Viral Vectors 101: Systemic Capsids
Type
Blog Post
Published
Oct. 12, 2023, 1:15 p.m.
... 2023
* indicates viral preps available. Mechanisms of crossing the BBB are indicated in parentheses...suitability of a systemic capsid for an individual application is dependent on a number of factors, including...test your chosen capsid before using it in an application.
Figure 1: AAV toolkit for targeted...doses are recommended for all systemic capsid applications. For example, AAV-PHP.eB is typically administered...experimentally determine the best titer for your application.
Pro tip!Want to know if a capsid is a good... capsid immunogenicity is a concern, using a purification method that removes, not just reduces, empty...always, validate the capsid for your specific application and animal model.
Other model organisms
Tropism...