pCXLE-hOCT3/4-shp53-F Citations (290)
Originally described in: A more efficient method to generate integration-free human iPS cells.Okita K, Matsumura Y, Sato Y, Okada A, Morizane A, Okamoto S, Hong H, Nakagawa M, Tanabe K, Tezuka KI, Shibata T, Kunisada T, Takahashi M, Takahashi J, Saji H, Yamanaka S Nat Methods. 2011 May;8(5):409-12 PubMed Journal
Articles Citing pCXLE-hOCT3/4-shp53-F
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Conversion of human fibroblasts to angioblast-like progenitor cells. Kurian L, Sancho-Martinez I, Nivet E, Aguirre A, Moon K, Pendaries C, Volle-Challier C, Bono F, Herbert JM, Pulecio J, Xia Y, Li M, Montserrat N, Ruiz S, Dubova I, Rodriguez C, Denli AM, Boscolo FS, Thiagarajan RD, Gage FH, Loring JF, Laurent LC, Izpisua Belmonte JC. Nat Methods. 2013 Jan;10(1):77-83. doi: 10.1038/nmeth.2255. Epub 2012 Dec 2. PubMed |
To clone or not to clone? Induced pluripotent stem cells can be generated in bulk culture. Willmann CA, Hemeda H, Pieper LA, Lenz M, Qin J, Joussen S, Sontag S, Wanek P, Denecke B, Schuler HM, Zenke M, Wagner W. PLoS One. 2013 May 29;8(5):e65324. doi: 10.1371/journal.pone.0065324. Print 2013. PubMed |
Transcriptome comparison of human neurons generated using induced pluripotent stem cells derived from dental pulp and skin fibroblasts. Chen J, Lin M, Foxe JJ, Pedrosa E, Hrabovsky A, Carroll R, Zheng D, Lachman HM. PLoS One. 2013 Oct 3;8(10):e75682. doi: 10.1371/journal.pone.0075682. eCollection 2013. PubMed |
A systematic evaluation of integration free reprogramming methods for deriving clinically relevant patient specific induced pluripotent stem (iPS) cells. Goh PA, Caxaria S, Casper C, Rosales C, Warner TT, Coffey PJ, Nathwani AC. PLoS One. 2013 Nov 26;8(11):e81622. doi: 10.1371/journal.pone.0081622. eCollection 2013. PubMed |
Chemically defined generation of human cardiomyocytes. Burridge PW, Matsa E, Shukla P, Lin ZC, Churko JM, Ebert AD, Lan F, Diecke S, Huber B, Mordwinkin NM, Plews JR, Abilez OJ, Cui B, Gold JD, Wu JC. Nat Methods. 2014 Aug;11(8):855-60. doi: 10.1038/nmeth.2999. Epub 2014 Jun 15. PubMed |
Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs. Liu GH, Suzuki K, Li M, Qu J, Montserrat N, Tarantino C, Gu Y, Yi F, Xu X, Zhang W, Ruiz S, Plongthongkum N, Zhang K, Masuda S, Nivet E, Tsunekawa Y, Soligalla RD, Goebl A, Aizawa E, Kim NY, Kim J, Dubova I, Li Y, Ren R, Benner C, del Sol A, Bueren J, Trujillo JP, Surralles J, Cappelli E, Dufour C, Esteban CR, Izpisua Belmonte JC. Nat Commun. 2014 Jul 7;5:4330. doi: 10.1038/ncomms5330. PubMed |
Transient p53 suppression increases reprogramming of human fibroblasts without affecting apoptosis and DNA damage. Rasmussen MA, Holst B, Tumer Z, Johnsen MG, Zhou S, Stummann TC, Hyttel P, Clausen C. Stem Cell Reports. 2014 Sep 9;3(3):404-13. doi: 10.1016/j.stemcr.2014.07.006. Epub 2014 Aug 21. PubMed |
Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells. Schwarz N, Carr AJ, Lane A, Moeller F, Chen LL, Aguila M, Nommiste B, Muthiah MN, Kanuga N, Wolfrum U, Nagel-Wolfrum K, da Cruz L, Coffey PJ, Cheetham ME, Hardcastle AJ. Hum Mol Genet. 2015 Feb 15;24(4):972-86. doi: 10.1093/hmg/ddu509. Epub 2014 Oct 6. PubMed |
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids. McCracken KW, Cata EM, Crawford CM, Sinagoga KL, Schumacher M, Rockich BE, Tsai YH, Mayhew CN, Spence JR, Zavros Y, Wells JM. Nature. 2014 Dec 18;516(7531):400-4. doi: 10.1038/nature13863. Epub 2014 Oct 29. PubMed |
Laser-assisted generation of human induced pluripotent stem cells. Liu Y, Wu D, Lao D, Peterson C, Hohenstein Elliott KA, Snyder EY. Curr Protoc Stem Cell Biol. 2014 Nov 3;31:4A.7.1-4A.7.15. doi: 10.1002/9780470151808.sc04a07s31. PubMed |
Efficient iPS cell generation from blood using episomes and HDAC inhibitors. Hubbard JJ, Sullivan SK, Mills JA, Hayes BJ, Torok-Storb BJ, Ramakrishnan A. J Vis Exp. 2014 Oct 28;(92):e52009. doi: 10.3791/52009. PubMed |
A comparison of non-integrating reprogramming methods. Schlaeger TM, Daheron L, Brickler TR, Entwisle S, Chan K, Cianci A, DeVine A, Ettenger A, Fitzgerald K, Godfrey M, Gupta D, McPherson J, Malwadkar P, Gupta M, Bell B, Doi A, Jung N, Li X, Lynes MS, Brookes E, Cherry AB, Demirbas D, Tsankov AM, Zon LI, Rubin LL, Feinberg AP, Meissner A, Cowan CA, Daley GQ. Nat Biotechnol. 2015 Jan;33(1):58-63. doi: 10.1038/nbt.3070. Epub 2014 Dec 1. PubMed |
Dynamic transcriptional and epigenomic reprogramming from pediatric nasal epithelial cells to induced pluripotent stem cells. Ji H, Zhang X, Oh S, Mayhew CN, Ulm A, Somineni HK, Ericksen M, Wells JM, Khurana Hershey GK. J Allergy Clin Immunol. 2015 Jan;135(1):236-44. doi: 10.1016/j.jaci.2014.08.038. Epub 2014 Oct 14. PubMed |
Optimized Generation of Functional Neutrophils and Macrophages from Patient-Specific Induced Pluripotent Stem Cells: Ex Vivo Models of X(0)-Linked, AR22(0)- and AR47(0)- Chronic Granulomatous Diseases. Brault J, Goutagny E, Telugu N, Shao K, Baquie M, Satre V, Coutton C, Grunwald D, Brion JP, Barlogis V, Stephan JL, Plantaz D, Hescheler J, Krause KH, Saric T, Stasia MJ. Biores Open Access. 2014 Dec 1;3(6):311-26. doi: 10.1089/biores.2014.0045. PubMed |
A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease. Tidball AM, Bryan MR, Uhouse MA, Kumar KK, Aboud AA, Feist JE, Ess KC, Neely MD, Aschner M, Bowman AB. Hum Mol Genet. 2015 Apr 1;24(7):1929-44. doi: 10.1093/hmg/ddu609. Epub 2014 Dec 8. PubMed |
Ultrastructural visualization of the Mesenchymal-to-Epithelial Transition during reprogramming of human fibroblasts to induced pluripotent stem cells. Hoffding MK, Hyttel P. Stem Cell Res. 2015 Jan;14(1):39-53. doi: 10.1016/j.scr.2014.11.003. Epub 2014 Nov 29. PubMed |
Modeling Axonal Phenotypes with Human Pluripotent Stem Cells. Denton KR, Xu CC, Li XJ. Methods Mol Biol. 2014 Dec 18. PubMed |
Generation of Integration-Free Patient Specific iPS Cells Using Episomal Plasmids Under Feeder Free Conditions. Caxaria S, Arthold S, Nathwani AC, Goh PA. Methods Mol Biol. 2015 Feb 21. PubMed |
HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity. Mattis VB, Tom C, Akimov S, Saeedian J, Ostergaard ME, Southwell AL, Doty CN, Ornelas L, Sahabian A, Lenaeus L, Mandefro B, Sareen D, Arjomand J, Hayden MR, Ross CA, Svendsen CN. Hum Mol Genet. 2015 Jun 1;24(11):3257-71. doi: 10.1093/hmg/ddv080. Epub 2015 Mar 3. PubMed |
Chromatin fibers are formed by heterogeneous groups of nucleosomes in vivo. Ricci MA, Manzo C, Garcia-Parajo MF, Lakadamyali M, Cosma MP. Cell. 2015 Mar 12;160(6):1145-58. doi: 10.1016/j.cell.2015.01.054. PubMed |
Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3-dioxygenase1. Romani R, Pirisinu I, Calvitti M, Pallotta MT, Gargaro M, Bistoni G, Vacca C, Di Michele A, Orabona C, Rosati J, Pirro M, Giovagnoli S, Matino D, Prontera P, Rosi G, Grohmann U, Talesa VN, Donti E, Puccetti P, Fallarino F. J Cell Mol Med. 2015 Jul;19(7):1593-605. doi: 10.1111/jcmm.12534. Epub 2015 Mar 17. PubMed |
An alternative pluripotent state confers interspecies chimaeric competency. Wu J, Okamura D, Li M, Suzuki K, Luo C, Ma L, He Y, Li Z, Benner C, Tamura I, Krause MN, Nery JR, Du T, Zhang Z, Hishida T, Takahashi Y, Aizawa E, Kim NY, Lajara J, Guillen P, Campistol JM, Esteban CR, Ross PJ, Saghatelian A, Ren B, Ecker JR, Izpisua Belmonte JC. Nature. 2015 May 21;521(7552):316-21. doi: 10.1038/nature14413. Epub 2015 May 6. PubMed |
Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature. Thomas SM, Kagan C, Pavlovic BJ, Burnett J, Patterson K, Pritchard JK, Gilad Y. PLoS Genet. 2015 May 7;11(5):e1005216. doi: 10.1371/journal.pgen.1005216. eCollection 2015 May. PubMed |
Differentiation of blood T cells: Reprogramming human induced pluripotent stem cells into neuronal cells. Tsai PH, Chang YC, Lee YY, Ko YL, Yang YH, Lin CF, Chang YL, Yu WC, Shih YH, Chen MT. J Chin Med Assoc. 2015 Jun;78(6):353-9. doi: 10.1016/j.jcma.2015.03.007. Epub 2015 May 26. PubMed |
Mitochondrial respiratory dysfunction caused by a heteroplasmic mitochondrial DNA mutation blocks cellular reprogramming. Yokota M, Hatakeyama H, Okabe S, Ono Y, Goto Y. Hum Mol Genet. 2015 Aug 15;24(16):4698-709. doi: 10.1093/hmg/ddv201. Epub 2015 May 29. PubMed |
Reprogramming fibroblasts toward cardiomyocytes, neural stem cells and hepatocytes by cell activation and signaling-directed lineage conversion. Zhu S, Wang H, Ding S. Nat Protoc. 2015 Jul;10(7):959-73. doi: 10.1038/nprot.2015.059. Epub 2015 Jun 4. PubMed |
A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics. Gallego Romero I, Pavlovic BJ, Hernando-Herraez I, Zhou X, Ward MC, Banovich NE, Kagan CL, Burnett JE, Huang CH, Mitrano A, Chavarria CI, Friedrich Ben-Nun I, Li Y, Sabatini K, Leonardo TR, Parast M, Marques-Bonet T, Laurent LC, Loring JF, Gilad Y. Elife. 2015 Jun 23;4:e07103. doi: 10.7554/eLife.07103. PubMed |
Transgene-Free Disease-Specific iPSC Generation from Fibroblasts and Peripheral Blood Mononuclear Cells. Fidan K, Ebrahimi A, Caglayan OH, Ozcimen B, Onder TT. Methods Mol Biol. 2016;1353:215-31. doi: 10.1007/7651_2015_278. PubMed |
Generation of Induced Pluripotent Stem Cells from Frozen Buffy Coats using Non-integrating Episomal Plasmids. Meraviglia V, Zanon A, Lavdas AA, Schwienbacher C, Silipigni R, Di Segni M, Chen HS, Pramstaller PP, Hicks AA, Rossini A. J Vis Exp. 2015 Jun 5;(100):e52885. doi: 10.3791/52885. PubMed |
MicroRNA Profiling of Neurons Generated Using Induced Pluripotent Stem Cells Derived from Patients with Schizophrenia and Schizoaffective Disorder, and 22q11.2 Del. Zhao D, Lin M, Chen J, Pedrosa E, Hrabovsky A, Fourcade HM, Zheng D, Lachman HM. PLoS One. 2015 Jul 14;10(7):e0132387. doi: 10.1371/journal.pone.0132387. eCollection 2015. PubMed |
Generation and Characterization of Induced Pluripotent Stem Cells from Patients with mtDNA Mutations. Hamalainen RH, Suomalainen A. Methods Mol Biol. 2016;1353:65-75. doi: 10.1007/7651_2015_258. PubMed |
Molecular pathomechanisms and cell-type-specific disease phenotypes of MELAS caused by mutant mitochondrial tRNA(Trp). Hatakeyama H, Katayama A, Komaki H, Nishino I, Goto Y. Acta Neuropathol Commun. 2015 Aug 22;3:52. doi: 10.1186/s40478-015-0227-x. PubMed |
