Addgene

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ACER

Pooled Library

#226117

Purpose

The Advanced Catalogue of Epigenetic Regulators (ACER) library allows scientists to study how different epigenetic proteins influence gene activity and contribute to diseases.

Depositor

Rui Lu

Article

Zhou et al Blood. 2024 Aug 16:blood.2023023644. doi

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Oct. 29, 2024

Availability

Academic Institutions and Nonprofits only
Bassik lab Human CRISPR-Cas9 Deletion Library - Apoptosis and cancer

Pooled Library

#101926

Purpose

Bassik lab Human CRISPR-Cas9 Deletion Library - Apoptosis and cancer. Coexpresses mCherry.

Depositor

Michael Bassik

Article

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

Expression

Mammalian

Use

CRISPR

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
Bassik lab Human CRISPR-Cas9 Deletion Library - Gene Expression

Pooled Library

#101928

Purpose

Bassik lab Human CRISPR-Cas9 Deletion Library - Gene Expression. Coexpresses mCherry.

Depositor

Michael Bassik

Article

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

Expression

Mammalian

Use

CRISPR

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
Bassik lab Human CRISPR-Cas9 Deletion Library - Proteostasis

Pooled Library

#101930

Purpose

Bassik lab Human CRISPR-Cas9 Deletion Library - Proteostasis. Coexpresses mCherry.

Depositor

Michael Bassik

Article

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

Expression

Mammalian

Use

CRISPR

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned3

Pooled Library

#101934

Purpose

Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned3. Coexpresses mCherry.

Depositor

Michael Bassik

Article

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

Expression

Mammalian

Use

CRISPR

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned2

Pooled Library

#101933

Purpose

Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned2. Coexpresses mCherry.

Depositor

Michael Bassik

Article

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

Expression

Mammalian

Use

CRISPR

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
BARBEKO sgRNA library

Pooled Library

#174163

Purpose

iBARed cytosine Base Editing-mediated gene KnockOut (BARBEKO) sgRNA library; This library leverages CRISPR cytosine base editors for genome-scale knockout screens.

Depositor

Wensheng Wei

Article

Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Aug. 31, 2021

Availability

Academic Institutions and Nonprofits only
Oxford Drosophila melanogaster Genome-wide CRISPR Library

Pooled Library

#64750

Purpose

A genome-wide CRISPR library covering 13,501 genes (98.8% of the Drosophila melanogaster genome), among which 8,989 genes are targeted by three or more independent single guide RNAs (sgRNAs).

Depositor

Ji-Long Liu

Article

Bassett et al J Genet Genomics. 2015 Jun 20;42(6):301-

Expression

Insect

Species

Drosophila melanogaster, Streptococcus pyogenes, and Synthetic

Use

CRISPR

Available since

March 7, 2016

Availability

Academic Institutions and Nonprofits only
CHyMErA Exon-deletion hgRNA Library

Pooled Library

#155200

Purpose

Hybrid guide RNA library targeting human alternative cassette exons for deletion and disruption

Depositor

Benjamin Blencowe, Jason Moffat

Article

Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Sept. 2, 2020

Availability

Academic Institutions and Nonprofits only
CHyMErA Paralog&Dual-targeting hgRNA Library

Pooled Library

#155199

Purpose

Hybrid guide RNA library targetings human paralog pairs and other protein-coding genes.

Depositor

Benjamin Blencowe, Jason Moffat

Article

Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Sept. 2, 2020

Availability

Academic Institutions and Nonprofits only
Ma-PylRS-lib1

Pooled Library

#224585

Purpose

Pyrrolysine tRNA synthetase library to generate new genetic code expansion (GCE) systems for site-specific incorporation of non-canonical amino acids (ncAAs) into proteins.

Depositor

Ryan Mehl

Article

Avila-Crump et al ACS Chem Biol. 2022 Dec 16;17(12):3458-3

Expression

Bacterial

Species

Methanomethylophilus alvus

Available since

Jan. 6, 2025

Availability

Academic Institutions and Nonprofits only
Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases

Pooled Library

#101927

Purpose

Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases. Coexpresses mCherry.

Depositor

Michael Bassik

Article

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

Expression

Mammalian

Use

CRISPR

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
Bassik lab Human CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility

Pooled Library

#101931

Purpose

Bassik lab Human CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility. Coexpresses mCherry.

Depositor

Michael Bassik

Article

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

Expression

Mammalian

Use

CRISPR

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
Human SLC KO Library

Pooled Library

#132552

Purpose

Expresses gRNAs for knockout of the human Solute Carrier family

Depositor

Giulio Superti-Furga

Article

Girardi et al Nat Chem Biol. 2020 Apr;16(4):469-478. d

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

May 7, 2020

Availability

Academic Institutions and Nonprofits only
Human SLC SAM Library

Pooled Library

#132561

Purpose

Expresses gRNAs for activation of human Solute Carrier family genes

Depositor

Giulio Superti-Furga

Article

Rebsamen et al Life Sci Alliance. 2022 Sep 16;5(11):e20

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

May 18, 2020

Availability

Academic Institutions and Nonprofits only
TP53 MITE Library

Pooled Library

#113569

Purpose

Pooled lentiviral plasmid library containing ~8,000 single amino acid substitution and nonsense mutant variants of p53

Depositor

David Root, William Hahn

Article

Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available since

Jan. 4, 2019

Availability

Academic Institutions and Nonprofits only
MYC-CRISPR

Pooled Library

#173195

Purpose

This pooled lentiviral CRISPR knockout library targets E-boxes genome-wide and can be applied for identification of essential MYC binding sites in a wide range of human cells.

Depositor

Agnieszka Dzikiewicz-Krawczyk

Article

Kazimierska et al Mol Oncol. 2023 Nov;17(11):2295-2313. do

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Aug. 11, 2021

Availability

Academic Institutions and Nonprofits only
Liu Lab MusCK Library A

Pooled Library

#174196

Purpose

MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK A contains 5 gRNAs per gene.

Depositor

Xiaole Shirley Liu

Article

Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Oct. 29, 2021

Availability

Academic Institutions and Nonprofits only
Liu Lab MusCK Library B

Pooled Library

#174197

Purpose

MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK M_b contains 5 gRNAs per gene.

Depositor

Xiaole Shirley Liu

Article

Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Oct. 29, 2021

Availability

Academic Institutions and Nonprofits only
HR700_TP53Exon5mut

Pooled Library

#229137

Purpose

Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 5 of human cells via CRISPR-HDR.

Depositor

Thorsten Stiewe

Article

Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Cre/Lox

Available since

Feb. 24, 2025

Availability

Industry, Academic Institutions, and Nonprofits

Showing: 121 - 140 of 149 results

Results per page:

Sort results by:

ACER

Bassik lab Human CRISPR-Cas9 Deletion Library - Apoptosis and cancer

Bassik lab Human CRISPR-Cas9 Deletion Library - Gene Expression

Bassik lab Human CRISPR-Cas9 Deletion Library - Proteostasis

Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned3

Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned2

BARBEKO sgRNA library

Oxford Drosophila melanogaster Genome-wide CRISPR Library

CHyMErA Exon-deletion hgRNA Library

CHyMErA Paralog&Dual-targeting hgRNA Library

Ma-PylRS-lib1

Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases

Bassik lab Human CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility

Human SLC KO Library

Human SLC SAM Library

TP53 MITE Library

MYC-CRISPR

Liu Lab MusCK Library A

Liu Lab MusCK Library B

HR700_TP53Exon5mut

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