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Human Epigenetic Knockout Library

Pooled Library

#162256

Purpose

Lentiviral CRISPR library targets human epigenetic genes

Depositor

Kivanc Birsoy

Article

Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Nov. 17, 2020

Availability

Academic Institutions and Nonprofits only
Human DNA Binding Domain-Focused CRISPR Knockout Library

Pooled Library

#123334

Purpose

Expresses gRNA targeting the DNA binding domain of human transcription factors.

Depositor

Christopher Vakoc

Article

Huang et al Genes Dev. 2018 Jul 1;32(13-14):915-928.

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

May 2, 2019

Availability

Academic Institutions and Nonprofits only
DNA repair library with 1,513 sgRNAs

Pooled Library

#177670

Purpose

CRISPR-interference (CRISPRi) library designed to target 476 genes involved in DNA repair and associated processes. It contains 1,513 sgRNAs and 60 non-targeting control sgRNAs.

Depositor

Brittany Adamson

Article

Chen et al Cell. 2021 Oct 28;184(22):5635-5652.e29.

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

July 11, 2023

Availability

Academic Institutions and Nonprofits only
Compact mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

Pooled Library

#136479

Purpose

Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

Depositor

Jonathan Weissman

Article

Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 25, 2020

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 Spike (S) Ectodomain Library C

Pooled Library

#157973

Purpose

Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

Depositor

Timothy Whitehead

Article

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Expression

Bacterial and Yeast

Species

Sars-cov-2

Available since

Sept. 13, 2021

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 Spike (S) Ectodomain Library B

Pooled Library

#157972

Purpose

Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

Depositor

Timothy Whitehead

Article

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Expression

Bacterial and Yeast

Species

Sars-cov-2

Available since

Sept. 13, 2021

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 Spike (S) Ectodomain Library A

Pooled Library

#157971

Purpose

Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

Depositor

Timothy Whitehead

Article

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Expression

Bacterial and Yeast

Species

Sars-cov-2

Available since

Sept. 13, 2021

Availability

Academic Institutions and Nonprofits only
Large-scale mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

Pooled Library

#136478

Purpose

Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

Depositor

Jonathan Weissman

Article

Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 25, 2020

Availability

Academic Institutions and Nonprofits only
TP53 MITE Library

Pooled Library

#113569

Purpose

Pooled lentiviral plasmid library containing ~8,000 single amino acid substitution and nonsense mutant variants of p53

Depositor

David Root, William Hahn

Article

Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available since

Jan. 4, 2019

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 1

Pooled Library

#168776

Purpose

Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

Depositor

Timothy Whitehead

Article

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Expression

Yeast

Species

Sars-cov-2

Available since

Sept. 13, 2021

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 2

Pooled Library

#168777

Purpose

Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

Depositor

Timothy Whitehead

Article

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Expression

Yeast

Species

Sars-cov-2

Available since

Sept. 13, 2021

Availability

Academic Institutions and Nonprofits only
ALL-PAM sensor Library

Pooled Library

#179219

Purpose

10 human and mouse sgRNAs each where for each sgRNA the tethered target site has 1 of 64 possible 3 bp PAM sequences.

Depositor

Lukas Dow

Article

Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

Expression

Mammalian

Use

Lentiviral

Available since

June 16, 2022

Availability

Academic Institutions and Nonprofits only
Human Base Editing Sensor Library

Pooled Library

#179218

Purpose

sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

Depositor

Lukas Dow

Article

Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

Expression

Mammalian

Use

Lentiviral

Available since

June 16, 2022

Availability

Academic Institutions and Nonprofits only
Mouse Base Editing Sensor Library

Pooled Library

#179217

Purpose

sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

Depositor

Lukas Dow

Article

Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

Expression

Mammalian

Use

Lentiviral

Available since

June 16, 2022

Availability

Academic Institutions and Nonprofits only
Barcode Library 1 (BCL1)

Pooled Library

#179852

Purpose

Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code CCAA.

Depositor

Jason Moffat

Article

Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

Expression

Mammalian

Use

Lentiviral

Available since

May 12, 2022

Availability

Academic Institutions and Nonprofits only
Barcode Library 0 (BCL0)

Pooled Library

#179851

Purpose

Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code ACGT.

Depositor

Jason Moffat

Article

Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

Expression

Mammalian

Use

Lentiviral

Available since

May 12, 2022

Availability

Academic Institutions and Nonprofits only
pEPIP_PepTile_40merFragments_65CancerDrivers

Pooled Library

#172109

Purpose

Lentiviral peptide expression library for overexpression fitness screening

Depositor

Prashant Mali

Article

Ford et al Cell Syst. 2021 Jul 21;12(7):716-732.e7.

Use

Lentiviral

Available since

Oct. 21, 2021

Availability

Academic Institutions and Nonprofits only
pSMAL-CellTag-V1

Pooled Library

#115643

Purpose

Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

Depositor

Samantha Morris

Article

Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

Has Service

Concentrated Lentiviral Prep

Expression

Mammalian

Species

Synthetic

Use

Lentiviral

Available since

Dec. 5, 2018

Availability

Academic Institutions and Nonprofits only
pSMAL-CellTag-V2

Pooled Library

#115644

Purpose

Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

Depositor

Samantha Morris

Article

Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

Has Service

Concentrated Lentiviral Prep

Expression

Mammalian

Species

Synthetic

Use

Lentiviral

Available since

Dec. 5, 2018

Availability

Academic Institutions and Nonprofits only
pSMAL-CellTag-V3

Pooled Library

#115645

Purpose

Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

Depositor

Samantha Morris

Article

Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

Has Service

Concentrated Lentiviral Prep

Expression

Mammalian

Species

Synthetic

Use

Lentiviral

Available since

Dec. 5, 2018

Availability

Academic Institutions and Nonprofits only

Showing: 21 - 40 of 41 results

Results per page:

Sort results by:

Human Epigenetic Knockout Library

Human DNA Binding Domain-Focused CRISPR Knockout Library

DNA repair library with 1,513 sgRNAs

Compact mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

SARS-CoV-2 Spike (S) Ectodomain Library C

SARS-CoV-2 Spike (S) Ectodomain Library B

SARS-CoV-2 Spike (S) Ectodomain Library A

Large-scale mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

TP53 MITE Library

SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 1

SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 2

ALL-PAM sensor Library

Human Base Editing Sensor Library

Mouse Base Editing Sensor Library

Barcode Library 1 (BCL1)

Barcode Library 0 (BCL0)

pEPIP_PepTile_40merFragments_65CancerDrivers

pSMAL-CellTag-V1

pSMAL-CellTag-V2

pSMAL-CellTag-V3

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