FLEx Technology and Optogenetics: Flipping the switch on gene expression with high spatial and temporal resolution
Type
Blog Post
...neural activity (Bernstein and Boyden, 2011; Mei and Zhang, 2012). For example, blue light activates channelrhodopsins...excitation, whereas yellow light activates halorhodopsins to silence neuronal activity (Figure 1) (Wiegert et al...targeted cells makes it possible to control neuronal activity with a specificity far greater than the one that...specific wavelengths, selectively turning neuron activity on or off (Atasoy et al., 2008; Taylor et al.,...unclear which subpopulation of DA neurons could activate appetitive rather than aversive stimuli. In a ... this question, mapping and characterizing the activity of the DA neurons of the VTA. Using in vivo optogenetic...genetically targeted optical control of neural activity." Nature neuroscience 8.9 (2005): 1263. PubMed...