Generation of Integration-free Human Induced Pluripotent Stem Cells Using Hair-derived Keratinocytes. Hung SS, Pebay A, Wong RC. J Vis Exp. 2015 Aug 20;(102):e53174. doi: 10.3791/53174. PubMed |
A Comparative View on Easy to Deploy non-Integrating Methods for Patient-Specific iPSC Production. Manzini S, Viiri LE, Marttila S, Aalto-Setala K. Stem Cell Rev. 2015 Dec;11(6):900-8. doi: 10.1007/s12015-015-9619-3. PubMed |
Practical Integration-Free Episomal Methods for Generating Human Induced Pluripotent Stem Cells. Kime C, Rand TA, Ivey KN, Srivastava D, Yamanaka S, Tomoda K. Curr Protoc Hum Genet. 2015 Oct 6;87:21.2.1-21.2.21. doi: 10.1002/0471142905.hg2102s87. PubMed |
Human iPS Cell-Derived Neurons Uncover the Impact of Increased Ras Signaling in Costello Syndrome. Rooney GE, Goodwin AF, Depeille P, Sharir A, Schofield CM, Yeh E, Roose JP, Klein OD, Rauen KA, Weiss LA, Ullian EM. J Neurosci. 2016 Jan 6;36(1):142-52. doi: 10.1523/JNEUROSCI.1547-15.2016. PubMed |
C9orf72 promoter hypermethylation is reduced while hydroxymethylation is acquired during reprogramming of ALS patient cells. Esanov R, Belle KC, van Blitterswijk M, Belzil VV, Rademakers R, Dickson DW, Petrucelli L, Boylan KB, Dykxhoorn DM, Wuu J, Benatar M, Wahlestedt C, Zeier Z. Exp Neurol. 2016 Mar;277:171-7. doi: 10.1016/j.expneurol.2015.12.022. Epub 2015 Dec 31. PubMed |
Overcoming Pluripotent Stem Cell Dependence on the Repair of Endogenous DNA Damage. Chlon TM, Ruiz-Torres S, Maag L, Mayhew CN, Wikenheiser-Brokamp KA, Davies SM, Mehta P, Myers KC, Wells JM, Wells SI. Stem Cell Reports. 2016 Jan 12;6(1):44-54. doi: 10.1016/j.stemcr.2015.12.001. PubMed |
Reduced CYFIP1 in Human Neural Progenitors Results in Dysregulation of Schizophrenia and Epilepsy Gene Networks. Nebel RA, Zhao D, Pedrosa E, Kirschen J, Lachman HM, Zheng D, Abrahams BS. PLoS One. 2016 Jan 29;11(1):e0148039. doi: 10.1371/journal.pone.0148039. eCollection 2016. PubMed |
Genomic Instability Associated with p53 Knockdown in the Generation of Huntington's Disease Human Induced Pluripotent Stem Cells. Tidball AM, Neely MD, Chamberlin R, Aboud AA, Kumar KK, Han B, Bryan MR, Aschner M, Ess KC, Bowman AB. PLoS One. 2016 Mar 16;11(3):e0150372. doi: 10.1371/journal.pone.0150372. eCollection 2016. PubMed |
Generation of integration-free induced pluripotent stem cells from a patient with Familial Mediterranean Fever (FMF). Fidan K, Kavaklioglu G, Ebrahimi A, Ozlu C, Ay NZ, Ruacan A, Gul A, Onder TT. Stem Cell Res. 2015 Nov;15(3):694-6. doi: 10.1016/j.scr.2015.10.018. Epub 2015 Nov 2. PubMed |
Transcriptional Reactivation of OTX2, RX1 and SIX3 during Reprogramming Contributes to the Generation of RPE Cells from Human iPSCs. Li P, Sun X, Ma Z, Liu Y, Jin Y, Ge R, Hao L, Ma Y, Han S, Sun H, Zhang M, Li R, Li T, Shen L. Int J Biol Sci. 2016 Feb 20;12(5):505-17. doi: 10.7150/ijbs.14212. eCollection 2016. PubMed |
Site-specific genome editing for correction of induced pluripotent stem cells derived from dominant dystrophic epidermolysis bullosa. Shinkuma S, Guo Z, Christiano AM. Proc Natl Acad Sci U S A. 2016 May 17;113(20):5676-81. doi: 10.1073/pnas.1512028113. Epub 2016 May 3. PubMed |
Multiple Sclerosis Patient-Specific Primary Neurons Differentiated from Urinary Renal Epithelial Cells via Induced Pluripotent Stem Cells. Massa MG, Gisevius B, Hirschberg S, Hinz L, Schmidt M, Gold R, Prochnow N, Haghikia A. PLoS One. 2016 May 9;11(5):e0155274. doi: 10.1371/journal.pone.0155274. eCollection 2016. PubMed |
Myocardial commitment from human pluripotent stem cells: Rapid production of human heart grafts. Garreta E, de Onate L, Fernandez-Santos ME, Oria R, Tarantino C, Climent AM, Marco A, Samitier M, Martinez E, Valls-Margarit M, Matesanz R, Taylor DA, Fernandez-Aviles F, Izpisua Belmonte JC, Montserrat N. Biomaterials. 2016 Aug;98:64-78. doi: 10.1016/j.biomaterials.2016.04.003. Epub 2016 Apr 26. PubMed |
Concurrent progress of reprogramming and gene correction to overcome therapeutic limitation of mutant ALK2-iPSC. Kim BY, Jeong S, Lee SY, Lee SM, Gweon EJ, Ahn H, Kim J, Chung SK. Exp Mol Med. 2016 Jun 3;48(6):e237. doi: 10.1038/emm.2016.43. PubMed |
Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a P301L mutation in microtubule-associated protein tau (MAPT). Rasmussen MA, Hjermind LE, Hasholt LF, Waldemar G, Nielsen JE, Clausen C, Hyttel P, Holst B. Stem Cell Res. 2016 Jan;16(1):70-4. doi: 10.1016/j.scr.2015.12.008. Epub 2015 Dec 12. PubMed |
Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a R406W mutation in microtubule-associated protein tau (MAPT). Rasmussen MA, Hjermind LE, Hasholt LF, Waldemar G, Nielsen JE, Clausen C, Hyttel P, Holst B. Stem Cell Res. 2016 Jan;16(1):75-8. doi: 10.1016/j.scr.2015.12.006. Epub 2015 Dec 12. PubMed |
Induced pluripotent stem cells (iPSCs) derived from a pre-symptomatic carrier of a R406W mutation in microtubule-associated protein tau (MAPT) causing frontotemporal dementia. Rasmussen MA, Hjermind LE, Hasholt LF, Waldemar G, Nielsen JE, Clausen C, Hyttel P, Holst B. Stem Cell Res. 2016 Jan;16(1):105-9. doi: 10.1016/j.scr.2015.12.012. Epub 2015 Dec 23. PubMed |
Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1. Tubsuwan A, Pires C, Rasmussen MA, Schmid B, Nielsen JE, Hjermind LE, Hall V, Nielsen TT, Waldemar G, Hyttel P, Clausen C, Kitiyanant N, Freude KK, Holst B. Stem Cell Res. 2016 Jan;16(1):110-2. doi: 10.1016/j.scr.2015.12.015. Epub 2015 Dec 28. PubMed |
Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H271. Marthaler AG, Tubsuwan A, Schmid B, Poulsen UB, Hyttel P, Nielsen JE, Nielsen TT, Holst B. Stem Cell Res. 2016 Jan;16(1):159-61. doi: 10.1016/j.scr.2015.12.027. Epub 2016 Jan 3. PubMed |
Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H196. Marthaler AG, Schmid B, Tubsuwan A, Poulsen UB, Engelbrecht AF, Mau-Holzmann UA, Hyttel P, Nielsen JE, Nielsen TT, Holst B. Stem Cell Res. 2016 Jan;16(1):162-5. doi: 10.1016/j.scr.2015.12.031. Epub 2016 Jan 3. PubMed |
Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H266. Marthaler AG, Schmid B, Tubsuwan A, Poulsen UB, Hyttel P, Nielsen TT, Nielsen JE, Holst B. Stem Cell Res. 2016 Jan;16(1):166-9. doi: 10.1016/j.scr.2015.12.029. Epub 2016 Jan 3. PubMed |
Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H271. Marthaler AG, Schmid B, Tubsuwan A, Poulsen UB, Engelbrecht AF, Mau-Holzmann UA, Hyttel P, Nielsen JE, Nielsen TT, Holst B. Stem Cell Res. 2016 Jan;16(1):180-3. doi: 10.1016/j.scr.2015.12.028. Epub 2016 Jan 3. PubMed |
Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H196. Marthaler AG, Schmid B, Tubsuwan A, Poulsen UB, Hyttel P, Nielsen TT, Nielsen JE, Holst B. Stem Cell Res. 2016 Jan;16(1):199-201. doi: 10.1016/j.scr.2015.12.049. Epub 2016 Jan 15. PubMed |
Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H266. Marthaler AG, Tubsuwan A, Schmid B, Poulsen UB, Engelbrecht AF, Mau-Holzmann UA, Hyttel P, Nielsen TT, Nielsen JE, Holst B. Stem Cell Res. 2016 Jan;16(1):202-5. doi: 10.1016/j.scr.2015.12.048. Epub 2016 Jan 15. PubMed |
Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying an A79V mutation in PSEN1. Li T, Pires C, Nielsen TT, Waldemar G, Hjermind LE, Nielsen JE, Dinnyes A, Hyttel P, Freude KK. Stem Cell Res. 2016 Mar;16(2):229-32. doi: 10.1016/j.scr.2016.01.002. Epub 2016 Jan 14. PubMed |
Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a M146I mutation in PSEN1. Li T, Pires C, Nielsen TT, Waldemar G, Hjermind LE, Nielsen JE, Dinnyes A, Holst B, Hyttel P, Freude KK. Stem Cell Res. 2016 Mar;16(2):334-7. doi: 10.1016/j.scr.2016.01.001. Epub 2016 Jan 14. PubMed |
A human pluripotent stem cell model of catecholaminergic polymorphic ventricular tachycardia recapitulates patient-specific drug responses. Preininger MK, Jha R, Maxwell JT, Wu Q, Singh M, Wang B, Dalal A, Mceachin ZT, Rossoll W, Hales CM, Fischbach PS, Wagner MB, Xu C. Dis Model Mech. 2016 Sep 1;9(9):927-39. doi: 10.1242/dmm.026823. Epub 2016 Aug 4. PubMed |
Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific heterozygous mutation in CHMP2B. Zhang Y, Schmid B, Nielsen TT, Nielsen JE, Clausen C, Hyttel P, Holst B, Freude KK. Stem Cell Res. 2016 Jun 16;17(1):148-150. doi: 10.1016/j.scr.2016.06.004. PubMed |
Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific homozygous mutation in CHMP2B. Zhang Y, Schmid B, Nielsen TT, Nielsen JE, Clausen C, Hyttel P, Holst B, Freude KK. Stem Cell Res. 2016 Jun 16;17(1):151-153. doi: 10.1016/j.scr.2016.06.005. PubMed |
Modeling and correction of structural variations in patient-derived iPSCs using CRISPR/Cas9. Park CY, Sung JJ, Choi SH, Lee DR, Park IH, Kim DW. Nat Protoc. 2016 Nov;11(11):2154-2169. doi: 10.1038/nprot.2016.129. Epub 2016 Oct 6. PubMed |
Derivation of induced pluripotent stem cells from a familial Alzheimer's disease patient carrying the L282F mutation in presenilin 1. Poon A, Li T, Pires C, Nielsen TT, Nielsen JE, Holst B, Dinnyes A, Hyttel P, Freude KK. Stem Cell Res. 2016 Sep 28;17(3):470-473. doi: 10.1016/j.scr.2016.09.016. PubMed |
Generation of induced pluripotent stem cells derived from a 77-year-old healthy woman as control for age related diseases. Nimsanor N, Jorring I, Rasmussen MA, Clausen C, Mau-Holzmann UA, Bus C, Hoffmann SA, Gasser T, Kluba T, Holst B, Schmid B. Stem Cell Res. 2016 Sep 28;17(3):550-552. doi: 10.1016/j.scr.2016.09.019. PubMed |
Plasmid-Based Generation of Induced Neural Stem Cells from Adult Human Fibroblasts. Capetian P, Azmitia L, Pauly MG, Krajka V, Stengel F, Bernhardi EM, Klett M, Meier B, Seibler P, Stanslowsky N, Moser A, Knopp A, Gillessen-Kaesbach G, Nikkhah G, Wegner F, Dobrossy M, Klein C. Front Cell Neurosci. 2016 Oct 24;10:245. eCollection 2016. PubMed |
Integrative transcriptome network analysis of iPSC-derived neurons from schizophrenia and schizoaffective disorder patients with 22q11.2 deletion. Lin M, Pedrosa E, Hrabovsky A, Chen J, Puliafito BR, Gilbert SR, Zheng D, Lachman HM. BMC Syst Biol. 2016 Nov 15;10(1):105. PubMed |
Generation of a gene-corrected isogenic control cell line from an Alzheimer's disease patient iPSC line carrying a A79V mutation in PSEN1. Pires C, Schmid B, Petraeus C, Poon A, Nimsanor N, Nielsen TT, Waldemar G, Hjermind LE, Nielsen JE, Hyttel P, Freude KK. Stem Cell Res. 2016 Sep;17(2):285-288. doi: 10.1016/j.scr.2016.08.002. Epub 2016 Aug 7. PubMed |
Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium. Du J, Yanagida A, Knight K, Engel AL, Vo AH, Jankowski C, Sadilek M, Tran VT, Manson MA, Ramakrishnan A, Hurley JB, Chao JR. Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14710-14715. doi: 10.1073/pnas.1604572113. Epub 2016 Dec 1. PubMed |
Generation of an isogenic, gene-corrected iPSC line from a symptomatic 59-year-old female patient with frontotemporal dementia caused by an R406W mutation in the microtubule associated protein tau (MAPT) gene. Nimsanor N, Poulsen U, Rasmussen MA, Clausen C, Mau-Holzmann UA, Nielsen JE, Nielsen TT, Hyttel P, Holst B, Schmid B. Stem Cell Res. 2016 Sep 28;17(3):576-579. doi: 10.1016/j.scr.2016.09.020. PubMed |
Generation of an iPSC line from a patient with tyrosine hydroxylase (TH) deficiency: TH-1 iPSC. Jung-Klawitter S, Blau N, Sebe A, Ebersold J, Gohring G, Opladen T. Stem Cell Res. 2016 Oct 26;17(3):580-583. doi: 10.1016/j.scr.2016.10.008. PubMed |
Generation of an isogenic, gene-corrected iPSC line from a pre-symptomatic 28-year-old woman with an R406W mutation in the microtubule associated protein tau (MAPT) gene. Nimsanor N, Poulsen U, Rasmussen MA, Clausen C, Mau-Holzmann UA, Nielsen JE, Nielsen TT, Hyttel P, Holst B, Schmid B. Stem Cell Res. 2016 Sep 28;17(3):600-602. doi: 10.1016/j.scr.2016.09.024. PubMed |
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis. Ang YS, Rivas RN, Ribeiro AJ, Srivas R, Rivera J, Stone NR, Pratt K, Mohamed TM, Fu JD, Spencer CI, Tippens ND, Li M, Narasimha A, Radzinsky E, Moon-Grady AJ, Yu H, Pruitt BL, Snyder MP, Srivastava D. Cell. 2016 Dec 15;167(7):1734-1749.e22. doi: 10.1016/j.cell.2016.11.033. PubMed |
Mitochondrial respiratory dysfunction disturbs neuronal and cardiac lineage commitment of human iPSCs. Yokota M, Hatakeyama H, Ono Y, Kanazawa M, Goto YI. Cell Death Dis. 2017 Jan 12;8(1):e2551. doi: 10.1038/cddis.2016.484. PubMed |
Systematic evaluation of markers used for the identification of human induced pluripotent stem cells. Bharathan SP, Manian KV, Aalam SM, Palani D, Deshpande PA, Pratheesh MD, Srivastava A, Velayudhan SR. Biol Open. 2017 Jan 15;6(1):100-108. doi: 10.1242/bio.022111. PubMed |
Low dose resveratrol ameliorates mitochondrial respiratory dysfunction and enhances cellular reprogramming. Mizuguchi Y, Hatakeyama H, Sueoka K, Tanaka M, Goto YI. Mitochondrion. 2017 May;34:43-48. doi: 10.1016/j.mito.2016.12.006. Epub 2017 Jan 14. PubMed |
Chemical-defined and albumin-free generation of human atrial and ventricular myocytes from human pluripotent stem cells. Pei F, Jiang J, Bai S, Cao H, Tian L, Zhao Y, Yang C, Dong H, Ma Y. Stem Cell Res. 2017 Mar;19:94-103. doi: 10.1016/j.scr.2017.01.006. Epub 2017 Jan 12. PubMed |
Reprogramming Methods Do Not Affect Gene Expression Profile of Human Induced Pluripotent Stem Cells. Trevisan M, Desole G, Costanzi G, Lavezzo E, Palu G, Barzon L. Int J Mol Sci. 2017 Jan 20;18(1). pii: E206. doi: 10.3390/ijms18010206. PubMed |
Evaluation of porcine stem cell competence for somatic cell nuclear transfer and production of cloned animals. Secher JO, Liu Y, Petkov S, Luo Y, Li D, Hall VJ, Schmidt M, Callesen H, Bentzon JF, Sorensen CB, Freude KK, Hyttel P. Anim Reprod Sci. 2017 Mar;178:40-49. doi: 10.1016/j.anireprosci.2017.01.007. Epub 2017 Jan 19. PubMed |
Interspecies Chimerism with Mammalian Pluripotent Stem Cells. Wu J, Platero-Luengo A, Sakurai M, Sugawara A, Gil MA, Yamauchi T, Suzuki K, Bogliotti YS, Cuello C, Morales Valencia M, Okumura D, Luo J, Vilarino M, Parrilla I, Soto DA, Martinez CA, Hishida T, Sanchez-Bautista S, Martinez-Martinez ML, Wang H, Nohalez A, Aizawa E, Martinez-Redondo P, Ocampo A, Reddy P, Roca J, Maga EA, Esteban CR, Berggren WT, Nunez Delicado E, Lajara J, Guillen I, Guillen P, Campistol JM, Martinez EA, Ross PJ, Izpisua Belmonte JC. Cell. 2017 Jan 26;168(3):473-486.e15. doi: 10.1016/j.cell.2016.12.036. PubMed |
Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B. Zhang Y, Schmid B, Nikolaisen NK, Rasmussen MA, Aldana BI, Agger M, Calloe K, Stummann TC, Larsen HM, Nielsen TT, Huang J, Xu F, Liu X, Bolund L, Meyer M, Bak LK, Waagepetersen HS, Luo Y, Nielsen JE, Holst B, Clausen C, Hyttel P, Freude KK. Stem Cell Reports. 2017 Mar 14;8(3):648-658. doi: 10.1016/j.stemcr.2017.01.012. Epub 2017 Feb 16. PubMed |
Characterization of energy and neurotransmitter metabolism in cortical glutamatergic neurons derived from human induced pluripotent stem cells: A novel approach to study metabolism in human neurons. Aldana BI, Zhang Y, Lihme MF, Bak LK, Nielsen JE, Holst B, Hyttel P, Freude KK, Waagepetersen HS. Neurochem Int. 2017 Jun;106:48-61. doi: 10.1016/j.neuint.2017.02.010. Epub 2017 Feb 24. PubMed |
Rescue of the MERTK phagocytic defect in a human iPSC disease model using translational read-through inducing drugs. Ramsden CM, Nommiste B, R Lane A, Carr AF, Powner MB, J K Smart M, Chen LL, Muthiah MN, Webster AR, Moore AT, Cheetham ME, da Cruz L, Coffey PJ. Sci Rep. 2017 Mar 3;7(1):51. doi: 10.1038/s41598-017-00142-7. PubMed |
EIF4A3 deficient human iPSCs and mouse models demonstrate neural crest defects that underlie Richieri-Costa-Pereira syndrome. Miller EE, Kobayashi GS, Musso CM, Allen M, Ishiy FAA, de Caires LC Jr, Goulart E, Griesi-Oliveira K, Zechi-Ceide RM, Richieri-Costa A, Bertola DR, Passos-Bueno MR, Silver DL. Hum Mol Genet. 2017 Jun 15;26(12):2177-2191. doi: 10.1093/hmg/ddx078. PubMed |
Mutations in valosin-containing protein (VCP) decrease ADP/ATP translocation across the mitochondrial membrane and impair energy metabolism in human neurons. Ludtmann MHR, Arber C, Bartolome F, de Vicente M, Preza E, Carro E, Houlden H, Gandhi S, Wray S, Abramov AY. J Biol Chem. 2017 May 26;292(21):8907-8917. doi: 10.1074/jbc.M116.762898. Epub 2017 Mar 30. PubMed |
Establishment of MUi009 - A human induced pluripotent stem cells from a 32year old male with homozygous beta degrees -thalassemia coinherited with heterozygous alpha-thalassemia 2. Wongkummool W, Maneepitasut W, Tong-Ngam P, Tangprasittipap A, Munkongdee T, Boonchuay C, Svasti S, Kitiyanant N, Paiboonsukwong K, Fucharoen S, Tubsuwan A. Stem Cell Res. 2017 Apr;20:80-83. doi: 10.1016/j.scr.2017.02.012. Epub 2017 Mar 7. PubMed |
Derivation of the human induced pluripotent stem cell line MUi017-A from a patient with homozygous Hemoglobin Constant Spring. Wongkummool W, Maneepitasut W, Munkongdee T, Tong-Ngam P, Tangprasittipap A, Svasti S, Kitiyanant N, Paiboonsukwong K, Fucharoen S, Tubsuwan A. Stem Cell Res. 2017 Apr;20:84-87. doi: 10.1016/j.scr.2017.02.014. Epub 2017 Mar 7. PubMed |
Generation of induced pluripotent stem cells from peripheral blood CD34+ hematopoietic progenitors of a 31year old healthy woman. Tangprasittipap A, Jittorntrum B, Wongkummool W, Kitiyanant N, Tubsuwan A. Stem Cell Res. 2017 Apr;20:91-93. doi: 10.1016/j.scr.2017.02.013. Epub 2017 Mar 7. PubMed |
Generation of an induced pluripotent stem cell line from chorionic villi of a Turner syndrome spontaneous abortion. Parveen S, Panicker MM, Gupta PK. Stem Cell Res. 2017 Mar;19:12-16. doi: 10.1016/j.scr.2016.12.016. Epub 2016 Dec 13. PubMed |
Identification of SSEA-1 expressing enhanced reprogramming (SEER) cells in porcine embryonic fibroblasts. Li D, Secher JO, Juhl M, Mashayekhi K, Nielsen TT, Holst B, Hyttel P, Freude KK, Hall VJ. Cell Cycle. 2017 Jun 3;16(11):1070-1084. doi: 10.1080/15384101.2017.1315490. Epub 2017 Apr 20. PubMed |
Mitochondrial replacement in an iPSC model of Leber's hereditary optic neuropathy. Wong RCB, Lim SY, Hung SSC, Jackson S, Khan S, Van Bergen NJ, De Smit E, Liang HH, Kearns LS, Clarke L, Mackey DA, Hewitt AW, Trounce IA, Pebay A. Aging (Albany NY). 2017 Apr;9(4):1341-1350. doi: 10.18632/aging.101231. PubMed |
Fluorescent tagged episomals for stoichiometric induced pluripotent stem cell reprogramming.
Schmitt CE, Morales BM, Schmitz EMH, Hawkins JS, Lizama CO, Zape JP, Hsiao EC, Zovein AC.
Stem Cell Res Ther. 2017 Jun 5;8(1):132. doi: 10.1186/s13287-017-0581-7.
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Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols. Jeziorowska D, Fontaine V, Jouve C, Villard E, Dussaud S, Akbar D, Letang V, Cervello P, Itier JM, Pruniaux MP, Hulot JS. Int J Mol Sci. 2017 Jun 1;18(6). pii: E1173. doi: 10.3390/ijms18061173. PubMed |
Fetal Therapy Model of Myelomeningocele with Three-Dimensional Skin Using Amniotic Fluid Cell-Derived Induced Pluripotent Stem Cells. Kajiwara K, Tanemoto T, Wada S, Karibe J, Ihara N, Ikemoto Y, Kawasaki T, Oishi Y, Samura O, Okamura K, Takada S, Akutsu H, Sago H, Okamoto A, Umezawa A. Stem Cell Reports. 2017 Jun 6;8(6):1701-1713. doi: 10.1016/j.stemcr.2017.05.013. PubMed |
Generation of induced pluripotent stem cell (iPSC) line from a 36-year-old Charcot-Marie-Tooth disease patient with GJB1 mutation (CMTX). Son D, Kang PJ, Yun W, You S. Stem Cell Res. 2017 May;21:9-12. doi: 10.1016/j.scr.2017.03.006. Epub 2017 Mar 15. PubMed |
Static Magnetic Field Stimulation Enhances Oligodendrocyte Differentiation and Secretion of Neurotrophic Factors. Prasad A, Teh DBL, Blasiak A, Chai C, Wu Y, Gharibani PM, Yang IH, Phan TT, Lim KL, Yang H, Liu X, All AH. Sci Rep. 2017 Jul 27;7(1):6743. doi: 10.1038/s41598-017-06331-8. PubMed |
iPSC-derived neuronal models of PANK2-associated neurodegeneration reveal mitochondrial dysfunction contributing to early disease. Arber C, Angelova PR, Wiethoff S, Tsuchiya Y, Mazzacuva F, Preza E, Bhatia KP, Mills K, Gout I, Abramov AY, Hardy J, Duce JA, Houlden H, Wray S. PLoS One. 2017 Sep 1;12(9):e0184104. doi: 10.1371/journal.pone.0184104. eCollection 2017. PubMed |
Generation of an OCT4 reporter human induced pluripotent stem cell line using CRISPR/SpCas9.
Balboa D, Weltner J, Novik Y, Eurola S, Wartiovaara K, Otonkoski T.
Stem Cell Res. 2017 Aug;23:105-108. doi: 10.1016/j.scr.2017.07.006. Epub 2017 Jul 11.
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Generation of a SOX2 reporter human induced pluripotent stem cell line using CRISPR/SaCas9.
Balboa D, Weltner J, Novik Y, Eurola S, Wartiovaara K, Otonkoski T.
Stem Cell Res. 2017 Jul;22:16-19. doi: 10.1016/j.scr.2017.05.005. Epub 2017 May 17.
