gene Ther. 2015 Feb 27. doi: 10.1038/cgt.2015.9.
PubMed
Associated Plasmids |
| A novel role for an RCAN3-derived peptide as a tumor suppressor in breast cancer. Martinez-Hoyer S, Sole-Sanchez S, Aguado F, Martinez-Martinez S, Serrano-Candelas E, Hernandez JL, Iglesias M, Redondo JM, Casanovas O, Messeguer R, Perez-Riba M. Carcinogenesis. 2015 Jul;36(7):792-9. doi: 10.1093/carcin/bgv056. Epub 2015 Apr 26. PubMed |
| NF-kappaB p65 Subunit Is Modulated by Latent Transforming Growth Factor-beta Binding Protein 2 (LTBP2) in Nasopharyngeal Carcinoma HONE1 and HK1 Cells. Kan R, Shuen WH, Lung HL, Cheung AK, Dai W, Kwong DL, Ng WT, Lee AW, Yau CC, Ngan RK, Tung SY, Lung ML. PLoS One. 2015 May 14;10(5):e0127239. doi: 10.1371/journal.pone.0127239. eCollection 2015. PubMed |
| Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development. Yang H, Fang L, Zhan R, Hegarty JM, Ren J, Hsiai TK, Gleeson JG, Miller YI, Trejo J, Chi NC. Dev Biol. 2015 Aug 15;404(2):49-60. doi: 10.1016/j.ydbio.2015.05.011. Epub 2015 May 22. PubMed |
| Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap. Nurnberg ST, Cheng K, Raiesdana A, Kundu R, Miller CL, Kim JB, Arora K, Carcamo-Oribe I, Xiong Y, Tellakula N, Nanda V, Murthy N, Boisvert WA, Hedin U, Perisic L, Aldi S, Maegdefessel L, Pjanic M, Owens GK, Tallquist MD, Quertermous T. PLoS Genet. 2015 May 28;11(5):e1005155. doi: 10.1371/journal.pgen.1005155. eCollection 2015 May. PubMed |
| Lhx8 mediated Wnt and TGFbeta pathways in tooth development and regeneration. Zhou C, Yang G, Chen M, Wang C, He L, Xiang L, Chen D, Ling J, Mao JJ. Biomaterials. 2015 Sep;63:35-46. doi: 10.1016/j.biomaterials.2015.06.004. Epub 2015 Jun 3. PubMed |
| BoHV-4-Based Vector Single Heterologous Antigen Delivery Protects STAT1(-/-) Mice from Monkeypoxvirus Lethal Challenge. Franceschi V, Parker S, Jacca S, Crump RW, Doronin K, Hembrador E, Pompilio D, Tebaldi G, Estep RD, Wong SW, Buller MR, Donofrio G. PLoS Negl Trop Dis. 2015 Jun 18;9(6):e0003850. doi: 10.1371/journal.pntd.0003850. eCollection 2015 Jun. PubMed |
| Generation of induced pluripotent stem cells from domestic goats. Sandmaier SE, Nandal A, Powell A, Garrett W, Blomberg L, Donovan DM, Talbot N, Telugu BP. Mol Reprod Dev. 2015 Jun 26. doi: 10.1002/mrd.22512. PubMed |
| Trib3 Is Elevated in Parkinson's Disease and Mediates Death in Parkinson's Disease Models. Aime P, Sun X, Zareen N, Rao A, Berman Z, Volpicelli-Daley L, Bernd P, Crary JF, Levy OA, Greene LA. J Neurosci. 2015 Jul 29;35(30):10731-49. doi: 10.1523/JNEUROSCI.0614-15.2015. PubMed |
| Atypical protein kinase C induces cell transformation by disrupting Hippo/Yap signaling. Archibald A, Al-Masri M, Liew-Spilger A, McCaffrey L. Mol Biol Cell. 2015 Oct 15;26(20):3578-95. doi: 10.1091/mbc.E15-05-0265. Epub 2015 Aug 12. PubMed |
| Nuclear Localization of DNAJB6 Is Associated With Survival of Patients With Esophageal Cancer and Reduces AKT Signaling and Proliferation of Cancer Cells. Yu VZ, Wong VC, Dai W, Ko JM, Lam AK, Chan KW, Samant RS, Lung HL, Shuen WH, Law S, Chan YP, Lee NP, Tong DK, Law TT, Lee VH, Lung ML. Gastroenterology. 2015 Dec;149(7):1825-1836.e5. doi: 10.1053/j.gastro.2015.08.025. Epub 2015 Aug 22. PubMed |
| Divergent Roles of PAX2 in the Etiology and Progression of Ovarian Cancer. Al-Hujaily EM, Tang Y, Yao DS, Carmona E, Garson K, Vanderhyden BC. Cancer Prev Res (Phila). 2015 Dec;8(12):1163-73. doi: 10.1158/1940-6207.CAPR-15-0121-T. Epub 2015 Sep 15. PubMed |
| CCL18 from tumor-cells promotes epithelial ovarian cancer metastasis via mTOR signaling pathway. Wang Q, Tang Y, Yu H, Yin Q, Li M, Shi L, Zhang W, Li D, Li L. Mol Carcinog. 2015 Oct 12. doi: 10.1002/mc.22419. PubMed |
| A Common CCK-B Receptor Intronic Variant in Pancreatic Adenocarcinoma in a Hungarian Cohort. Balazs A, Nemeth BC, Ordog B, Hegyi E, Hritz I, Czako L, Czimmer J, Godi S, Csiszko A, Rakonczay Z Jr, Parniczky A, Izbeki F, Halasz A, Kahan Z, Hegyi P, Sahin-Toth M. Pancreas. 2016 Apr;45(4):541-5. doi: 10.1097/MPA.0000000000000539. PubMed |
| TRIM19/PML Restricts HIV Infection in a Cell Type-Dependent Manner. Kahle T, Volkmann B, Eissmann K, Herrmann A, Schmitt S, Wittmann S, Merkel L, Reuter N, Stamminger T, Gramberg T. Viruses. 2015 Dec 23;8(1). pii: E2. doi: 10.3390/v8010002. PubMed |
| SETD7 Regulates the Differentiation of Human Embryonic Stem Cells. Castano J, Morera C, Sese B, Boue S, Bonet-Costa C, Marti M, Roque A, Jordan A, Barrero MJ. PLoS One. 2016 Feb 18;11(2):e0149502. doi: 10.1371/journal.pone.0149502. eCollection 2016. PubMed |
| DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets. Hanaford AR, Archer TC, Price A, Kahlert UD, Maciaczyk J, Nikkhah G, Kim JW, Ehrenberger T, Clemons PA, Dancik V, Seashore-Ludlow B, Viswanathan V, Stewart ML, Rees MG, Shamji A, Schreiber S, Fraenkel E, Pomeroy SL, Mesirov JP, Tamayo P, Eberhart CG, Raabe EH. Clin Cancer Res. 2016 Mar 24. PubMed |
| SIRT1 is a critical regulator of K562 cell growth, survival, and differentiation. Duncan MT, DeLuca TA, Kuo HY, Yi M, Mrksich M, Miller WM. Exp Cell Res. 2016 May 15;344(1):40-52. doi: 10.1016/j.yexcr.2016.04.010. Epub 2016 Apr 13. PubMed |
| CXCR4 Overexpression in Human Adipose Tissue-Derived Stem Cells Improves Homing and Engraftment in an Animal Limb Ischemia Model. Kim M, Kim DI, Kim EK, Kim CW. Cell Transplant. 2017 Feb 16;26(2):191-204. doi: 10.3727/096368916X692708. Epub 2016 Aug 5. PubMed |
| MEK and TAK1 Regulate Apoptosis in Colon Cancer Cells with KRAS-Dependent Activation of Proinflammatory Signaling. McNew KL, Whipple WJ, Mehta AK, Grant TJ, Ray L, Kenny C, Singh A. Mol Cancer Res. 2016 Dec;14(12):1204-1216. Epub 2016 Sep 21. PubMed |
| Curcumin increases exosomal TCF21 thus suppressing exosome-induced lung cancer. Wu H, Zhou J, Zeng C, Wu D, Mu Z, Chen B, Xie Y, Ye Y, Liu J. Oncotarget. 2016 Dec 27;7(52):87081-87090. doi: 10.18632/oncotarget.13499. PubMed |
| IL-38 overexpression induces anti-inflammatory effects in mice arthritis models and in human macrophages in vitro. Boutet MA, Najm A, Bart G, Brion R, Touchais S, Trichet V, Layrolle P, Gabay C, Palmer G, Blanchard F, Le Goff B. Ann Rheum Dis. 2017 Jul;76(7):1304-1312. doi: 10.1136/annrheumdis-2016-210630. Epub 2017 Mar 13. PubMed |
| Sedentary lifestyle related exosomal release of Hotair from gluteal-femoral fat promotes intestinal cell proliferation. Lu X, Bai D, Liu X, Zhou C, Yang G. Sci Rep. 2017 Mar 31;7:45648. doi: 10.1038/srep45648. PubMed |
| TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells. Kim JB, Pjanic M, Nguyen T, Miller CL, Iyer D, Liu B, Wang T, Sazonova O, Carcamo-Orive I, Matic LP, Maegdefessel L, Hedin U, Quertermous T. PLoS Genet. 2017 May 8;13(5):e1006750. doi: 10.1371/journal.pgen.1006750. eCollection 2017 May. PubMed |
| Mesenchymal Stem Cell Migration and Proliferation Are Mediated by Hypoxia-Inducible Factor-1alpha Upstream of Notch and SUMO Pathways. Ciria M, Garcia NA, Ontoria-Oviedo I, Gonzalez-King H, Carrero R, De La Pompa JL, Montero JA, Sepulveda P. Stem Cells Dev. 2017 Jul 1;26(13):973-985. doi: 10.1089/scd.2016.0331. Epub 2017 May 18. PubMed |
| Prospero-related homeobox 1 drives angiogenesis of hepatocellular carcinoma through selectively activating interleukin-8 expression. Liu Y, Zhang Y, Wang S, Dong QZ, Shen Z, Wang W, Tao S, Gu C, Liu J, Xie Y, Qin LX. Hepatology. 2017 Dec;66(6):1894-1909. doi: 10.1002/hep.29337. PubMed |
| Absolute measurement of gene transcripts with Selfie-digital PCR. Podlesniy P, Trullas R. Sci Rep. 2017 Aug 21;7(1):8328. doi: 10.1038/s41598-017-08270-w. PubMed |
| ER stress and distinct outputs of the IRE1alpha RNase control proliferation and senescence in response to oncogenic Ras. Blazanin N, Son J, Craig-Lucas AB, John CL, Breech KJ, Podolsky MA, Glick AB. Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):9900-9905. doi: 10.1073/pnas.1701757114. Epub 2017 Aug 28. PubMed |
| A systematic analysis of orphan cyclins reveals CNTD2 as a new oncogenic driver in lung cancer. Gasa L, Sanchez-Botet A, Quandt E, Hernandez-Ortega S, Jimenez J, Carrasco-Garcia MA, Simonetti S, Kron SJ, Ribeiro MP, Nadal E, Villanueva A, Clotet J. Sci Rep. 2017 Aug 31;7(1):10228. doi: 10.1038/s41598-017-10770-8. PubMed |
| Regulation of autophagy, NF-kappaB signaling, and cell viability by miR-124 in KRAS mutant mesenchymal-like NSCLC cells. Mehta AK, Hua K, Whipple W, Nguyen MT, Liu CT, Haybaeck J, Weidhaas J, Settleman J, Singh A. Sci Signal. 2017 Sep 12;10(496). pii: 10/496/eaam6291. doi: 10.1126/scisignal.aam6291. PubMed |
| Promoter methylation of TCF21 may repress autophagy in the progression of lung cancer. Chen B, Zeng C, Ye Y, Wu D, Mu Z, Liu J, Xie Y, Wu H. J Cell Commun Signal. 2018 Jun;12(2):423-432. doi: 10.1007/s12079-017-0418-2. Epub 2017 Oct 30. PubMed |
| Dosing time dependent in vitro pharmacodynamics of Everolimus despite a defective circadian clock. Zhang Y, Giacchetti S, Parouchev A, Hadadi E, Li X, Dallmann R, Xandri-Monje H, Portier L, Adam R, Levi F, Dulong S, Chang Y. Cell Cycle. 2018;17(1):33-42. doi: 10.1080/15384101.2017.1387695. Epub 2018 Jan 2. PubMed |
