Choosing a CRISPR Nuclease: Site Accessibility, Specificity, and Sensitivity
Type
Blog Post
Published
Nov. 5, 2019, 1:28 p.m.
...resulting in a Cas9 with improved specificity. They compared on-site and off-site activity of Sniper-Cas9 to...et al. "Evolved Cas9 variants with broad PAM compatibility and high DNA specificity." Nature 556.7699 (...