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Sodium channel current loss of function in induced pluripotent stem cell-derived cardiomyocytes from a Brugada syndrome patient. Selga E, Sendfeld F, Martinez-Moreno R, Medine CN, Tura-Ceide O, Wilmut SI, Perez GJ, Scornik FS, Brugada R, Mills NL. J Mol Cell Cardiol. 2018 Jan;114:10-19. doi: 10.1016/j.yjmcc.2017.10.002. Epub 2017 Oct 9. PubMed |
Generation of induced pluripotent stem cell (iPSC) line from Charcot-Marie-Tooth disease patient with MPZ mutation (CMT1B). Son D, Kang PJ, Yun W, You S. Stem Cell Res. 2017 Oct;24:5-7. doi: 10.1016/j.scr.2017.08.002. Epub 2017 Aug 5. PubMed |
Down Syndrome iPSC-Derived Astrocytes Impair Neuronal Synaptogenesis and the mTOR Pathway In Vitro. Araujo BHS, Kaid C, De Souza JS, Gomes da Silva S, Goulart E, Caires LCJ, Musso CM, Torres LB, Ferrasa A, Herai R, Zatz M, Okamoto OK, Cavalheiro EA. Mol Neurobiol. 2017 Nov 11. pii: 10.1007/s12035-017-0818-6. doi: 10.1007/s12035-017-0818-6. PubMed |
TALEN-mediated shift of mitochondrial DNA heteroplasmy in MELAS-iPSCs with m.13513G>A mutation. Yahata N, Matsumoto Y, Omi M, Yamamoto N, Hata R. Sci Rep. 2017 Nov 14;7(1):15557. doi: 10.1038/s41598-017-15871-y. PubMed |
Establishment and characterization of induced pluripotent stem cells from placental mesenchymal stromal cells. Parveen S. Stem Cell Res. 2018 Mar;27:15-20. doi: 10.1016/j.scr.2017.12.008. Epub 2017 Dec 14. PubMed |
Generation of induced pluripotent stem cell line, CSSi002-A (2851), from a patient with juvenile Huntington Disease. Rosati J, Bidollari E, Rotundo G, Ferrari D, Torres B, Bernardini L, Consoli F, De Luca A, Santimone I, Lamorte G, Squitieri F, Vescovi AL. Stem Cell Res. 2018 Mar;27:86-89. doi: 10.1016/j.scr.2018.01.011. Epub 2018 Jan 9. PubMed |
Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells. Caires-Junior LC, Goulart E, Melo US, Araujo BHS, Alvizi L, Soares-Schanoski A, de Oliveira DF, Kobayashi GS, Griesi-Oliveira K, Musso CM, Amaral MS, daSilva LF, Astray RM, Suarez-Patino SF, Ventini DC, Gomes da Silva S, Yamamoto GL, Ezquina S, Naslavsky MS, Telles-Silva KA, Weinmann K, van der Linden V, van der Linden H, de Oliveira JRM, Arrais NMR, Melo A, Figueiredo T, Santos S, Meira JGC, Passos SD, de Almeida RP, Bispo AJB, Cavalheiro EA, Kalil J, Cunha-Neto E, Nakaya H, Andreata-Santos R, de Souza Ferreira LC, Verjovski-Almeida S, Ho PL, Passos-Bueno MR, Zatz M. Nat Commun. 2018 Feb 2;9(1):475. doi: 10.1038/s41467-017-02790-9. PubMed |
Oxidative stress and altered mitochondrial protein expression in the absence of amyloid-beta and tau pathology in iPSC-derived neurons from sporadic Alzheimer's disease patients. Birnbaum JH, Wanner D, Gietl AF, Saake A, Kundig TM, Hock C, Nitsch RM, Tackenberg C. Stem Cell Res. 2018 Mar;27:121-130. doi: 10.1016/j.scr.2018.01.019. Epub 2018 Jan 28. PubMed |
Induced pluripotent stem cells line (UNIPDi003-A) from a patient affected by EEC syndrome carrying the R279H mutation in TP63 gene. Trevisan M, Di Iorio E, Masi G, Riccetti S, Barzon L, Alvisi G, Caenazzo L, Barbaro V, Palu G. Stem Cell Res. 2018 Apr;28:141-144. doi: 10.1016/j.scr.2018.02.008. Epub 2018 Feb 16. PubMed |
Generation of induced pluripotent stem cell line, CSSi004-A (2962), from a patient diagnosed with Huntington's disease at the presymptomatic stage. Bidollari E, Rotundo G, Ferrari D, Candido O, Bernardini L, Consoli F, De Luca A, Santimone I, Lamorte G, Ilari A, Squitieri F, Vescovi AL, Rosati J. Stem Cell Res. 2018 Apr;28:145-148. doi: 10.1016/j.scr.2018.02.014. Epub 2018 Feb 21. PubMed |
Generation of a transgene-free human induced pluripotent stem cell line (UNIPDi001-A) from oral mucosa epithelial stem cells. Alvisi G, Trevisan M, Masi G, Canel V, Caenazzo L, Nespeca P, Barzon L, Di Iorio E, Barbaro V, Palu G. Stem Cell Res. 2018 Apr;28:177-180. doi: 10.1016/j.scr.2018.02.007. Epub 2018 Feb 18. PubMed |
Amenable epigenetic traits of dental pulp stem cells underlie high capability of xeno-free episomal reprogramming. Thekkeparambil Chandrabose S, Sriram S, Subramanian S, Cheng S, Ong WK, Rozen S, Kasim NHA, Sugii S. Stem Cell Res Ther. 2018 Mar 20;9(1):68. doi: 10.1186/s13287-018-0796-2. PubMed |
Direct evidence of impaired neuronal Na/K-ATPase pump function in alternating hemiplegia of childhood. Simmons CQ, Thompson CH, Cawthon BE, Westlake G, Swoboda KJ, Kiskinis E, Ess KC, George AL Jr. Neurobiol Dis. 2018 Jul;115:29-38. doi: 10.1016/j.nbd.2018.03.009. Epub 2018 Mar 19. PubMed |
Mutations in PMPCB Encoding the Catalytic Subunit of the Mitochondrial Presequence Protease Cause Neurodegeneration in Early Childhood. Vogtle FN, Brandl B, Larson A, Pendziwiat M, Friederich MW, White SM, Basinger A, Kucukkose C, Muhle H, Jahn JA, Keminer O, Helbig KL, Delto CF, Myketin L, Mossmann D, Burger N, Miyake N, Burnett A, van Baalen A, Lovell MA, Matsumoto N, Walsh M, Yu HC, Shinde DN, Stephani U, Van Hove JLK, Muller FJ, Helbig I. Am J Hum Genet. 2018 Apr 5;102(4):557-573. doi: 10.1016/j.ajhg.2018.02.014. Epub 2018 Mar 22. PubMed |
Comparison of two different culture conditions for derivation of early hiPSC. Hey CAB, Saltokova KB, Bisgaard HC, Moller LB. Cell Biol Int. 2018 Nov;42(11):1467-1473. doi: 10.1002/cbin.10966. Epub 2018 May 10. PubMed |
Generation of an integration-free iPSC line (CSCRi005-A) from erythroid progenitor cells of a healthy Indian male individual. Manian KV, Bharathan SP, Maddali M, Srivastava VM, Srivastava A, Velayudhan SR. Stem Cell Res. 2018 May;29:148-151. doi: 10.1016/j.scr.2018.03.020. Epub 2018 Apr 3. PubMed |
Generation of the induced pluripotent stem cell line CSSi006-A (3681) from a patient affected by advanced-stage Juvenile Onset Huntington's Disease. Rotundo G, Bidollari E, Ferrari D, Spasari I, Bernardini L, Consoli F, De Luca A, Santimone I, Lamorte G, Migliore S, Squitieri F, Vescovi AL, Rosati J. Stem Cell Res. 2018 May;29:174-178. doi: 10.1016/j.scr.2018.04.008. Epub 2018 Apr 21. PubMed |
Developing two reference control samples for the Indian population. Iyer S, Bhatia P, Rao M, Mukherjee O. Stem Cell Res. 2018 Jul;30:38-42. doi: 10.1016/j.scr.2018.05.001. Epub 2018 May 12. PubMed |
High Basal Levels of gammaH2AX in Human Induced Pluripotent Stem Cells Are Linked to Replication-Associated DNA Damage and Repair. Vallabhaneni H, Lynch PJ, Chen G, Park K, Liu Y, Goehe R, Mallon BS, Boehm M, Hursh DA. Stem Cells. 2018 Oct;36(10):1501-1513. doi: 10.1002/stem.2861. Epub 2018 Jul 28. PubMed |
Human pluripotent reprogramming with CRISPR activators.
Weltner J, Balboa D, Katayama S, Bespalov M, Krjutskov K, Jouhilahti EM, Trokovic R, Kere J, Otonkoski T.
Nat Commun. 2018 Jul 6;9(1):2643. doi: 10.1038/s41467-018-05067-x.
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Oral Mucosa-Derived Induced Pluripotent Stem Cells from Patients with Ectrodactyly-Ectodermal Dysplasia-Clefting Syndrome. Trevisan M, Alvisi G, Barbaro V, Barzon L, Raffa P, Migliorati A, Desole G, Ruzittu S, Masi G, Di Iorio E, Palu G. Cell Reprogram. 2018 Aug;20(4):215-224. doi: 10.1089/cell.2017.0064. Epub 2018 Jul 10. PubMed |
A fast method to reprogram and CRISPR/Cas9 gene editing from erythroblasts. Melo US, de Souza Leite F, Costa S, Rosenberg C, Zatz M. Stem Cell Res. 2018 Aug;31:52-54. doi: 10.1016/j.scr.2018.07.002. Epub 2018 Jul 4. PubMed |
GFAP Mutations in Astrocytes Impair Oligodendrocyte Progenitor Proliferation and Myelination in an hiPSC Model of Alexander Disease. Li L, Tian E, Chen X, Chao J, Klein J, Qu Q, Sun G, Sun G, Huang Y, Warden CD, Ye P, Feng L, Li X, Cui Q, Sultan A, Douvaras P, Fossati V, Sanjana NE, Riggs AD, Shi Y. Cell Stem Cell. 2018 Aug 2;23(2):239-251.e6. doi: 10.1016/j.stem.2018.07.009. PubMed |
Directed evolution of CRISPR-Cas9 to increase its specificity.
Lee JK, Jeong E, Lee J, Jung M, Shin E, Kim YH, Lee K, Jung I, Kim D, Kim S, Kim JS.
Nat Commun. 2018 Aug 6;9(1):3048. doi: 10.1038/s41467-018-05477-x.
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Generation of three spinocerebellar ataxia type-12 patients derived induced pluripotent stem cell lines (IGIBi002-A, IGIBi003-A and IGIBi004-A). Kumar D, Hussain A, Srivastava AK, Mukerji M, Mukherjee O, Faruq M. Stem Cell Res. 2018 Aug;31:216-221. doi: 10.1016/j.scr.2018.08.008. Epub 2018 Aug 14. PubMed |
Generation of induced pluripotent stem cells, KCi001-A derived from a Bardet-Biedl syndrome patient compound heterozygous for the BBS1 variants c.1169T>G/c.1135G>C. Hey CAB, Saltokowa KB, Larsen LJ, Tumer Z, Brondum-Nielsen K, Gronskov K, Hjortshoj TD, Moller LB. Stem Cell Res. 2018 Aug;31:235-239. doi: 10.1016/j.scr.2018.08.005. Epub 2018 Aug 10. PubMed |
The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans. Xiang X, Piers TM, Wefers B, Zhu K, Mallach A, Brunner B, Kleinberger G, Song W, Colonna M, Herms J, Wurst W, Pocock JM, Haass C. Mol Neurodegener. 2018 Sep 6;13(1):49. doi: 10.1186/s13024-018-0280-6. PubMed |
Establishment of stable iPS-derived human neural stem cell lines suitable for cell therapies. Rosati J, Ferrari D, Altieri F, Tardivo S, Ricciolini C, Fusilli C, Zalfa C, Profico DC, Pinos F, Bernardini L, Torres B, Manni I, Piaggio G, Binda E, Copetti M, Lamorte G, Mazza T, Carella M, Gelati M, Valente EM, Simeone A, Vescovi AL. Cell Death Dis. 2018 Sep 17;9(10):937. doi: 10.1038/s41419-018-0990-2. PubMed |
Standards for Deriving Nonhuman Primate-Induced Pluripotent Stem Cells, Neural Stem Cells and Dopaminergic Lineage. Yang G, Hong H, Torres A, Malloy KE, Choudhury GR, Kim J, Daadi MM. Int J Mol Sci. 2018 Sep 17;19(9). pii: ijms19092788. doi: 10.3390/ijms19092788. PubMed |
Single-cell RNA-seq reveals dynamic transcriptome profiling in human early neural differentiation. Shang Z, Chen D, Wang Q, Wang S, Deng Q, Wu L, Liu C, Ding X, Wang S, Zhong J, Zhang D, Cai X, Zhu S, Yang H, Liu L, Fink JL, Chen F, Liu X, Gao Z, Xu X. Gigascience. 2018 Nov 1;7(11). pii: 5099469. doi: 10.1093/gigascience/giy117. PubMed |
Generation of integration-free iPS cell lines from three sickle cell disease patients from the state of Bahia, Brazil. Martins GLS, Paredes BD, Azevedo CM, Sampaio GLA, Nonaka CKV, Cavalcante BRR, Da Silva KN, Pereira CSE, Soares MBP, Dos Santos RR, Souza BSF. Stem Cell Res. 2018 Dec;33:10-14. doi: 10.1016/j.scr.2018.09.011. Epub 2018 Sep 25. PubMed |
Generation of an iPSC line of a patient with Angelman syndrome due to an imprinting defect. Neureiter A, Brandl B, Hiber M, Tandon R, Muller FJ, Steenpass L. Stem Cell Res. 2018 Dec;33:20-24. doi: 10.1016/j.scr.2018.09.015. Epub 2018 Sep 24. PubMed |
Generation of induced pluripotent stem cells, KCi002-A derived from a patient with Bardet-Biedl syndrome homozygous for the BBS10 variant c.271insT. Hey CAB, Saltokowa KB, Larsen LJ, Tumer Z, Brondum-Nielsen K, Gronskov K, Hjortshoj TD, Moller LB. Stem Cell Res. 2018 Dec;33:46-50. doi: 10.1016/j.scr.2018.09.013. Epub 2018 Sep 20. PubMed |
The 7q11.23 Protein DNAJC30 Interacts with ATP Synthase and Links Mitochondria to Brain Development. Tebbenkamp ATN, Varela L, Choi J, Paredes MI, Giani AM, Song JE, Sestan-Pesa M, Franjic D, Sousa AMM, Liu ZW, Li M, Bichsel C, Koch M, Szigeti-Buck K, Liu F, Li Z, Kawasawa YI, Paspalas CD, Mineur YS, Prontera P, Merla G, Picciotto MR, Arnsten AFT, Horvath TL, Sestan N. Cell. 2018 Nov 1;175(4):1088-1104.e23. doi: 10.1016/j.cell.2018.09.014. PubMed |
Generating Loss-of-function iPSC Lines with Combined CRISPR Indel Formation and Reprogramming from Human Fibroblasts. Tidball AM, Swaminathan P, Dang LT, Parent JM. Bio Protoc. 2018 Apr 5;8(7). doi: 10.21769/BioProtoc.2794. PubMed |
Generation of two human isogenic iPSC lines from fetal dermal fibroblasts. Tandon R, Brandl B, Baryshnikova N, Landshammer A, Steenpass L, Keminer O, Pless O, Muller FJ. Stem Cell Res. 2018 Dec;33:120-124. doi: 10.1016/j.scr.2018.10.004. Epub 2018 Oct 12. PubMed |
Integrated generation of induced pluripotent stem cells in a low-cost device. Lin H, Li Q, Du Q, Wang O, Wang Z, Akert L, Carlson MA, Zhang C, Subramanian A, Zhang C, Lunning M, Li M, Lei Y. Biomaterials. 2019 Jan;189:23-36. doi: 10.1016/j.biomaterials.2018.10.027. Epub 2018 Oct 25. PubMed |
Cardiac Targeting Peptide, a Novel Cardiac Vector: Studies in Bio-Distribution, Imaging Application, and Mechanism of Transduction. Zahid M, Feldman KS, Garcia-Borrero G, Feinstein TN, Pogodzinski N, Xu X, Yurko R, Czachowski M, Wu YL, Mason NS, Lo CW. Biomolecules. 2018 Nov 14;8(4). pii: biom8040147. doi: 10.3390/biom8040147. PubMed |
Optimization of episomal reprogramming for generation of human induced pluripotent stem cells from fibroblasts. Bang JS, Choi NY, Lee M, Ko K, Lee HJ, Park YS, Jeong D, Chung HM, Ko K. Anim Cells Syst (Seoul). 2018 Mar 15;22(2):132-139. doi: 10.1080/19768354.2018.1451367. eCollection 2018. PubMed |
Mbd3 Promotes Reprogramming of Primary Human Fibroblasts. Jaffer S, Goh P, Abbasian M, Nathwani AC. Int J Stem Cells. 2018 Nov 30;11(2):235-241. doi: 10.15283/ijsc18036. PubMed |
MicroRNA characterization in equine induced pluripotent stem cells. Moro LN, Amin G, Furmento V, Waisman A, Garate X, Neiman G, La Greca A, Santin Velazque NL, Luzzani C, Sevlever GE, Vichera G, Miriuka SG. PLoS One. 2018 Dec 3;13(12):e0207074. doi: 10.1371/journal.pone.0207074. eCollection 2018. PubMed |
Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing. Lo Sardo V, Chubukov P, Ferguson W, Kumar A, Teng EL, Duran M, Zhang L, Cost G, Engler AJ, Urnov F, Topol EJ, Torkamani A, Baldwin KK. Cell. 2018 Dec 13;175(7):1796-1810.e20. doi: 10.1016/j.cell.2018.11.014. Epub 2018 Dec 6. PubMed |
Plasmid-based generation of neural cells from human fibroblasts using non-integrating episomal vectors. Dai SB, Shen T, Zheng TT, Pu JL, Chen XZ. Neural Regen Res. 2019 Mar;14(3):501-505. doi: 10.4103/1673-5374.245476. PubMed |
Derivation of iPSC lines from two patients with familial Alzheimer's disease from India. Najar AH, Sneha KM, Ashok A, Babu S, Subramaniam AG, Kannan R, Viswanath B, Purushottam M, Varghese M, Parvez S, Panicker MM, Mukherjee O, Jain S. Stem Cell Res. 2019 Jan;34:101370. doi: 10.1016/j.scr.2018.101370. Epub 2018 Dec 19. PubMed |
Generation of seven induced pluripotent stem cell lines from neonates of different ethnic backgrounds. Yin Y, Petersen AJ, Soref C, Richards WD, Ludwig T, Taapken S, Berndt E, Zhang SC, Bhattacharyya A. Stem Cell Res. 2019 Jan;34:101365. doi: 10.1016/j.scr.2018.101365. Epub 2018 Dec 20. PubMed |
DNA damage and transcriptional regulation in iPSC-derived neurons from Ataxia Telangiectasia patients. Corti A, Sota R, Dugo M, Calogero RA, Terragni B, Mantegazza M, Franceschetti S, Restelli M, Gasparini P, Lecis D, Chrzanowska KH, Delia D. Sci Rep. 2019 Jan 24;9(1):651. doi: 10.1038/s41598-018-36912-0. PubMed |
SMCHD1 is involved in de novo methylation of the DUX4-encoding D4Z4 macrosatellite. Dion C, Roche S, Laberthonniere C, Broucqsault N, Mariot V, Xue S, Gurzau AD, Nowak A, Gordon CT, Gaillard MC, El-Yazidi C, Thomas M, Schlupp-Robaglia A, Missirian C, Malan V, Ratbi L, Sefiani A, Wollnik B, Binetruy B, Salort Campana E, Attarian S, Bernard R, Nguyen K, Amiel J, Dumonceaux J, Murphy JM, Dejardin J, Blewitt ME, Reversade B, Robin JD, Magdinier F. Nucleic Acids Res. 2019 Apr 8;47(6):2822-2839. doi: 10.1093/nar/gkz005. PubMed |
Distinct pathological signatures in human cellular models of myotonic dystrophy subtypes. Kim EY, Barefield DY, Vo AH, Gacita AM, Schuster EJ, Wyatt EJ, Davis JL, Dong B, Sun C, Page P, Dellefave-Castillo L, Demonbreun A, Zhang HF, McNally EM. JCI Insight. 2019 Mar 21;4(6). pii: 122686. doi: 10.1172/jci.insight.122686. eCollection 2019 Mar 21. PubMed |
Neutrophils Derived from Genetically Modified Human Induced Pluripotent Stem Cells Circulate and Phagocytose Bacteria In Vivo. Trump LR, Nayak RC, Singh AK, Emberesh S, Wellendorf AM, Lutzko CM, Cancelas JA. Stem Cells Transl Med. 2019 Jun;8(6):557-567. doi: 10.1002/sctm.18-0255. Epub 2019 Feb 21. PubMed |
Generation of a human induced pluripotent stem cell line (MUi010-A) from skin fibroblast of patient carrying a c.2104C>T mutation in MYH9 gene. Tangprasittipap A, Jittorntrum B, Kadegasem P, Sasanakul W, Sirachainan N, Kitiyanant N, Hongeng S. Stem Cell Res. 2019 Apr;36:101397. doi: 10.1016/j.scr.2019.101397. Epub 2019 Feb 18. PubMed |
Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming. Ebrahimi A, Sevinc K, Gurhan Sevinc G, Cribbs AP, Philpott M, Uyulur F, Morova T, Dunford JE, Goklemez S, Ari S, Oppermann U, Onder TT. Nat Chem Biol. 2019 May;15(5):519-528. doi: 10.1038/s41589-019-0264-z. Epub 2019 Apr 8. PubMed |
Familial Alzheimer's disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta. Arber C, Toombs J, Lovejoy C, Ryan NS, Paterson RW, Willumsen N, Gkanatsiou E, Portelius E, Blennow K, Heslegrave A, Schott JM, Hardy J, Lashley T, Fox NC, Zetterberg H, Wray S. Mol Psychiatry. 2019 Apr 12. pii: 10.1038/s41380-019-0410-8. doi: 10.1038/s41380-019-0410-8. PubMed |
Evaluation of commonly used ectoderm markers in iPSC trilineage differentiation. Kuang YL, Munoz A, Nalula G, Santostefano KE, Sanghez V, Sanchez G, Terada N, Mattis AN, Iacovino M, Iribarren C, Krauss RM, Medina MW. Stem Cell Res. 2019 May;37:101434. doi: 10.1016/j.scr.2019.101434. Epub 2019 Apr 10. PubMed |
Generation of three control iPS cell lines for sickle cell disease studies by reprogramming erythroblasts from individuals without hemoglobinopathies. Paredes BD, Martins GLS, Azevedo CM, Sampaio GLA, Nonaka CKV, Silva KND, Soares MBP, Santos RRD, Souza BSF. Stem Cell Res. 2019 Jul;38:101454. doi: 10.1016/j.scr.2019.101454. Epub 2019 May 4. PubMed |
Environmental stress impairs photoreceptor outer segment (POS) phagocytosis and degradation and induces autofluorescent material accumulation in hiPSC-RPE cells. Dalvi S, Galloway CA, Winschel L, Hashim A, Soto C, Tang C, MacDonald LA, Singh R. Cell Death Discov. 2019 May 16;5:96. doi: 10.1038/s41420-019-0171-9. eCollection 2019. PubMed |
The Effect of Wnt Pathway Modulators on Human iPSC-Derived Pancreatic Beta Cell Maturation. Vethe H, Ghila L, Berle M, Hoareau L, Haaland OA, Scholz H, Paulo JA, Chera S, Raeder H. Front Endocrinol (Lausanne). 2019 May 8;10:293. doi: 10.3389/fendo.2019.00293. eCollection 2019. PubMed |
Feasibility of repairing full-thickness skin defects by iPSC-derived epithelial stem cells seeded on a human acellular amniotic membrane. Zhou H, Wang L, Zhang C, Hu J, Chen J, Du W, Liu F, Ren W, Wang J, Quan R. Stem Cell Res Ther. 2019 May 31;10(1):155. doi: 10.1186/s13287-019-1234-9. PubMed |
Ex Vivo Models of Chronic Granulomatous Disease. Brault J, Vigne B, Stasia MJ. Methods Mol Biol. 2019;1982:587-622. doi: 10.1007/978-1-4939-9424-3_35. PubMed |
Embryonic Chimeras with Human Pluripotent Stem Cells. De Los Angeles A, Sakurai M, Wu J. Methods Mol Biol. 2019;2005:125-151. doi: 10.1007/978-1-4939-9524-0_9. PubMed |
Parkin Mutation Affects Clock Gene-Dependent Energy Metabolism. Pacelli C, Rotundo G, Lecce L, Menga M, Bidollari E, Scrima R, Cela O, Piccoli C, Cocco T, Vescovi AL, Mazzoccoli G, Rosati J, Capitanio N. Int J Mol Sci. 2019 Jun 5;20(11). pii: ijms20112772. doi: 10.3390/ijms20112772. PubMed |
Production and characterization of human induced pluripotent stem cells (iPSC) CSSi007-A (4383) from Joubert Syndrome. Altieri F, D'Anzi A, Martello F, Tardivo S, Spasari I, Ferrari D, Bernardini L, Lamorte G, Mazzoccoli G, Valente EM, Vescovi AL, Rosati J. Stem Cell Res. 2019 Jul;38:101480. doi: 10.1016/j.scr.2019.101480. Epub 2019 Jun 5. PubMed |
A six-inhibitor culture medium for improving naive-type pluripotency of porcine pluripotent stem cells. Yuan Y, Park J, Tian Y, Choi J, Pasquariello R, Alexenko AP, Dai A, Behura SK, Roberts RM, Ezashi T. Cell Death Discov. 2019 Jun 17;5:104. doi: 10.1038/s41420-019-0184-4. eCollection 2019. PubMed |
Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network. Low JH, Li P, Chew EGY, Zhou B, Suzuki K, Zhang T, Lian MM, Liu M, Aizawa E, Rodriguez Esteban C, Yong KSM, Chen Q, Campistol JM, Fang M, Khor CC, Foo JN, Izpisua Belmonte JC, Xia Y. Cell Stem Cell. 2019 Sep 5;25(3):373-387.e9. doi: 10.1016/j.stem.2019.06.009. Epub 2019 Jul 11. PubMed |
Directed differentiation of human induced pluripotent stem cells into mature stratified bladder urothelium. Suzuki K, Koyanagi-Aoi M, Uehara K, Hinata N, Fujisawa M, Aoi T. Sci Rep. 2019 Jul 19;9(1):10506. doi: 10.1038/s41598-019-46848-8. PubMed |
Generation of two induced pluripotent stem cell (iPSC) lines from human breast milk using episomal reprogramming system. Tang C, Lu C, Ji X, Ma L, Zhou Q, Xiong M, Zhou W. Stem Cell Res. 2019 Aug;39:101511. doi: 10.1016/j.scr.2019.101511. Epub 2019 Jul 27. PubMed |
Generation of induced pluripotent stem cell line CSSi008-A (4698) from a patient affected by advanced stage of Dentato-Rubral-Pallidoluysian atrophy (DRPLA). Bidollari E, Rotundo G, Altieri F, Amicucci M, Wiquel D, Ferrari D, Goldoni M, Bernardini L, Consoli F, De Luca A, Fanelli S, Lamorte G, D'Agruma L, Vescovi AL, Squitieri F, Rosati J. Stem Cell Res. 2019 Oct;40:101551. doi: 10.1016/j.scr.2019.101551. Epub 2019 Aug 27. PubMed |
Tracking and Predicting Human Somatic Cell Reprogramming Using Nuclear Characteristics. Molugu K, Harkness T, Carlson-Stevermer J, Prestil R, Piscopo NJ, Seymour SK, Knight GT, Ashton RS, Saha K. Biophys J. 2019 Oct 22. pii: S0006-3495(19)30862-8. doi: 10.1016/j.bpj.2019.10.014. PubMed |
Generation of human iPS cell line CBTCi001-A from dermal fibroblasts obtained from a healthy donor. Martins GLS, Paredes BD, Sampaio GLA, Nonaka CKV, da Silva KN, Allahdadi KJ, Franca LSA, Soares MBP, Dos Santos RR, Souza BSF. Stem Cell Res. 2019 Dec;41:101630. doi: 10.1016/j.scr.2019.101630. Epub 2019 Oct 21. PubMed |
Generation and characterization of three isogenic induced pluripotent stem cell lines from a patient with Bardet-Biedl syndrome and homozygous for the BBS5 variant. Hey CAB, Larsen LJ, Tumer Z, Brondum-Nielsen K, Gronskov K, Hjortshoj TD, Moller LB. Stem Cell Res. 2019 Dec;41:101594. doi: 10.1016/j.scr.2019.101594. Epub 2019 Nov 4. PubMed |
Advances in Pluripotent Stem Cells: History, Mechanisms, Technologies, and Applications. Liu G, David BT, Trawczynski M, Fessler RG. Stem Cell Rev Rep. 2020 Feb;16(1):3-32. doi: 10.1007/s12015-019-09935-x. PubMed |
Generation of eight human induced pluripotent stem cell lines from Parkinson's disease patients carrying familial mutations. Chen M, Maimaitili M, Buchholdt SH, Jensen UB, Febbraro F, Denham M. Stem Cell Res. 2020 Jan;42:101657. doi: 10.1016/j.scr.2019.101657. Epub 2019 Nov 13. PubMed |
Reprogrammed Cells Display Distinct Proteomic Signatures Associated with Colony Morphology Variability. Bjorlykke Y, Soviknes AM, Hoareau L, Vethe H, Mathisen AF, Chera S, Vaudel M, Ghila LM, Raeder H. Stem Cells Int. 2019 Nov 18;2019:8036035. doi: 10.1155/2019/8036035. eCollection 2019. PubMed |
A locked immunometabolic switch underlies TREM2 R47H loss of function in human iPSC-derived microglia. Piers TM, Cosker K, Mallach A, Johnson GT, Guerreiro R, Hardy J, Pocock JM. FASEB J. 2020 Feb;34(2):2436-2450. doi: 10.1096/fj.201902447R. Epub 2019 Dec 23. PubMed |
Screening ToxCast for Chemicals That Affect Cholesterol Biosynthesis: Studies in Cell Culture and Human Induced Pluripotent Stem Cell-Derived Neuroprogenitors. Wages PA, Joshi P, Tallman KA, Kim HH, Bowman AB, Porter NA. Environ Health Perspect. 2020 Jan;128(1):17014. doi: 10.1289/EHP5053. Epub 2020 Jan 27. PubMed |
Generation and characterization of a human iPSC line derived from congenital clubfoot amniotic fluid cells. Wang J, Cui Y, Xing K, Luan J, Han J. Stem Cell Res. 2020 Mar;43:101712. doi: 10.1016/j.scr.2020.101712. Epub 2020 Jan 17. PubMed |
Generation of human induced pluripotent stem cell line (WMUi001-A) from a patient with aortic dissection. Jin P, Wang S, Jiang X, Shan X, Jiang S, Quan Y, Zhang T, Yang J, Zhang H, Ma J, Dong M, Fan J, Fan X, Gong Y, Wang Y. Stem Cell Res. 2020 Mar;43:101730. doi: 10.1016/j.scr.2020.101730. Epub 2020 Feb 6. PubMed |
Chromosome 19 microRNA cluster enhances cell reprogramming by inhibiting epithelial-to-mesenchymal transition. Mong EF, Yang Y, Akat KM, Canfield J, VanWye J, Lockhart J, Tsibris JCM, Schatz F, Lockwood CJ, Tuschl T, Kayisli UA, Totary-Jain H. Sci Rep. 2020 Feb 20;10(1):3029. doi: 10.1038/s41598-020-59812-8. PubMed |
Modeling of early neural development in vitro by direct neurosphere formation culture of chimpanzee induced pluripotent stem cells. Kitajima R, Nakai R, Imamura T, Kameda T, Kozuka D, Hirai H, Ito H, Imai H, Imamura M. Stem Cell Res. 2020 Apr;44:101749. doi: 10.1016/j.scr.2020.101749. Epub 2020 Feb 28. PubMed |
In vivo Environment Swiftly Restricts Human Pancreatic Progenitors Toward Mono-Hormonal Identity via a HNF1A/HNF4A Mechanism. Legoy TA, Mathisen AF, Salim Z, Vethe H, Bjorlykke Y, Abadpour S, Paulo JA, Scholz H, Raeder H, Ghila L, Chera S. Front Cell Dev Biol. 2020 Feb 25;8:109. doi: 10.3389/fcell.2020.00109. eCollection 2020. PubMed |
Establishment of an iPSC line (JTUi002-A) from a patient with Waardenburg syndrome caused by a SOX10 mutation and carrying a GJB2 mutation. Wang P, Wang J, Xing Y, Wang H, Yu D, Feng Y, Wu H, Wu Y, Chen Z, Wang J, Shi H. Stem Cell Res. 2020 Apr;44:101756. doi: 10.1016/j.scr.2020.101756. Epub 2020 Mar 7. PubMed |
Human Adipose-Derived Pericytes: Biological Characterization and Reprogramming into Induced Pluripotent Stem Cells. Ahmed TA, Shousha WG, Abdo SM, Mohamed IK, El-Badri N. Cell Physiol Biochem. 2020 Apr 1;54(2):271-286. doi: 10.33594/000000219. PubMed |
Establishment of an induced pluripotent stem cell line from a patient with CHARGE syndrome carrying a CHD7 (p.L1151Gfs*17) mutation. He S, Hu J, Zheng Z, Wang J, Chen J, Zhang C, Li L, Wang J, Chen Z, Shi H, Wang J. Stem Cell Res. 2020 May;45:101774. doi: 10.1016/j.scr.2020.101774. Epub 2020 Mar 20. PubMed |
Derivation of three induced pluripotent stem cell lines under feeder-free culture conditions from peripheral blood mononuclear cells (PBMC) of Indian patients suffering from inherited retinal diseases carrying different mutations. Konala VBR, Nandakumar S, Battu R, Pal R. Stem Cell Res. 2020 May;45:101757. doi: 10.1016/j.scr.2020.101757. Epub 2020 Mar 20. PubMed |
Generation of iPSC-lines from two independent Takotsubo syndrome patients with recurrent Takotsubo events. Hubscher D, Rebs S, Maurer W, Ghadri JR, Dressel R, Templin C, Streckfuss-Bomeke K. Stem Cell Res. 2020 Apr;44:101746. doi: 10.1016/j.scr.2020.101746. Epub 2020 Feb 24. PubMed |
