Adapting Toehold Switches to Detect Zika Virus
Type
Blog Post
...validated sensors in as little as one week (Pardee et al, 2016). Using toehold switch-based RNA sensors, our...riboregulators, called toehold switches, which allow for the rational design of RNA sensors that can detect ...the 48 sensors, targeting 24 regions of the genome, we have deposited the best performing sensors and constructs...Zika Sensor Constructs at Addgene
As we report, we have embedded this next generation of toehold switch-based...put in place to provide community protection.
Toehold switches for pathogen detection
In 2014, as postdoctoral...exciting because it enabled gene circuit-based sensors to be used outside of the laboratory. The detection...patient samples (e.g.: blood, urine).
Adapting toehold switches for Zika detection
We and other members...