We narrowed to 958 results for: OMP;

... It doesn’t have to be this way. We can never completely eliminate the risk that a minor variation in ...Press.  She trained originally in cell biology, completing her PhD at the MRC LMB in Cambridge UK and then... Vice President. Her current responsibilities encompass overall leadership of the Cell Press editorial...

...binds to TIR1 of the SCF-TIR1 ubiquitin ligase complex, promoting its interaction with the degron sequence...used ChRs in that they cause a rapid and almost complete desensitization when exposed to continuous bright...snaking through our cells’ nuclei--our chromatin is comprised of thousands of loops. These loops not only provide...

...responsible for the degradation of over 600 cellular components ultimately leading to cell fragmentation and ...FlipGFP. FlipGFP increases fluorescence 100-fold compared to other reporters (Zhang et al., 2019). How does...and (3) β-strand 11 (β11). Each part contains components and residues that are necessary for fluorescence...

...writing and this recent article published in PLOS Computational Biology (Frassl et al., 2018): “Science is increasingly...collaboratively writing a multi-authored paper. PLoS Comput Biol 14:e1006508 . https://doi.org/10.1371/journal.pcbi...Simple Rules for a Successful Collaboration. PLoS Comput Biol 3:e44 . https://doi.org/10.1371/journal.pcbi...

... I asked participants to read short abstracts comparing the mortality rates between two controversial ...and biased. As a result, the control abstract comparing two fictional medical issues – chronic and acute...community. I brought along printed copies of studies comparing the filtration efficacy of different materials...

...sources. While the importance of understanding these complex processes can’t be overstated, we can also learn...degradation under a variety of conditions. They are composed of 4 proteins encoded in a single operon and were...

...experience using image analysis software. If you use computer programs to predict protein structures, then you... you might know a thing or two about computer modeling. Make sure to focus on these skills. The only exception... into a communications role instead after she completed her MSc in Experimental Medicine. She is the Community...

...than a day. Diagnostic restriction digests are comprised of 2 separate steps: 1) incubating your DNA with... construct. Consider buffer and temperature compatibility when digesting with more than one enzyme. Consult...will allow you to approximate the DNA mass of comparably intense samples of similar size. Run the gel ...

...autoclave. Pro-Tip Once your autoclave cycle is complete, we recommend opening the door to the autoclave...

...proteins >150 kDa. Select Start Run. When the run is complete, select Done. Section 5: Blocking Prepare 1X TBST...

...service supporters We would like to thank the companies who supported this project with funding. Alnylam...donations. That seed money was used to build a completely self-supporting service so that Addgene is not...distribution, this project involved every Addgenie in the company. Our Finance, Business and Legal teams had to pave...

...Paratore onto the Board of Directors brings complementary experience and insight to the now 10 member ... I was interested in what she shared about the company and what the goals were and so I decided to join...time on research. What do you hope Addgene will accomplish in the near future? Katz: I’m excited that Addgene...

...needs to emit a different color of light and be compatible with the lasers available in your microscope ...jRGECO1a and jRCaMP1a are widely used as well. To complement these tools, we recently developed a new orange...1030 nm, enabling two-photon imaging without compromising on brightness, ∆F/F0, or signal-to-noise ratio...

...that use reverse transcriptase to synthesize complementary DNA copies of their genome upon infecting a ...gamma-retrovirus are so closely related, their required components are very similar. While plasmids containing virus-specific...between the two systems, other, more general, viral components such as a heterologous envelope or a post-transcriptional...

...nature, extra safety measures, like replication incompetent viral particles, are required. We will be covering...infect both non-dividing and dividing cells. They accomplish this through nuclear localization signals which... immunodeficiency virus type 1 preintegration complexes.” Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 6580...

...However, one of the many proteins which are not compatible with regular mesophilic systems are the psychrophilic...chaperones protein resulted in higher levels of growth compared to the E. coli strain expressing the empty vector... Medal in the Undergrad category at the iGEM Competition 2019. He has an active interest in scientific...

...to start a more formal mentoring program at my company, but there weren't enough senior people willing... such as pre-reads, videos or exercises to be completed in preparation for the meeting or to be read or... and help each other practice meeting people – compete for fastest to set up a coffee date or most cards...

... had been collecting data and documenting the compliance of universities with the FLSA in our online resource... salary raising as the only viable option for compliance. However, 10 days prior to the implementation...opportunity of the lapsed mandate (or are being compelled at the state level, in the case of some public...

...validated their platform on clinical stool samples by comparison to qPCR and demonstrated that it can also detect...without fixation or preparation, and deliver CRISPR components for gene disruption or CRISPRi. While designed...bacteriophage shell protein or a bacterial microcompartment protein. The expression of this fusion is ...

... light sensitive and have enhanced conductance compared to current channelrhodopsins. Their new channelrhodopsins...neurons do not express as many copies of the ChRs as compared to direct injection. This lower multiplicity of...better suited for systemic delivery with PHP.eB compared to the existing ChR2(H134R).  In the second experiment...