Neuronal modeling of alternating hemiplegia of childhood reveals transcriptional compensation and replicates a trigger-induced phenotype. Snow JP, Westlake G, Klofas LK, Jeon S, Armstrong LC, Swoboda KJ, George AL Jr, Ess KC. Neurobiol Dis. 2020 Jul;141:104881. doi: 10.1016/j.nbd.2020.104881. Epub 2020 Apr 27. PubMed |
Generation and characterization of HLA-universal platelets derived from induced pluripotent stem cells. Norbnop P, Ingrungruanglert P, Israsena N, Suphapeetiporn K, Shotelersuk V. Sci Rep. 2020 May 21;10(1):8472. doi: 10.1038/s41598-020-65577-x. PubMed |
Generation of four postmortem dura-derived iPS cell lines from four control individuals with genotypic and brain-region-specific transcriptomic data available through the BrainSEQ consortium. Sawada T, Benjamin KJM, Brandtjen AC, Tietze E, Allen SJ, Paquola ACM, Kleinman JE, Hyde TM, Erwin JA. Stem Cell Res. 2020 Jul;46:101806. doi: 10.1016/j.scr.2020.101806. Epub 2020 Apr 20. PubMed |
Generation of human induced pluripotent stem cells (SDUKIi002-A) from a 22-year-old male diagnosed with autism spectrum disorder. Kamand M, Ilieva M, Forsberg SL, Thomassen M, Fex Svenningsen A, Holst B, Meyer M, Michel TM. Stem Cell Res. 2020 Jul;46:101834. doi: 10.1016/j.scr.2020.101834. Epub 2020 May 7. PubMed |
Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936. Toombs J, Panther L, Ornelas L, Liu C, Gomez E, Martin-Ibanez R, Cox SR, Ritchie SJ, Harris SE, Taylor A, Redmond P, Russ TC, Murphy L, Cooper JD, Burr K, Selvaraj BT, Browne C, Svendsen CN, Cowley SA, Deary IJ, Chandran S, Spires-Jones TL, Sareen D. Stem Cell Res. 2020 Jul;46:101851. doi: 10.1016/j.scr.2020.101851. Epub 2020 May 20. PubMed |
Multimodal Analysis of STRADA Function in Brain Development. Dang LT, Glanowska KM, Iffland Ii PH, Barnes AE, Baybis M, Liu Y, Patino G, Vaid S, Streicher AM, Parker WE, Kim S, Moon UY, Henry FE, Murphy GG, Sutton M, Parent JM, Crino PB. Front Cell Neurosci. 2020 May 8;14:122. doi: 10.3389/fncel.2020.00122. eCollection 2020. PubMed |
Characterization of an induced pluripotent stem cell line (IMBPASi001-A) derived from fibroblasts of a patient affected by Wolfram Syndrome. Grzela DP, Marciniak B, Pulaski L. Stem Cell Res. 2020 Jul;46:101858. doi: 10.1016/j.scr.2020.101858. Epub 2020 Jun 1. PubMed |
DEPDC5 haploinsufficiency drives increased mTORC1 signaling and abnormal morphology in human iPSC-derived cortical neurons. Klofas LK, Short BP, Snow JP, Sinnaeve J, Rushing GV, Westlake G, Weinstein W, Ihrie RA, Ess KC, Carson RP. Neurobiol Dis. 2020 Sep;143:104975. doi: 10.1016/j.nbd.2020.104975. Epub 2020 Jun 20. PubMed |
CRISPR/Cas9 treatment causes extended TP53-dependent cell cycle arrest in human cells. Geisinger JM, Stearns T. Nucleic Acids Res. 2020 Sep 18;48(16):9067-9081. doi: 10.1093/nar/gkaa603. PubMed |
Generation of an induced pluripotent stem cell line, CSSi011-A (6534), from an Amyotrophic lateral sclerosis patient with heterozygous L145F mutation in SOD1 gene. D'Anzi A, Altieri F, Perciballi E, Ferrari D, Bernardini L, Goldoni M, Mazzini L, De Marchi F, Di Pierro A, D'Alfonso S, Gelati M, Vescovi AL, Rosati J. Stem Cell Res. 2020 Jul 25;47:101924. doi: 10.1016/j.scr.2020.101924. PubMed |
Deriving Keratinocyte Progenitor Cells and Keratinocytes from Human-Induced Pluripotent Stem Cells. Ibrahim MR, Medhat W, El-Fakahany H, Abdel-Raouf H, Snyder EY. Curr Protoc Stem Cell Biol. 2020 Sep;54(1):e119. doi: 10.1002/cpsc.119. PubMed |
Differential gene expression elicited by ZIKV infection in trophoblasts from congenital Zika syndrome discordant twins. Amaral MS, Goulart E, Caires-Junior LC, Morales-Vicente DA, Soares-Schanoski A, Gomes RP, Olberg GGO, Astray RM, Kalil JE, Zatz M, Verjovski-Almeida S. PLoS Negl Trop Dis. 2020 Aug 3;14(8):e0008424. doi: 10.1371/journal.pntd.0008424. eCollection 2020 Aug. PubMed |
Generation of OCT4-EGFP, NANOG-tdTomato dual reporter human induced pluripotent stem cell line, KKUi001-A, using the CRISPR/Cas9 system. Lee M, Choi NY, Park S, Bang JS, Lee Y, Jeong D, Ham S, Lim S, Kim KH, Ko K. Stem Cell Res. 2020 Oct;48:101943. doi: 10.1016/j.scr.2020.101943. Epub 2020 Aug 3. PubMed |
Generation and characterization of iPSC lines (BGUi004-A, BGUi005-A) from two identical twins with polyalanine expansion in the paired-like homeobox 2B (PHOX2B) gene. Falik D, Rabinski T, Zlotnik D, Eshel R, Zorsky M, Garin-Shkolnik T, Ofir R, Adato A, Ashkenazi A, Vatine GD. Stem Cell Res. 2020 Oct;48:101955. doi: 10.1016/j.scr.2020.101955. Epub 2020 Aug 14. PubMed |
Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA. Wang K, Lin RZ, Hong X, Ng AH, Lee CN, Neumeyer J, Wang G, Wang X, Ma M, Pu WT, Church GM, Melero-Martin JM. Sci Adv. 2020 Jul 24;6(30):eaba7606. doi: 10.1126/sciadv.aba7606. eCollection 2020 Jul. PubMed |
Generation of iPSC lines from two (BGUi002-A and BGUi003-A) homozygous p450 oxidoreductase-deficient patients and from one (BGUi001-A) heterozygous healthy family relative. Zlotnik D, Rabinski T, Ofir R, Hershkovitz E, Vatine GD. Stem Cell Res. 2020 Oct;48:101975. doi: 10.1016/j.scr.2020.101975. Epub 2020 Sep 1. PubMed |
Derivation of induced pluripotent stem cells (SDUKIi003-A) from a 20-year-old male patient diagnosed with Asperger syndrome. Kamand M, Ilieva M, Louise Forsberg S, Thomassen M, Meyer M, Fex Svenningsen A, Maria Michel T. Stem Cell Res. 2020 Oct;48:101974. doi: 10.1016/j.scr.2020.101974. Epub 2020 Sep 1. PubMed |
Generation of autism spectrum disorder patient-derived iPSC line SDUKIi004-A. Kamand M, Ilieva M, Forsberg SL, Thomassen M, Svenningsen AF, Meyer M, Michel TM. Stem Cell Res. 2020 Dec;49:102038. doi: 10.1016/j.scr.2020.102038. Epub 2020 Oct 8. PubMed |
An epilepsy-associated ACTL6B variant captures neuronal hyperexcitability in a human induced pluripotent stem cell model. Ahn LY, Coatti GC, Liu J, Gumus E, Schaffer AE, Miranda HC. J Neurosci Res. 2021 Jan;99(1):110-123. doi: 10.1002/jnr.24747. Epub 2020 Nov 3. PubMed |
16p11.2 microdeletion imparts transcriptional alterations in human iPSC-derived models of early neural development. Roth JG, Muench KL, Asokan A, Mallett VM, Gai H, Verma Y, Weber S, Charlton C, Fowler JL, Loh KM, Dolmetsch RE, Palmer TD. Elife. 2020 Nov 10;9. pii: 58178. doi: 10.7554/eLife.58178. PubMed |
Generation of Human iPSCs by Episomal Reprogramming of Skin Fibroblasts and Peripheral Blood Mononuclear Cells. Febbraro F, Chen M, Denham M. Methods Mol Biol. 2021;2239:135-151. doi: 10.1007/978-1-0716-1084-8_9. PubMed |
Generation of an induced pluripotent stem cell line from an Alstrom Syndrome patient with ALMS1 mutation (c.3902C > A, c.6436C > T) and a gene correction isogenic iPSC line. Ji X, Tang Q, Tang C, Wu Z, Ma L, Guo X, Cheng G, Chen Y, Yang T, Xiong M, Zhou W. Stem Cell Res. 2020 Dec;49:102089. doi: 10.1016/j.scr.2020.102089. Epub 2020 Nov 17. PubMed |
Generation of an induced pluripotent stem cell line SMBCi010-A from a male with Multiple Osteochondroma carrying a EXT1 mutation. Cui Y, Wang J, Zhang G, Luan J, Han J. Stem Cell Res. 2020 Dec 7;50:102111. doi: 10.1016/j.scr.2020.102111. PubMed |
Establishment of an iPSC line (CSUXHi003-A) from a patient with Waardenburg syndrome type caused by a MITF mutation. Wen J, Song J, He C, Ling J, Liu Y, Chen H, Gong W, Mei L, Feng Y. Stem Cell Res. 2021 Mar;51:102157. doi: 10.1016/j.scr.2021.102157. Epub 2021 Jan 9. PubMed |
Reprogramming of two induced pluripotent stem cell lines from a heterozygous GRIN2D developmental and epileptic encephalopathy (DEE) patient (BGUi011-A) and from a healthy family relative (BGUi012-A). Rabinski T, Sagiv ST, Hausman-Kedem M, Fattal-Valevski A, Rubinstein M, Avraham KB, Vatine GD. Stem Cell Res. 2021 Mar;51:102178. doi: 10.1016/j.scr.2021.102178. Epub 2021 Jan 15. PubMed |
Establishment of an induced pluripotent stem (iPS) cell line (SDUKIi006-A) from a 21-year old male patient diagnosed with atypical autism disorder. Kamand M, Forsberg SL, Thomassen M, Ilieva M, Meyer M, Svenningsen AF, Michel TM. Stem Cell Res. 2021 Mar;51:102185. doi: 10.1016/j.scr.2021.102185. Epub 2021 Jan 18. PubMed |
A human model of Batten disease shows role of CLN3 in phagocytosis at the photoreceptor-RPE interface. Tang C, Han J, Dalvi S, Manian K, Winschel L, Volland S, Soto CA, Galloway CA, Spencer W, Roll M, Milliner C, Bonilha VL, Johnson TB, Latchney L, Weimer JM, Augustine EF, Mink JW, Gullapalli VK, Chung M, Williams DS, Singh R. Commun Biol. 2021 Feb 5;4(1):161. doi: 10.1038/s42003-021-01682-5. PubMed |
Generation of a human induced pluripotent stem cells (MUi015-A) from skin fibroblast of retinoblastoma patient with 13q deletion syndrome. Tangprasittipap A, Chumchuen S, Pornratananont G, Kitiyanant N, Hongeng S. Stem Cell Res. 2021 Apr;52:102211. doi: 10.1016/j.scr.2021.102211. Epub 2021 Jan 29. PubMed |
Generation of six induced pluripotent stem cell lines from patients with amyotrophic lateral sclerosis with associated genetic mutations in either FUS or ANXA11. Hedges EC, Topp S, Shaw CE, Nishimura AL. Stem Cell Res. 2021 Apr;52:102246. doi: 10.1016/j.scr.2021.102246. Epub 2021 Feb 12. PubMed |
Monitoring Axonal Degeneration in Human Pluripotent Stem Cell Models of Hereditary Spastic Paraplegias. Li XJ, Mou Y, Milton C, Chen Z. Methods Mol Biol. 2021 Mar 27. doi: 10.1007/7651_2021_379. PubMed |
Derivation of Induced Pluripotent Stem Cell (iPSC) Lines from Patient-Specific Peripheral Blood Mononuclear Cells (PBMC) Using Episomal Vectors. Konala VBR, Nandakumar S, Surendran H, Pal R. Methods Mol Biol. 2021 Mar 27. doi: 10.1007/7651_2021_385. PubMed |
Establishment of an iPSC line (CSUXHi004-A) from a patient with Waardenburg syndrome type I caused by a PAX3 splice mutation. Wen J, He C, Feng Y, Song J, Liu J, Liu X, Mei L, Ling J, Chen H, Liu Y. Stem Cell Res. 2021 May;53:102300. doi: 10.1016/j.scr.2021.102300. Epub 2021 Mar 18. PubMed |
3D iPSC modeling of the retinal pigment epithelium-choriocapillaris complex identifies factors involved in the pathology of macular degeneration. Manian KV, Galloway CA, Dalvi S, Emanuel AA, Mereness JA, Black W, Winschel L, Soto C, Li Y, Song Y, DeMaria W, Kumar A, Slukvin I, Schwartz MP, Murphy WL, Anand-Apte B, Chung M, Benoit DSW, Singh R. Cell Stem Cell. 2021 May 6;28(5):846-862.e8. doi: 10.1016/j.stem.2021.02.006. Epub 2021 Mar 29. PubMed |
Generation of human induced pluripotent stem cell line (MUi026-A) from a patient with autosomal dominant polycystic kidney disease carrying PKD1 point mutation. Maneepitasut W, Wongkummool W, Tong-Ngam P, Promthep K, Tubsuwan A, Khine Linn A, Phakdeekitcharoen B, Borwornpinyo S, Kitiyanant N, Phanthong P, Hongeng S. Stem Cell Res. 2021 May;53:102306. doi: 10.1016/j.scr.2021.102306. Epub 2021 Mar 22. PubMed |
Generation of two induced pluripotent stem cell lines from patients with X-linked Alport syndrome. Ma Y, Wang Z, Gao M, Liu X, Sun W, Gong Y, Sun G, Liu G. Stem Cell Res. 2021 May;53:102343. doi: 10.1016/j.scr.2021.102343. Epub 2021 Apr 17. PubMed |
Restoration of visual function in advanced disease after transplantation of purified human pluripotent stem cell-derived cone photoreceptors. Ribeiro J, Procyk CA, West EL, O'Hara-Wright M, Martins MF, Khorasani MM, Hare A, Basche M, Fernando M, Goh D, Jumbo N, Rizzi M, Powell K, Tariq M, Michaelides M, Bainbridge JWB, Smith AJ, Pearson RA, Gonzalez-Cordero A, Ali RR. Cell Rep. 2021 Apr 20;35(3):109022. doi: 10.1016/j.celrep.2021.109022. PubMed |
Generation of induced pluripotent stem cell line (IGIBi007-A) from a patient with a novel acromesomelic dysplasia, PRKG2 type (AMDP). Kumar M, Wadhwa S, Tyagi N, Ahmad I, Kumar S, Sagar S, Zahra S, Kamai A, Shamim U, Kapoor S, Faruq M. Stem Cell Res. 2021 May;53:102340. doi: 10.1016/j.scr.2021.102340. Epub 2021 Apr 19. PubMed |
Chronically Elevated Exogenous Glucose Elicits Antipodal Effects on the Proteome Signature of Differentiating Human iPSC-Derived Pancreatic Progenitors. Ghila L, Legoy TA, Mathisen AF, Abadpour S, Paulo JA, Scholz H, Raeder H, Chera S. Int J Mol Sci. 2021 Apr 2;22(7). pii: ijms22073698. doi: 10.3390/ijms22073698. PubMed |
Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant beta cells. Low BSJ, Lim CS, Ding SSL, Tan YS, Ng NHJ, Krishnan VG, Ang SF, Neo CWY, Verma CS, Hoon S, Lim SC, Tai ES, Teo AKK. Nat Commun. 2021 May 25;12(1):3133. doi: 10.1038/s41467-021-22843-4. PubMed |
Transcriptome analysis of MBD5-associated neurodevelopmental disorder (MAND) neural progenitor cells reveals dysregulation of autism-associated genes. Mullegama SV, Klein SD, Williams SR, Innis JW, Probst FJ, Haldeman-Englert C, Martinez-Agosto JA, Yang Y, Tian Y, Elsea SH, Ezashi T. Sci Rep. 2021 May 28;11(1):11295. doi: 10.1038/s41598-021-90798-z. PubMed |
Generation of an induced pluripotent stem cell line (CSS012-A (7672)) carrying the p.G376D heterozygous mutation in the TARDBP protein. D'Anzi A, Altieri F, Perciballi E, Ferrari D, Torres B, Bernardini L, Lattante S, Sabatelli M, Vescovi AL, Rosati J. Stem Cell Res. 2021 May;53:102356. doi: 10.1016/j.scr.2021.102356. Epub 2021 Apr 18. PubMed |
Establishing an induced pluripotent stem cell line from neonatal common marmoset fibroblasts by an all-in-one episomal vector approach.
