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Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set B

Pooled Library

#92380

Purpose

CRISPRa

Depositor

David Root, John Doench

Article

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

Use

Lentiviral

Available since

Aug. 3, 2017

Availability

Academic Institutions and Nonprofits only
Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF), Set B

Pooled Library

#92384

Purpose

CRISPRa

Depositor

David Root, John Doench

Article

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

July 13, 2018

Availability

Academic Institutions and Nonprofits only
Human sgRNA library Brunello in lentiGuide-Puro

Pooled Library

#73178

Purpose

Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
Human sgRNA library Brunello in lentiCRISPRv2

Pooled Library

#73179

Purpose

Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
Mouse sgRNA library Brie in lentiCRISPRv2

Pooled Library

#73632

Purpose

Mouse sgRNA library in backbone lentiCRISPRv2 containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 25, 2016

Availability

Academic Institutions and Nonprofits only
Mouse sgRNA library Brie in lentiGuide-Puro

Pooled Library

#73633

Purpose

Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 25, 2016

Availability

Academic Institutions and Nonprofits only
Lenti-human-TF-gRNA-puromycin

Pooled Library

#162275

Purpose

This is a gRNA library targeting on ~1600 human transcription factors for genetic screening.

Depositor

Chunliang Li

Article

Zhang et al Elife. 2020 Oct 1;9. pii: 57858. doi: 10

Species

Homo sapiens

Use

Lentiviral

Available since

Dec. 15, 2020

Availability

Academic Institutions and Nonprofits only
Human Lipid Droplet and Metabolism Library

Pooled Library

#191535

Purpose

Lentiviral CRISPR library targeting 1,196 genes related to lipid droplet biology and cell metabolism.

Depositor

James Olzmann

Article

Roberts et al Dev Cell. 2023 Jul 18:S1534-5807(23)0033

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

March 1, 2023

Availability

Academic Institutions and Nonprofits only
Mouse Brie kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

Pooled Library

#75317

Purpose

Mouse sgRNA library in backbone lentiCRISPRv2 targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Available since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
Mouse Brie kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

Pooled Library

#75316

Purpose

Mouse sgRNA library in backbone lentiGuide-Puro targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Available since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
Human Brunello kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

Pooled Library

#75314

Purpose

Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
Human Brunello kinome pooled library, guides 5-8 in lentiCRISPRv2 backbone

Pooled Library

#75315

Purpose

Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
CHyMErA Exon-deletion hgRNA Library

Pooled Library

#155200

Purpose

Hybrid guide RNA library targeting human alternative cassette exons for deletion and disruption

Depositor

Benjamin Blencowe, Jason Moffat

Article

Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Sept. 2, 2020

Availability

Academic Institutions and Nonprofits only
CHyMErA Paralog&Dual-targeting hgRNA Library

Pooled Library

#155199

Purpose

Hybrid guide RNA library targetings human paralog pairs and other protein-coding genes.

Depositor

Benjamin Blencowe, Jason Moffat

Article

Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Sept. 2, 2020

Availability

Academic Institutions and Nonprofits only
Human Brunello kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

Pooled Library

#75312

Purpose

Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
MYC-CRISPR

Pooled Library

#173195

Purpose

This pooled lentiviral CRISPR knockout library targets E-boxes genome-wide and can be applied for identification of essential MYC binding sites in a wide range of human cells.

Depositor

Agnieszka Dzikiewicz-Krawczyk

Article

Kazimierska et al Mol Oncol. 2023 Nov;17(11):2295-2313. do

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Aug. 11, 2021

Availability

Academic Institutions and Nonprofits only
Human Brunello kinome pooled library, guides 5-8 in lentiGuide-Puro backbone

Pooled Library

#75313

Purpose

Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

Depositor

David Root, John Doench

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
Human ubiquitination-related proteins CRISPR KO library

Pooled Library

#174592

Purpose

CRISPR Cas9 KO library targets 660 ubiquitination-related proteins, including all major E1, E2, E3 and deubiquitinating enzymes, as well as other ubiquitination-related proteins.

Depositor

Juan Bonifacino

Article

Jia et al Elife. 2019 Nov 6;8. pii: 50034. doi: 10

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Nov. 30, 2021

Availability

Academic Institutions and Nonprofits only
Human Transporter Knockout library

Pooled Library

#213695

Purpose

Next generation transporter-focused CRISPR/Cas9 library targeting transmembrane transporters to test the impact of transporters on biological processes.

Depositor

RESOLUTE Consortium, Giulio Superti-Furga

Article

Ferdigg et al Life Sci Alliance. 2024 Nov 22;8(2):e202

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Sept. 13, 2024

Availability

Academic Institutions and Nonprofits only
p11-3’_8xN_PAM-site1 (RTW554)

Pooled Library

#160132

Purpose

Plasmid library harboring a randomized 8nt PAM 3’ of target site 1. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

Depositor

Benjamin Kleinstiver, Keith Joung

Article

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Species

Synthetic

Use

CRISPR

Available since

Feb. 8, 2021

Availability

Academic Institutions and Nonprofits only

Showing: 41 - 60 of 70 results

Results per page:

Sort results by:

Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set B

Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF), Set B

Human sgRNA library Brunello in lentiGuide-Puro

Human sgRNA library Brunello in lentiCRISPRv2

Mouse sgRNA library Brie in lentiCRISPRv2

Mouse sgRNA library Brie in lentiGuide-Puro

Lenti-human-TF-gRNA-puromycin

Human Lipid Droplet and Metabolism Library

Mouse Brie kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

Mouse Brie kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

Human Brunello kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

Human Brunello kinome pooled library, guides 5-8 in lentiCRISPRv2 backbone

CHyMErA Exon-deletion hgRNA Library

CHyMErA Paralog&Dual-targeting hgRNA Library

Human Brunello kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

MYC-CRISPR

Human Brunello kinome pooled library, guides 5-8 in lentiGuide-Puro backbone

Human ubiquitination-related proteins CRISPR KO library

Human Transporter Knockout library

p11-3’_8xN_PAM-site1 (RTW554)

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