...Find the allelic exchange vectors here! ShadowR, a novel FLIM-FRET acceptor Figure 4: ShadowR is used...A., Koga, N., & Nabekura, J. (2019). ShadowR: a novel chromoprotein with reduced non-specific binding ...

...postdoc positions, including AstraZeneca, Pfizer, Novartis, Biogen, Amgen, New England Biolabs, Regeneron...pre-approved project. Other companies, such as Novartis, have specific web sites for postdoc listings,...

...ligands. New fluorophores As a corollary to these innovative labeling strategies, several groups—including...infusion of photons for your imaging experiment. Innovative labeling strategies and improved fluorophores...

...pair editing window cannot edit within what Fyodor Urnov refers to as “PAM deserts” in the genome. More versatile...PMID: 31634902. Arezi, Bahram, and Holly Hogrefe. "Novel mutations in Moloney Murine Leukemia Virus reverse...

...incubation can be skipped by pre-binding to 1° Monovalent Monoclonal Only anti- rabbit and -mouse versions...Lee, C., Pleiner, T., Schliep, J.E., Stark, H., Trakhanov, S., & Urlaub, H. (2015). Nanobodies: site-specific...

...choice. ThermoFischers GeneArt Gene Synthesis NovoPro Labs Codon Optimization Tool (ExoOptimizer) Genewiz...Addgene;s dataset reveals trends in biological innovation Resources on Addgene.org Check out Addgene'...

...serotype-specific cap genes, and a plasmid encoding adenoviral helper sequences. AAV preparations are purified...Determination of Lentiviral Infectious Titer by a Novel Droplet Digital PCR Method. Human Gene Therapy Methods...

...mutation or morpholino. This observation unlocked novel research into genetic compensation, a previously...otherwise normal cell types are produced, rather than novel, abnormal cell types. Sequencing-based lineage tracing...

...program should “enable the ability to study life’s innovations from anywhere in the tree of life.” Accepted ... biomass). The lab is developing a system using novel vesicles to efficiently transform these cells which...

...neurons are activated when the mouse is placed in a novel context. As a proof-of-principle test, the authors...show that HR blocked neuronal activation in the novel context as determined by reduced c-fos expression...

...papers or are brainstorming new technological innovations. Let’s take a look at three historical techniques...past. In the sequencing world, one up and coming innovation is nanopore-based DNA sequencing which reads ...

...are not easily reversible. Late last year, the Akhmanova Lab published a new optogenetic tool for localized...Grigoriev, I., Nijenhuis, W., Kapitein, L. C., & Akhmanova, A. (2022). Opto-katanin, an optogenetic tool ...

...19 testing methods.   Rapid detection of 2019 novel coronavirus SARS-CoV-2 using a CRISPR based DETECTR...for rapid, ultrasensitive and visual detection of novel coronavirus SARS-CoV-2 Sensitivity: 4.6-11 copies...

...capable of inducing the brightest fluorescence (Filonov et al., 2014). Broccoli is twice as bright as Spinach2...9.10 (2014): 2412-2420. PubMed PMID: 25101481. Filonov, Grigory S., et al. "Broccoli: rapid selection ...

...e.g. mScarlet) or infrared fluorescent proteins (Chernov et al., 2017) may improve detection. Since longer...24360272. PubMed Central PMCID: PMC3918502.  14. Chernov, Konstantin G., et al. "Near-infrared fluorescent...

... can exchange ideas, network, collaborate, and innovate internationally. Why an International Mentorship...Spanish Secretary of Research, Development, and Innovation, D. Carmen Vela, who reiterated the Spanish government...

...strategies for combating cancers. To facilitate innovative cancer research, the Reference Reagents Group...robust CRISPR activators We previously reported on a novel Cas9-based activator developed by the Church lab...-X identified both previously characterized and novel mutants. Hess et al. envision CRISPR-X as not only...

...simplifies design of these constructs, allowing novice researchers to quickly and easily start genome ...technology into C. elegans has been a transformative innovation for our community. Developments in mammalian ...

...substrate-linked PEG, biotin, or magnetic beads. In one innovative example, the Zhang lab used SNAP-tag to decorate...Bulleit, R. F., & Wood, K. V. (2008). HaloTag: A Novel Protein Labeling Technology for Cell Imaging and...

...sites of infection or damage (Peters et al. 2008, Chtanova et al. 2008, Kamenyeva et al. 2015)? How do blood...18703742. PubMed Central PMCID: PMC2606057. 2. Chtanova, Tatyana, et al. "Dynamics of neutrophil migration...