| PAX2 maintains the differentiation of mouse oviductal epithelium and inhibits the transition to a stem cell-like state. Alwosaibai K, Abedini A, Al-Hujaily EM, Tang Y, Garson K, Collins O, Vanderhyden BC. Oncotarget. 2017 Aug 10;8(44):76881-76897. doi: 10.18632/oncotarget.20173. eCollection 2017 Sep 29. PubMed |
| H3K27me3 dynamics dictate evolving uterine states in pregnancy and parturition. Nancy P, Siewiera J, Rizzuto G, Tagliani E, Osokine I, Manandhar P, Dolgalev I, Clementi C, Tsirigos A, Erlebacher A. J Clin Invest. 2018 Jan 2;128(1):233-247. doi: 10.1172/JCI95937. Epub 2017 Nov 27. PubMed |
| A population of innate myelolymphoblastoid effector cell expanded by inactivation of mTOR complex 1 in mice. Tang F, Zhang P, Ye P, Lazarski CA, Wu Q, Bergin IL, Bender TP, Hall MN, Cui Y, Zhang L, Jiang T, Liu Y, Zheng P. Elife. 2017 Dec 5;6. pii: 32497. doi: 10.7554/eLife.32497. PubMed |
| Lysyl oxidase-like 3 is required for melanoma cell survival by maintaining genomic stability. Santamaria PG, Floristan A, Fontanals-Cirera B, Vazquez-Naharro A, Santos V, Morales S, Yuste L, Peinado H, Garcia-Gomez A, Portillo F, Hernando E, Cano A. Cell Death Differ. 2017 Dec 11. pii: 10.1038/s41418-017-0030-2. doi: 10.1038/s41418-017-0030-2. PubMed |
| Combined venetoclax and alvocidib in acute myeloid leukemia. Bogenberger J, Whatcott C, Hansen N, Delman D, Shi CX, Kim W, Haws H, Soh K, Lee YS, Peterson P, Siddiqui-Jain A, Weitman S, Stewart K, Bearss D, Mesa R, Warner S, Tibes R. Oncotarget. 2017 Nov 3;8(63):107206-107222. doi: 10.18632/oncotarget.22284. eCollection 2017 Dec 5. PubMed |
| Picornavirus 2A protease regulates stress granule formation to facilitate viral translation. Yang X, Hu Z, Fan S, Zhang Q, Zhong Y, Guo D, Qin Y, Chen M. PLoS Pathog. 2018 Feb 7;14(2):e1006901. doi: 10.1371/journal.ppat.1006901. eCollection 2018 Feb. PubMed |
| Multicellular detachment generates metastatic spheroids during intra-abdominal dissemination in epithelial ovarian cancer. Al Habyan S, Kalos C, Szymborski J, McCaffrey L. Oncogene. 2018 Sep;37(37):5127-5135. doi: 10.1038/s41388-018-0317-x. Epub 2018 May 23. PubMed |
| Context-dependent expression of a conditionally-inducible form of active Akt. Park S, Burke RE, Kareva T, Kholodilov N, Aime P, Franke TF, Levy O, Greene LA. PLoS One. 2018 Jun 19;13(6):e0197899. doi: 10.1371/journal.pone.0197899. eCollection 2018. PubMed |
| GREB1 is an estrogen receptor-regulated tumour promoter that is frequently expressed in ovarian cancer. Hodgkinson K, Forrest LA, Vuong N, Garson K, Djordjevic B, Vanderhyden BC. Oncogene. 2018 Nov;37(44):5873-5886. doi: 10.1038/s41388-018-0377-y. Epub 2018 Jul 4. PubMed |
Histidine catabolism is a major determinant of methotrexate sensitivity.
Kanarek N, Keys HR, Cantor JR, Lewis CA, Chan SH, Kunchok T, Abu-Remaileh M, Freinkman E, Schweitzer LD, Sabatini DM.
Nature. 2018 Jul 11. pii: 10.1038/s41586-018-0316-7. doi: 10.1038/s41586-018-0316-7.
PubMed
Associated Plasmids |
| A naked mole rat iPSC line expressing drug-inducible mouse pluripotency factors developed from embryonic fibroblasts. Lee SG, Mikhalchenko AE, Yim SH, Gladyshev VN. Stem Cell Res. 2018 Aug;31:197-200. doi: 10.1016/j.scr.2018.06.010. Epub 2018 Jun 20. PubMed |
| c-Fos induces chondrogenic tumor formation in immortalized human mesenchymal progenitor cells. Abarrategi A, Gambera S, Alfranca A, Rodriguez-Milla MA, Perez-Tavarez R, Rouault-Pierre K, Waclawiczek A, Chakravarty P, Mulero F, Trigueros C, Navarro S, Bonnet D, Garcia-Castro J. Sci Rep. 2018 Oct 23;8(1):15615. doi: 10.1038/s41598-018-33689-0. PubMed |
| Tetratricopeptide repeat domain 7A is a nuclear factor that modulates transcription and chromatin structure. El-Daher MT, Cagnard N, Gil M, Da Cruz MC, Leveau C, Sepulveda F, Zarhrate M, Tores F, Legoix P, Baulande S, de Villartay JP, Almouzni G, Quivy JP, Fischer A, de Saint Basile G. Cell Discov. 2018 Nov 13;4:61. doi: 10.1038/s41421-018-0061-y. eCollection 2018. PubMed |
| Cis interaction between sialylated FcgammaRIIA and the alphaI-domain of Mac-1 limits antibody-mediated neutrophil recruitment. Saggu G, Okubo K, Chen Y, Vattepu R, Tsuboi N, Rosetti F, Cullere X, Washburn N, Tahir S, Rosado AM, Holland SM, Anthony RM, Sen M, Zhu C, Mayadas TN. Nat Commun. 2018 Nov 29;9(1):5058. doi: 10.1038/s41467-018-07506-1. PubMed |
