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Mouse Toronto KnockOut (mTKO) CRISPR Library - pLCKO2

Pooled Library

#159393

Purpose

Mouse lentiviral genome-wide CRISPR library

Depositor

Jason Moffat

Article

Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Nov. 9, 2020

Availability

Academic Institutions and Nonprofits only
Mouse Toronto KnockOut (mTKO) CRISPR Library - lentiCRISPRv2

Pooled Library

#159392

Purpose

Mouse lentiviral genome-wide CRISPR library

Depositor

Jason Moffat

Article

Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Nov. 9, 2020

Availability

Academic Institutions and Nonprofits only
Mouse Validation (mVAL) CRISPR Library

Pooled Library

#159391

Purpose

Pooled CRISPR library targets core intrinsic immune evasion genes

Depositor

Jason Moffat

Article

Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Nov. 9, 2020

Availability

Academic Institutions and Nonprofits only
pre-associated oBC-minP-GFP-mBC backbone (p043)

Pooled Library

#194098

Purpose

pre-associated oBC-minP-GFP-mBC backbone (p043), can directly be used to deposit library of regulatory elements

Depositor

Jay Shendure

Article

Lalanne et al bioRxiv 2022.12.10.519236

Expression

Bacterial and Mammalian

Use

RNAi

Available since

April 3, 2024

Availability

Academic Institutions and Nonprofits only
Human Paralog Knockout Library (pgPEN)

Pooled Library

#171172

Purpose

CRISPR library targets human duplicate paralog gene pairs

Depositor

Alice Berger

Article

Parrish et al Cell Rep. 2021 Aug 31;36(9):109597. doi:

Expression

Mammalian

Species

Homo sapiens and Synthetic

Use

CRISPR and Lentiviral

Available since

Sept. 28, 2021

Availability

Academic Institutions and Nonprofits only
Mode #1 Library

Pooled Library

#111704

Purpose

Encodes GST-fused human phosphopeptides

Depositor

Jesse Rinehart

Article

Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

Expression

Bacterial

Species

Homo sapiens

Available since

Dec. 1, 2022

Availability

Academic Institutions and Nonprofits only
Mode #2 Library (NEDD4 WW2 domain)

Pooled Library

#111707

Purpose

Encodes NEDD4 WW2 domain and human phosphopeptides fused to split mCherry for Hi-P

Depositor

Jesse Rinehart

Article

Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

Expression

Bacterial

Species

Homo sapiens

Available since

Dec. 1, 2022

Availability

Academic Institutions and Nonprofits only
Mode #2 Library (14-3-3σ)

Pooled Library

#111706

Purpose

Encodes 14-3-3σ and human phosphopeptides fused to split mCherry for Hi-P

Depositor

Jesse Rinehart

Article

Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

Expression

Bacterial

Species

Homo sapiens

Available since

Dec. 1, 2022

Availability

Academic Institutions and Nonprofits only
Mode #2 Library (14-3-3β)

Pooled Library

#111705

Purpose

Encodes 14-3-3β and human phosphopeptides fused to split mCherry for Hi-P

Depositor

Jesse Rinehart

Article

Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

Expression

Bacterial

Species

Homo sapiens

Available since

Dec. 1, 2022

Availability

Academic Institutions and Nonprofits only
pRG01-MCAP_MET

Pooled Library

#123361

Purpose

pRG01 with barcoded MCAP_Met crRNA array library cloned in, targeting combinations of metastasis drivers.

Depositor

Sidi Chen

Article

Chow et al Nat Methods. 2019 May;16(5):405-408. doi

Expression

Mammalian

Species

Synthetic

Use

CRISPR and Lentiviral

Available since

June 10, 2019

Availability

Academic Institutions and Nonprofits only
pRep-Cap Scanning Saturation Mutagenesis (SSM) pooled library

Pooled Library

#199601

Purpose

pRep-Cap SSM library enables VP1, VP2, and VP3 expression under the control of the endogenous p40 promoter

Depositor

George Church

Article

Ogden et al Science. 2019 Nov 29;366(6469):1139-1143

Expression

Mammalian

Species

Aav2

Use

AAV

Available since

June 13, 2023

Availability

Academic Institutions and Nonprofits only
Human Whole Genome sgRNA iBAR Library

Pooled Library

#140633

Purpose

CRISPR pooled screen at high MOI by the embedded internal barcodes

Depositor

Wensheng Wei

Article

Zhu et al Genome Biol. 2019 Jan 24;20(1):20. doi:

