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TRE-MPRA_minPromega Library

Pooled Library

#201013

Purpose

Massively parallel reporter assay (MPRA) library with minPromega promoter

Depositor

Justin English

Article

Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

Expression

Mammalian

Use

Luciferase

Available since

Oct. 31, 2023

Availability

Academic Institutions and Nonprofits only
The Human Druggable CRISPR library

Pooled Library

#200013

Purpose

The library contains ~10,000 sgRNAs targeting 1,980 human genes (5 sgRNAs per gene and 100 nontargeting control sgRNAs).

Depositor

Lianxin Liu

Article

Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

May 9, 2023

Availability

Academic Institutions and Nonprofits only
Human CRISPR Poison Exon Knockout Library

Pooled Library

#138084

Purpose

The human pgPoison library induces skipping of “poison” cassette exons and corresponding upstream constitutive exons by targeting 3' splice sites with paired gRNAs (pgRNAs).

Depositor

Robert Bradley

Article

Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

March 6, 2020

Availability

Academic Institutions and Nonprofits only
Liu Lab MusCK Library A

Pooled Library

#174196

Purpose

MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK A contains 5 gRNAs per gene.

Depositor

Xiaole Shirley Liu

Article

Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Oct. 29, 2021

Availability

Academic Institutions and Nonprofits only
Liu Lab MusCK Library B

Pooled Library

#174197

Purpose

MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK M_b contains 5 gRNAs per gene.

Depositor

Xiaole Shirley Liu

Article

Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Oct. 29, 2021

Availability

Academic Institutions and Nonprofits only
Wei lab paired-guide RNA (pgRNA) CRISPR–Cas9 library for human long non-coding RNAs (lncRNAs)

Pooled Library

#89640

Purpose

Paired sgRNA library containing 12,472 pgRNAs targeting 671 human long non-coding RNAs (lncRNAs)

Depositor

Wensheng Wei

Article

Zhu et al Nat Biotechnol. 2016 Dec;34(12):1279-128

Expression

Mammalian

Use

Lentiviral

Available since

May 17, 2017

Availability

Academic Institutions and Nonprofits only
RLC11

Pooled Library

#163955

Purpose

RLC11 pooled library

Depositor

Jeremy Rock

Article

Bosch et al Cell. 2021 Jul 16. pii: S0092-8674(21)00

Expression

Bacterial

Use

CRISPR

Available since

Oct. 1, 2021

Availability

Academic Institutions and Nonprofits only
DDR_MKOv4

Pooled Library

#140219

Purpose

CRISPR DNA damage response library

Depositor

Junjie Chen

Article

Su et al DNA Repair (Amst). 2020 Jan 16;87:102803

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Aug. 20, 2021

Availability

Academic Institutions and Nonprofits only
RLC12

Pooled Library

#163954

Purpose

RLC12 pooled library

Depositor

Jeremy Rock

Article

Bosch et al Cell. 2021 Jul 16. pii: S0092-8674(21)00

Expression

Bacterial

Use

CRISPR

Available since

Oct. 1, 2021

Availability

Academic Institutions and Nonprofits only
Humagne Set C

Pooled Library

#172650

Purpose

Set C contains best-ranked guides 1 and 4.

Depositor

David Root, John Doench

Article

DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

Expression

Mammalian

Available since

Nov. 10, 2021

Availability

Academic Institutions and Nonprofits only
Humagne Set D

Pooled Library

#172651

Purpose

Set D contains best-ranked guides 2 and 3.

Depositor

David Root, John Doench

Article

DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

Expression

Mammalian

Available since

Nov. 10, 2021

Availability

Academic Institutions and Nonprofits only
Pan-cancer CasRx lncRNA Albarossa library

Pooled Library

#212966

Purpose

The human CasRx CRISPR lentiviral library encodes 75,725 gRNA arrays (two gRNAs per array) targeting 24,171 lncRNAs.

