...also express a gRNA, you will need to use a separate gRNA expression plasmid to target the dCas9-activator...Purify Tag Visualize dCas9-FokI Screen Pooled Libraries gRNAs Empty gRNA Vectors gRNAs By Species Mammalian... plasmids for activating or upregulating gene expression in various model organisms. CRISPR...transcriptional activation. Plasmids are available for expression in mammalian systems, bacteria, Drosophila, plants...Design Tools CRISPR Blog Posts Catalytically dead dCas9 fused to a transcriptional activator peptide can...specific gene. Design your gRNA sequence to direct the dCas9-activator to promoter or regulatory regions of your...

...visualize genomic loci. gRNAs Empty gRNA Vectors Select an empty vector for your experiment based on a variety...Regulation Activate dCas9 fused to an activator peptide activates gene expression. Interfere dCas9 alone, or fused...Epigenetics dCas9 fused to an epigenetic modifier alters chromatin structure/gene expression. RNA Targeting...powerful tool for genome-wide screening. Purify dCas9 fused to an epitope tag can be used to isolate a...

...Purify Tag Visualize dCas9-FokI Screen Pooled Libraries gRNAs Empty gRNA Vectors gRNAs By Species Mammalian... nickase plasmids. Plasmids are available for expression in mammalian systems, bacteria, Drosophila, plants...

...Purify Tag Visualize dCas9-FokI Screen Pooled Libraries gRNAs Empty gRNA Vectors gRNAs By Species Mammalian...Transposase plasmids. Plasmids are available for expression in mammalian systems and bacteria. Mammalian ...

...Purify Tag Visualize dCas9-FokI Screen Pooled Libraries gRNAs Empty gRNA Vectors gRNAs By Species Mammalian...to introduce a DSB. Plasmids are available for expression in mammalian systems, bacteria, Drosophila, plants...