| Tyrosine phosphorylation directs TACE into extracellular vesicles via unconventional secretion. Zhao Z, Kesti T, Ugurlu H, Baur AS, Fagerlund R, Saksela K. Traffic. 2019 Mar;20(3):202-212. doi: 10.1111/tra.12630. Epub 2019 Jan 21. PubMed |
| SOX9 is a dose-dependent metastatic fate determinant in melanoma. Yang X, Liang R, Liu C, Liu JA, Cheung MPL, Liu X, Man OY, Guan XY, Lung HL, Cheung M. J Exp Clin Cancer Res. 2019 Jan 14;38(1):17. doi: 10.1186/s13046-018-0998-6. PubMed |
| p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value. Santoro A, Vlachou T, Luzi L, Melloni G, Mazzarella L, D'Elia E, Aobuli X, Pasi CE, Reavie L, Bonetti P, Punzi S, Casoli L, Sabo A, Moroni MC, Dellino GI, Amati B, Nicassio F, Lanfrancone L, Pelicci PG. Cell Rep. 2019 Jan 15;26(3):624-638.e8. doi: 10.1016/j.celrep.2018.12.071. PubMed |
| Expression of human ficolin-2 in hepatocytes confers resistance to infection by diverse hepatotropic viruses. Jalal PJ, Urbanowicz RA, Horncastle E, Pathak M, Goddard C, Saeed A, Mason CP, Ball JK, Irving WL, McClure CP, King BJ, Tarr AW. J Med Microbiol. 2019 Apr;68(4):642-648. doi: 10.1099/jmm.0.000935. Epub 2019 Feb 12. PubMed |
| Branched poly (trimethylphosphonium ethylacrylate-co-PEGA) by RAFT: alternative to cationic polyammoniums for nucleic acid complexation. Cook AB, Peltier R, Barlow TR, Tanaka J, Burns JA, Perrier S. J Interdiscip Nanomed. 2018 Dec 21;3(4):164-174. doi: 10.1002/jin2.50. eCollection 2018 Dec. PubMed |
| Construction and validation of the CRISPR/dCas9-EZH2 system for targeted H3K27Me3 modification. Chen X, Wei M, Liu X, Song S, Wang L, Yang X, Song Y. Biochem Biophys Res Commun. 2019 Apr 2;511(2):246-252. doi: 10.1016/j.bbrc.2019.02.011. Epub 2019 Feb 20. PubMed |
| Cut-and-Run: A Distinct Mechanism by which V(D)J Recombination Causes Genome Instability. Kirkham CM, Scott JNF, Wang X, Smith AL, Kupinski AP, Ford AM, Westhead DR, Stockley PG, Tuma R, Boyes J. Mol Cell. 2019 May 2;74(3):584-597.e9. doi: 10.1016/j.molcel.2019.02.025. Epub 2019 Mar 21. PubMed |
| Combined Transcriptome and Proteome Analysis of Immortalized Human Keratinocytes Expressing Human Papillomavirus 16 (HPV16) Oncogenes Reveals Novel Key Factors and Networks in HPV-Induced Carcinogenesis. Yang R, Klimentova J, Gockel-Krzikalla E, Ly R, Gmelin N, Hotz-Wagenblatt A, Rehulkova H, Stulik J, Rosl F, Niebler M. mSphere. 2019 Mar 27;4(2). pii: 4/2/e00129-19. doi: 10.1128/mSphere.00129-19. PubMed |
| Epigenetic and therapeutic implications of dnmt3b in temporomandibular joint osteoarthritis. Zhou Y, Chen M, O'Keefe RJ, Shen J, Li Z, Zhou J, Zhou X, Mao JJ. Am J Transl Res. 2019 Mar 15;11(3):1736-1747. eCollection 2019. PubMed |
| Crumbs3 is a critical factor that regulates invasion and metastasis of colon adenocarcinoma via the specific interaction with FGFR1. Iioka H, Saito K, Sakaguchi M, Tachibana T, Homma K, Kondo E. Int J Cancer. 2019 Apr 13. doi: 10.1002/ijc.32336. PubMed |
| Detection of ADP-Ribosylation of the Androgen Receptor Using the Recombinant Macrodomain AF1521 from Archaeoglobus fulgidus. Kamata T, Yang CS, Jividen K, Spencer A, Dworak N, Oostdyk LT, Paschal BM. Methods Mol Biol. 2019;1966:107-124. doi: 10.1007/978-1-4939-9195-2_9. PubMed |
| A glucose-dependent spatial patterning of exocytosis in human beta-cells is disrupted in type 2 diabetes. Fu J, Githaka JM, Dai X, Plummer G, Suzuki K, Spigelman AF, Bautista A, Kim R, Greitzer-Antes D, Fox JEM, Gaisano HY, MacDonald PE. JCI Insight. 2019 May 14;5. pii: 127896. doi: 10.1172/jci.insight.127896. PubMed |
| Parenchymal and stromal tissue regeneration of tooth organ by pivotal signals reinstated in decellularized matrix. He L, Zhou J, Chen M, Lin CS, Kim SG, Zhou Y, Xiang L, Xie M, Bai H, Yao H, Shi C, Coelho PG, Bromage TG, Hu B, Tovar N, Witek L, Wu J, Chen K, Gu W, Zheng J, Sheu TJ, Zhong J, Wen J, Niu Y, Cheng B, Gong Q, Owens DM, Stanislauskas M, Pei J, Chotkowski G, Wang S, Yang G, Zegarelli DJ, Shi X, Finkel M, Zhang W, Li J, Cheng J, Tarnow DP, Zhou X, Wang Z, Jiang X, Romanov A, Rowe DW, Wang S, Ye L, Ling J, Mao J. Nat Mater. 2019 Jun;18(6):627-637. doi: 10.1038/s41563-019-0368-6. Epub 2019 May 21. PubMed |
| KMT5A promotes metastasis of clear cell renal cell carcinoma through reducing cadherin-1 expression. Lin ZZ, Ming DS, Chen YB, Zhang JM, Chen HH, Jiang JJ, Zhang ZS. Oncol Lett. 2019 Jun;17(6):4907-4913. doi: 10.3892/ol.2019.10163. Epub 2019 Mar 19. PubMed |