Use

CRISPR and Lentiviral

Available since

April 21, 2020

Availability

Academic Institutions and Nonprofits only
Mode #2 Library (NEDD4-2 WW2 domain)

Pooled Library

#111708

Purpose

Encodes NEDD4-2 WW2 domain and human phosphopeptides fused to split mCherry for Hi-P

Depositor

Jesse Rinehart

Article

Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

Expression

Bacterial

Species

Homo sapiens

Available since

Dec. 1, 2022

Availability

Academic Institutions and Nonprofits only
Mini-human AsCpf1-based human genome-wide knockout library

Pooled Library

#130630

Purpose

Expresses crRNAs for genome-wide knockout pooled library screening

Depositor

Giulio Draetta

Article

Liu et al Nat Commun. 2019 Jul 17;10(1):3144. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Sept. 9, 2019

Availability

Academic Institutions and Nonprofits only
Lourido Toxoplasma CRISPR Library V1

Pooled Library

#80636

Purpose

Plasmid sgRNA library containing ten guides against each of the 8,158 predicted Toxoplasma gondii protein coding genes.

Depositor

Sebastian Lourido

Article

Sidik et al Cell. 2016 Sep 8;166(6):1423-1435.e12. d

Available since

Sept. 19, 2016

Availability

Academic Institutions and Nonprofits only
EFS-mTSG

Pooled Library

#113584

Purpose

AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes

Depositor

Sidi Chen

Article

Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

Expression

Mammalian

Use

AAV, CRISPR, Lentiviral, and Luciferase

Available since

July 23, 2019

Availability

Academic Institutions and Nonprofits only
mTORC1 Focused library

Pooled Library

#164084

Purpose

Lentiviral CRISPR library targets human mTORC1 signaling pathway

Depositor

David Sabatini

Article

Condon et al Proc Natl Acad Sci U S A. 2021 Jan 26;11

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Jan. 11, 2021

Availability

Academic Institutions and Nonprofits only
The Human Druggable CRISPR library

Pooled Library

#200013

Purpose

The library contains ~10,000 sgRNAs targeting 1,980 human genes (5 sgRNAs per gene and 100 nontargeting control sgRNAs).

Depositor

Lianxin Liu

Article

Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

May 9, 2023

Availability

Academic Institutions and Nonprofits only
MORF library without GFP and mCherry controls

Pooled Library

#192821

Purpose

Barcoded transcription factor ORF library for high throughput screening

Depositor

Feng Zhang

Article

Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available since

Jan. 11, 2023

Availability

Academic Institutions and Nonprofits only
Human Genome-wide Intron Tagging Library, Frame 1

Pooled Library

#216134

Purpose

Library of intron-targeting sgRNAs for pooled tagging of proteins with GFP or other protein tags at their endogenous genomic locus using an intron tagging approach.

Depositor

Stefan Kubicek

Article

Reicher et al Nat Cell Biol. 2024 May;26(5):745-756. d

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

April 19, 2024

Availability

Academic Institutions and Nonprofits only

Showing: 41 - 60 of 105 results

Results per page:

Sort results by:

Mouse Toronto KnockOut (mTKO) CRISPR Library - pLCKO2

Mouse Toronto KnockOut (mTKO) CRISPR Library - lentiCRISPRv2

Mouse Validation (mVAL) CRISPR Library

pre-associated oBC-minP-GFP-mBC backbone (p043)

Human Paralog Knockout Library (pgPEN)

Mode #1 Library

Mode #2 Library (NEDD4 WW2 domain)

Mode #2 Library (14-3-3σ)

Mode #2 Library (14-3-3β)

pRG01-MCAP_MET

pRep-Cap Scanning Saturation Mutagenesis (SSM) pooled library

Human Whole Genome sgRNA iBAR Library

Mode #2 Library (NEDD4-2 WW2 domain)

Mini-human AsCpf1-based human genome-wide knockout library

Lourido Toxoplasma CRISPR Library V1

EFS-mTSG

mTORC1 Focused library

The Human Druggable CRISPR library

MORF library without GFP and mCherry controls

Human Genome-wide Intron Tagging Library, Frame 1

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