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HA-NFAT1(4-460)-GFP Citations (21)

Originally described in: Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.
Aramburu J, Yaffe MB, Lopez-Rodriguez C, Cantley LC, Hogan PG, Rao A Science. 1999 Sep 24. 285(5436):2129-33.
PubMed Journal

Articles Citing HA-NFAT1(4-460)-GFP

Articles
Calcineurin-nuclear factor of activated T cells regulation of Krox-20 expression in Schwann cells requires elevation of intracellular cyclic AMP. Kipanyula MJ, Woodhoo A, Rahman M, Payne D, Jessen KR, Mirsky R. J Neurosci Res. 2013 Jan;91(1):105-15. doi: 10.1002/jnr.23131. Epub 2012 Oct 17. PubMed
The epithelial cell-derived atopic dermatitis cytokine TSLP activates neurons to induce itch. Wilson SR, The L, Batia LM, Beattie K, Katibah GE, McClain SP, Pellegrino M, Estandian DM, Bautista DM. Cell. 2013 Oct 10;155(2):285-95. doi: 10.1016/j.cell.2013.08.057. Epub 2013 Oct 3. PubMed
Phospho-STIM1 is a downstream effector that mediates the signaling triggered by IGF-1 in HEK293 cells. Tomas-Martin P, Lopez-Guerrero AM, Casas-Rua V, Pozo-Guisado E, Martin-Romero FJ. Cell Signal. 2015 Mar;27(3):545-54. doi: 10.1016/j.cellsig.2014.12.017. Epub 2015 Jan 3. PubMed
Inhibition of G-protein betagamma signaling enhances T cell receptor-stimulated interleukin 2 transcription in CD4+ T helper cells. Yost EA, Hynes TR, Hartle CM, Ott BJ, Berlot CH. PLoS One. 2015 Jan 28;10(1):e0116575. doi: 10.1371/journal.pone.0116575. eCollection 2015. PubMed
An imaging flow cytometry-based approach to measuring the spatiotemporal calcium mobilisation in activated T cells. Cerveira J, Begum J, Di Marco Barros R, van der Veen AG, Filby A. J Immunol Methods. 2015 May 9. pii: S0022-1759(15)00157-X. doi: 10.1016/j.jim.2015.04.030. PubMed
Light generation of intracellular Ca(2+) signals by a genetically encoded protein BACCS. Ishii T, Sato K, Kakumoto T, Miura S, Touhara K, Takeuchi S, Nakata T. Nat Commun. 2015 Aug 18;6:8021. doi: 10.1038/ncomms9021. PubMed

Associated Plasmids

Rapid flow cytometric measurement of protein inclusions and nuclear trafficking. Whiten DR, San Gil R, McAlary L, Yerbury JJ, Ecroyd H, Wilson MR. Sci Rep. 2016 Aug 12;6:31138. doi: 10.1038/srep31138. PubMed
Dnmt3a restrains mast cell inflammatory responses. Leoni C, Montagner S, Rinaldi A, Bertoni F, Polletti S, Balestrieri C, Monticelli S. Proc Natl Acad Sci U S A. 2017 Feb 6. pii: 201616420. doi: 10.1073/pnas.1616420114. PubMed

