...naturally-occurring Acr (Anti-CRISPR) proteins can help control CRISPR activity. Acr proteins have evolved...Orthologs Anti-CRISPR Small Edits HDR Base Edit Prime Edit Large Edits CRISPR Transposases CRISPR Integrases...Guide CRISPR Guide Jump To: CRISPR Guide Overview CRISPR Basics Basic Mechanisms Knockout Generation Multiplex...target tissue. Browse Plasmids: Anti-CRISPR Small Precision Edits CRISPR can be used to make small, very...screening using CRISPR libraries What Are Pooled Lentiviral CRISPR Libraries? Pooled lentiviral CRISPR libraries...References Website CRISPR plasmids and resources at Addgene CRISPR 101 eBook (3rd edition) CRISPR software and... Addgene Blog CRISPR topic page How to design your gRNA for CRISPR genome editing CRISPR 101: Homology...

...optogenetics plasmids available from Addgene. The popular CRISPR/Cas9 genome editing system has been modified for...vivo genome editing. For more information on AAV-CRISPR, please see this blog post. Browse the article ...serotype; in vivo , it displays very high infectivity across a broad range of cell types. The mutant AAV-DJ8...divided between two transfer plasmids, but with substantial sequence overlap. Co-expression induces homologous...with trans-splicing or overlapping vectors: a quantitative comparison. Duan D, Yue Y, Engelhardt JF. Mol...