Depositor

Roland Rad

Article

Montero et al Nat Methods. 2024 Feb 26. doi: 10.1038/s

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 21, 2024

Availability

Academic Institutions and Nonprofits only
SPECS library

Pooled Library

#127842

Purpose

For performing high-throughput cell state-specific synthetic promoter screening

Depositor

Timothy Lu

Article

Wu et al Nat Commun. 2019 Jun 28;10(1):2880. doi:

Species

Synthetic

Use

Lentiviral

Available since

Aug. 22, 2020

Availability

Academic Institutions and Nonprofits only
S. rosetta Col- cDNA amplified library

Pooled Library

#62843

Purpose

amplified library of Salpingoeca rosetta

Depositor

Nicole King

Article

Fairclough et al Genome Biol. 2013 Feb 18;14(2):R15. doi:

Expression

Bacterial

Species

Salpingoeca rosetta

Available since

June 16, 2015

Availability

Academic Institutions and Nonprofits only
hCRISPRi_dual_1_2

Pooled Library

#187246

Purpose

Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

Depositor

Jonathan Weissman, Marco Jost

Article

Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

Species

Synthetic

Use

Lentiviral

Available since

Sept. 30, 2022

Availability

Academic Institutions and Nonprofits only
hCRISPRi_dual_3_4

Pooled Library

#187247

Purpose

Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

Depositor

Jonathan Weissman, Marco Jost

Article

Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

Species

Synthetic

Use

Lentiviral

Available since

Sept. 30, 2022

Availability

Academic Institutions and Nonprofits only
Pan-Druggable Cancer Library

Pooled Library

#182133

Purpose

All-in-one CRISPR/Cas system with 74 individual elements. 63 elements target cancer-related genes with FDA-approved drug treatments, and 3 elements target key medulloblastoma driver genes.

Depositor

Prashant Mali

Article

Hu et al Biomaterials. 2022 Jan;280:121276. doi:

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Aug. 26, 2022

Availability

Academic Institutions and Nonprofits only
hCRISPRa_dual_1_2

Pooled Library

#187249

Purpose

Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

Depositor

Jonathan Weissman, Marco Jost

Article

Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

Species

Synthetic

Use

Lentiviral

Available since

Sept. 30, 2022

Availability

Academic Institutions and Nonprofits only
Mouse Cardiac Transcriptional Regulators CRISPR Knockout Library

Pooled Library

#138015

Purpose

This library can be used to investigate cardiac gene regulation. It targets transcriptional regulators that are expressed in mouse cardiomyocytes. A subset of GATA4 regulated genes are also included.

Depositor

William Pu

Article

VanDusen et al bioRxiv 2019, 808402v1; doi: https://doi

Species

Mus musculus

Use

AAV, CRISPR, and Cre/Lox

Available since

April 17, 2020

Availability

Academic Institutions and Nonprofits only
hCRISPRa_dual_3_4

Pooled Library

#187250

Purpose

Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

Depositor

Jonathan Weissman, Marco Jost

Article

Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

Species

Synthetic

Use

Lentiviral

Available since

Sept. 30, 2022

Availability

Academic Institutions and Nonprofits only

Showing: 21 - 40 of 93 results

Results per page:

Sort results by:

TRE-MPRA_minPromega Library

The Human Druggable CRISPR library

Human CRISPR Poison Exon Knockout Library

Liu Lab MusCK Library A

Liu Lab MusCK Library B

Wei lab paired-guide RNA (pgRNA) CRISPR–Cas9 library for human long non-coding RNAs (lncRNAs)

RLC11

DDR_MKOv4

RLC12

Humagne Set C

Humagne Set D

Pan-cancer CasRx lncRNA Albarossa library

SPECS library

S. rosetta Col- cDNA amplified library

hCRISPRi_dual_1_2

hCRISPRi_dual_3_4

Pan-Druggable Cancer Library

hCRISPRa_dual_1_2

Mouse Cardiac Transcriptional Regulators CRISPR Knockout Library

hCRISPRa_dual_3_4

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