Yoshimatsu S, Qian E, Sato T, Yamamoto M, Ishikawa M, Okano H.
Stem Cell Res. 2021 May;53:102380. doi: 10.1016/j.scr.2021.102380. Epub 2021 Apr 30.
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AKT Signaling Modifies the Balance between Cell Proliferation and Migration in Neural Crest Cells from Patients Affected with Bosma Arhinia and Microphthalmia Syndrome. Laberthonniere C, Novoa-Del-Toro EM, Chevalier R, Broucqsault N, Rao VV, Trani JP, Nguyen K, Xue S, Reversade B, Robin JD, Baudot A, Magdinier F. Biomedicines. 2021 Jun 29;9(7). pii: biomedicines9070751. doi: 10.3390/biomedicines9070751. PubMed |
Generation of an induced pluripotent stem cell line (IUFi001) from a Cockayne syndrome patient carrying a mutation in the ERCC6 gene. Martins S, Hacheney I, Teichweyde N, Hildebrandt B, Krutmann J, Rossi A. Stem Cell Res. 2021 Aug;55:102456. doi: 10.1016/j.scr.2021.102456. Epub 2021 Jul 7. PubMed |
Episomal vector reprogramming of human umbilical cord blood natural killer cells to an induced pluripotent stem cell line MUSIi013-A. Klaihmon P, Luanpitpong S, Lorthongpanich C, Laowtammathron C, Waeteekul S, Terbto P, Issaragrisil S. Stem Cell Res. 2021 Aug;55:102472. doi: 10.1016/j.scr.2021.102472. Epub 2021 Jul 21. PubMed |
Establishment of an integration-free human induced pluripotent stem cell line (TJCi001-A) from normal bone marrow-derived mesenchymal stem cells. Choi NY, Lee Y, Park YS, Ko K, Park B, Koh YG. Stem Cell Res. 2021 Aug;55:102484. doi: 10.1016/j.scr.2021.102484. Epub 2021 Aug 3. PubMed |
Simultaneous high-efficiency base editing and reprogramming of patient fibroblasts.
Jalil S, Keskinen T, Maldonado R, Sokka J, Trokovic R, Otonkoski T, Wartiovaara K.
Stem Cell Reports. 2021 Nov 16. pii: S2213-6711(21)00552-X. doi: 10.1016/j.stemcr.2021.10.017.
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Evaluation for Retinal Therapy for RPE65 Variation Assessed in hiPSC Retinal Pigment Epithelial Cells. Nash BM, Loi TH, Fernando M, Sabri A, Robinson J, Cheng A, Eamegdool SS, Farnsworth E, Bennetts B, Grigg JR, Chung SK, Gonzalez-Cordero A, Jamieson RV. Stem Cells Int. 2021 Dec 13;2021:4536382. doi: 10.1155/2021/4536382. eCollection 2021. PubMed |
CRISPR activation enables high-fidelity reprogramming into human pluripotent stem cells.
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Stem Cell Reports. 2022 Feb 8;17(2):413-426. doi: 10.1016/j.stemcr.2021.12.017. Epub 2022 Jan 20.
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Engineering human skin model innervated with itch sensory neuron-like cells differentiated from induced pluripotent stem cells. Guo Z, Tong CK, Jackow J, Doucet YS, Abaci HE, Zeng W, Hansen C, Hayashi R, DeLorenzo D, Rami A, Pappalardo A, Lumpkin EA, Christiano AM. Bioeng Transl Med. 2021 Aug 20;7(1):e10247. doi: 10.1002/btm2.10247. eCollection 2022 Jan. PubMed |
Establishment of human induced pluripotent stem cell line MUi028-A from normal fetal skin fibroblasts. Chumchuen S, Satirapod C, Tangprasittipap A, Hongeng S. Stem Cell Res. 2022 Apr;60:102675. doi: 10.1016/j.scr.2022.102675. Epub 2022 Jan 19. PubMed |
Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration. LaForce GR, Farr JS, Liu J, Akesson C, Gumus E, Pinkard O, Miranda HC, Johnson K, Sweet TJ, Ji P, Lin A, Coller J, Philippidou P, Wagner EJ, Schaffer AE. Neuron. 2022 Apr 20;110(8):1340-1357.e7. doi: 10.1016/j.neuron.2022.01.018. Epub 2022 Feb 8. PubMed |
A generation of human induced pluripotent stem cell line (MUi031-A) from a type-3 Gaucher disease patient carrying homozygous mutation on GBA1 gene. Pornsukjantra T, Kangboonruang K, Tong-Ngam P, Tim-Aroon T, Wattanasirichaigoon D, Anurathapan U, Hongeng S, Tubsuwan A, Bhukhai K, Asavapanumas N. Stem Cell Res. 2022 Apr;60:102698. doi: 10.1016/j.scr.2022.102698. Epub 2022 Feb 2. PubMed |
Generation of an induced pluripotent stem cell line from a healthy Caucasian male. Martinez-Moreno R, Perez-Serra A, Carreras D, Aran B, Kuebler B, Brugada R, Scornik FS, Perez GJ, Selga E. Stem Cell Res. 2022 Apr;60:102717. doi: 10.1016/j.scr.2022.102717. Epub 2022 Feb 22. PubMed |
Generation of Marfan patient specific iPSCs (ICSSUi001-A) carrying a novel heterozygous mutation in FBN1 gene. Yu Y, Shen H, Zhu J, Cao X, Li Q, Shao L, Shen Z. Stem Cell Res. 2022 Apr;60:102720. doi: 10.1016/j.scr.2022.102720. Epub 2022 Feb 24. PubMed |
Superoxide dismutase isozymes in cerebral organoids from autism spectrum disorder patients. Ejlersen M, Ilieva M, Michel TM. J Neural Transm (Vienna). 2022 Jun;129(5-6):617-626. doi: 10.1007/s00702-022-02472-x. Epub 2022 Mar 9. PubMed |
Label-Free Imaging to Track Reprogramming of Human Somatic Cells. Molugu K, Battistini GA, Heaster TM, Rouw J, Guzman EC, Skala MC, Saha K. GEN Biotechnol. 2022 Apr 1;1(2):176-191. doi: 10.1089/genbio.2022.0001. Epub 2022 Apr 20. PubMed |
Myoglobin expression by alternative transcript in different mesenchymal stem cells compartments. Scrima R, Agriesti F, Pacelli C, Piccoli C, Pucci P, Amoresano A, Cela O, Nappi L, Tataranni T, Mori G, Formisano P, Capitanio N. Stem Cell Res Ther. 2022 May 21;13(1):209. doi: 10.1186/s13287-022-02880-6. PubMed |
Altered patterning of trisomy 21 interneuron progenitors. Giffin-Rao Y, Sheng J, Strand B, Xu K, Huang L, Medo M, Risgaard KA, Dantinne S, Mohan S, Keshan A, Daley RA Jr, Levesque B, Amundson L, Reese R, Sousa AMM, Tao Y, Wang D, Zhang SC, Bhattacharyya A. Stem Cell Reports. 2022 Jun 14;17(6):1366-1379. doi: 10.1016/j.stemcr.2022.05.001. Epub 2022 May 26. PubMed |
Establishment and Characterization of MUi027-A: A Novel Patient-Derived Cell Line of Polycystic Kidney Disease with PKD1 Mutation. Linn AK, Maneepitasut W, Tubsuwan A, Kitiyanant N, Phakdeekitcharoen B, Borwornpinyo S, Hongeng S, Phanthong P. J Pers Med. 2022 May 9;12(5). pii: jpm12050766. doi: 10.3390/jpm12050766. PubMed |
Experimental method for haplotype phasing across the entire length of chromosome 21 in trisomy 21 cells using a chromosome elimination technique. Wakita S, Hara M, Kitabatake Y, Kawatani K, Kurahashi H, Hashizume R. J Hum Genet. 2022 May 31. pii: 10.1038/s10038-022-01049-6. doi: 10.1038/s10038-022-01049-6. PubMed |
Enhanced cortical neural stem cell identity through short SMAD and WNT inhibition in human cerebral organoids facilitates emergence of outer radial glial cells. Rosebrock D, Arora S, Mutukula N, Volkman R, Gralinska E, Balaskas A, Aragones Hernandez A, Buschow R, Brandl B, Muller FJ, Arndt PF, Vingron M, Elkabetz Y. Nat Cell Biol. 2022 Jun;24(6):981-995. doi: 10.1038/s41556-022-00929-5. Epub 2022 Jun 13. PubMed |
Production of CSSi013-A (9360) iPSC line from an asymptomatic subject carrying an heterozygous mutation in TDP-43 protein. D'Anzi A, Perciballi E, Ruotolo G, Ferrari D, Notaro A, Lombardi I, Gelati M, Frezza K, Bernardini L, Torrente I, De Luca A, La Bella V, Luigi Vescovi A, Rosati J. Stem Cell Res. 2022 Aug;63:102835. doi: 10.1016/j.scr.2022.102835. Epub 2022 Jun 6. PubMed |
Efficient embryoid-based method to improve generation of optic vesicles from human induced pluripotent stem cells. Eintracht J, Harding P, Lima Cunha D, Moosajee M. F1000Res. 2022 Mar 17;11:324. doi: 10.12688/f1000research.108829.1. eCollection 2022. PubMed |
Generation and Characterization of Novel iPSC Lines from a Portuguese Family Bearing Heterozygous and Homozygous GRN Mutations. Oliveira AR, Martins S, Cammarata G, Martins M, Cardoso AM, Almeida MR, do Carmo Macario M, Santana I, Peca J, Cardoso AL. Biomedicines. 2022 Aug 6;10(8):1905. doi: 10.3390/biomedicines10081905. PubMed |
DNA Methylation Profiles of GAD1 in Human Cerebral Organoids of Autism Indicate Disrupted Epigenetic Regulation during Early Development. Pearson G, Song C, Hohmann S, Prokhorova T, Sheldrick-Michel TM, Knopfel T. Int J Mol Sci. 2022 Aug 16;23(16):9188. doi: 10.3390/ijms23169188. PubMed |
Generation of transgene-free human induced pluripotent stem cells from erythroblasts in feeder-free conditions. Perriot S, Canales M, Mathias A, Du Pasquier R. STAR Protoc. 2022 Aug 17;3(3):101620. doi: 10.1016/j.xpro.2022.101620. eCollection 2022 Sep 16. PubMed |
Sigma non-opioid receptor 1 is a potential therapeutic target for long QT syndrome. Song L, Bekdash R, Morikawa K, Quejada JR, Klein AD, Aina-Badejo D, Yoshida K, Yamamoto HE, Chalan A, Yang R, Patel A, Sirabella D, Lee TM, Joseph LC, Kawano F, Warren JS, Soni RK, Morrow JP, Yazawa M. Nat Cardiovasc Res. 2022 Feb;1(2):142-156. doi: 10.1038/s44161-021-00016-2. Epub 2022 Feb 17. PubMed |
Customized strategies for high-yield purification of retinal pigment epithelial cells differentiated from different stem cell sources. Regha K, Bhargava M, Al-Mubaarak A, Chai C, Parikh BH, Liu Z, Wong CSW, Hunziker W, Lim KL, Su X. Sci Rep. 2022 Sep 16;12(1):15563. doi: 10.1038/s41598-022-19777-2. PubMed |
Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration. Tian H, Chen Z, Zhu X, Ou Q, Wang Z, Wu B, Xu JY, Jin C, Gao F, Wang J, Zhang J, Zhang J, Lu L, Xu GT. iScience. 2022 Sep 2;25(10):105050. doi: 10.1016/j.isci.2022.105050. eCollection 2022 Oct 21. PubMed |
A generation of human-induced pluripotent stem cell line (MUi032-A) from a Choroideremia disease patient carrying a hemizygous mutation on the CHM gene. Pongpaksupasin P, Wongkummool W, Tong-Ngam P, Jearawiriyapaisarn N, Paiboonsukwong K, Sangkitporn S, Trinavarat A, Atchaneeyasakul LO, Tubsuwan A. Stem Cell Res. 2022 Dec;65:102964. doi: 10.1016/j.scr.2022.102964. Epub 2022 Nov 11. PubMed |
Biofabrication of synthetic human liver tissue with advanced programmable functions. Florentino RM, Morita K, Haep N, Motomura T, Diaz-Aragon R, Faccioli LAP, Collin de l'Hortet A, Cetin Z, Frau C, Vernetti L, Amler AK, Thomas A, Lam T, Kloke L, Takeishi K, Taylor DL, Fox IJ, Soto-Gutierrez A. iScience. 2022 Nov 4;25(12):105503. doi: 10.1016/j.isci.2022.105503. eCollection 2022 Dec 22. PubMed |
