Cas13d: Small RNA-targeting CRISPR enzymes for transcriptome engineering
Type
Blog Post
Published
May 3, 2018, 1:48 p.m.
...Konermann et al. Plasmids here
How do Cas13d enzymes compare to other Cas13s?
Like other Cas13 enzymes, the ...cleavage pattern is necessary.
Konermann et al. compared CasRx to multiple RNA regulating methods: small... the clear winner with median knockdown of 96% compared to 65% for shRNA, 53% for CRISPRi, and 66-80% ...Addgene.
Yan, Winston X., et al. “Cas13d Is a Compact RNA-Targeting Type VI CRISPR Effector Positively...