| MHC-I peptide binding activity assessed by exchange after cleavage of peptide covalently linked to beta2-microglobulin. Jurewicz MM, Willis RA, Altman JD, Stern LJ. Anal Biochem. 2019 Jun 12. pii: S0003-2697(19)30180-0. doi: 10.1016/j.ab.2019.05.017. PubMed |
| miR-330-3p suppresses liver cancer cell migration by targeting MAP2K1. Jin Z, Jia B, Tan L, Liu Y. Oncol Lett. 2019 Jul;18(1):314-320. doi: 10.3892/ol.2019.10280. Epub 2019 Apr 24. PubMed |
| Unbiased Metabolic Profiling Predicts Sensitivity of High MYC-Expressing Atypical Teratoid/Rhabdoid Tumors to Glutamine Inhibition with 6-Diazo-5-Oxo-L-Norleucine. Wang SZ, Poore B, Alt J, Price A, Allen SJ, Hanaford AR, Kaur H, Orr BA, Slusher BS, Eberhart CG, Raabe EH, Rubens JA. Clin Cancer Res. 2019 Oct 1;25(19):5925-5936. doi: 10.1158/1078-0432.CCR-19-0189. Epub 2019 Jul 12. PubMed |
| Orally bioavailable glutamine antagonist prodrug JHU-083 penetrates mouse brain and suppresses the growth of MYC-driven medulloblastoma. Hanaford AR, Alt J, Rais R, Wang SZ, Kaur H, Thorek DLJ, Eberhart CG, Slusher BS, Martin AM, Raabe EH. Transl Oncol. 2019 Oct;12(10):1314-1322. doi: 10.1016/j.tranon.2019.05.013. Epub 2019 Jul 21. PubMed |
| COX2 is induced in the ovarian epithelium during ovulatory wound repair and promotes cell survivaldagger. Carter LE, Cook DP, Collins O, Gamwell LF, Dempster HA, Wong HW, McCloskey CW, Garson K, Vuong NH, Vanderhyden BC. Biol Reprod. 2019 Nov 21;101(5):961-974. doi: 10.1093/biolre/ioz134. PubMed |
| Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis. Wirka RC, Wagh D, Paik DT, Pjanic M, Nguyen T, Miller CL, Kundu R, Nagao M, Coller J, Koyano TK, Fong R, Woo YJ, Liu B, Montgomery SB, Wu JC, Zhu K, Chang R, Alamprese M, Tallquist MD, Kim JB, Quertermous T. Nat Med. 2019 Aug;25(8):1280-1289. doi: 10.1038/s41591-019-0512-5. Epub 2019 Jul 29. PubMed |
| Gene-edited murine cell lines for propagation of chronic wasting disease prions. Walia R, Ho CC, Lee C, Gilch S, Schatzl HM. Sci Rep. 2019 Aug 1;9(1):11151. doi: 10.1038/s41598-019-47629-z. PubMed |
| Characterization of the Importin-beta binding domain in nuclear import receptor KPNA7. Oostdyk LT, McConnell MJ, Paschal BM. Biochem J. 2019 Nov 15;476(21):3413-3434. doi: 10.1042/BCJ20190717. PubMed |
| Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth. Palomo-Guerrero M, Fado R, Casas M, Perez-Montero M, Baena M, Helmer PO, Dominguez JL, Roig A, Serra D, Hayen H, Stenmark H, Raiborg C, Casals N. Elife. 2019 Dec 23;8. pii: 51063. doi: 10.7554/eLife.51063. PubMed |
| Frizzled 1 and Wnt1 as new potential therapeutic targets in the traumatically injured spinal cord. Gonzalez P, Gonzalez-Fernandez C, Campos-Martin Y, Mollejo M, Carballosa-Gautam M, Marcillo A, Norenberg M, Rodriguez FJ. Cell Mol Life Sci. 2020 Jan 3. pii: 10.1007/s00018-019-03427-4. doi: 10.1007/s00018-019-03427-4. PubMed |
| Outside-in regulation of the readily releasable pool of synaptic vesicles by alpha2delta-1. Martinez San Segundo P, Terni B, Burgueno J, Monroy X, Dordal A, Merlos M, Llobet A. FASEB J. 2020 Jan;34(1):1362-1377. doi: 10.1096/fj.201901551R. Epub 2019 Nov 30. PubMed |
| PAX2 promotes epithelial ovarian cancer progression involving fatty acid metabolic reprogramming. Feng Y, Tang Y, Mao Y, Liu Y, Yao D, Yang L, Garson K, Vanderhyden BC, Wang Q. Int J Oncol. 2020 Mar;56(3):697-708. doi: 10.3892/ijo.2020.4958. Epub 2020 Jan 10. PubMed |
| The tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complex. Koo CZ, Harrison N, Noy PJ, Szyroka J, Matthews AL, Hsia HE, Muller SA, Tushaus J, Goulding J, Willis K, Apicella C, Cragoe B, Davis E, Keles M, Malinova A, McFarlane TA, Morrison PR, Nguyen HTH, Sykes MC, Ahmed H, Di Maio A, Seipold L, Saftig P, Cull E, Pliotas C, Rubinstein E, Poulter NS, Briddon SJ, Holliday ND, Lichtenthaler SF, Tomlinson MG. J Biol Chem. 2020 Feb 28. pii: RA120.012601. doi: 10.1074/jbc.RA120.012601. PubMed |
| Gli2 mediates the development of castrationresistant prostate cancer. Xia L, Bouamar H, Gu X, Zeballos C, Qin T, Wang B, Zhou Y, Wang Y, Yang J, Zhu H, Zhang W, Houghton PJ, Sun LZ. Int J Oncol. 2020 Jul;57(1):100-112. doi: 10.3892/ijo.2020.5044. Epub 2020 Apr 13. PubMed |
| Environment-Sensing Aryl Hydrocarbon Receptor Inhibits the Chondrogenic Fate of Modulated Smooth Muscle Cells in Atherosclerotic Lesions. Kim JB, Zhao Q, Nguyen T, Pjanic M, Cheng P, Wirka R, Travisano S, Nagao M, Kundu R, Quertermous T. Circulation. 2020 Aug 11;142(6):575-590. doi: 10.1161/CIRCULATIONAHA.120.045981. Epub 2020 May 22. PubMed |
