We narrowed to 5 results for: ung

...introduced its opposite, a uracil DNA N-glycosylase (UNG) from E. coli. The resulting construct, eUNG-BE4max...Editor, or GBE, for its reliance on the glycosylase UNG to crease abasic sites (Zhao et al., 2021). Their...processes. Created with BioRender.com. Beyond UNG: Optimizing C → G editors Now that several labs had...mechanism: cytidine deaminase converts C to U, and UNG excises the new U to create an abasic site. But how... repair proteins fused to CGBEs Instead of using UNG, the Wei Leong Chew Lab developed two fusions of ...Yuan et al., 2021). In addition, they showed that UNG from both E. coli and C. elegans could be effective...team also demonstrated that different deaminase and UNG enzymes had different sequence preferences, which...

...either fused or endogenous Uracil DNA N-glycosylase (UNG) enzymes. Various other proteins included in different...guanosine instead, perhaps analogous engineering of UNG, which excises uracil, could allow it to recognize... et al., 2024; Yi et al., 2024). In each case, a UNG enzyme was modified to recognize T and/or C substrates...Also called an apurinic / apyrimidinic (AP) site. UNG / UDG Uracil DNA N-Glycosylase Removes uracil from...

...uracil N-glycosylase (UNG) during base excision repair. Adding a second copy of the UNG inhibitor, UGI, increases...