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  1. Sonic Hedgehog? Sleeping Beauty? Learn About the Genes Behind Addgene’s Conference Room Names

    Type
    Blog Post
    Published
    April 2, 2019, 1:44 p.m.
    ...several plasmids that contain SHH, you can find them all here! The most popular SHH plasmid however was deposited... The mammalian hedgehog protein, sonic hedgehog (SHH) was named by a postdoc in Cliff Tabin’s lab who ...inspiration from a comic book his daughter was reading. SHH is involved in the hedgehog signalling pathway, which...key regulator of all bilateral animal development. SHH plays a key role in proper limb and digit formation...formation as well as neural development. Specifically, SHH is a morphogen, a chemical signal that diffuses down...depending on its concentration. Genetic mutations in SHH cause severe health conditions such as nonsyndromic...
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