...Wednesday we worked with the Harvard GSAS Science Policy Group to organize a Minisymposium on Reproducibility... posts on the defunct genome editing technology NgAgo). In addition, there are organizations like ReFigure.... Down the line we may see further adoption of policies that promote reproducible publishing practices...

... your experiment is definitely not a fluke.” 3. Engage in various projects and help colleagues with their...expertise in law, business, journalism, entertainment, politics, K-12, etc.” Addgene's team includes many PhD ...

... both knowledgeable in their field and eager to engage with the work of others. Having an environment ... with my teammates acted as my safety net and trampoline all at once. I was able to do something that ...

...be other scientists, or science journalists, or policy makers. The term editor covers a wide variety of...the Advancement of Science. She is enjoys broad engagement through science communication with a variety ...

...initially limit the technology to research centers engaged in long-term, mandatory follow-ups and observational...recognize so-called bad actors among them and “self-police” or whether the media and academic conference response...

...or contract, you should be starting to send out polite emails with your CV to people you’d like to work...scientists and technical people) is linked to engagement and access to growth opportunities, not salary...

... from audiences as they do science outreach and engage with the public, and learn from the process of ...broader impacts for their work in education and policy and to draw attention and support to work in their...

...Editing the PAM prevents the prime editor from re-engaging with DNA it has already edited. Created with BioRender.com... La to protect the end of the pegRNA. Adding 3′ polyU tracts to the end of pegRNAs (but not epegRNAs) ...

...engineered SpCas9 variants with alternative PAMs like NGAG and NGCG and SaCas9 with an NNGRRN PAM by mutagenizing...catalytically dead SpCas9 (dCas9) fused to the bacterial polymerase subunit ω. This construct is designed to activate...

..., including investigations into environmental pollutants and health, embryo growth, brain function, and...blocking initiation or splicing. (RNAi, in contrast, engages existing gene regulatory mechanisms to block activity...

... Fig. 2: Prime editor engaging target DNA. The reverse transcriptase polymerizes DNA onto the target strand...

...sharing cells: the black market of cell biology. Engaging in this practice would seem to save time and money...whether the cell lines had isoenzymes and genetic polymorphisms specific to their origins. This technique is...

...recombinant antibody. They are ~25 kDa single polypeptides that contain the variable light chain (VL) and...When these molecules, called Bispecific T-cell engagers (BiTE®s), bind CD3 on T cells and a tumor-specific...

...lab Writes a lot of grants Varying degrees of engagement with what happens in the lab Official title is...dedicated to different career options from science policy to science communication and much more. I hope ...

... site and contains the desired edit (or edits) engages the prime editor protein. The prime editor consists...transcriptase domain copies the desired edit, directly polymerizing new DNA onto the nicked target strand. The initial...