Generation of neural organoids for spinal-cord regeneration via the direct reprogramming of human astrocytes. Xu J, Fang S, Deng S, Li H, Lin X, Huang Y, Chung S, Shu Y, Shao Z. Nat Biomed Eng. 2023 Mar;7(3):253-269. doi: 10.1038/s41551-022-00963-6. Epub 2022 Nov 24. PubMed |
Generation of human induced pluripotent stem cell line (MUi034-A) from an unusual case of hydrops fetalis associated with homozygous hemoglobin Constant Spring. Wongkummool W, Tong-Ngam P, Munkongdee T, Tangprasittipap A, Paiboonsukwong K, Hongeng S, Fucharoen S, Charoenkwan P, Tubsuwan A. Stem Cell Res. 2022 Dec;65:102979. doi: 10.1016/j.scr.2022.102979. Epub 2022 Nov 18. PubMed |
Generation of feeder-independent transgene-free iPSC lines from a young-onset Parkinson's disease (YOPD) patient with a homozygous PLA2G6: c.2222G>A (p. Arg741Gln) mutation (NCBSi003-A) and unaffected heterozygous parent (NCBSi004-A). Gopurappilly R, Musthafa T, Sukumaran S, Viswanath B, Hasan G. Stem Cell Res. 2023 Mar;67:103033. doi: 10.1016/j.scr.2023.103033. Epub 2023 Jan 24. PubMed |
Extracellular vesicles from iPSC-MSCs alleviate chemotherapy-induced mouse ovarian damage via the ILK-PI3K/AKT pathway. Cao RC, Lv Y, Lu G, Liu HB, Wang W, Tan C, Su XW, Xiong Z, Ma JL, Chan WY. Zool Res. 2023 May 18;44(3):620-635. doi: 10.24272/j.issn.2095-8137.2022.340. PubMed |
Retinal Organoids from an AIPL1 CRISPR/Cas9 Knockout Cell Line Successfully Recapitulate the Molecular Features of LCA4 Disease. Perdigao PRL, Ollington B, Sai H, Leung A, Sacristan-Reviriego A, van der Spuy J. Int J Mol Sci. 2023 Mar 21;24(6):5912. doi: 10.3390/ijms24065912. PubMed |
HiPSC-derived cardiomyocyte to model Brugada syndrome: both asymptomatic and symptomatic mutation carriers reveal increased arrhythmogenicity. Penttinen K, Prajapati C, Shah D, Rajan DK, Cherian RM, Swan H, Aalto-Setala K. BMC Cardiovasc Disord. 2023 Apr 25;23(1):208. doi: 10.1186/s12872-023-03234-7. PubMed |
Generation of control human iPSC line INSTEMi001-A from PBMCs of a healthy Indian donor. Patlolla N, Ponnachan P, Jamora C, Abbey D. Stem Cell Res. 2023 Jun;69:103112. doi: 10.1016/j.scr.2023.103112. Epub 2023 May 4. PubMed |
Generation of an Open-Access Patient-Derived iPSC Biobank for Amyotrophic Lateral Sclerosis Disease Modelling. Hedges EC, Cocks G, Shaw CE, Nishimura AL. Genes (Basel). 2023 May 18;14(5):1108. doi: 10.3390/genes14051108. PubMed |
Direct haplotype-resolved 5-base HiFi sequencing for genome-wide profiling of hypermethylation outliers in a rare disease cohort. Cheung WA, Johnson AF, Rowell WJ, Farrow E, Hall R, Cohen ASA, Means JC, Zion TN, Portik DM, Saunders CT, Koseva B, Bi C, Truong TK, Schwendinger-Schreck C, Yoo B, Johnston JJ, Gibson M, Evrony G, Rizzo WB, Thiffault I, Younger ST, Curran T, Wenger AM, Grundberg E, Pastinen T. Nat Commun. 2023 May 29;14(1):3090. doi: 10.1038/s41467-023-38782-1. PubMed |
Pluripotency-independent induction of human trophoblast stem cells from fibroblasts. Naama M, Rahamim M, Zayat V, Sebban S, Radwan A, Orzech D, Lasry R, Ifrah A, Jaber M, Sabag O, Yassen H, Khatib A, Epsztejn-Litman S, Novoselsky-Persky M, Makedonski K, Deri N, Goldman-Wohl D, Cedar H, Yagel S, Eiges R, Buganim Y. Nat Commun. 2023 Jun 8;14(1):3359. doi: 10.1038/s41467-023-39104-1. PubMed |
Targeted viral adaptation generates a simian-tropic hepatitis B virus that infects marmoset cells. Liu Y, Cafiero TR, Park D, Biswas A, Winer BY, Cho CH, Bram Y, Chandar V, Connell AKO, Gertje HP, Crossland N, Schwartz RE, Ploss A. Nat Commun. 2023 Jun 16;14(1):3582. doi: 10.1038/s41467-023-39148-3. PubMed |
Null and missense mutations of ERI1 cause a recessive phenotypic dichotomy in humans. Guo L, Salian S, Xue JY, Rath N, Rousseau J, Kim H, Ehresmann S, Moosa S, Nakagawa N, Kuroda H, Clayton-Smith J, Wang J, Wang Z, Banka S, Jackson A, Zhang YM, Wei ZJ, Huning I, Brunet T, Ohashi H, Thomas MF, Bupp C, Miyake N, Matsumoto N, Mendoza-Londono R, Costain G, Hahn G, Di Donato N, Yigit G, Yamada T, Nishimura G, Ansel KM, Wollnik B, Hrabe de Angelis M, Megarbane A, Rosenfeld JA, Heissmeyer V, Ikegawa S, Campeau PM. Am J Hum Genet. 2023 Jul 6;110(7):1068-1085. doi: 10.1016/j.ajhg.2023.06.001. Epub 2023 Jun 22. PubMed |
Microglia produce the amyloidogenic ABri peptide in familial British dementia. Arber C, Casey JM, Crawford S, Rambarack N, Yaman U, Wiethoff S, Augustin E, Piers TM, Rostagno A, Ghiso J, Lewis PA, Revesz T, Hardy J, Pocock JM, Houlden H, Schott JM, Salih DA, Lashley T, Wray S. bioRxiv. 2023 Jun 28:2023.06.27.546552. doi: 10.1101/2023.06.27.546552. Preprint. PubMed |
Establishment and characterization of CSCRi006-A: an induced pluripotent stem cell line generated from a patient with Diamond-Blackfan Anemia (DBA) carrying ribosomal protein S19 (RPS19) mutation. Rani S, Thamodaran V, Nandy K, Fouzia NA, Maddali M, Rajesh P, Vijayanand S, David E, Velayudhan SR. Hum Cell. 2023 Nov;36(6):2204-2213. doi: 10.1007/s13577-023-00946-y. Epub 2023 Aug 21. PubMed |
In vivo tracking transplanted cardiomyocytes derived from human induced pluripotent stem cells using nuclear medicine imaging. Saito Y, Nose N, Iida T, Akazawa K, Kanno T, Fujimoto Y, Sasaki T, Akehi M, Higuchi T, Akagi S, Yoshida M, Miyoshi T, Ito H, Nakamura K. Front Cardiovasc Med. 2023 Sep 7;10:1261330. doi: 10.3389/fcvm.2023.1261330. eCollection 2023. PubMed |
PAX4 loss of function increases diabetes risk by altering human pancreatic endocrine cell development. Lau HH, Krentz NAJ, Abaitua F, Perez-Alcantara M, Chan JW, Ajeian J, Ghosh S, Lee Y, Yang J, Thaman S, Champon B, Sun H, Jha A, Hoon S, Tan NS, Gardner DS, Kao SL, Tai ES, Gloyn AL, Teo AKK. Nat Commun. 2023 Sep 30;14(1):6119. doi: 10.1038/s41467-023-41860-z. PubMed |
A model of human neural networks reveals NPTX2 pathology in ALS and FTLD. Hruska-Plochan M, Wiersma VI, Betz KM, Mallona I, Ronchi S, Maniecka Z, Hock EM, Tantardini E, Laferriere F, Sahadevan S, Hoop V, Delvendahl I, Perez-Berlanga M, Gatta B, Panatta M, van der Bourg A, Bohaciakova D, Sharma P, De Vos L, Frontzek K, Aguzzi A, Lashley T, Robinson MD, Karayannis T, Mueller M, Hierlemann A, Polymenidou M. Nature. 2024 Feb;626(8001):1073-1083. doi: 10.1038/s41586-024-07042-7. Epub 2024 Feb 14. PubMed |
Differentiation of Human-induced Pluripotent Stem Cell-derived Dental Stem Cells through Epithelial-Mesenchymal Interaction. Kim JH, Yang J, Ki MG, Jeon DH, Kim JW, Jang M, Lee G. Stem Cells Dev. 2024 Apr;33(7-8):189-199. doi: 10.1089/scd.2023.0220. Epub 2024 Mar 21. PubMed |
WNT signalling control by KDM5C during development affects cognition. Karwacki-Neisius V, Jang A, Cukuroglu E, Tai A, Jiao A, Predes D, Yoon J, Brookes E, Chen J, Iberg A, Halbritter F, Ounap K, Gecz J, Schlaeger TM, Ho Sui S, Goke J, He X, Lehtinen MK, Pomeroy SL, Shi Y. Nature. 2024 Mar;627(8004):594-603. doi: 10.1038/s41586-024-07067-y. Epub 2024 Feb 21. PubMed |
Generation of Leber congenital amaurosis, type 12 patient-specific induced pluripotent stem cell line (LVPEIi006-A), harboring a homozygous mutation in RD3. Mahato S, Maddileti S, Naik M, Kannabiran C, Jalali S, Mariappan I. Stem Cell Res. 2024 Jun;77:103380. doi: 10.1016/j.scr.2024.103380. Epub 2024 Mar 10. PubMed |
Generation and characterization of iPSC lines from Friedreich's ataxia patient (FRDA) with GAA.TTC repeat expansion in the Frataxin (FXN) gene's first intron (IGIBi016-A) and a non-FRDA healthy control individual (IGIBi017-A). Ahmad I, Kamai A, Zahra S, Kapoor H, Kumar Srivastava A, Faruq M. Stem Cell Res. 2024 Jun;77:103382. doi: 10.1016/j.scr.2024.103382. Epub 2024 Mar 11. PubMed |
Generation of marmoset primordial germ cell-like cells under chemically defined conditions. Kurlovich J, Rodriguez Polo I, Dovgusha O, Tereshchenko Y, Cruz CRV, Behr R, Gunesdogan U. Life Sci Alliance. 2024 Mar 18;7(6):e202302371. doi: 10.26508/lsa.202302371. Print 2024 Jun. PubMed |
Reactive astrocytes secrete the chaperone HSPB1 to mediate neuroprotection. Yang F, Beltran-Lobo P, Sung K, Goldrick C, Croft CL, Nishimura A, Hedges E, Mahiddine F, Troakes C, Golde TE, Perez-Nievas BG, Hanger DP, Noble W, Jimenez-Sanchez M. Sci Adv. 2024 Mar 22;10(12):eadk9884. doi: 10.1126/sciadv.adk9884. Epub 2024 Mar 20. PubMed |
Transgene-Free Cynomolgus Monkey iPSCs Generated under Chemically Defined Conditions. Tereshchenko Y, Esiyok N, Garea-Rodriguez E, Repetto D, Behr R, Rodriguez-Polo I. Cells. 2024 Mar 21;13(6):558. doi: 10.3390/cells13060558. PubMed |
Effects of the nerve agent VX on hiPSC-derived motor neurons. Schaefers C, Schmeisser W, John H, Worek F, Rein T, Rothmiller S, Schmidt A. Arch Toxicol. 2024 Jun;98(6):1859-1875. doi: 10.1007/s00204-024-03708-3. Epub 2024 Mar 30. PubMed |
Possible involvement of zinc transporter ZIP13 in myogenic differentiation. Shoji M, Ohashi T, Nagase S, Yuri H, Ichihashi K, Takagishi T, Nagata Y, Nomura Y, Fukunaka A, Kenjou S, Miyake H, Hara T, Yoshigai E, Fujitani Y, Sakurai H, Dos Santos HG, Fukada T, Kuzuhara T. Sci Rep. 2024 Apr 12;14(1):8052. doi: 10.1038/s41598-024-56912-7. PubMed |
Generation of integration-free human induced pluripotent stem cells from a patient with sporadic Parkinson's disease. Lee Y, Jeong D, Ham S, Son J, Ko K. Stem Cell Res. 2024 Jun;77:103416. doi: 10.1016/j.scr.2024.103416. Epub 2024 Apr 8. PubMed |
Generation of two induced pluripotent stem cell lines (LVPEIi004-A and LVPEIi005-A) from probands with Leber Congenital Amaurosis 2 (LCA2) and harboring mutations in RPE65. Maddileti S, Mahato S, Agrawal T, Pravin Dave V, Naik M, Javed Ali M, Kannabiran C, Jalali S, Jayandharan GR, Mariappan I. Stem Cell Res. 2024 Jun;77:103413. doi: 10.1016/j.scr.2024.103413. Epub 2024 Apr 16. PubMed |
Generation of a human iPSC line from a Parkinson's disease patient with a novel CHCHD2 mutation (p.R145Q). Chen X, Sun J, Wang T, Tang Q, Su L, Sun Y, Chen L, Seo H, Cheng T, Wang J, Song B. Stem Cell Res. 2024 Jun;77:103419. doi: 10.1016/j.scr.2024.103419. Epub 2024 Apr 9. PubMed |
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