| Age-associated genes in human mammary gland drive human breast cancer progression. Gu X, Wang B, Zhu H, Zhou Y, Horning AM, Huang TH, Chen Y, Houghton P, Lai Z, Michalek JE, Sun LZ. Breast Cancer Res. 2020 Jun 15;22(1):64. doi: 10.1186/s13058-020-01299-2. PubMed |
| Humulone Modulation of GABAA Receptors and Its Role in Hops Sleep-Promoting Activity. Benkherouf AY, Eerola K, Soini SL, Uusi-Oukari M. Front Neurosci. 2020 Oct 14;14:594708. doi: 10.3389/fnins.2020.594708. eCollection 2020. PubMed |
| Post-Transcriptional Regulation of PARP7 Protein Stability Is Controlled by Androgen Signaling. Kamata T, Yang CS, Melhuish TA, Frierson HF Jr, Wotton D, Paschal BM. Cells. 2021 Feb 9;10(2). pii: cells10020363. doi: 10.3390/cells10020363. PubMed |
| FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex. Zhou C, Chen D, Ren J, Huang D, Li R, Luo H, Guan C, Cao Y, Wang W. J Cell Mol Med. 2021 Mar;25(6):3051-3062. doi: 10.1111/jcmm.16351. Epub 2021 Feb 13. PubMed |
| Open-Label Study of the Influence of Food Containing the Royal Sun Mushroom, Agaricus brasiliensis KA21 (Agaricomycetes), on beta-Glucan-Specific Antibody Production in Healthy Human Volunteers. Yamanaka D, Shoda M, Matsubara T, Ishibashi KI, Motoi A, Motoi R, Motoi M, Ohno N, Adachi Y. Int J Med Mushrooms. 2021;23(2):13-28. doi: 10.1615/IntJMedMushrooms.2020037471. PubMed |
| HIF1alpha epigenetically repressed macrophages via CRISPR/Cas9-EZH2 system for enhanced cancer immunotherapy. Dong Y, Zhang S, Gao X, Yin D, Wang T, Li Z, Wan Z, Wei M, Luo Y, Yang G, Liu L. Bioact Mater. 2021 Feb 20;6(9):2870-2880. doi: 10.1016/j.bioactmat.2021.02.008. eCollection 2021 Sep. PubMed |
| CD33M inhibits microglial phagocytosis, migration and proliferation, but the Alzheimer's disease-protective variant CD33m stimulates phagocytosis and proliferation, and inhibits adhesion. Butler CA, Thornton P, Brown GC. J Neurochem. 2021 Jul;158(2):297-310. doi: 10.1111/jnc.15349. Epub 2021 Apr 5. PubMed |
| Engrailed-2 is a cell autonomous regulator of neurogenesis in cultured hippocampal neural stem cells. Durens M, Soliman M, Millonig J, DiCicco-Bloom E. Dev Neurobiol. 2021 Jul;81(5):724-735. doi: 10.1002/dneu.22824. Epub 2021 May 5. PubMed |
| Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2. Shi G, Chiramel AI, Majdoul S, Lai KK, Das S, Beare PA, Andresson T, Best SM, Compton AA. bioRxiv. 2021 Apr 16. doi: 10.1101/2021.04.15.440067. PubMed |
| Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly. Yang CS, Jividen K, Kamata T, Dworak N, Oostdyk L, Remlein B, Pourfarjam Y, Kim IK, Du KP, Abbas T, Sherman NE, Wotton D, Paschal BM. Nat Commun. 2021 May 11;12(1):2705. doi: 10.1038/s41467-021-23055-6. PubMed |
| RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness. Benitez S, Cordero A, Santamaria PG, Redondo-Pedraza J, Rocha AS, Collado-Sole A, Jimenez M, Sanz-Moreno A, Yoldi G, Santos JC, De Benedictis I, Gomez-Aleza C, Da Silva-Alvarez S, Troule K, Gomez-Lopez G, Alcazar N, Palmero I, Collado M, Serrano M, Gonzalez-Suarez E. Dev Cell. 2021 Jun 21;56(12):1727-1741.e7. doi: 10.1016/j.devcel.2021.04.022. Epub 2021 May 17. PubMed |
| Inhibitory affinity modulation of FcgammaRIIA ligand binding by glycosphingolipids by inside-out signaling. Okubo K, Brenner MD, Cullere X, Saggu G, Patchen ML, Bose N, Mihori S, Yuan Z, Lowell CA, Zhu C, Mayadas TN. Cell Rep. 2021 May 18;35(7):109142. doi: 10.1016/j.celrep.2021.109142. PubMed |
| Anti-tumor effects of an ID antagonist with no observed acquired resistance. Wojnarowicz PM, Escolano MG, Huang YH, Desai B, Chin Y, Shah R, Xu S, Yadav S, Yaklichkin S, Ouerfelli O, Soni RK, Philip J, Montrose DC, Healey JH, Rajasekhar VK, Garland WA, Ratiu J, Zhuang Y, Norton L, Rosen N, Hendrickson RC, Zhou XK, Iavarone A, Massague J, Dannenberg AJ, Lasorella A, Benezra R. NPJ Breast Cancer. 2021 May 24;7(1):58. doi: 10.1038/s41523-021-00266-0. PubMed |
| The Role of Smad2 in Adult Neuroplasticity as Seen through Hippocampal-Dependent Spatial Learning/Memory and Neurogenesis. Gradari S, Herrera A, Tezanos P, Fontan-Lozano A, Pons S, Trejo JL. J Neurosci. 2021 Aug 11;41(32):6836-6849. doi: 10.1523/JNEUROSCI.2619-20.2021. Epub 2021 Jul 1. PubMed |
| The RNase MCPIP3 promotes skin inflammation by orchestrating myeloid cytokine response. Liu B, Huang J, Ashraf A, Rahaman O, Lou J, Wang L, Cai P, Wen J, Anwaar S, Liu X, Ni H, Ganguly D, Zhao J, Yang CY. Nat Commun. 2021 Jul 2;12(1):4105. doi: 10.1038/s41467-021-24352-w. PubMed |
