New Optimized Genome-wide CRISPRko, CRISPRi, and CRISPRa Libraries
Type
Blog Post
...Broad Institute have developed human genome-wide CRISPRko (knock out), CRISPRi (interference), and CRISRPa...The Root and Doench lab’s optimized genome-wide CRISPRko, CRISPRi, and CRISPRa libraries have been shown...optimized human CRISPR libraries.
Brunello: human CRISPRko sgRNA library
The Brunello library consists of...probing a limited number of cells.
Get the Brunello CRISPRko sgRNA library as pooled library or lentiviral ...prep!
Dolcetto: human CRISPRi sgRNA library
While CRISPRko libraries are highly effective at identifying ...genetic screens, they do have several limitations. CRISPRko results in a complete loss of function meaning...have proven their optimized, human genome wide CRISPRko, CRISPRi, and CRISPRa libraries are highly effective...