pX-evoCas9 Citations (3)
Originally described in: A highly specific SpCas9 variant is identified by in vivo screening in yeast.Casini A, Olivieri M, Petris G, Montagna C, Reginato G, Maule G, Lorenzin F, Prandi D, Romanel A, Demichelis F, Inga A, Cereseto A Nat Biotechnol. 2018 Jan 29. pii: nbt.4066. doi: 10.1038/nbt.4066. PubMed Journal
Articles Citing pX-evoCas9
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Directed evolution of CRISPR-Cas9 to increase its specificity.
Lee JK, Jeong E, Lee J, Jung M, Shin E, Kim YH, Lee K, Jung I, Kim D, Kim S, Kim JS.
Nat Commun. 2018 Aug 6;9(1):3048. doi: 10.1038/s41467-018-05477-x.
PubMed
Associated Plasmids |
Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9.
Choi GCG, Zhou P, Yuen CTL, Chan BKC, Xu F, Bao S, Chu HY, Thean D, Tan K, Wong KH, Zheng Z, Wong ASL.
Nat Methods. 2019 Aug;16(8):722-730. doi: 10.1038/s41592-019-0473-0. Epub 2019 Jul 15.
PubMed
Associated Plasmids |
| Quantitative assessment of engineered Cas9 variants for target specificity enhancement by single-molecule reaction pathway analysis. Bak SY, Jung Y, Park J, Sung K, Jang HK, Bae S, Kim SK. Nucleic Acids Res. 2021 Nov 8;49(19):11312-11322. doi: 10.1093/nar/gkab858. PubMed |
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