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VP16-ER alpha Citations (13)

Originally described in: Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors alpha and beta.
Chang C, Norris JD, Gron H, Paige LA, Hamilton PT, Kenan DJ, Fowlkes D, McDonnell DP Mol Cell Biol. 1999 Dec . 19(12):8226-39.
PubMed

Articles Citing VP16-ER alpha

Articles
TOX3 is a neuronal survival factor that induces transcription depending on the presence of CITED1 or phosphorylated CREB in the transcriptionally active complex. Dittmer S, Kovacs Z, Yuan SH, Siszler G, Kogl M, Summer H, Geerts A, Golz S, Shioda T, Methner A. J Cell Sci. 2011 Jan 15;124(Pt 2):252-60. doi: 10.1242/jcs.068759. Epub 2010 Dec 15. PubMed
Serine protease PRSS23 is upregulated by estrogen receptor alpha and associated with proliferation of breast cancer cells. Chan HS, Chang SJ, Wang TY, Ko HJ, Lin YC, Lin KT, Chang KM, Chuang YJ. PLoS One. 2012;7(1):e30397. doi: 10.1371/journal.pone.0030397. Epub 2012 Jan 23. PubMed
Estrogenic effect of three substituted deoxybenzoins. Chandrasekharan S, Bhaskar B, Muthiah R, Chandrasekharan AK, Ramamurthy V. Steroids. 2013 Feb;78(2):147-55. doi: 10.1016/j.steroids.2012.11.007. Epub 2012 Nov 23. PubMed
Contrasting hypoxic effects on breast cancer stem cell hierarchy is dependent on ER-alpha status. Harrison H, Rogerson L, Gregson HJ, Brennan KR, Clarke RB, Landberg G. Cancer Res. 2013 Feb 15;73(4):1420-33. doi: 10.1158/0008-5472.CAN-12-2505. Epub 2012 Dec 17. PubMed
The prolyl isomerase Pin1 acts synergistically with CDK2 to regulate the basal activity of estrogen receptor alpha in breast cancer. Lucchetti C, Caligiuri I, Toffoli G, Giordano A, Rizzolio F. PLoS One. 2013;8(2):e55355. doi: 10.1371/journal.pone.0055355. Epub 2013 Feb 4. PubMed
ERalpha-targeted therapy in ovarian cancer cells by a novel estradiol-platinum(II) hybrid. Brasseur K, Leblanc V, Fabi F, Parent S, Descoteaux C, Berube G, Asselin E. Endocrinology. 2013 Jul;154(7):2281-95. doi: 10.1210/en.2013-1083. Epub 2013 May 15. PubMed
Gender matters: estrogen receptor alpha (ERalpha) and histone deacetylase (HDAC) 1 and 2 control the gender-specific transcriptional regulation of human uridine diphosphate glucuronosyltransferases genes (UGT1A). Kalthoff S, Winkler A, Freiberg N, Manns MP, Strassburg CP. J Hepatol. 2013 Oct;59(4):797-804. doi: 10.1016/j.jhep.2013.05.028. Epub 2013 May 25. PubMed
Reversal of ER-beta silencing by chromatin modifying agents overrides acquired tamoxifen resistance. Pitta CA, Papageorgis P, Charalambous C, Constantinou AI. Cancer Lett. 2013 Sep 1;337(2):167-76. doi: 10.1016/j.canlet.2013.05.031. Epub 2013 Jun 7. PubMed
pRb controls estrogen receptor alpha protein stability and activity. Caligiuri I, Toffoli G, Giordano A, Rizzolio F. Oncotarget. 2013 Jun;4(6):875-83. PubMed
17beta-estradiol regulates giant vesicle formation via estrogen receptor-alpha in human breast cancer cells. Wright PK, Jones SB, Ardern N, Ward R, Clarke RB, Sotgia F, Lisanti MP, Landberg G, Lamb R. Oncotarget. 2014 May 30;5(10):3055-65. PubMed
DNA aptamer probes for detection of estrogen receptor alpha positive carcinomas. Sett A, Borthakur BB, Sharma JD, Kataki AC, Bora U. Transl Res. 2017 May;183:104-120.e2. doi: 10.1016/j.trsl.2016.12.008. Epub 2016 Dec 25. PubMed
Angelman syndrome-associated point mutations in the Zn-binding N-terminal (AZUL) domain of UBE3A ubiquitin ligase inhibit binding to the proteasome. Kuhnle S, Martinez-Noel G, Leclere F, Hayes SD, Harper JW, Howley PM. J Biol Chem. 2018 Sep 26. pii: RA118.004653. doi: 10.1074/jbc.RA118.004653. PubMed

Associated Plasmids

A conserved mechanism of sirtuin signalling through steroid hormone receptors. Bayele HK. Biosci Rep. 2019 Dec 20;39(12). pii: 221190. doi: 10.1042/BSR20193535. PubMed

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