| Tumor burden limits bispecific antibody efficacy through T cell exhaustion averted by concurrent cytotoxic therapy. Meermeier EW, Welsh SJ, Sharik ME, Du MT, Garbitt VM, Riggs DL, Shi CX, Stein CK, Bergsagel M, Chau B, Wheeler ML, Bezman N, Wang F, Strop P, Bergsagel PL, Chesi M. Blood Cancer Discov. 2021 Jul;2(4):354-369. doi: 10.1158/2643-3230.BCD-21-0038. PubMed |
| CD13 orients the apical-basal polarity axis necessary for lumen formation. Wang LT, Rajah A, Brown CM, McCaffrey L. Nat Commun. 2021 Aug 4;12(1):4697. doi: 10.1038/s41467-021-24993-x. PubMed |
| The Phosphatidylserine Receptor TIM-1 Enhances Authentic Chikungunya Virus Cell Entry. Kirui J, Abidine Y, Lenman A, Islam K, Gwon YD, Lasswitz L, Evander M, Bally M, Gerold G. Cells. 2021 Jul 20;10(7). pii: cells10071828. doi: 10.3390/cells10071828. PubMed |
| Translational repression of NMD targets by GIGYF2 and EIF4E2. Zinshteyn B, Sinha NK, Enam SU, Koleske B, Green R. PLoS Genet. 2021 Oct 19;17(10):e1009813. doi: 10.1371/journal.pgen.1009813. eCollection 2021 Oct. PubMed |
| A Novel ZNF304/miR-183-5p/FOXO4 Pathway Regulates Cell Proliferation in Clear Cell Renal Carcinoma. Ren LX, Zeng BW, Zhu M, Zhao AN, Shi B, Zhang H, Wang DD, Gu JF, Yang Z. Front Oncol. 2021 Oct 7;11:710525. doi: 10.3389/fonc.2021.710525. eCollection 2021. PubMed |
| Evolutionary plasticity of SH3 domain binding by Nef proteins of the HIV-1/SIVcpz lentiviral lineage. Zhao Z, Fagerlund R, Tossavainen H, Hopfensperger K, Lotke R, Srinivasachar Badarinarayan S, Kirchhoff F, Permi P, Sato K, Sauter D, Saksela K. PLoS Pathog. 2021 Nov 15;17(11):e1009728. doi: 10.1371/journal.ppat.1009728. eCollection 2021 Nov. PubMed |
| A proximity proteomics screen in three-dimensional spheroid cultures identifies novel regulators of lumen formation. Wang LT, Proulx ME, Kim AD, Lelarge V, McCaffrey L. Sci Rep. 2021 Nov 23;11(1):22807. doi: 10.1038/s41598-021-02178-2. PubMed |
| Co-administration of human MSC overexpressing HIF-1alpha increases human CD34(+) cell engraftment in vivo. Preciado S, Sirerol-Piquer MS, Muntion S, Osugui L, Marti-Chillon GJ, Navarro-Bailon A, Sepulveda P, Sanchez-Guijo F. Stem Cell Res Ther. 2021 Dec 7;12(1):601. doi: 10.1186/s13287-021-02669-z. PubMed |
| Antidepressant and Antipsychotic Drugs Reduce Viral Infection by SARS-CoV-2 and Fluoxetine Shows Antiviral Activity Against the Novel Variants in vitro. Fred SM, Kuivanen S, Ugurlu H, Casarotto PC, Levanov L, Saksela K, Vapalahti O, Castren E. Front Pharmacol. 2022 Jan 19;12:755600. doi: 10.3389/fphar.2021.755600. eCollection 2021. PubMed |
| Monitoring Virus-Induced Stress Granule Dynamics Using Long-Term Live-Cell Imaging. Magg V, Klein P, Ruggieri A. Methods Mol Biol. 2022;2428:325-348. doi: 10.1007/978-1-0716-1975-9_20. PubMed |
| Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress. Liu X, Viswanadhapalli S, Kumar S, Lee TK, Moore A, Ma S, Chen L, Hsieh M, Li M, Sareddy GR, Parra K, Blatt EB, Reese TC, Zhao Y, Chang A, Yan H, Xu Z, Pratap UP, Liu Z, Roggero CM, Tan Z, Weintraub ST, Peng Y, Tekmal RR, Arteaga CL, Lippincott-Schwartz J, Vadlamudi RK, Ahn JM, Raj GV. Nat Cancer. 2022 Jul;3(7):866-884. doi: 10.1038/s43018-022-00389-8. Epub 2022 Jun 2. PubMed |
| Disturbing NLRP3 acetylation and inflammasome assembly inhibits androgen receptor-promoted inflammatory responses and prostate cancer progression. Zhao AN, Yang Z, Wang DD, Shi B, Zhang H, Bai Y, Yan BW, Zhang Y, Wen JK, Wang XL, Qu CB. FASEB J. 2022 Nov;36(11):e22602. doi: 10.1096/fj.202200673RRR. PubMed |
| The CRHR1/CREB/REST signaling cascade regulates mammalian embryonic neural stem cell properties. Kwon M, Lee JH, Yoon Y, Pleasure SJ, Yoon K. EMBO Rep. 2023 Feb 6;24(2):e55313. doi: 10.15252/embr.202255313. Epub 2022 Nov 22. PubMed |
| SF3B4 promotes Twist1 expression and clear cell renal cell carcinoma progression by facilitating the export of KLF 16 mRNA from the nucleus to the cytoplasm. Yang Z, Wang YX, Wen JK, Gao HT, Han ZW, Qi JC, Gu JF, Zhao CM, Zhang H, Shi B, Wang DD, Wang XL, Qu CB. Cell Death Dis. 2023 Jan 13;14(1):26. doi: 10.1038/s41419-022-05534-w. PubMed |
| Molecular mechanisms of coronary artery disease risk at the PDGFD locus. Kim HJ, Cheng P, Travisano S, Weldy C, Monteiro JP, Kundu R, Nguyen T, Sharma D, Shi H, Lin Y, Liu B, Haldar S, Jackson S, Quertermous T. Nat Commun. 2023 Feb 15;14(1):847. doi: 10.1038/s41467-023-36518-9. PubMed |
| Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury. Mohr ME, Li S, Trouten AM, Stairley RA, Roddy PL, Liu C, Zhang M, Sucov HM, Tao G. bioRxiv. 2023 Feb 8:2023.02.07.527364. doi: 10.1101/2023.02.07.527364. Preprint. PubMed |
| Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy. Sikder K, Phillips E, Zhong Z, Wang N, Saunders J, Mothy D, Kossenkov A, Schneider T, Nichtova Z, Csordas G, Margulies KB, Choi JC. bioRxiv. 2023 Jun 7:2023.02.14.528563. doi: 10.1101/2023.02.14.528563. Preprint. PubMed |
| Abrogation of stemness in osteosarcoma by the mithramycin analog EC-8042 is mediated by its ability to inhibit NOTCH-1 signaling. Estupinan O, Rey V, Tornin J, Murillo D, Gallego B, Huergo C, Blanco-Lorenzo V, Victoria Gonzalez M, Rodriguez A, Moris F, Gonzalez J, Ayllon V, Ramos-Mejia V, Bigas A, Rodriguez R. Biomed Pharmacother. 2023 Jun;162:114627. doi: 10.1016/j.biopha.2023.114627. Epub 2023 Apr 3. PubMed |
| CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation. Quandt E, Masip N, Hernandez-Ortega S, Sanchez-Botet A, Gasa L, Fernandez-Elorduy A, Plutta S, Martinez-Lainez JM, Bru S, Munoz-Torres PM, Floor M, Villa-Freixa J, Morris MC, Vidal A, Villanueva A, Clotet J, Ribeiro MPC. Mol Oncol. 2023 Jul;17(7):1228-1245. doi: 10.1002/1878-0261.13438. Epub 2023 May 31. PubMed |
| STAC1 is required for glioblastoma cell invasion and survival. Yoon Y, Yoo CR, Kim EC, Han J, Yoon K. Biochem Biophys Res Commun. 2023 Sep 24;674:75-82. doi: 10.1016/j.bbrc.2023.06.089. Epub 2023 Jun 29. PubMed |
| Regulation of young-adult neurogenesis and neuronal differentiation by neural cell adhesion molecule 2 (NCAM2). Ortega-Gasco A, Parcerisas A, Hino K, Herranz-Perez V, Ulloa F, Elias-Tersa A, Bosch M, Garcia-Verdugo JM, Simo S, Pujadas L, Soriano E. Cereb Cortex. 2023 Oct 14;33(21):10931-10948. doi: 10.1093/cercor/bhad340. PubMed |
| Transcriptional repression of beige fat innervation via a YAP/TAZ-S100B axis. Huang X, Li X, Shen H, Zhao Y, Zhou Z, Wang Y, Yao J, Xue K, Wu D, Qiu Y. Nat Commun. 2023 Nov 4;14(1):7102. doi: 10.1038/s41467-023-43021-8. PubMed |
| A partial human LCK defect causes a T cell immunodeficiency with intestinal inflammation. Lui VG, Hoenig M, Cabrera-Martinez B, Baxter RM, Garcia-Perez JE, Bailey O, Acharya A, Lundquist K, Capera J, Matusewicz P, Hartl FA, D'Abramo M, Alba J, Jacobsen EM, Niewolik D, Lorenz M, Pannicke U, Schulz AS, Debatin KM, Schamel WW, Minguet S, Gumbart JC, Dustin ML, Cambier JC, Schwarz K, Hsieh EWY. J Exp Med. 2024 Jan 1;221(1):e20230927. doi: 10.1084/jem.20230927. Epub 2023 Nov 14. PubMed |
| The matrix metalloproteinase ADAM10 supports hepatitis C virus entry and cell-to-cell spread via its sheddase activity. Carriqui-Madronal B, Sheldon J, Duven M, Stegmann C, Cirksena K, Wyler E, Zapatero-Belinchon FJ, Vondran FWR, Gerold G. PLoS Pathog. 2023 Nov 15;19(11):e1011759. doi: 10.1371/journal.ppat.1011759. eCollection 2023 Nov. PubMed |
| Cyclical palmitoylation regulates TLR9 signalling and systemic autoimmunity in mice. Ni H, Wang Y, Yao K, Wang L, Huang J, Xiao Y, Chen H, Liu B, Yang CY, Zhao J. Nat Commun. 2024 Jan 2;15(1):1. doi: 10.1038/s41467-023-43650-z. PubMed |
| The neuronal transcription factor MEIS2 is a calpain-2 protease target. Muller T, Reichlmeir M, Hau AC, Wittig I, Schulte D. J Cell Sci. 2024 Feb 15;137(4):jcs261482. doi: 10.1242/jcs.261482. Epub 2024 Feb 28. PubMed |
| Adaptive Darwinian off-target resistance mechanisms to selective RET inhibition in RET driven cancer. Subbiah V, Gouda MA, Iorgulescu JB, Dadu R, Patel K, Sherman S, Cabanillas M, Hu M, Castellanos LE, Amini B, Meric-Bernstam F, Shen T, Wu J. NPJ Precis Oncol. 2024 Mar 4;8(1):62. doi: 10.1038/s41698-024-00563-4. PubMed |
| Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury. Mohr ME, Li S, Trouten AM, Stairley RA, Roddy PL, Liu C, Zhang M, Sucov HM, Tao G. iScience. 2024 Feb 15;27(3):109219. doi: 10.1016/j.isci.2024.109219. eCollection 2024 Mar 15. PubMed |
| Tumor-Extrinsic Axl Expression Shapes an Inflammatory Microenvironment Independent of Tumor Cell Promoting Axl Signaling in Hepatocellular Carcinoma. Breitenecker K, Heiden D, Demmer T, Weber G, Primorac AM, Hedrich V, Ortmayr G, Gruenberger T, Starlinger P, Herndler-Brandstetter D, Barozzi I, Mikulits W. Int J Mol Sci. 2024 Apr 10;25(8):4202. doi: 10.3390/ijms25084202. PubMed |
| Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy. Sikder K, Phillips E, Zhong Z, Wang N, Saunders J, Mothy D, Kossenkov A, Schneider T, Nichtova Z, Csordas G, Margulies KB, Choi JC. Sci Adv. 2024 May 10;10(19):eadh0798. doi: 10.1126/sciadv.adh0798. Epub 2024 May 8. PubMed |
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