dTAG - You're it!
Type
Blog Post
Published
June 21, 2018, 2:06 p.m.
...proximity with the target protein, leading to polyubiquitination of the target protein and proteasomal degradation...plasmids enable lentiviral expression of N- or C-terminally FKBP12F36V-tagged fusion chimeras or locus-specific...rapid means of comparing functionality of N- and C-terminal fusions and degradation in a cell line of interest...express ENL-FKBP12F36V and endogenous ENL was inactivated using CRISPR/Cas9 gene-editing.
Featured molecules...express FKBP12F36V-MELK and endogenous MELK was inactivated using CRISPR/Cas9 gene-editing.
Featured molecules...