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Showing: 121 - 140 of 442 results

  1. Fluorescent Proteins 101: History of Fluorescent Proteins

    Type
    Blog Post
    Published
    Aug. 7, 2017, 1:58 p.m.
    ...ring that glows with a faint green light. To investigate this green glimmer, Shimomura collected many,... in learning more about fluorescent proteins, I invite you to download our Fluorescent Protein eBook and...

  2. Microbes: Look, Listen, and Tell

    Type
    Blog Post
    Published
    Aug. 28, 2018, 12:04 p.m.
    ...exciting way of listening to microbes by using non-invasive methods for cellular imaging with ultrasound. ...Raymond W., et al. "Acoustic reporter genes for noninvasive imaging of microorganisms in mammalian hosts....

  3. Why Do I Need an MTA Anyway?

    Type
    Blog Post
    Published
    May 1, 2014, 8:23 p.m.
    ...Rights to all research results, modifications, and inventions created by the Recipient Right to file patent...patent applications on modifications or inventions Right to publish without editorial comment or review...

  5. Modulate the Activity of 17 Signaling Pathways with One Kit!

    Type
    Blog Post
    Published
    March 22, 2016, 2:30 p.m.
    ...sabatini-wood-cancer-pathway-orfs/ Finding signaling pathways involved in drug resistance Wood wanted to find out which...environments, for example. “We’ve been contacted by investigators all over the world who are interested to use...

  6. Management for Scientists: Seeking Feedback

    Type
    Blog Post
    Published
    Jan. 8, 2015, 2:34 p.m.
    ...information back. No team has all the answers – reinventing the wheel is inefficient. An effective team regularly...worry that it seems like "tattling" if others are involved. They may feel they are wasting their time. The...

  7. X-CHIME: Context Dependent Germline Knockout in Immune Cells

    Type
    Blog Post
    Published
    Jan. 16, 2024, 6:13 p.m.
    ...Annotation of genes in immune cells typically involves the creation of germline knockout mice, which ...To demonstrate the power of these systems to investigate in vivo mechanisms, we targeted two phosphatases...

  8. SciComm with the Experts at Science in the News Part 2

    Type
    Blog Post
    Published
    April 27, 2017, 2:30 p.m.
    ...University. There are tons of ways you can get involved in science communication. In this second half ...science communication student group and get more involved with your local community. What do Vini and Amy...

  9. Future of Research Conference - Remarkable Opening Session

    Type
    Blog Post
    Published
    Oct. 7, 2014, 3 p.m.
    ...current postdocs will be academic principal investigators. She also pointed out promising new practices...Your PI”.   She focused her talk on the issues involved with the fact that the PhD and Postdoc advisors...

  10. London Calling - Addgene’s New Europe Office in London

    Type
    Blog Post
    Published
    June 10, 2014, 3:20 p.m.
    ...plasmids to study the dimerization of HLA B27, involved in the onset of spondylarthritis, using Bioluminescence...than discussing a new scientific discovery or invention, and sharing those ideas with others. This love...

  11. Lentiviral CRISPR Libraries Enable Genome-Scale, Knockout Screening

    Type
    Blog Post
    Published
    Feb. 20, 2014, 4:57 p.m.
    ...melanoma model, they also went in search of genes involved in resistance to the cancer drug vemurafenib. ...lab has used their library to screen for genes involved in bacterial toxin resistance, identifying 4 previously...

  13. Sensing Neuronal Dopamine

    Type
    Blog Post
    Published
    July 30, 2019, 12:59 p.m.
    ... famous role as the “happy hormone,” it’s also involved in reinforcement learning, decision making, and...dopamine and other biosensors in our AAV vector inventory. References Darvesh, Altaf S., et al. "In vivo...

  14. Viral Vectors 101: Parts of the AAV Packaging Plasmid

    Type
    Blog Post
    Published
    Dec. 3, 2020, 2:15 p.m.
    ...two genes are found between the AAV genome’s two inverted terminal repeats (ITRs); but when recombinant ...through a pore in the capsid. Rep proteins are also involved in the transcriptional regulation of the AAV p40...

  15. CRISPR 101: Drug discovery and CRISPR

    Type
    Blog Post
    Published
    May 4, 2023, 1 p.m.
    ...discovery takes one of two approaches. The first route involves identifying a gene/pathway to develop a drug for...sometimes even genetic pathways that are worth investigating for drug development. Due to the difficulty ...

  16. Build Your CRISPR Vocabulary

    Type
    Blog Post
    Published
    July 2, 2024, 1:15 p.m.
    ...strand. Protein Cas: Different CRISPR systems involve different proteins, but many of them are called...require a tracrRNA. sgRNA: “Single-guide RNAs” were invented by synthetic biologists. An sgRNA combines a crRNA...

  17. Using Ultrasound to Image Bacteria in vivo: Acoustic Reporter Genes

    Type
    Blog Post
    Published
    June 19, 2018, 1:38 p.m.
    ...arg1 vesicles. Following collapse, vesicles are invisible to ultrasound, which allows for differentiation...Shapiro, M.G. (2018). Acoustic reporter genes for noninvasive imaging of microorganisms in mammalian hosts....

  18. Sleeping Beauty Awakens for Genome Engineering

    Type
    Blog Post
    Published
    June 30, 2015, 2 p.m.
    ...) The transposon consists of a mirrored set of inverted repeats (green) flanking the gene of interest ... enzyme is expressed (red stars) and binds the inverted repeats (green); and an endonuclease reaction ...

  19. 10 Ways to Share Your Science!

    Type
    Blog Post
    Published
    May 13, 2014, 8:34 p.m.
    ...Remember that people like a good story and science involves characters – in this case you – on a quest to ... and hopefully discover something new. Science involves success and, more often, failure. It’s useful ...

  20. In Vivo Biotinylation of Bacterial Fusion Proteins

    Type
    Blog Post
    Published
    Jan. 25, 2018, 2:09 p.m.
    ...determine the binding kinetics of a purified protein involves immobilization on a solid support. This allows...selectivity A common strategy to biotinylate proteins involves amine-reactive biotin derivatives that generate...
Showing: 121 - 140 of 442 results