Viral Vector Packaging Service: Molecular Tools
Tetracycline Transactivators and Inducible Tools
These AAV encode tetracycline-inducible tools/controls and tetracycline transactivators that can be used with tetracycline (tet)-inducible expression systems.
| ID | Name | Expression System | Activity | Serotype | PI |
|---|---|---|---|---|---|
| 99118 | pAAV-CAG-tTA | CAG-driven, constitutive | Expression of the tet-off transactivator (tTA) | 2 | Gradinaru |
| 99120 | pAAV-ihSyn1-tTA | Inducible Synapsin promoter (ihSyn) | Expression of the tet-off transactivator (tTA) with a positive feedback loop for amplified tTA expression. | 1 | Gradinaru |
| 99121 | pAAV-ihSyn1-DIO-tTA | Cre-dependent and inducible Synapsin promoter (ihSyn) | Cre-dependent expression of the tet-off transactivator (tTA) with a positive feedback loop for amplified tTA expression. | 1 | Gradinaru |
| 117383 | TRE-DIO-eYFP | Cre-dependent and Tetracycline-inducible | Cre-dependent, Tet-inducible expression of EYFP | 1 | Gradinaru |
Tools for Affinity Purification
These AAV encode tools for affinity purification (which can be used for viral TRAP).
| ID | Name | Expression System | Activity | Serotype | PI |
|---|---|---|---|---|---|
| 98747 | pAAV-FLEX-EGFPL10a | EF1a-driven and Cre-dependent | EGFP-tagged ribosomal L10a | 5, rg* | Heintz, Nectow, Schmidt |
Neurophysiology Tools
These AAV encode tools that can be used for neurophysiology experiments, including neuronal connectivity labeling.
| ID | Name | Expression System | Activity | Serotype | PI |
|---|---|---|---|---|---|
| 51509 | AAV phSyn1(S)-FLEX-tdTomato-T2A-SypEGFP-WPRE | Syn-driven, Cre-dependent | Cre-dependent expression of cytoplasmic tdTomato and synaptophysin-EGFP for labeling of axon terminals. | 1 | Zeng |
| 71760 | pAAV hSyn FLEx mGFP-2A-Synaptophysin-mRuby | Syn-driven, Cre-dependent | Cre-dependent expression of membrane-bound GFP and synaptophysin-mRuby for labeling of axon terminals. | 1 | Luo |
| 60658 | pAAV-EF1α-F-FLEX-mNaChBac-T2A-tdTomato | EF1a-driven, Flp-dependent | Flp-dependent expression of the voltage-gated Na+ channel mNaChBac and (physically separate) tdTomato | 8 | Scanziani |
Tools for Cell Ablation
These AAV encode tools that can be used for cell ablation.
| ID | Name | Expression System | Activity | Serotype | PI |
|---|---|---|---|---|---|
| 124364 | pAAV-FLEX-DTR-GFP | CBA-driven, Cre-dependent | Cre-dependent expression of diphtheria toxin receptor fused to GFP for studying cell ablation. | 2 | Jessell, Azim |
| 45580 | pAAV-flex-taCasp3-TEVp | EF1a-driven, Cre-dependent | Cre-dependent, bicistronic expression of designer pro-taCasp3 and TEVp for studying cell ablation. | 5 | Shah, Wells |
Don’t See What You’re Looking For?
Our Packaged on Request service offers you even more options. Select from a vast catalog of eligible AAV plasmids and we’ll make the viral vector prep you need.
Or fill out our form to let us know what you would like to see available in viral prep format. Please note this does not guarantee viral vector packaging service, but lets us know what viruses would be helpful to the scientific community.