Associated Plasmids

Selective regulation of clathrin-mediated epidermal growth factor receptor signaling and endocytosis by phospholipase C and calcium. Delos Santos RC, Bautista S, Lucarelli S, Bone LN, Dayam RM, Abousawan J, Botelho RJ, Antonescu CN. Mol Biol Cell. 2017 Oct 15;28(21):2802-2818. doi: 10.1091/mbc.E16-12-0871. Epub 2017 Aug 16. PubMed
SOCE induced calcium overload regulates autophagy in acute pancreatitis via calcineurin activation. Zhu ZD, Yu T, Liu HJ, Jin J, He J. Cell Death Dis. 2018 Jan 19;9(2):50. doi: 10.1038/s41419-017-0073-9. PubMed
Spatially restricted subcellular Ca(2+) signaling downstream of store-operated calcium entry encoded by a cortical tunneling mechanism. Courjaret R, Dib M, Machaca K. Sci Rep. 2018 Jul 25;8(1):11214. doi: 10.1038/s41598-018-29562-9. PubMed
The CCT chaperonin is a novel regulator of Ca(2+) signaling through modulation of Orai1 trafficking. Hodeify R, Nandakumar M, Own M, Courjaret RJ, Graumann J, Hubrack SZ, Machaca K. Sci Adv. 2018 Sep 26;4(9):eaau1935. doi: 10.1126/sciadv.aau1935. eCollection 2018 Sep. PubMed
Cell shape regulates subcellular organelle location to control early Ca(2+) signal dynamics in vascular smooth muscle cells. Calizo RC, Bell MK, Ron A, Hu M, Bhattacharya S, Wong NJ, Janssen WGM, Perumal G, Pederson P, Scarlata S, Hone J, Azeloglu EU, Rangamani P, Iyengar R. Sci Rep. 2020 Oct 20;10(1):17866. doi: 10.1038/s41598-020-74700-x. PubMed
Omnitemporal choreographies of all five STIM/Orai and IP3Rs underlie the complexity of mammalian Ca(2+) signaling. Emrich SM, Yoast RE, Xin P, Arige V, Wagner LE, Hempel N, Gill DL, Sneyd J, Yule DI, Trebak M. Cell Rep. 2021 Mar 2;34(9):108760. doi: 10.1016/j.celrep.2021.108760. PubMed
Identification of pimavanserin tartrate as a potent Ca(2+)-calcineurin-NFAT pathway inhibitor for glioblastoma therapy. Liu ZZ, Liu XN, Fan RC, Jia YP, Zhang QK, Gao XQ, Wang YQ, Yang MQ, Ji LZ, Zhou YQ, Li HL, Li P, Tang B. Acta Pharmacol Sin. 2021 Nov;42(11):1860-1874. doi: 10.1038/s41401-021-00724-2. Epub 2021 Aug 6. PubMed
ORAI1-Regulated Gene Expression in Breast Cancer Cells: Roles for STIM1 Binding, Calcium Influx and Transcription Factor Translocation. Robitaille M, Chan SM, Peters AA, Dai L, So CL, Bong AHL, Sadras F, Roberts-Thomson SJ, Monteith GR. Int J Mol Sci. 2022 May 24;23(11). pii: ijms23115867. doi: 10.3390/ijms23115867. PubMed
NFAT1 Orchestrates Spinal Microglial Transcription and Promotes Microglial Proliferation via c-MYC Contributing to Nerve Injury-Induced Neuropathic Pain. Jiang BC, Ding TY, Guo CY, Bai XH, Cao DL, Wu XB, Sha WL, Jiang M, Wu LJ, Gao YJ. Adv Sci (Weinh). 2022 Sep;9(27):e2201300. doi: 10.1002/advs.202201300. Epub 2022 Jul 27. PubMed
Signaling Cascade Mediating the Effect of FTY720P on the Na(+)/K(+) ATPase in LLC-PK1. Khalil C, Hodeify R, Kreydiyyeh S. Cell Physiol Biochem. 2022 Aug 29;56(4):418-435. doi: 10.33594/000000561. PubMed
Chlamydia trachomatis suppresses host cell store-operated Ca(2+) entry and inhibits NFAT/calcineurin signaling. Chamberlain NB, Dimond Z, Hackstadt T. Sci Rep. 2022 Dec 10;12(1):21406. doi: 10.1038/s41598-022-25786-y. PubMed
STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration. Hammad AS, Yu F, Al-Hamaq J, Horgen FD, Machaca K. Cell Calcium. 2023 Sep;114:102779. doi: 10.1016/j.ceca.2023.102779. Epub 2023 Jun 28. PubMed
Specific Inhibition of Orai1-mediated Calcium Signalling Resolves Inflammation and Clears Bacteria in an ARDS Model. Ahmad S, Wrennall JA, Goriounova AS, Sekhri M, Iskarpatyoti JA, Ghosh A, Abdelwahab SH, Voeller A, Rai M, Mahida RY, Krajewski K, Ignar DM, Greenbaum A, Moran TP, Tilley SL, Thickett DR, Sassano MF, Tarran R. Am J Respir Crit Care Med. 2023 Nov 16. doi: 10.1164/rccm.202308-1393OC. PubMed

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