We narrowed to 610 results for: sam

1. Adeno-associated Viruses (AAVs) for Genome Editing

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   ...require modifying multiple genes simultaneously in the same cell, are more appropriate for a CRISPR-based approach...

2. March for Science

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   ...politician Rush Holt said, government must have the same fundamental attribute that enables science: “humility...

3. The Advances Behind The World's First Personalized CRISPR Treatment

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   ...changes, meaning the new codon corresponded to the same amino acid. Thus, bystander editing was deemed to...

4. Viral Vectors 101: Integrase-Deficient Lentiviral Vectors

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   ...performing quantitative PCR titration of vector DNA in samples harvested 24 hours post-transduction (Wanisch and...

5. Hot Biosensors 2022: Year-End Roundup

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   ...to the range of concentrations expected in your samples. Higher affinity isn’t always better, especially...

6. Quick Guide to Near-Infrared Fluorescent Proteins

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   ..., and deep penetration of red-shifted light. The same NIR FPs and biosensors can be imaged at spatial ...

7. New Optogenetic Tools for Cytoskeleton and Membrane Control

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   ...microtubule-severing protein, Katanin is of course named for the samurai sword called a katana. Opto-katanin consists of...

8. CRISPR 101: Homology Directed Repair

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   ... occur; however, if both HJs are resolved in the same manner, this results in a non-crossover event.  ...

9. Plasmids 101: Biotinylation

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   ...pre-incubated with free avidin can be added to your sample. Any free biotin-binding sites on this complex ...

10. Multiple Plasmids at a Low Price: Kits from Addgene

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    ...plasmids used to generate these fusions all use the same restriction enzymes for cloning. Furthermore, some...

11. 10 Steps to a Perfect Science Talk

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    ... it perfectly fits the occasion.  I speak on the same topics many times, but I always seek out information...

12. Treating Muscular Dystrophy with CRISPR Gene Editing

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    ...slightly different methods, they each observed the same positive phenotypes in cardiac and skeletal muscle...

13. Thoughts on the Future of Research 2015 Boston Symposium

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    ...underrepresented groups under their mentorship with the same critical eye they place on others within their labs...

14. Evolution of Brainbow: Using Cre-lox for Multicolor Labeling of Neurons

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    ...three loxP variants, but the principles remain the same. The first fluorescent protein in the construct,...

15. Plasmids 101: Common Lab E. coli Strains

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    ...convoluted due to researchers sharing and renaming samples throughout history. It was likely isolated in 1918...

16. Easi-CRISPR: Generating Knock-In and Conditional Mouse Models

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    ...They have successfully used guides targeting the same or complementary strands, as well as guides facing...

17. CRISPR 101: Epigenetics and Editing the Epigenome

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    ...activate transcription. A lentiviral vector with the same modifier, Fuw-dCas9-Tet1CD, is available from Rudolf...

18. Hot Plasmids: Spring 2025

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    ...proteoglycans composed of a protein core, 2–4 glycosaminoglycans (GAG), and are (typically) tethered to the...

19. CRISPR 101: Off-Target Effects

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    ...If you are performing CRISPR library screens, the same principle holds true - the higher the number of ...

20. Viral Vectors 101: Optogenetic Tools

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    ...one cell type to another, as they may not use the same pathways. Additionally, as GPCR signaling is amplified...