We narrowed to 601 results for: sam

1. Quick Guide to Near-Infrared Fluorescent Proteins

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   Blog Post

   ..., and deep penetration of red-shifted light. The same NIR FPs and biosensors can be imaged at spatial ...

2. Adeno-associated Viruses (AAVs) for Genome Editing

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   ...require modifying multiple genes simultaneously in the same cell, are more appropriate for a CRISPR-based approach...

3. Treating Muscular Dystrophy with CRISPR Gene Editing

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   ...slightly different methods, they each observed the same positive phenotypes in cardiac and skeletal muscle...

4. Thoughts on the Future of Research 2015 Boston Symposium

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   ...underrepresented groups under their mentorship with the same critical eye they place on others within their labs...

5. Evolution of Brainbow: Using Cre-lox for Multicolor Labeling of Neurons

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   ...three loxP variants, but the principles remain the same. The first fluorescent protein in the construct,...

6. Plasmids 101: Common Lab E. coli Strains

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   ...convoluted due to researchers sharing and renaming samples throughout history. It was likely isolated in 1918...

7. CRISPR 101: Off-Target Effects

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   ...If you are performing CRISPR library screens, the same principle holds true - the higher the number of ...

8. Viral Vectors 101: Optogenetic Tools

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   ...one cell type to another, as they may not use the same pathways. Additionally, as GPCR signaling is amplified...

9. Hot Plasmids: Spring 2025

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   ...proteoglycans composed of a protein core, 2–4 glycosaminoglycans (GAG), and are (typically) tethered to the...

10. CRISPR 101: Epigenetics and Editing the Epigenome

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    ...activate transcription. A lentiviral vector with the same modifier, Fuw-dCas9-Tet1CD, is available from Rudolf...

11. Easi-CRISPR: Generating Knock-In and Conditional Mouse Models

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    ...They have successfully used guides targeting the same or complementary strands, as well as guides facing...

12. Finding Your Perfect Job After University

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    ...cancer and I loved the practical aspects of testing samples in the lab, but I really struggled with the large...

13. Building Global Connections with the International Mentorship Program USA-EUROPE

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    ... my mentor, since she does research at UK in the same field that I do: prostate cancer. She has guided...

14. Tips for a 1st Time CRISPR User (by a 1st Time CRISPR User)

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    Blog Post

    ... bottom of the gel in the BRAF gRNA-transduced samples (data not shown). Pro-Tips: 1.Designing primers...

15. Sequencing Options for CRISPR Genotyping

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    ...investigator can be relatively certain that their samples don’t have off-target mutations if they remain ...

16. An “elegans” Approach to Better CRISPR/Cas9 Editing Efficiency

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    ...changes 5’ to the PAM, sequences corresponding to the same strand as the PAM produced a higher editing efficiency...

17. RNA Interference in Plant Biology: New Tools for an Old Favorite

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    ...between gene silencing and knockout methods of the same gene. However, recent work has called this prevalent...

18. A History of Genome Engineering in Popular Culture

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    Blog Post

    ...findings of the 1952 Hershey-Chase experiment. In the same year, Rosalind Franklin and her student Raymond ...

19. Cancer and the Immune System: Deciphering the Relationship

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    Blog Post

    ...multiple immunotherapy targets can be utilized at the same time. A combination of tolerance marker blockade...

20. Plasmids 101: Modular Cloning Applications and Kits

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    ...unique genomic targets or multiple sgRNAs against the same target to ensure efficient cutting. Beyond sgRNAs...