CRISPR 101: Anti-CRISPR Proteins Switch Off CRISPR-Cas Systems
Type
Blog Post
...How do anti-CRISPR proteins work?
Anti-CRISPRs proteins are highly diverse but most block CRISPR activity...proteins.
Discovery of anti-CRISPR proteins
That is, until the discovery of anti-CRISPR proteins in 2012 (...al., 2012). Anti-CRISPR (Acr) proteins are phage-derived small protein inhibitors of CRISPR-Cas systems...Since these early anti-CRISPR studies, scientists have discovered over 50 anti-CRISPR proteins that interact...
A note on anti-CRISPR nomenclature
Acr family proteins are named for the type of CRISPR-Cas system they...al., 2017).
Figure 1: Anti-CRISPR proteins (Acr's) can block CRISPR activity in many ways such as... type II-A CRISPR-Cas systems. A full list of Acr proteins organized by the type of CRISPR-Cas system ...